A sentinel goblet cell guards the colonic crypt by triggering Nlrp6-dependent Muc2 secretion
Published 2016 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
A sentinel goblet cell guards the colonic crypt by triggering Nlrp6-dependent Muc2 secretion
Authors
Keywords
-
Journal
SCIENCE
Volume 352, Issue 6293, Pages 1535-1542
Publisher
American Association for the Advancement of Science (AAAS)
Online
2016-06-25
DOI
10.1126/science.aaf7419
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- NLRP6 Inflammasome Orchestrates the Colonic Host-Microbial Interface by Regulating Goblet Cell Mucus Secretion
- (2014) Marta Wlodarska et al. CELL
- Mechanisms and Functions of Inflammasomes
- (2014) Mohamed Lamkanfi et al. CELL
- NADPH oxidases: an overview from structure to innate immunity-associated pathologies
- (2014) Arvind Panday et al. Cellular & Molecular Immunology
- The composition of the gut microbiota shapes the colon mucus barrier
- (2014) H. E. Jakobsson et al. EMBO REPORTS
- Caspase-11 is expressed in the colonic mucosa and protects against dextran sodium sulfate-induced colitis
- (2014) D Demon et al. Mucosal Immunology
- Microbial sensing by goblet cells controls immune surveillance of luminal antigens in the colon
- (2014) K A Knoop et al. Mucosal Immunology
- Autophagy proteins control goblet cell function by potentiating reactive oxygen species production
- (2013) Khushbu K Patel et al. EMBO JOURNAL
- Bacteria penetrate the normally impenetrable inner colon mucus layer in both murine colitis models and patients with ulcerative colitis
- (2013) Malin E V Johansson et al. GUT
- Targeted deletion of MyD88 in intestinal epithelial cells results in compromised antibacterial immunity associated with downregulation of polymeric immunoglobulin receptor, mucin-2 and antibacterial peptides
- (2012) A L Frantz et al. Mucosal Immunology
- Goblet cells deliver luminal antigen to CD103+ dendritic cells in the small intestine
- (2012) Jeremiah R. McDole et al. NATURE
- Fast Renewal of the Distal Colonic Mucus Layers by the Surface Goblet Cells as Measured by In Vivo Labeling of Mucin Glycoproteins
- (2012) Malin E. V. Johansson PLoS One
- Calcium and pH-dependent packing and release of the gel-forming MUC2 mucin
- (2012) D. Ambort et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- An ex vivo method for studying mucus formation, properties, and thickness in human colonic biopsies and mouse small and large intestinal explants
- (2011) Jenny K. Gustafsson et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- NLRP6 Inflammasome Regulates Colonic Microbial Ecology and Risk for Colitis
- (2011) Eran Elinav et al. CELL
- Cutting Edge: Reactive Oxygen Species Inhibitors Block Priming, but Not Activation, of the NLRP3 Inflammasome
- (2011) F. Bauernfeind et al. JOURNAL OF IMMUNOLOGY
- Bacteria Penetrate the Inner Mucus Layer before Inflammation in the Dextran Sulfate Colitis Model
- (2010) Malin E. V. Johansson et al. PLoS One
- Muc2 Protects against Lethal Infectious Colitis by Disassociating Pathogenic and Commensal Bacteria from the Colonic Mucosa
- (2010) Kirk S. B. Bergstrom et al. PLoS Pathogens
- Thioredoxin-interacting protein links oxidative stress to inflammasome activation
- (2009) Rongbin Zhou et al. NATURE IMMUNOLOGY
- The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria
- (2008) M. E. V. Johansson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now