Epigenetics in Human Melanoma

New sulfurated derivatives of valproic acid with enhanced histone deacetylase inhibitory activity

(2008) Elena Perrino et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

The gene expression profiles of primary and metastatic melanoma yields a transition point of tumor progression and metastasis

(2008) Adam I Riker et al.   BMC Medical Genomics

Histone deacetylase inhibitors: Mechanisms of cell death and promise in combination cancer therapy

(2008) Jennifer S. Carew et al.   CANCER LETTERS

Microphthalmia-Associated Transcription Factor Is a Critical Transcriptional Regulator of Melanoma Inhibitor of Apoptosis in Melanomas

(2008) J. N. Dynek et al.   CANCER RESEARCH

MicroRNA-137 Targets Microphthalmia-Associated Transcription Factor in Melanoma Cell Lines

(2008) L. T. Bemis et al.   CANCER RESEARCH

The Promyelocytic Leukemia Zinc Finger-MicroRNA-221/-222 Pathway Controls Melanoma Progression through Multiple Oncogenic Mechanisms

(2008) F. Felicetti et al.   CANCER RESEARCH

Role of ING4 in human melanoma cell migration, invasion and patient survival

(2008) Jun Li et al.   CARCINOGENESIS

MicroRNA let-7b targets important cell cycle molecules in malignant melanoma cells and interferes with anchorage-independent growth

(2008) Julia Schultz et al.   CELL RESEARCH

A Phase I and Pharmacokinetic Study of the Oral Histone Deacetylase Inhibitor, MS-275, in Patients with Refractory Solid Tumors and Lymphomas

(2008) L. Gore et al.   CLINICAL CANCER RESEARCH

Isoform-Selective Histone Deacetylase Inhibitors

(2008) Takayoshi Suzuki et al.   CURRENT PHARMACEUTICAL DESIGN

The genetics of malignant melanoma

(2008) Jesus Lomas   Frontiers in Bioscience-Landmark

Identification of candidate tumor suppressor genes inactivated by promoter methylation in melanoma

(2008) Vanessa F. Bonazzi et al.   GENES CHROMOSOMES & CANCER

Transcriptional Modulation Using HDACi Depsipeptide Promotes Immune Cell-Mediated Tumor Destruction of Murine B16 Melanoma

(2008) Takashi Murakami et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Histone Deacetylase Inhibitors: From Bench to Clinic

(2008) Marielle Paris et al.   JOURNAL OF MEDICINAL CHEMISTRY

Trithiocarbonates as a Novel Class of HDAC Inhibitors: SAR Studies, Isoenzyme Selectivity, and Pharmacological Profiles

(2008) Florian Dehmel et al.   JOURNAL OF MEDICINAL CHEMISTRY

Total Synthesis and Biological Mode of Action of Largazole: A Potent Class I Histone Deacetylase Inhibitor

(2008) Albert Bowers et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Histone Deacetylase Inhibitor Depsipeptide Activates Silenced Genes through Decreasing both CpG and H3K9 Methylation on the Promoter

(2008) L.-P. Wu et al.   MOLECULAR AND CELLULAR BIOLOGY

Histone tail modifications and noncanonical functions of histones: perspectives in cancer epigenetics

(2008) A. Hadnagy et al.   MOLECULAR CANCER THERAPEUTICS

MicroRNA-10a Binds the 5′UTR of Ribosomal Protein mRNAs and Enhances Their Translation

(2008) Ulf Andersson Ørom et al.   MOLECULAR CELL

Chromatin-remodelling mechanisms in cancer

(2008) Laura Lafon-Hughes et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Epigenetic interplay between histone modifications and DNA methylation in gene silencing

(2008) T VAISSIERE et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

C-MYC overexpression is required for continuous suppression of oncogene-induced senescence in melanoma cells

(2008) D Zhuang et al.   ONCOGENE

Integrin β3 expression is regulated by let-7a miRNA in malignant melanoma

(2008) D W Müller et al.   ONCOGENE

HLA antigen changes in malignant cells: epigenetic mechanisms and biologic significance

(2008) M Campoli et al.   ONCOGENE

Pharmacologic suppression of MITF expression via HDAC inhibitors in the melanocyte lineage

(2008) Satoru Yokoyama et al.   Pigment Cell & Melanoma Research

Identification of novel epigenetically modified genes in human melanoma via promoter methylation gene profiling

(2008) Suhu Liu et al.   Pigment Cell & Melanoma Research

Changes in miRNA expression in solid tumors: An miRNA profiling in melanomas

(2008) Viktor Molnár et al.   SEMINARS IN CANCER BIOLOGY

A pervasive role of histone acetyltransferases and deacetylases in an NF-κB-signaling code

(2008) Miriam Calao et al.   TRENDS IN BIOCHEMICAL SCIENCES

Regulation of protein turnover by acetyltransferases and deacetylases

(2007) Karin Sadoul et al.   BIOCHIMIE

Dipeptidyl peptidase IV (DPPIV), a candidate tumor suppressor gene in melanomas is silenced by promoter methylation

(2007) Carolyn McGuinness   Frontiers in Bioscience-Landmark