Does an Apple a Day Also Keep the Microbes Away? The Interplay Between Diet, Microbiota, and Host Defense Peptides at the Intestinal Mucosal Barrier

Feeding-dependent VIP neuron–ILC3 circuit regulates the intestinal barrier

(2020) Jhimmy Talbot et al.   NATURE

Effect of fructans, prebiotics and fibres on the human gut microbiome assessed by 16S rRNA-based approaches: a review

(2020) K.S. Swanson et al.   Beneficial Microbes

It's the fiber, not the fat: significant effects of dietary challenge on the gut microbiome

(2020) Kathleen E. Morrison et al.   Microbiome

An Update Review on the Paneth Cell as Key to Ileal Crohn's Disease

(2020) Jan Wehkamp et al.   Frontiers in Immunology

Paneth cell α-defensins HD-5 and HD-6 display differential degradation into active antimicrobial fragments

(2019) D. Ehmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human Paneth cell α-defensin 5 treatment reverses dyslipidemia and improves glucoregulatory capacity in diet-induced obese mice

(2019) Ida Søgaard Larsen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Nutrient Sensing by the Intestinal Epithelium Orchestrates Mucosal Antimicrobial Defense via Translational Control of Hes1

(2019) Shaonan Liang et al.   Cell Host & Microbe

Impact of Maternal Malnutrition on Gut Barrier Defense: Implications for Pregnancy Health and Fetal Development

(2019) Sebastian A. Srugo et al.   Nutrients

An Apple a Day: Which Bacteria Do We Eat With Organic and Conventional Apples?

(2019) Birgit Wassermann et al.   Frontiers in Microbiology

Vitamin D Regulates the Microbiota to Control the Numbers of RORγt/FoxP3+ Regulatory T Cells in the Colon

(2019) Margherita T. Cantorna et al.   Frontiers in Immunology

Macronutrient metabolism by the human gut microbiome: major fermentation by-products and their impact on host health

(2019) Kaitlyn Oliphant et al.   Microbiome

Diet–microbiota interactions and personalized nutrition

(2019) Aleksandra A. Kolodziejczyk et al.   NATURE REVIEWS MICROBIOLOGY

Epithelial Cells as a Transmitter of Signals From Commensal Bacteria and Host Immune Cells

(2019) Yoshiyuki Goto   Frontiers in Immunology

Western Diet and the Immune System: An Inflammatory Connection

(2019) Anette Christ et al.   IMMUNITY

Lypd8 inhibits attachment of pathogenic bacteria to colonic epithelia

(2019) Ryu Okumura et al.   Mucosal Immunology

IgA and the intestinal microbiota: the importance of being specific

(2019) Oliver Pabst et al.   Mucosal Immunology

Butyric Acid and Leucine Induce α-Defensin Secretion from Small Intestinal Paneth Cells

(2019) Akiko Takakuwa et al.   Nutrients

An Experimental Approach to Rigorously Assess Paneth Cell α-Defensin (Defa) mRNA Expression in C57BL/6 Mice

(2019) Patricia A. Castillo et al.   Scientific Reports

Microbiota and mucosal defense in IBD: an update

(2019) Eduard F. Stange et al.   Expert Review of Gastroenterology & Hepatology

Lipocalin 2 Protects Against Escherichia coli Infection by Modulating Neutrophil and Macrophage Function

(2019) Qianqian Wang et al.   Frontiers in Immunology

Neurotransmitter modulation by the gut microbiota

(2018) Philip Strandwitz   BRAIN RESEARCH

Bifidobacteria or Fiber Protects against Diet-Induced Microbiota-Mediated Colonic Mucus Deterioration

(2018) Bjoern O. Schroeder et al.   Cell Host & Microbe

Small Intestine Microbiota Regulate Host Digestive and Absorptive Adaptive Responses to Dietary Lipids

(2018) Kristina Martinez-Guryn et al.   Cell Host & Microbe

A cytokine network involving IL-36γ, IL-23, and IL-22 promotes antimicrobial defense and recovery from intestinal barrier damage

(2018) Vu L. Ngo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Enteric α-defensins on the verge of intestinal immune tolerance and inflammation

(2018) Dominik Filipp et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Oral Administration of Probiotics Increases Paneth Cells and Intestinal Antimicrobial Activity

(2018) Silvia I. Cazorla et al.   Frontiers in Microbiology

DIETARY FATTY ACIDS SUSTAIN GROWTH OF HUMAN GUT MICROBIOTA

(2018) Richard Agans et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Microbial tryptophan catabolites in health and disease

(2018) Henrik M. Roager et al.   Nature Communications

Thinking outside the cereal box: non-carbohydrate routes for dietary manipulation of the gut microbiota

(2018) Aspen T. Reese et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Rutin and Its Combination With Inulin Attenuate Gut Dysbiosis, the Inflammatory Status and Endoplasmic Reticulum Stress in Paneth Cells of Obese Mice Induced by High-Fat Diet

(2018) Xiulan Guo et al.   Frontiers in Microbiology

Microbial nitrogen limitation in the mammalian large intestine

(2018) Aspen T. Reese et al.   Nature Microbiology

Fight them or feed them: how the intestinal mucus layer manages the gut microbiota

(2018) Bjoern O Schroeder   Gastroenterology Report

Impact of dietary fat on gut microbiota and low-grade systemic inflammation: mechanisms and clinical implications on obesity

(2017) Flávia Galvão Cândido et al.   INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION

Circulating trimethylamine N-oxide and the risk of cardiovascular diseases: a systematic review and meta-analysis of 11 prospective cohort studies

(2017) Jiaqian Qi et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

The modulatory effect of polyphenols from green tea, oolong tea and black tea on human intestinal microbiota in vitro

(2017) Hanyang Sun et al.   JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE

Influence of diet on the gut microbiome and implications for human health

(2017) Rasnik K. Singh et al.   Journal of Translational Medicine

High Fat Diet Alters Gut Microbiota and the Expression of Paneth Cell-Antimicrobial Peptides Preceding Changes of Circulating Inflammatory Cytokines

(2017) Xiulan Guo et al.   MEDIATORS OF INFLAMMATION

Complex pectin metabolism by gut bacteria reveals novel catalytic functions

(2017) Didier Ndeh et al.   NATURE

Resistin-like molecule β is a bactericidal protein that promotes spatial segregation of the microbiota and the colonic epithelium

(2017) Daniel C. Propheter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dysbiosis of Intestinal Microbiota and Decreased Antimicrobial Peptide Level in Paneth Cells during Hypertriglyceridemia-Related Acute Necrotizing Pancreatitis in Rats

(2017) Chunlan Huang et al.   Frontiers in Microbiology

Ileal antimicrobial peptide expression is dysregulated in old age

(2017) Sarah Tremblay et al.   Immunity & Ageing

Obesogenic diet-induced gut barrier dysfunction and pathobiont expansion aggravate experimental colitis

(2017) June-Chul Lee et al.   PLoS One

Nutrition meets the microbiome: micronutrients and the microbiota

(2016) Hans K. Biesalski   Annals of the New York Academy of Sciences

α-Defensin 5 gene expression is regulated by gut microbial metabolites

(2016) Yutaka Sugi et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

From Dietary Fiber to Host Physiology: Short-Chain Fatty Acids as Key Bacterial Metabolites

(2016) Ara Koh et al.   CELL

A Dietary Fiber-Deprived Gut Microbiota Degrades the Colonic Mucus Barrier and Enhances Pathogen Susceptibility

(2016) Mahesh S. Desai et al.   CELL

Fine-tuning of the mucosal barrier and metabolic systems using the diet-microbial metabolite axis

(2016) Motoyoshi Nagai et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Lypd8 promotes the segregation of flagellated microbiota and colonic epithelia

(2016) Ryu Okumura et al.   NATURE

High-fat diet enhances stemness and tumorigenicity of intestinal progenitors

(2016) Semir Beyaz et al.   NATURE

Interactions between the microbiota and pathogenic bacteria in the gut

(2016) Andreas J. Bäumler et al.   NATURE

The microbiome and innate immunity

(2016) Christoph A. Thaiss et al.   NATURE

Diet–microbiota interactions as moderators of human metabolism

(2016) Justin L. Sonnenburg et al.   NATURE

Diet-induced extinctions in the gut microbiota compound over generations

(2016) Erica D. Sonnenburg et al.   NATURE

Signals from the gut microbiota to distant organs in physiology and disease

(2016) Bjoern O Schroeder et al.   NATURE MEDICINE

Role of gut microbiota in atherosclerosis

(2016) Annika Lindskog Jonsson et al.   Nature Reviews Cardiology

Short chain fatty acids and gut microbiota differ between patients with Parkinson's disease and age-matched controls

(2016) Marcus M. Unger et al.   PARKINSONISM & RELATED DISORDERS

Gram-positive bacteria are held at a distance in the colon mucus by the lectin-like protein ZG16

(2016) Joakim H. Bergström et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High-fat diet modifies the PPAR-γ pathway leading to disruption of microbial and physiological ecosystem in murine small intestine

(2016) Julie Tomas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Population-based metagenomics analysis reveals markers for gut microbiome composition and diversity

(2016) Alexandra Zhernakova et al.   SCIENCE

The Reciprocal Interactions between Polyphenols and Gut Microbiota and Effects on Bioaccessibility

(2016) Tugba Ozdal et al.   Nutrients

Vitamin D Signaling through Induction of Paneth Cell Defensins Maintains Gut Microbiota and Improves Metabolic Disorders and Hepatic Steatosis in Animal Models

(2016) Danmei Su et al.   Frontiers in Physiology

Impact of Dietary Lipids on Colonic Function and Microbiota: An Experimental Approach Involving Orlistat-Induced Fat Malabsorption in Human Volunteers

(2016) Pamela Morales et al.   Clinical and Translational Gastroenterology

Dietary fat and gut microbiota interactions determine diet-induced obesity in mice

(2016) Raphaela Kübeck et al.   Molecular Metabolism

Interleukin-25 Mediated Induction of Angiogenin-4 Is Interleukin-13 Dependent

(2016) Zannatun Noor et al.   PLoS One

Relationship of Serum Trimethylamine N-Oxide (TMAO) Levels with early Atherosclerosis in Humans

(2016) Elko Randrianarisoa et al.   Scientific Reports

Three decades of research on angiogenin: a review and perspective

(2015) Jinghao Sheng et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Review article: insights into colonic protein fermentation, its modulation and potential health implications

(2015) C. K. Yao et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Deletion of intestinal epithelial insulin receptor attenuates high-fat diet-induced elevations in cholesterol and stem, enteroendocrine, and Paneth cell mRNAs

(2015) Sarah F. Andres et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Interleukin-22: Immunobiology and Pathology

(2015) Jarrod A. Dudakov et al.   Annual Review of Immunology

Microbiota-Modulated Metabolites Shape the Intestinal Microenvironment by Regulating NLRP6 Inflammasome Signaling

(2015) Maayan Levy et al.   CELL

Microbiota in Allergy and Asthma and the Emerging Relationship with the Gut Microbiome

(2015) Kei E. Fujimura et al.   Cell Host & Microbe

Gut Microbiome: Westernization and the Disappearance of Intestinal Diversity

(2015) Nicola Segata   CURRENT BIOLOGY

Influence of high-fat diet on gut microbiota

(2015) E. Angela Murphy et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Dysbiotic gut microbiota causes transmissible Crohn's disease-like ileitis independent of failure in antimicrobial defence

(2015) Monika Schaubeck et al.   GUT

Antimicrobial Defense of the Intestine

(2015) Sohini Mukherjee et al.   IMMUNITY

White and dark kidney beans reduce colonic mucosal damage and inflammation in response to dextran sodium sulfate

(2015) Jennifer M. Monk et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome

(2015) Benoit Chassaing et al.   NATURE

Activation of HIF-1α and LL-37 by commensal bacteria inhibits Candida albicans colonization

(2015) Di Fan et al.   NATURE MEDICINE

Global Profiling of Carbohydrate Active Enzymes in Human Gut Microbiome

(2015) Tanudeep Bhattacharya et al.   PLoS One

Antimicrobial peptide resistance mediates resilience of prominent gut commensals during inflammation

(2015) T. W. Cullen et al.   SCIENCE

Chronic Zinc Deficiency Alters Chick Gut Microbiota Composition and Function

(2015) Spenser Reed et al.   Nutrients

Rethinking “Enterotypes”

(2014) Dan Knights et al.   Cell Host & Microbe

Starving our Microbial Self: The Deleterious Consequences of a Diet Deficient in Microbiota-Accessible Carbohydrates

(2014) Erica D. Sonnenburg et al.   Cell Metabolism

Microbiome of prebiotic-treated mice reveals novel targets involved in host response during obesity

(2014) Amandine Everard et al.   ISME Journal

Paneth cell extrusion and release of antimicrobial products is directly controlled by immune cell–derived IFN-γ

(2014) Henner F. Farin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

TRIF Signaling Drives Homeostatic Intestinal Epithelial Antimicrobial Peptide Expression

(2014) Silvia Stockinger et al.   JOURNAL OF IMMUNOLOGY

Paneth cell α-defensin 6 (HD-6) is an antimicrobial peptide

(2014) B O Schroeder et al.   Mucosal Immunology

Artificial sweeteners induce glucose intolerance by altering the gut microbiota

(2014) Jotham Suez et al.   NATURE

Gut microbiome of the Hadza hunter-gatherers

(2014) Stephanie L. Schnorr et al.   Nature Communications

Differential Induction of Antimicrobial REGIII by the Intestinal Microbiota and Bifidobacterium breve NCC2950

(2013) Jane M. M. Natividad et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Tryptophan Catabolites from Microbiota Engage Aryl Hydrocarbon Receptor and Balance Mucosal Reactivity via Interleukin-22

(2013) Teresa Zelante et al.   IMMUNITY

Human colonic mucus is a reservoir for antimicrobial peptides

(2013) Lena Antoni et al.   Journal of Crohns & Colitis

Fundamental role for HIF-1α in constitutive expression of human β defensin-1

(2013) C J Kelly et al.   Mucosal Immunology

Antibacterial membrane attack by a pore-forming intestinal C-type lectin

(2013) Sohini Mukherjee et al.   NATURE

Diet rapidly and reproducibly alters the human gut microbiome

(2013) Lawrence A. David et al.   NATURE

Paneth cells as a site of origin for intestinal inflammation

(2013) Timon E. Adolph et al.   NATURE

The carbohydrate-active enzymes database (CAZy) in 2013

(2013) Vincent Lombard et al.   NUCLEIC ACIDS RESEARCH

Human intestinal microbiota composition is associated with local and systemic inflammation in obesity

(2013) Froukje J. Verdam et al.   Obesity

Intestinal Intraepithelial Lymphocyte-Enterocyte Crosstalk Regulates Production of Bactericidal Angiogenin 4 by Paneth Cells upon Microbial Challenge

(2013) Catherine R. Walker et al.   PLoS One

Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity

(2013) A. Everard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gut Microbiota from Twins Discordant for Obesity Modulate Metabolism in Mice

(2013) V. K. Ridaura et al.   SCIENCE

Dysbiosis—A consequence of Paneth cell dysfunction

(2013) Nita H. Salzman et al.   SEMINARS IN IMMUNOLOGY

Influence of red wine polyphenols and ethanol on the gut microbiota ecology and biochemical biomarkers

(2012) María Isabel Queipo-Ortuño et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Interleukin 23 Production by Intestinal CD103+CD11b+ Dendritic Cells in Response to Bacterial Flagellin Enhances Mucosal Innate Immune Defense

(2012) Melissa A. Kinnebrew et al.   IMMUNITY

Structural resilience of the gut microbiota in adult mice under high-fat dietary perturbations

(2012) Chenhong Zhang et al.   ISME Journal

Alternative Luminal Activation Mechanisms for Paneth Cell α-Defensins

(2012) Jennifer R. Mastroianni et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bacterial Stimulation of the TLR-MyD88 Pathway Modulates the Homeostatic Expression of Ileal Paneth Cell α-Defensins

(2012) A. Menendez et al.   Journal of Innate Immunity

Total Parenteral Nutrition Induces a Shift in the Firmicutes to Bacteroidetes Ratio in Association with Paneth Cell Activation in Rats

(2012) Caroline M. Hodin et al.   JOURNAL OF NUTRITION

Role of nutrition and microbiota in susceptibility to inflammatory bowel diseases

(2012) Liljana Gentschew et al.   MOLECULAR NUTRITION & FOOD RESEARCH

CRS-peptides: unique defense peptides of mouse Paneth cells

(2012) M L Andersson et al.   Mucosal Immunology

A metagenome-wide association study of gut microbiota in type 2 diabetes

(2012) Junjie Qin et al.   NATURE

Human gut microbiome viewed across age and geography

(2012) Tanya Yatsunenko et al.   NATURE

How glycan metabolism shapes the human gut microbiota

(2012) Nicole M. Koropatkin et al.   NATURE REVIEWS MICROBIOLOGY

Digested and Fermented Green Kiwifruit Increases Human β-Defensin 1 and 2 Production In vitro

(2012) Kerry L. Bentley-Hewitt et al.   PLANT FOODS FOR HUMAN NUTRITION

In vitro Utilization of Gold and Green Kiwifruit Oligosaccharides by Human Gut Microbial Populations

(2012) Shanthi G. Parkar et al.   PLANT FOODS FOR HUMAN NUTRITION

Iron Availability Increases the Pathogenic Potential of Salmonella Typhimurium and Other Enteric Pathogens at the Intestinal Epithelial Interface

(2012) Guus A. M. Kortman et al.   PLoS One

Human  -Defensin 6 Promotes Mucosal Innate Immunity Through Self-Assembled Peptide Nanonets

(2012) H. Chu et al.   SCIENCE

PPARs at the crossroads of lipid signaling and inflammation

(2012) Walter Wahli et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Starvation Compromises Paneth Cells

(2011) Caroline M. Hodin et al.   AMERICAN JOURNAL OF PATHOLOGY

Reduced Paneth cell antimicrobial protein levels correlate with activation of the unfolded protein response in the gut of obese individuals

(2011) Caroline M Hodin et al.   JOURNAL OF PATHOLOGY

Enterotypes of the human gut microbiome

(2011) Manimozhiyan Arumugam et al.   NATURE

Paneth cells, antimicrobial peptides and maintenance of intestinal homeostasis

(2011) Charles L. Bevins et al.   NATURE REVIEWS MICROBIOLOGY

Depletion of Murine Intestinal Microbiota: Effects on Gut Mucosa and Epithelial Gene Expression

(2011) Dag Henrik Reikvam et al.   PLoS One

The Antibacterial Lectin RegIII  Promotes the Spatial Segregation of Microbiota and Host in the Intestine

(2011) S. Vaishnava et al.   SCIENCE

Dietary fibre and fibre-rich by-products of food processing: Characterisation, technological functionality and commercial applications: A review

(2010) Mohamed Elleuch et al.   FOOD CHEMISTRY

Bactericidal Activity of Mouse α-Defensin Cryptdin-4 Predominantly Affects Noncommensal Bacteria

(2010) Koji Masuda et al.   Journal of Innate Immunity

Gut Microbiota in Human Adults with Type 2 Diabetes Differs from Non-Diabetic Adults

(2010) Nadja Larsen et al.   PLoS One

Comparative Analysis of Fecal Microbiota in Infants with and without Eczema

(2010) Pei-Ying Hong et al.   PLoS One

Peroxisome proliferator-activated receptor gamma activation is required for maintenance of innate antimicrobial immunity in the colon

(2010) L. Peyrin-Biroulet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa

(2010) C. De Filippo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lipocalin-2 Resistance Confers an Advantage to Salmonella enterica Serotype Typhimurium for Growth and Survival in the Inflamed Intestine

(2009) Manuela Raffatellu et al.   Cell Host & Microbe

The role of pH in determining the species composition of the human colonic microbiota

(2009) Sylvia H. Duncan et al.   ENVIRONMENTAL MICROBIOLOGY

High-Fat Diet Determines the Composition of the Murine Gut Microbiome Independently of Obesity

(2009) Marie A. Hildebrandt et al.   GASTROENTEROLOGY

Interaction between Phenolics and Gut Microbiota: Role in Human Health

(2009) María V. Selma et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Probiotic E. coli treatment mediates antimicrobial human β-defensin synthesis and fecal excretion in humans

(2009) M Möndel et al.   Mucosal Immunology

Enteric defensins are essential regulators of intestinal microbial ecology

(2009) Nita H Salzman et al.   NATURE IMMUNOLOGY

Reducing endoplasmic reticulum stress through a macrophage lipid chaperone alleviates atherosclerosis

(2009) Ebru Erbay et al.   NATURE MEDICINE

Regional variations in Paneth cell antimicrobial peptide expression along the mouse intestinal tract

(2008) Jenny Karlsson et al.   BMC IMMUNOLOGY

XBP1 Links ER Stress to Intestinal Inflammation and Confers Genetic Risk for Human Inflammatory Bowel Disease

(2008) Arthur Kaser et al.   CELL

Diet-Induced Obesity Is Linked to Marked but Reversible Alterations in the Mouse Distal Gut Microbiome

(2008) Peter J. Turnbaugh et al.   Cell Host & Microbe

Reduced  -defensin expression is associated with inflammation and not NOD2 mutation status in ileal Crohn's disease

(2008) L A Simms et al.   GUT

Secreted enteric antimicrobial activity localises to the mucus surface layer

(2008) U Meyer-Hoffert et al.   GUT

IL-22 ameliorates intestinal inflammation in a mouse model of ulcerative colitis

(2008) Ken Sugimoto et al.   JOURNAL OF CLINICAL INVESTIGATION

Developmental switch of intestinal antimicrobial peptide expression

(2008) Sandrine Ménard et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells

(2008) Ken Cadwell et al.   NATURE

Innate immunity and intestinal microbiota in the development of Type 1 diabetes

(2008) Li Wen et al.   NATURE

Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens

(2008) Yan Zheng et al.   NATURE MEDICINE

Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface

(2008) S. Vaishnava et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Novel role of the vitamin D receptor in maintaining the integrity of the intestinal mucosal barrier

(2007) Juan Kong et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY