The Gut Microbiota and Its Metabolites, Novel Targets for Treating and Preventing Non‐Alcoholic Fatty Liver Disease

TMAVA, a Metabolite of Intestinal Microbes, Is Increased in Plasma From Patients With Liver Steatosis, Inhibits γ-butyrobetaine Hydroxylase, and Exacerbates Fatty Liver in Mice

(2020) Mingming Zhao et al.   GASTROENTEROLOGY

Adipose Tissue Macrophage Phenotypes and Characteristics: The Key to Insulin Resistance in Obesity and Metabolic Disorders

(2020) Yinhua Ni et al.   Obesity

Insights into the role of bacteria in vitamin A biosynthesis: Future research opportunities

(2019) K. Srinivasan et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Gut microbial metabolites in obesity, NAFLD and T2DM

(2019) Emanuel E. Canfora et al.   Nature Reviews Endocrinology

Interactions between gut microbiota and non-alcoholic liver disease: the role of microbiota-derived metabolites

(2019) Yufang Ding et al.   PHARMACOLOGICAL RESEARCH

Gut microbiota: novel therapeutic target for nonalcoholic fatty liver disease

(2019) Ki Tae Suk et al.   Expert Review of Gastroenterology & Hepatology

Modulation of fat metabolism and gut microbiota by resveratrol on high-fat diet-induced obese mice

(2019) C. Linda Campbell et al.   Diabetes Metabolic Syndrome and Obesity-Targets and Therapy

A gut microbiome signature for cirrhosis due to nonalcoholic fatty liver disease

(2019) Cyrielle Caussy et al.   Nature Communications

IL1R1 is required for celastrol’s leptin-sensitization and antiobesity effects

(2019) Xudong Feng et al.   NATURE MEDICINE

Functional Interactions between Gut Microbiota Transplantation, Quercetin, and High-Fat Diet Determine Non-Alcoholic Fatty Liver Disease Development in Germ-Free Mice

(2019) David Porras et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Role of gut microbial metabolites in nonalcoholic fatty liver disease

(2019) Ze Hua Zhao et al.   Journal of Digestive Diseases

Gut dysbiosis-derived exosomes trigger hepatic steatosis by transiting HMGB1 from intestinal to liver in mice

(2019) Yu Chen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Beneficial effects of exercise on gut microbiota functionality and barrier integrity, and gut-liver crosstalk in an in vivo model of early obesity and non-alcoholic fatty liver disease

(2019) Sara Carbajo-Pescador et al.   Disease Models & Mechanisms

Impact of bacterial probiotics on obesity, diabetes and non-alcoholic fatty liver disease related variables: a systematic review and meta-analysis of randomised controlled trials

(2019) Hana Koutnikova et al.   BMJ Open

Crosstalk between adipose tissue insulin resistance and liver macrophages in Non Alcoholic Fatty Liver Disease

(2019) Chiara Rosso et al.   JOURNAL OF HEPATOLOGY

Xanthophyllomyces dendrorhous-Derived Astaxanthin Regulates Lipid Metabolism and Gut Microbiota in Obese Mice Induced by A High-Fat Diet

(2019) Jihui Wang et al.   Marine Drugs

A Network Involving Gut Microbiota, Circulating Bile Acids, and Hepatic Metabolism Genes That Protects Against Non‐Alcoholic Fatty Liver Disease

(2019) Petar Dianov Petrov et al.   MOLECULAR NUTRITION & FOOD RESEARCH

My Doctor Told Me I Have Fatty Liver—What Do I Need to Know?

(2019) Elizabeth S. Aby et al.   JAMA Internal Medicine

Understanding the Role of the Gut Microbiome and Microbial Metabolites in Obesity and Obesity-Associated Metabolic Disorders: Current Evidence and Perspectives

(2019) Natalia Vallianou et al.   Current Obesity Reports

Review article: can bugs be drugs? The potential of probiotics and prebiotics as treatment for non-alcoholic fatty liver disease

(2019) Nienke Koopman et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Microbiota-driven gut vascular barrier disruption is a prerequisite for non-alcoholic steatohepatitis development

(2019) Juliette Mouries et al.   JOURNAL OF HEPATOLOGY

Lycopene Alleviates Obesity‐Induced Inflammation and Insulin Resistance by Regulating M1/M2 Status of Macrophages

