Role of gut microbiota in atherosclerosis

The Carnitine-butyrobetaine-trimethylamine-N-oxide pathway and its association with cardiovascular mortality in patients with carotid atherosclerosis

(2016) Karolina Skagen et al.   ATHEROSCLEROSIS

L-Carnitine intake and high trimethylamine N-oxide plasma levels correlate with low aortic lesions in ApoE−/− transgenic mice expressing CETP

(2016) Heidi L. Collins et al.   ATHEROSCLEROSIS

Saturated fatty acids trigger TLR4-mediated inflammatory response

(2016) D.M. Rocha et al.   ATHEROSCLEROSIS

Gut Microbial Metabolite TMAO Enhances Platelet Hyperreactivity and Thrombosis Risk

(2016) Weifei Zhu et al.   CELL

Intestinal Crosstalk between Bile Acids and Microbiota and Its Impact on Host Metabolism

(2016) Annika Wahlström et al.   Cell Metabolism

Akkermansia MuciniphilaProtects Against Atherosclerosis by Preventing Metabolic Endotoxemia-Induced Inflammation inApoe−/−MiceCLINICAL PERSPECTIVE

(2016) Jin Li et al.   CIRCULATION

Analysis of Gut Microbiota in Coronary Artery Disease Patients: a Possible Link between Gut Microbiota and Coronary Artery Disease

(2016) Takuo Emoto et al.   Journal of Atherosclerosis and Thrombosis

Diet–microbiota interactions as moderators of human metabolism

(2016) Justin L. Sonnenburg et al.   NATURE

Adapting Koch's postulates

(2016) A. L. Byrd et al.   SCIENCE

Resveratrol Attenuates Trimethylamine- N -Oxide (TMAO)-Induced Atherosclerosis by Regulating TMAO Synthesis and Bile Acid Metabolism via Remodeling of the Gut Microbiota

(2016) Ming-liang Chen et al.   mBio

Trimethylamine N‐Oxide Promotes Vascular Inflammation Through Signaling of Mitogen‐Activated Protein Kinase and Nuclear Factor‐κB

(2016) Marcus M. Seldin et al.   Journal of the American Heart Association

Oral microbiota in patients with atherosclerosis

(2015) Frida Fåk et al.   ATHEROSCLEROSIS

The Relationship Between Trimethylamine-N-Oxide and Prevalent Cardiovascular Disease in a Multiethnic Population Living in Canada

(2015) Andrew Mente et al.   CANADIAN JOURNAL OF CARDIOLOGY

Non-lethal Inhibition of Gut Microbial Trimethylamine Production for the Treatment of Atherosclerosis

(2015) Zeneng Wang et al.   CELL

Roux-en-Y Gastric Bypass and Vertical Banded Gastroplasty Induce Long-Term Changes on the Human Gut Microbiome Contributing to Fat Mass Regulation

(2015) Valentina Tremaroli et al.   Cell Metabolism

Crosstalk between Gut Microbiota and Dietary Lipids Aggravates WAT Inflammation through TLR Signaling

(2015) Robert Caesar et al.   Cell Metabolism

The Gut Microbiome Contributes to a Substantial Proportion of the Variation in Blood LipidsNovelty and Significance

(2015) Jingyuan Fu et al.   CIRCULATION RESEARCH

Food, Immunity, and the Microbiome

(2015) Herbert Tilg et al.   GASTROENTEROLOGY

Genetic and environmental control of host-gut microbiota interactions

(2015) Elin Org et al.   GENOME RESEARCH

Intestinal Microbiota-Dependent Phosphatidylcholine Metabolites, Diastolic Dysfunction, and Adverse Clinical Outcomes in Chronic Systolic Heart Failure

(2015) W.H. Wilson Tang et al.   JOURNAL OF CARDIAC FAILURE

Metabonomic Changes Associated with Atherosclerosis Progression for LDLR–/– Mice

(2015) Dan Li et al.   JOURNAL OF PROTEOME RESEARCH

Chlamydia pneumoniae-Mediated Inflammation in Atherosclerosis: A Meta-Analysis

(2015) Simone Filardo et al.   MEDIATORS OF INFLAMMATION

Intestinal Microbiota Composition Modulates Choline Bioavailability from Diet and Accumulation of the Proatherogenic Metabolite Trimethylamine- N -Oxide

(2015) Kymberleigh A. Romano et al.   mBio

Flavin-containing monooxygenase 3 as a potential player in diabetes-associated atherosclerosis

(2015) Ji Miao et al.   Nature Communications

Intestine-selective farnesoid X receptor inhibition improves obesity-related metabolic dysfunction

(2015) Changtao Jiang et al.   Nature Communications

The TMAO-Generating Enzyme Flavin Monooxygenase 3 Is a Central Regulator of Cholesterol Balance

(2015) Manya Warrier et al.   Cell Reports

Genetic Architecture of Atherosclerosis in Mice: A Systems Genetics Analysis of Common Inbred Strains

(2015) Brian J. Bennett et al.   PLoS Genetics

In silico analyses of metagenomes from human atherosclerotic plaque samples

(2015) Suparna Mitra et al.   Microbiome

γ-Butyrobetaine Is a Proatherogenic Intermediate in Gut Microbial Metabolism of L -Carnitine to TMAO

(2014) Robert A. Koeth et al.   Cell Metabolism

Prognostic value of choline and betaine depends on intestinal microbiota-generated metabolite trimethylamine-N-oxide

(2014) Z. Wang et al.   EUROPEAN HEART JOURNAL

Transmission of Atherosclerosis Susceptibility with Gut Microbial Transplantation

(2014) Jill C. Gregory et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Intestinal farnesoid X receptor signaling promotes nonalcoholic fatty liver disease

(2014) Changtao Jiang et al.   JOURNAL OF CLINICAL INVESTIGATION

Microbiota-dependent metabolite trimethylamine-N-oxide is associated with disease severity and survival of patients with chronic heart failure

(2014) M. Trøseid et al.   JOURNAL OF INTERNAL MEDICINE

Flavin containing monooxygenase 3 exerts broad effects on glucose and lipid metabolism and atherosclerosis

(2014) Diana M. Shih et al.   JOURNAL OF LIPID RESEARCH

Exopolysaccharide-Producing Probiotic Lactobacilli Reduce Serum Cholesterol and Modify Enteric Microbiota in ApoE-Deficient Mice

(2014) Lis EE London et al.   JOURNAL OF NUTRITION

Prognostic Value of Elevated Levels of Intestinal Microbe-Generated Metabolite Trimethylamine-N-Oxide in Patients With Heart Failure

(2014) W.H. Wilson Tang et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Responsiveness of cardiometabolic-related microbiota to diet is influenced by host genetics

(2014) Annalouise O’Connor et al.   MAMMALIAN GENOME

An integrated catalog of reference genes in the human gut microbiome

(2014) Junhua Li et al.   NATURE BIOTECHNOLOGY

Oral Supplementation with Non-Absorbable Antibiotics or Curcumin Attenuates Western Diet-Induced Atherosclerosis and Glucose Intolerance in LDLR−/− Mice – Role of Intestinal Permeability and Macrophage Activation

(2014) Siddhartha S. Ghosh et al.   PLoS One

Dual Activation of the Bile Acid Nuclear Receptor FXR and G-Protein-Coupled Receptor TGR5 Protects Mice against Atherosclerosis

(2014) Shinobu Miyazaki-Anzai et al.   PLoS One

Gut Microbiota Regulates Bile Acid Metabolism by Reducing the Levels of Tauro-beta-muricholic Acid, a Naturally Occurring FXR Antagonist

(2013) Sama I. Sayin et al.   Cell Metabolism

Trimethylamine-N-Oxide, a Metabolite Associated with Atherosclerosis, Exhibits Complex Genetic and Dietary Regulation

(2013) Brian J. Bennett et al.   Cell Metabolism

Gut metagenome in European women with normal, impaired and diabetic glucose control

(2013) Fredrik H. Karlsson et al.   NATURE

Intestinal microbiota metabolism of l-carnitine, a nutrient in red meat, promotes atherosclerosis

(2013) Robert A Koeth et al.   NATURE MEDICINE

The gut microbiota — masters of host development and physiology

(2013) Felix Sommer et al.   NATURE REVIEWS MICROBIOLOGY

Intestinal Microbial Metabolism of Phosphatidylcholine and Cardiovascular Risk

(2013) W.H. Wilson Tang et al.   NEW ENGLAND JOURNAL OF MEDICINE

Microbial composition of atherosclerotic plaques

(2013) CA Calandrini et al.   ORAL DISEASES

Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity

(2013) A. Everard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fiber and Prebiotics: Mechanisms and Health Benefits

(2013) Joanne Slavin   Nutrients

Cardiovascular disease after Escherichia coli O157:H7 gastroenteritis

(2012) P. Hizo-Abes et al.   CANADIAN MEDICAL ASSOCIATION JOURNAL

A High-Fat Diet Is Associated With Endotoxemia That Originates From the Gut

(2012) Swaroop Pendyala et al.   GASTROENTEROLOGY

Antibiotics in early life alter the murine colonic microbiome and adiposity

(2012) Ilseung Cho et al.   NATURE

Structure, function and diversity of the healthy human microbiome

(2012)   NATURE

Lactobacillus reuteri Prevents Diet-Induced Obesity, but not Atherosclerosis, in a Strain Dependent Fashion in Apoe−/− Mice

(2012) Frida Fåk et al.   PLoS One

Lack of association between TLR4 Asp299Gly polymorphism and atherosclerosis: evidence from meta-analysis

(2012) Kui Zhang et al.   THROMBOSIS RESEARCH

Symptomatic atherosclerosis is associated with an altered gut metagenome

(2012) Fredrik H. Karlsson et al.   Nature Communications

Absence of Microbiota (Germ-Free Conditions) Accelerates the Atherosclerosis in ApoE-Deficient Mice Fed Standard Low Cholesterol Diet

(2011) Renata Stepankova et al.   Journal of Atherosclerosis and Thrombosis

Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease

(2011) Zeneng Wang et al.   NATURE

Pathogens and atherosclerosis: Update on the potential contribution of multiple infectious organisms to the pathogenesis of atherosclerosis

(2011) Lee Ann Campbell et al.   THROMBOSIS AND HAEMOSTASIS

Porphyromonas gingivalis accelerates inflammatory atherosclerosis in the innominate artery of ApoE deficient mice

(2010) Chie Hayashi et al.   ATHEROSCLEROSIS

Aggregatibacter actinomycetemcomitansaccelerates atherosclerosis with an increase in atherogenic factors in spontaneously hyperlipidemic mice

(2010) Tao Zhang et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

Pathogen-Mediated Inflammatory Atherosclerosis Is Mediated in Part via Toll-Like Receptor 2-Induced Inflammatory Responses

(2010) Chie Hayashi et al.   Journal of Innate Immunity

A human gut microbial gene catalogue established by metagenomic sequencing

(2010) Junjie Qin et al.   NATURE

Human oral, gut, and plaque microbiota in patients with atherosclerosis

(2010) O. Koren et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Infectious Burden and Carotid Plaque Thickness

(2010) Mitchell S.V. Elkind et al.   STROKE

THE RELATIONSHIP BETWEEN PERIODONTAL DISEASE (PD) AND CARDIOVASCULAR DISEASE (CVD).

(2010) Maurizio Trevisan et al.   Mediterranean Journal of Hematology and Infectious Diseases

Probiotic therapy to men with incipient arteriosclerosis initiates increased bacterial diversity in colon: A randomized controlled trial

(2009) Caroline Karlsson et al.   ATHEROSCLEROSIS

Insights Into the Role of Infection in Atherogenesis and in Plaque Rupture

(2009) Stephen E. Epstein et al.   CIRCULATION

Effect of fermented milk containing Lactobacillus acidophilus and Bifidobacterium longum on plasma lipids of women with normal or moderately elevated cholesterol

(2009) Sara Andrade et al.   JOURNAL OF DAIRY RESEARCH

Activation of farnesoid X receptor prevents atherosclerotic lesion formation in LDLR−/−and apoE−/−mice

(2009) Helen B. Hartman et al.   JOURNAL OF LIPID RESEARCH

The gut microbiota modulates host energy and lipid metabolism in mice

(2009) Vidya R. Velagapudi et al.   JOURNAL OF LIPID RESEARCH

Role of Bile Acids and Bile Acid Receptors in Metabolic Regulation

(2009) Philippe Lefebvre et al.   PHYSIOLOGICAL REVIEWS

Antiatherosclerotic effect of farnesoid X receptor

(2008) Andrea Mencarelli et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY