Cancer stem cells, epigenetics, tumor microenvironment and future therapeutics in cutaneous malignant melanoma: a review
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Cancer stem cells, epigenetics, tumor microenvironment and future therapeutics in cutaneous malignant melanoma: a review
Authors
Keywords
-
Journal
Future Oncology
Volume 16, Issue 21, Pages 1549-1567
Publisher
Future Medicine Ltd
Online
2020-06-02
DOI
10.2217/fon-2020-0151
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Cancer Stem Cells: The Architects of the Tumor Ecosystem
- (2019) Briana C. Prager et al. Cell Stem Cell
- Role of miRNAs in Melanoma Metastasis
- (2019) Anna Gajos-Michniewicz et al. Cancers
- Emerging roles of H3K9me3, SETDB1 and SETDB2 in therapy-induced cellular reprogramming
- (2019) Joachim Torrano et al. Clinical Epigenetics
- UTX Mutations in Human Cancer
- (2019) Lu Wang et al. CANCER CELL
- Network Medicine in Pathobiology
- (2019) Laurel Yong-Hwa Lee et al. AMERICAN JOURNAL OF PATHOLOGY
- Histone methyltransferase SETDB1 contributes to melanoma tumorigenesis and serves as a new potential therapeutic target
- (2019) Elias Orouji et al. INTERNATIONAL JOURNAL OF CANCER
- Characterization of mechano-microenvironment of acral melanoma and its potential impact on tumor cell invasion.
- (2019) Xin Yi et al. JOURNAL OF CLINICAL ONCOLOGY
- Targeting DNA Methylation and EZH2 Activity to Overcome Melanoma Resistance to Immunotherapy
- (2019) Abdullah Al Emran et al. TRENDS IN IMMUNOLOGY
- Prognostic value of B cells in cutaneous melanoma
- (2019) Sara R. Selitsky et al. Genome Medicine
- Epigenetics in cancer therapy and nanomedicine
- (2019) Annalisa Roberti et al. Clinical Epigenetics
- Understanding heterogeneous tumor microenvironment in metastatic melanoma
- (2019) Yiyi Yan et al. PLoS One
- Cellular and molecular biology of cancer stem cells in melanoma: Possible therapeutic implications
- (2019) Monica Marzagalli et al. SEMINARS IN CANCER BIOLOGY
- A novel germline variant in the DOT1L gene co-segregating in a Dutch family with a history of melanoma
- (2019) Catarina Salgado et al. MELANOMA RESEARCH
- Unraveling the crosstalk between melanoma and immune cells in the tumor microenvironment
- (2019) Monica Marzagalli et al. SEMINARS IN CANCER BIOLOGY
- Cancer cell reprogramming: a promising therapy converting malignancy to benignity
- (2019) Lanqi Gong et al. Cancer Communications
- B cells sustain inflammation and predict response to immune checkpoint blockade in human melanoma
- (2019) Johannes Griss et al. Nature Communications
- Immunobiology of Uveal Melanoma: State of the Art and Therapeutic Targets
- (2019) Maria Sofia Basile et al. Frontiers in Oncology
- Epithelial-Mesenchymal Transition in Skin Cancers: A Review
- (2019) Anastasia Hodorogea et al. Analytical Cellular Pathology
- Subcutaneous injection of multipotent mesenchymal stromal cells admixed with melanoma cells in mice favors tumor incidence and growth: a systematic review and meta-analysis
- (2018) Marcos Freitas Cordeiro et al. ARCHIVES OF DERMATOLOGICAL RESEARCH
- Targeting the Senescence-Overriding Cooperative Activity of Structurally Unrelated H3K9 Demethylases in Melanoma
- (2018) Yong Yu et al. CANCER CELL
- EZH2-Mediated Primary Cilium Deconstruction Drives Metastatic Melanoma Formation
- (2018) Daniel Zingg et al. CANCER CELL
- Targeting the tumour stroma to improve cancer therapy
- (2018) Kenneth C. Valkenburg et al. Nature Reviews Clinical Oncology
- Regulation of melanocyte stem cell behavior by the niche microenvironment
- (2018) Huirong Li et al. Pigment Cell & Melanoma Research
- Melanoma and Immune Checkpoint Inhibitors
- (2018) Masutaka Furue et al. Current Oncology Reports
- The protective role of DOT1L in UV-induced melanomagenesis
- (2018) Bo Zhu et al. Nature Communications
- Targeting melanoma stem cells with the Vitamin E derivative δ-tocotrienol
- (2018) Monica Marzagalli et al. Scientific Reports
- Microenvironment-Driven Dynamic Heterogeneity and Phenotypic Plasticity as a Mechanism of Melanoma Therapy Resistance
- (2018) Farzana Ahmed et al. Frontiers in Oncology
- Personalized Medicine in Malignant Melanoma: Towards Patient Tailored Treatment
- (2018) Hildur Helgadottir et al. Frontiers in Oncology
- Melanoma treatment: from conventional to nanotechnology
- (2018) Harshita Mishra et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- Regulation of the adaptation to ER stress by KLF4 facilitates melanoma cell metastasis via upregulating NUCB2 expression
- (2018) Dongmei Zhang et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- B cells and antibody production in melanoma
- (2018) Jessica Da Gama Duarte et al. MAMMALIAN GENOME
- Bad Company: Microenvironmentally Mediated Resistance to Targeted Therapy in Melanoma
- (2018) Filipe V Almeida et al. Pigment Cell & Melanoma Research
- Overview of advances in vasculogenic mimicry – a potential target for tumor therapy
- (2018) Hong Ge et al. Cancer Management and Research
- Clinical epigenetics: seizing opportunities for translation
- (2018) María Berdasco et al. NATURE REVIEWS GENETICS
- Tackling malignant melanoma epigenetically: histone lysine methylation
- (2018) Elias Orouji et al. Clinical Epigenetics
- Expression of cancer stem cell markers in metastatic melanoma to the brain
- (2018) Agadha C. Wickremesekera et al. JOURNAL OF CLINICAL NEUROSCIENCE
- PD-L1 expression in tumor metastasis is different between uveal melanoma and cutaneous melanoma
- (2017) Asad Javed et al. Immunotherapy
- Primary and acquired resistance to PD-1/PD-L1 blockade in cancer treatment
- (2017) Qiaohong Wang et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- miRNAs, Melanoma and Microenvironment: An Intricate Network
- (2017) Gabriele Romano et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Cancer Stem Cells (CSCs) in melanoma: There's smoke, but is there fire?
- (2017) Constance E. Brinckerhoff JOURNAL OF CELLULAR PHYSIOLOGY
- The use of immunotherapy in the treatment of melanoma
- (2017) Tala Achkar et al. Journal of Hematology & Oncology
- The new paradigm of systemic therapies for metastatic melanoma
- (2017) Virginia O. Volpe et al. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
- Melanoma subtypes demonstrate distinct PD-L1 expression profiles
- (2017) Genevieve J Kaunitz et al. LABORATORY INVESTIGATION
- Notch3 signaling-mediated melanoma–endothelial crosstalk regulates melanoma stem-like cell homeostasis and niche morphogenesis
- (2017) Mei-Yu Hsu et al. LABORATORY INVESTIGATION
- Mesenchymal stem cells induce epithelial mesenchymal transition in melanoma by paracrine secretion of transforming growth factor-β
- (2017) Chuan Lv et al. MELANOMA RESEARCH
- Therapeutic implications of cellular and molecular biology of cancer stem cells in melanoma
- (2017) Dhiraj Kumar et al. Molecular Cancer
- Sox2 is not required for melanomagenesis, melanoma growth and melanoma metastasis in vivo
- (2017) V Cesarini et al. ONCOGENE
- Sox2 is dispensable for primary melanoma and metastasis formation
- (2017) S M Schaefer et al. ONCOGENE
- KLF4 is regulated by RAS/RAF/MEK/ERK signaling through E2F1 and promotes melanoma cell growth
- (2017) M Riverso et al. ONCOGENE
- Metabolic strategies of melanoma cells: Mechanisms, interactions with the tumor microenvironment, and therapeutic implications
- (2017) Grant M. Fischer et al. Pigment Cell & Melanoma Research
- Epigenetics of malignant melanoma
- (2017) Bruce Moran et al. SEMINARS IN CANCER BIOLOGY
- Novel Opportunities to Use Radiation Therapy with Immune Checkpoint Inhibitors for Melanoma Management
- (2017) Kamran A. Ahmed et al. Surgical Oncology Clinics of North America
- Tumor-associated B-cells induce tumor heterogeneity and therapy resistance
- (2017) Rajasekharan Somasundaram et al. Nature Communications
- Microenvironment-derived factors driving metastatic plasticity in melanoma
- (2017) Isabella S. Kim et al. Nature Communications
- DNA methylation/hydroxymethylation in melanoma
- (2017) Siqi Fu et al. Oncotarget
- Melanoma-associated fibroblasts decrease tumor cell susceptibility to NK cell-mediated killing through matrix-metalloproteinases secretion
- (2017) Linda Ziani et al. Oncotarget
- MicroRNAs in melanoma development and resistance to target therapy
- (2017) Luigi Fattore et al. Oncotarget
- Aberrant DNA methylation in melanoma: biomarker and therapeutic opportunities
- (2017) Goran Micevic et al. Clinical Epigenetics
- B cells and the humoral response in melanoma: The overlooked players of the tumor microenvironment
- (2017) Giulia Chiaruttini et al. OncoImmunology
- Epigenetics in Human Melanoma
- (2017) Paul M. Howell et al. Cancer Control
- Epithelial–Mesenchymal Expression Phenotype of Primary Melanoma and Matched Metastases and Relationship with Overall Survival
- (2016) SHAOFENG YAN et al. ANTICANCER RESEARCH
- Role of EZH2 histone methyltrasferase in melanoma progression and metastasis
- (2016) Fade Mahmoud et al. CANCER BIOLOGY & THERAPY
- H3K27 Demethylase JMJD3 Employs the NF- B and BMP Signaling Pathways to Modulate the Tumor Microenvironment and Promote Melanoma Progression and Metastasis
- (2016) W.-Y. Park et al. CANCER RESEARCH
- Usefulness of serum 5-S-cysteinyl-dopa as a biomarker for predicting prognosis and detecting relapse in patients with advanced stage malignant melanoma
- (2016) Hiroshi Umemura et al. JOURNAL OF DERMATOLOGY
- Promoter Methylation of PTEN Is a Significant Prognostic Factor in Melanoma Survival
- (2016) Mi Ryung Roh et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Notch1-MAPK Signaling Axis Regulates CD133 + Cancer Stem Cell-Mediated Melanoma Growth and Angiogenesis
- (2016) Dhiraj Kumar et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- C-myc overexpression drives melanoma metastasis by promoting vasculogenic mimicry via c-myc/snail/Bax signaling
- (2016) Xian Lin et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Cancer stem cells
- (2016) Jeremy N. Rich MEDICINE
- Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq
- (2016) I. Tirosh et al. SCIENCE
- Lunasin is a novel therapeutic agent for targeting melanoma cancer stem cells
- (2016) Chris Shidal et al. Oncotarget
- Etoposide-Bevacizumab a new strategy against human melanoma cells expressing stem-like traits
- (2016) Maura Calvani et al. Oncotarget
- Inactivation of the CRL4-CDT2-SET8/p21 ubiquitylation and degradation axis underlies the therapeutic efficacy of pevonedistat in melanoma
- (2016) Mouadh Benamar et al. EBioMedicine
- Epigenetic Modifications in Cutaneous Malignant Melanoma
- (2015) Panagiotis Kampilafkos et al. AMERICAN JOURNAL OF DERMATOPATHOLOGY
- Epigenetic regulation in human melanoma: past and future
- (2015) Debina Sarkar et al. Epigenetics
- Erratum: Osteopontin signaling upregulates cyclooxygenase-2 expression in tumor-associated macrophages leading to enhanced angiogenesis and melanoma growth via α9β1 integrin
- (2015) S Kale et al. ONCOGENE
- The epigenetic modifier EZH2 controls melanoma growth and metastasis through silencing of distinct tumour suppressors
- (2015) Daniel Zingg et al. Nature Communications
- Dual Roles of RNF2 in Melanoma Progression
- (2015) K. Rai et al. Cancer Discovery
- Epigenetic reprogramming by tumor-derived EZH2 gain-of-function mutations promotes aggressive 3D cell morphologies and enhances melanoma tumor growth
- (2015) Anthony M. Barsotti et al. Oncotarget
- Antagonistic Cross-Regulation between Sox9 and Sox10 Controls an Anti-tumorigenic Program in Melanoma
- (2015) Olga Shakhova et al. PLoS Genetics
- Epigenetic treatment of solid tumours: a review of clinical trials
- (2015) Clara Nervi et al. Clinical Epigenetics
- Phenotype Switching in Melanoma: Implications for Progression and Therapy
- (2015) Frederic Zhentao Li et al. Frontiers in Oncology
- Genetic and epigenetic loss of microRNA-31 leads to feed-forward expression of EZH2 in melanoma
- (2015) Irfan A Asangani et al. Oncotarget
- Treatment of resistant metastatic melanoma using sequential epigenetic therapy (decitabine and panobinostat) combined with chemotherapy (temozolomide)
- (2014) Chang Xia et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Melanoma epigenetics: novel mechanisms, markers and medicines
- (2014) Jonathan J Lee et al. LABORATORY INVESTIGATION
- Combined BRAF and MEK Inhibition versus BRAF Inhibition Alone in Melanoma
- (2014) Georgina V. Long et al. NEW ENGLAND JOURNAL OF MEDICINE
- SOX2 regulates self-renewal and tumorigenicity of human melanoma-initiating cells
- (2014) R Santini et al. ONCOGENE
- EZH2: an emerging role in melanoma biology and strategies for targeted therapy
- (2014) Jessamy Tiffen et al. Pigment Cell & Melanoma Research
- The Nerve Growth Factor Receptor CD271 Is Crucial to Maintain Tumorigenicity and Stem-Like Properties of Melanoma Cells
- (2014) Torben Redmer et al. PLoS One
- Expression of proteins involved in epigenetic regulation in human cutaneous melanoma and peritumoral skin
- (2014) Anatoly Uzdensky et al. TUMOR BIOLOGY
- Epigenetics of human melanoma: promises and challenges
- (2014) A. Besaratinia et al. Journal of Molecular Cell Biology
- Overcoming Intrinsic Multidrug Resistance in Melanoma by Blocking the Mitochondrial Respiratory Chain of Slow-Cycling JARID1Bhigh Cells
- (2013) Alexander Roesch et al. CANCER CELL
- Functional features of cancer stem cells in melanoma cell lines
- (2013) Rüdiger M Zimmerer et al. Cancer Cell International
- Epigenome-wide DNA methylation landscape of melanoma progression to brain metastasis reveals aberrations on homeobox D cluster associated with prognosis
- (2013) Diego M. Marzese et al. HUMAN MOLECULAR GENETICS
- HIF1α and HIF2α independently activate SRC to promote melanoma metastases
- (2013) Sara C. Hanna et al. JOURNAL OF CLINICAL INVESTIGATION
- Melanoma stem cells and metastasis: mimicking hematopoietic cell trafficking?
- (2013) Nayoung Lee et al. LABORATORY INVESTIGATION
- The antimelanoma activity of the histone deacetylase inhibitor panobinostat (LBH589) is mediated by direct tumor cytotoxicity and increased tumor immunogenicity
- (2013) David M. Woods et al. MELANOMA RESEARCH
- Stem cells and targeted approaches to melanoma cure
- (2013) George F. Murphy et al. MOLECULAR ASPECTS OF MEDICINE
- TET enzymes, TDG and the dynamics of DNA demethylation
- (2013) Rahul M. Kohli et al. NATURE
- miR in melanoma development: miRNAs and acquired hallmarks of cancer in melanoma
- (2013) Paige E. Bennett et al. PHYSIOLOGICAL GENOMICS
- Functional Characterization of Stromal Osteopontin in Melanoma Progression and Metastasis
- (2013) Santosh Kumar et al. PLoS One
- Markers of circulating tumour cells in the peripheral blood of patients with melanoma correlate with disease recurrence and progression
- (2012) A.L. Reid et al. BRITISH JOURNAL OF DERMATOLOGY
- Epigenetic biomarkers in skin cancer
- (2012) Edward S. Greenberg et al. CANCER LETTERS
- A Landscape of Driver Mutations in Melanoma
- (2012) Eran Hodis et al. CELL
- Nanog and Oct4 overexpression increases motility and transmigration of melanoma cells
- (2012) Aurelie Borrull et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- Microenvironment and tumor progression of melanoma: New therapeutic prospectives
- (2012) Gerardo Botti et al. Journal of Immunotoxicology
- Melanoma genome sequencing reveals frequent PREX2 mutations
- (2012) Michael F. Berger et al. NATURE
- Sox10 promotes the formation and maintenance of giant congenital naevi and melanoma
- (2012) Olga Shakhova et al. NATURE CELL BIOLOGY
- Mining Gene Expression Signature for the Detection of Pre-Malignant Melanocytes and Early Melanomas with Risk for Metastasis
- (2012) Camila Ferreira de Souza et al. PLoS One
- ALDH1A Isozymes are Markers of Human Melanoma Stem Cells and Potential Therapeutic Targets
- (2012) Yuchun Luo et al. STEM CELLS
- VEGFR-1 Expressed by Malignant Melanoma-Initiating Cells Is Required for Tumor Growth
- (2011) Natasha Y. Frank et al. CANCER RESEARCH
- Human CD271-Positive Melanoma Stem Cells Associated with Metastasis Establish Tumor Heterogeneity and Long-term Growth
- (2011) G. Civenni et al. CANCER RESEARCH
- RANK Is Expressed in Metastatic Melanoma and Highly Upregulated on Melanoma-Initiating Cells
- (2011) Verena Kupas et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Melanoma stem cells: not rare, but well done
- (2011) Sasha D Girouard et al. LABORATORY INVESTIGATION
- EZH2-Dependent Suppression of a Cellular Senescence Phenotype in Melanoma Cells by Inhibition of p21/CDKN1A Expression
- (2011) T. Fan et al. MOLECULAR CANCER RESEARCH
- The histone methyltransferase SETDB1 is recurrently amplified in melanoma and accelerates its onset
- (2011) Craig J. Ceol et al. NATURE
- ABCB1 identifies a subpopulation of uveal melanoma cells with high metastatic propensity
- (2011) Solange Landreville et al. Pigment Cell & Melanoma Research
- Isolation of tumorigenic circulating melanoma cells
- (2010) Jie Ma et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Phenotypic Heterogeneity among Tumorigenic Melanoma Cells from Patients that Is Reversible and Not Hierarchically Organized
- (2010) Elsa Quintana et al. CANCER CELL
- Modulation of T-Cell Activation by Malignant Melanoma Initiating Cells
- (2010) T. Schatton et al. CANCER RESEARCH
- A Temporarily Distinct Subpopulation of Slow-Cycling Melanoma Cells Is Required for Continuous Tumor Growth
- (2010) Alexander Roesch et al. CELL
- Selection of Tumorigenic Melanoma Cells Using ALDH
- (2010) Jim B. Boonyaratanakornkit et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Heterogeneous Phenotype of Human Melanoma Cells with In Vitro and In Vivo Features of Tumor-Initiating Cells
- (2010) Michela Perego et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- The In Vitro Spheroid Melanoma Cell Culture Assay: Cues on Tumor Initiation?
- (2010) Tobias Schatton et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Epigenetics of human cutaneous melanoma: setting the stage for new therapeutic strategies
- (2010) Luca Sigalotti et al. Journal of Translational Medicine
- Aberrant DNA methylation in malignant melanoma
- (2010) Carolina Schinke et al. MELANOMA RESEARCH
- Human melanoma-initiating cells express neural crest nerve growth factor receptor CD271
- (2010) Alexander D. Boiko et al. NATURE
- Tenascin-C promotes melanoma progression by maintaining the ABCB5-positive side population
- (2010) M Fukunaga-Kalabis et al. ONCOGENE
- Human malignant melanoma harbours a large fraction of highly clonogenic cells that do not express markers associated with cancer stem cells
- (2010) Lina Prasmickaite et al. Pigment Cell & Melanoma Research
- CXCR6, a Newly Defined Biomarker of Tissue-Specific Stem Cell Asymmetric Self-Renewal, Identifies More Aggressive Human Melanoma Cancer Stem Cells
- (2010) Rouzbeh Taghizadeh et al. PLoS One
- Expression of The Embryonic Stem Cell Transcription Factor SOX2 in Human Skin
- (2009) Alvaro C. Laga et al. AMERICAN JOURNAL OF PATHOLOGY
- Antitumor Immunity and Cancer Stem Cells
- (2009) Tobias Schatton et al. Annals of the New York Academy of Sciences
- Cancer stem cells sustaining the growth of mouse melanoma are not rare
- (2009) Yong Zhong et al. CANCER LETTERS
- CpG Island Methylator Phenotype Predicts Progression of Malignant Melanoma
- (2009) A. Tanemura et al. CLINICAL CANCER RESEARCH
- Multicenter phase II trial of the histone deacetylase inhibitor pyridylmethyl-N-{4-[(2-aminophenyl)-carbamoyl]-benzyl}-carbamate in pretreated metastatic melanoma
- (2009) Axel Hauschild et al. MELANOMA RESEARCH
- Molecular Pathways Mediating Liver Metastasis in Patients with Uveal Melanoma
- (2008) S. Bakalian et al. CLINICAL CANCER RESEARCH
- Identification of cells initiating human melanomas
- (2008) Tobias Schatton et al. NATURE
- Efficient tumour formation by single human melanoma cells
- (2008) Elsa Quintana et al. NATURE
- Melanoma and the tumor microenvironment
- (2008) Jessie Villanueva et al. Current Oncology Reports
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now