(2019) Guanliang Chen et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Lactobacillus and Bifidobacterium Improves Physiological Function and Cognitive Ability in Aged Mice by the Regulation of Gut Microbiota

(2019) Yinhua Ni et al.   MOLECULAR NUTRITION & FOOD RESEARCH

BCAA catabolism in brown fat controls energy homeostasis through SLC25A44

(2019) Takeshi Yoneshiro et al.   NATURE

Regulatory effect of a Chinese herbal medicine formula on non-alcoholic fatty liver disease

(2019) Jia-Min Yang et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Gut Dysfunction and Non-alcoholic Fatty Liver Disease

(2019) Felix Grabherr et al.   Frontiers in Endocrinology

Turnover of bile acids in liver, serum and caecal content by high-fat diet feeding affects hepatic steatosis in rats

(2019) Yingyue Tang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Lycopene prevents the progression of lipotoxicity-induced nonalcoholic steatohepatitis by decreasing oxidative stress in mice

(2019) Yinhua Ni et al.   FREE RADICAL BIOLOGY AND MEDICINE

The gut-liver axis in liver disease: pathophysiological basis for therapy

(2019) Agustín Albillos et al.   JOURNAL OF HEPATOLOGY

Mastiha ( Pistacia lentiscus ) Improves Gut Microbiota Diversity, Hepatic Steatosis, and Disease Activity in a Biopsy‐Confirmed Mouse Model of Advanced Non‐Alcoholic Steatohepatitis and Fibrosis

(2019) Aimo Kannt et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Indole-3-Acetic Acid Alleviates Nonalcoholic Fatty Liver Disease in Mice via Attenuation of Hepatic Lipogenesis, and Oxidative and Inflammatory Stress

(2019) Yun Ji et al.   Nutrients

Relationship between Changes in Microbiota and Liver Steatosis Induced by High-Fat Feeding—A Review of Rodent Models

(2019) Saioa Gómez-Zorita et al.   Nutrients

The Role of Probiotics in Nonalcoholic Fatty Liver Disease: A New Insight into Therapeutic Strategies

(2019) Marica Meroni et al.   Nutrients

Gut Microbiota Regulation of Tryptophan Metabolism in Health and Disease

(2018) Allison Agus et al.   Cell Host & Microbe

Exercise has the guts: How physical activity may positively modulate gut microbiota in chronic and immune-based diseases

(2018) Roberto Codella et al.   DIGESTIVE AND LIVER DISEASE

The gut microbiota metabolite indole alleviates liver inflammation in mice

(2018) Martin Beaumont et al.   FASEB JOURNAL

PNPLA3: A Determinant of Response to Low-Fructose Diet in Nonalcoholic Fatty Liver Disease

(2018) Luke J. McGeoch et al.   GASTROENTEROLOGY

The Effects of Physical Exercise on Fatty Liver Disease

(2018) Dirk J. van der Windt et al.   GENE EXPRESSION

Gut commensalParabacteroides goldsteiniiplays a predominant role in the anti-obesity effects of polysaccharides isolated fromHirsutella sinensis

(2018) Tsung-Ru Wu et al.   GUT

Determinants of fibrosis progression and regression in NASH

(2018) Detlef Schuppan et al.   JOURNAL OF HEPATOLOGY

Molecular phenomics and metagenomics of hepatic steatosis in non-diabetic obese women

(2018) Lesley Hoyles et al.   NATURE MEDICINE

Mechanisms of NAFLD development and therapeutic strategies

(2018) Scott L. Friedman et al.   NATURE MEDICINE

Genetic deficiency of indoleamine 2,3-dioxygenase promotes gut microbiota-mediated metabolic health

(2018) Ludivine Laurans et al.   NATURE MEDICINE

Gut microbiome composition in lean patients with NASH is associated with liver damage independent of caloric intake: A prospective pilot study

(2018) S.M.B. Duarte et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

Chemoproteomics reveals baicalin activates hepatic CPT1 to ameliorate diet-induced obesity and hepatic steatosis

(2018) Jianye Dai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Liver–Microbiome Axis in Health and Disease

(2018) Timon E. Adolph et al.   TRENDS IN IMMUNOLOGY

Pathogenesis of non-alcoholic fatty liver disease in children and adolescence: From “two hit theory” to “multiple hit model”

(2018) Yan-Lan Fang et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Gut Microbiota-Derived Tryptophan Metabolites Modulate Inflammatory Response in Hepatocytes and Macrophages

(2018) Smitha Krishnan et al.   Cell Reports

Functional Gut Microbiota Remodeling Contributes to the Caloric Restriction-Induced Metabolic Improvements

(2018) Salvatore Fabbiano et al.   Cell Metabolism

Emerging Role of the Gut Microbiome in Nonalcoholic Fatty Liver Disease: From Composition to Function

(2018) S.R. Sharpton et al.   Clinical Gastroenterology and Hepatology

Celastrol Induced Weight Loss is Driven by Hypophagia and Independent From UCP1

(2018) Katrin Pfuhlmann et al.   DIABETES

Small metabolites, possible big changes: a microbiota-centered view of non-alcoholic fatty liver disease

(2018) Huikuan Chu et al.   GUT

Diammonium Glycyrrhizinate Protects against Nonalcoholic Fatty Liver Disease in Mice through Modulation of Gut Microbiota and Restoration of Intestinal Barrier

(2018) Yun Li et al.   MOLECULAR PHARMACEUTICS

Gut microbiome, microbial metabolites and the development of NAFLD

(2018) Cyrielle Caussy et al.   Nature Reviews Gastroenterology & Hepatology

Microbial tryptophan catabolites in health and disease

(2018) Henrik M. Roager et al.   Nature Communications

Astaxanthin Prevents Alcoholic Fatty Liver Disease by Modulating Mouse Gut Microbiota

(2018) Huilin Liu et al.   Nutrients

Health benefits of Mediterranean diet in nonalcoholic fatty liver disease

(2018) Ludovico Abenavoli et al.   Expert Review of Gastroenterology & Hepatology

Mechanistic and therapeutic advances in non-alcoholic fatty liver disease by targeting the gut microbiota

(2018) Ruiting Han et al.   Frontiers of Medicine

The role of the microbiome in NAFLD and NASH

(2018) Aleksandra A Kolodziejczyk et al.   EMBO Molecular Medicine

SIRT3 Deficiency Promotes High-Fat Diet-Induced Nonalcoholic Fatty Liver Disease in Correlation with Impaired Intestinal Permeability through Gut Microbial Dysbiosis

(2018) Mengting Chen et al.   MOLECULAR NUTRITION & FOOD RESEARCH

The role of macrophages in nonalcoholic fatty liver disease and nonalcoholic steatohepatitis

(2018) Konstantin Kazankov et al.   Nature Reviews Gastroenterology & Hepatology

The gut microbiota in infants of obese mothers increases inflammation and susceptibility to NAFLD

(2018) Taylor K. Soderborg et al.   Nature Communications

Intestinal Microbiota Modulation in Obesity-Related Non-alcoholic Fatty Liver Disease

(2018) David Porras et al.   Frontiers in Physiology

Protective effect of quercetin on high-fat diet-induced non-alcoholic fatty liver disease in mice is mediated by modulating intestinal microbiota imbalance and related gut-liver axis activation

(2017) David Porras et al.   FREE RADICAL BIOLOGY AND MEDICINE

Bile Acid Control of Metabolism and Inflammation in Obesity, Type 2 Diabetes, Dyslipidemia, and Nonalcoholic Fatty Liver Disease

(2017) Oscar Chávez-Talavera et al.   GASTROENTEROLOGY

Targeting the gut microbiota with inulin-type fructans: preclinical demonstration of a novel approach in the management of endothelial dysfunction

(2017) Emilie Catry et al.   GUT

Adipose tissue macrophages induce hepatic neutrophil recruitment and macrophage accumulation in mice

(2017) Mitchell Bijnen et al.   GUT

Altered amino acid concentrations in NAFLD: Impact of obesity and insulin resistance

(2017) Melania Gaggini et al.   HEPATOLOGY

Treatment efficacy of a probiotic preparation for non-alcoholic steatohepatitis: A pilot trial

(2017) Elina Manzhalii et al.   Journal of Digestive Diseases

Treatment of NAFLD with diet, physical activity and exercise

(2017) Manuel Romero-Gómez et al.   JOURNAL OF HEPATOLOGY

Cause, Pathogenesis, and Treatment of Nonalcoholic Steatohepatitis

(2017) Anna M. Diehl et al.   NEW ENGLAND JOURNAL OF MEDICINE

A study of the prebiotic-like effects of tomato juice consumption in rats with diet-induced non-alcoholic fatty liver disease (NAFLD)

(2017) F. J. García-Alonso et al.   Food & Function

Nonalcoholic Fatty Liver Disease and Insulin Resistance: New Insights and Potential New Treatments

(2017) Hironori Kitade et al.   Nutrients

Gut Microbiota and Nonalcoholic Fatty Liver Disease: Insights on Mechanisms and Therapy

(2017) Junli Ma et al.   Nutrients

Multi-targeting therapeutic mechanisms of the Chinese herbal medicine QHD in the treatment of non-alcoholic fatty liver disease

(2017) Qin Feng et al.   Oncotarget

Balancing Herbal Medicine and Functional Food for Prevention and Treatment of Cardiometabolic Diseases through Modulating Gut Microbiota

(2017) Ming Lyu et al.   Frontiers in Microbiology

Fructo-oligosaccharides and intestinal barrier function in a methionine–choline-deficient mouse model of nonalcoholic steatohepatitis

(2017) Kotaro Matsumoto et al.   PLoS One

Total fecal microbiota transplantation alleviates high-fat diet-induced steatohepatitis in mice via beneficial regulation of gut microbiota

(2017) Da Zhou et al.   Scientific Reports

Gut microbiota are linked to increased susceptibility to hepatic steatosis in low-aerobic-capacity rats fed an acute high-fat diet

(2016) Matthew R. Panasevich et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Protective effects of Lactobacillus rhamnosus GG against dyslipidemia in high-fat diet-induced obese mice

(2016) Bobae Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Circadian Homeostasis of Liver Metabolism Suppresses Hepatocarcinogenesis

(2016) Nicole M. Kettner et al.   CANCER CELL

A Dietary Fiber-Deprived Gut Microbiota Degrades the Colonic Mucus Barrier and Enhances Pathogen Susceptibility

(2016) Mahesh S. Desai et al.   CELL

Altered Gut Microbiota Composition and Immune Response in Experimental Steatohepatitis Mouse Models

(2016) Mitsuaki Ishioka et al.   DIGESTIVE DISEASES AND SCIENCES

Loss of Junctional Adhesion Molecule A Promotes Severe Steatohepatitis in Mice on a Diet High in Saturated Fat, Fructose, and Cholesterol

(2016) Khalidur Rahman et al.   GASTROENTEROLOGY

Microbiota-induced obesity requires farnesoid X receptor

(2016) Ava Parséus et al.   GUT

Gut microbiota profiling of pediatric nonalcoholic fatty liver disease and obese patients unveiled by an integrated meta-omics-based approach

(2016) Federica Del Chierico et al.   HEPATOLOGY

The severity of nonalcoholic fatty liver disease is associated with gut dysbiosis and shift in the metabolic function of the gut microbiota

(2016) Jérôme Boursier et al.   HEPATOLOGY

Bile Acids Control Inflammation and Metabolic Disorder through Inhibition of NLRP3 Inflammasome

(2016) Chuansheng Guo et al.   IMMUNITY

Liver innate immune cells and insulin resistance: the multiple facets of Kupffer cells

(2016) J. Jager et al.   JOURNAL OF INTERNAL MEDICINE

Human gut microbes impact host serum metabolome and insulin sensitivity

(2016) Helle Krogh Pedersen et al.   NATURE

The role of the gut microbiota in NAFLD

(2016) Christopher Leung et al.   Nature Reviews Gastroenterology & Hepatology

A sentinel goblet cell guards the colonic crypt by triggering Nlrp6-dependent Muc2 secretion

(2016) G. M. H. Birchenough et al.   SCIENCE

Novel Action of Carotenoids on Non-Alcoholic Fatty Liver Disease: Macrophage Polarization and Liver Homeostasis

(2016) Yinhua Ni et al.   Nutrients

Beneficial Effect of Synbiotic Supplementation on Hepatic Steatosis and Anthropometric Parameters, But Not on Gut Permeability in a Population with Nonalcoholic Steatohepatitis

(2016) Silvia Ferolla et al.   Nutrients

Indigenous Bacteria from the Gut Microbiota Regulate Host Serotonin Biosynthesis

(2015) Jessica M. Yano et al.   CELL

FXR Agonists as Therapeutic Agents for Non-alcoholic Fatty Liver Disease

(2015) Rotonya M. Carr et al.   Current Atherosclerosis Reports

Prevention and Reversal of Lipotoxicity-Induced Hepatic Insulin Resistance and Steatohepatitis in Mice by an Antioxidant Carotenoid, β-Cryptoxanthin

(2015) Yinhua Ni et al.   ENDOCRINOLOGY

Intestinal farnesoid X receptor puts a fresh coat of wax on fatty liver

(2015) Iina Tuominen et al.   HEPATOLOGY

A novel cobiotic-based preventive approach against high-fat diet-induced adiposity, nonalcoholic fatty liver and gut derangement in mice

(2015) D P Singh et al.   INTERNATIONAL JOURNAL OF OBESITY

Blocking high-fat diet-induced obesity, insulin resistance and fatty liver by overexpression of Il-13 gene in mice

(2015) P Darkhal et al.   INTERNATIONAL JOURNAL OF OBESITY

Ganoderma lucidum reduces obesity in mice by modulating the composition of the gut microbiota

(2015) Chih-Jung Chang et al.   Nature Communications

Astaxanthin prevents and reverses diet-induced insulin resistance and steatohepatitis in mice: A comparison with vitamin E

(2015) Yinhua Ni et al.   Scientific Reports

Randomised clinical trial: the beneficial effects of VSL#3 in obese children with non-alcoholic steatohepatitis

(2014) A. Alisi et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Intrinsic aerobic capacity impacts susceptibility to acute high-fat diet-induced hepatic steatosis

(2014) E. Matthew Morris et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Exercise and associated dietary extremes impact on gut microbial diversity

(2014) Siobhan F Clarke et al.   GUT

Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines

(2014) Peter J. Murray et al.   IMMUNITY

Intestinal farnesoid X receptor signaling promotes nonalcoholic fatty liver disease

(2014) Changtao Jiang et al.   JOURNAL OF CLINICAL INVESTIGATION

Inhibiting peripheral serotonin synthesis reduces obesity and metabolic dysfunction by promoting brown adipose tissue thermogenesis

(2014) Justin D Crane et al.   NATURE MEDICINE

Glucokinase Regulatory Protein Gene Polymorphism Affects Liver Fibrosis in Non-Alcoholic Fatty Liver Disease

(2014) Salvatore Petta et al.   PLoS One

Lactobacillus rhamnosus GG Protects against Non-Alcoholic Fatty Liver Disease in Mice

(2014) Yvonne Ritze et al.   PLoS One

β-Cryptoxanthin Alleviates Diet-Induced Nonalcoholic Steatohepatitis by Suppressing Inflammatory Gene Expression in Mice

(2014) Masuko Kobori et al.   PLoS One

Effects of resveratrol on gut microbiota and fat storage in a mouse model with high-fat-induced obesity

(2014) Yi Qiao et al.   Food & Function

Vitamin E and changes in serum alanine aminotransferase levels in patients with non-alcoholic steatohepatitis

(2013) J. H. Hoofnagle et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Fecal Microbiome and Volatile Organic Compound Metabolome in Obese Humans With Nonalcoholic Fatty Liver Disease

(2013) Maitreyi Raman et al.   Clinical Gastroenterology and Hepatology

Both resistance training and aerobic training reduce hepatic fat content in type 2 diabetic subjects with nonalcoholic fatty liver disease (the RAED2 randomized trial)

(2013) Elisabetta Bacchi et al.   HEPATOLOGY

Endotoxemia unrequired in the pathogenesis of pediatric nonalcoholic steatohepatitis

(2013) Jianye Yuan et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome

(2013) Shin Yoshimoto et al.   NATURE

Disruption of the Circadian Clock in Mice Increases Intestinal Permeability and Promotes Alcohol-Induced Hepatic Pathology and Inflammation

(2013) Keith C. Summa et al.   PLoS One

Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity

(2013) A. Everard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Quercetin ameliorate insulin resistance and up-regulates cellular antioxidants during oleic acid induced hepatic steatosis in HepG2 cells

(2013) Satyakumar Vidyashankar et al.   TOXICOLOGY IN VITRO

Prospective histopathologic evaluation of lifestyle modification in nonalcoholic fatty liver disease: a randomized trial

(2013) Carly Eckard et al.   Therapeutic Advances in Gastroenterology

Hepatic recruitment of macrophages promotes nonalcoholic steatohepatitis through CCR2

(2012) Kouichi Miura et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Saturated fat stimulates obesity and hepatic steatosis and affects gut microbiota composition by an enhanced overflow of dietary fat to the distal intestine

(2012) Nicole de Wit et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Insight into the prebiotic concept: lessons from an exploratory, double blind intervention study with inulin-type fructans in obese women

(2012) Evelyne M Dewulf et al.   GUT

Intestinal microbiota determines development of non-alcoholic fatty liver disease in mice

(2012) Tiphaine Le Roy et al.   GUT

Characterization of gut microbiomes in nonalcoholic steatohepatitis (NASH) patients: A connection between endogenous alcohol and NASH

(2012) Lixin Zhu et al.   HEPATOLOGY

Toll-like receptor 2 and palmitic acid cooperatively contribute to the development of nonalcoholic steatohepatitis through inflammasome activation in mice

(2012) Kouichi Miura et al.   HEPATOLOGY

Quercetin Treatment Ameliorates Inflammation and Fibrosis in Mice with Nonalcoholic Steatohepatitis1–3

(2012) Eder Marcolin et al.   JOURNAL OF NUTRITION

The role of Kupffer cells in the morphogenesis of nonalcoholic steatohepatitis – ultrastructural findings. The first report in pediatric patients

(2012) Joanna Maria Lotowska et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

Bifidobacterium longum with Fructo-Oligosaccharides in Patients with Non Alcoholic Steatohepatitis

(2011) Michele Malaguarnera et al.   DIGESTIVE DISEASES AND SCIENCES

Vitamin D deficiency in obese rats exacerbates nonalcoholic fatty liver disease and increases hepatic resistin and toll-like receptor activation

(2011) Christian L. Roth et al.   HEPATOLOGY

Hepatic macrophage migration and differentiation critical for liver fibrosis is mediated by the chemokine receptor C-C motif chemokine receptor 8 in mice

(2011) Felix Heymann et al.   HEPATOLOGY

Supplementation with probiotics modifies gut flora and attenuates liver fat accumulation in rat nonalcoholic fatty liver disease model

(2011) Ren-ying Xu et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

DSS induced colitis increases portal LPS levels and enhances hepatic inflammation and fibrogenesis in experimental NASH

(2011) Erwin Gäbele et al.   JOURNAL OF HEPATOLOGY

Modulation of Mucosal Immune Response, Tolerance, and Proliferation in Mice Colonized by the Mucin-Degrader Akkermansia muciniphila

(2011) Muriel Derrien et al.   Frontiers in Microbiology

Hepatic lipotoxicity and the pathogenesis of nonalcoholic steatohepatitis: The central role of nontriglyceride fatty acid metabolites

(2010) Brent A. Neuschwander-Tetri   HEPATOLOGY

Reduction of lipid accumulation in HepG2 Cells by luteolin is associated with activation of AMPK and Mitigation of oxidative stress

(2010) Jin-Feng Liu et al.   PHYTOTHERAPY RESEARCH

VSL#3 probiotic treatment attenuates fibrosis without changes in steatohepatitis in a diet-induced nonalcoholic steatohepatitis model in mice

(2009) Arumugam Velayudham et al.   HEPATOLOGY

Indoleamine 2,3-dioxygenase in intestinal immunity and inflammation

(2009) Bobby J. Cherayil   INFLAMMATORY BOWEL DISEASES

The bacterial signal indole increases epithelial-cell tight-junction resistance and attenuates indicators of inflammation

(2009) T. Bansal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Expression and function of the bile acid receptor TGR5 in Kupffer cells

(2008) Verena Keitel et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Probiotics improve high fat diet-induced hepatic steatosis and insulin resistance by increasing hepatic NKT cells

(2008) Xiong Ma et al.   JOURNAL OF HEPATOLOGY