Epigenetics of human melanoma: promises and challenges

Interplay between the Cancer Genome and Epigenome

(2013) Hui Shen et al.   CELL

New developments in biomarkers for melanoma

(2013) Klaus G. Griewank et al.   CURRENT OPINION IN ONCOLOGY

Alterations of DNA methylome in human bladder cancer

(2013) Ahmad Besaratinia et al.   Epigenetics

Melanoma genotypes and phenotypes get personal

(2013) Jose M Pimiento et al.   LABORATORY INVESTIGATION

The future of epigenetic therapy in solid tumours—lessons from the past

(2013) Nilofer Azad et al.   Nature Reviews Clinical Oncology

Epigenetic Hierarchy within the MAGEA1 Cancer-Germline Gene: Promoter DNA Methylation Dictates Local Histone Modifications

(2013) Julie Cannuyer et al.   PLoS One

Melanoma and Epigenetic Treatment: Past and Future

(2012) Caterina AM La Porta   Anti-Cancer Agents in Medicinal Chemistry

DNA Methylation Screening Identifies Driver Epigenetic Events of Cancer Cell Survival

(2012) Daniel D. De Carvalho et al.   CANCER CELL

Loss of 5-Hydroxymethylcytosine Is an Epigenetic Hallmark of Melanoma

(2012) Christine Guo Lian et al.   CELL

Cancer Epigenetics: From Mechanism to Therapy

(2012) Mark A. Dawson et al.   CELL

Update on the Current State of Melanoma Incidence

(2012) Emily G. Little et al.   DERMATOLOGIC CLINICS

Current limitations and future opportunities for epigenetic therapies

(2012) F Cherblanc et al.   Future Medicinal Chemistry

Melanoma: from mutations to medicine

(2012) H. Tsao et al.   GENES & DEVELOPMENT

Whole genome methylation profiles as independent markers of survival in stage IIIC melanoma patients

(2012) Luca Sigalotti et al.   Journal of Translational Medicine

Functions of DNA methylation: islands, start sites, gene bodies and beyond

(2012) Peter A. Jones   NATURE REVIEWS GENETICS

DNMT1 modulates gene expression without its catalytic activity partially through its interactions with histone-modifying enzymes

(2012) Eriko G. Clements et al.   NUCLEIC ACIDS RESEARCH

Emerging Epigenetic Targets and Therapies in Cancer Medicine

(2012) Relja Popovic et al.   Cancer Discovery

Chatting histone modifications in mammals

(2011) A. Izzo et al.   Briefings in Functional Genomics

Detection of Bladder Cancer Using Novel DNA Methylation Biomarkers in Urine Sediments

(2011) W. Chung et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Cancer epigenetics: linking basic biology to clinical medicine

(2011) Hsing-Chen Tsai et al.   CELL RESEARCH

Epigenetic reprogramming as a key contributor to melanocyte malignant transformation

(2011) Fernanda Molognoni et al.   Epigenetics

CpG islands and the regulation of transcription

(2011) A. M. Deaton et al.   GENES & DEVELOPMENT

Prognostic molecular biomarkers for cutaneous malignant melanoma

(2011) Ryo Tanaka et al.   JOURNAL OF SURGICAL ONCOLOGY

Increased methylation variation in epigenetic domains across cancer types

(2011) Kasper Daniel Hansen et al.   NATURE GENETICS

Cancer epigenetics reaches mainstream oncology

(2011) Manuel Rodríguez-Paredes et al.   NATURE MEDICINE

DNA-methylation profiling distinguishes malignant melanomas from benign nevi

(2011) Kathleen Conway et al.   Pigment Cell & Melanoma Research

Clinical outcome and pathological features associated with NRAS mutation in cutaneous melanoma

(2011) Bianca Devitt et al.   Pigment Cell & Melanoma Research

Unique DNA Methylation Patterns Distinguish Noninvasive and Invasive Urothelial Cancers and Establish an Epigenetic Field Defect in Premalignant Tissue

(2010) E. M. Wolff et al.   CANCER RESEARCH

HDAC4 inhibits the transcriptional activation of mda-7/IL-24 induced by Sp1

(2010) Lina Pan et al.   Cellular & Molecular Immunology

A new era: melanoma genetics and therapeutics

(2010) Justin M Ko et al.   JOURNAL OF PATHOLOGY

Epigenetics of human cutaneous melanoma: setting the stage for new therapeutic strategies

(2010) Luca Sigalotti et al.   Journal of Translational Medicine

CpG islands influence chromatin structure via the CpG-binding protein Cfp1

(2010) John P. Thomson et al.   NATURE

Conserved role of intragenic DNA methylation in regulating alternative promoters

(2010) Alika K. Maunakea et al.   NATURE

Epigenetic modifications as therapeutic targets

(2010) Theresa K Kelly et al.   NATURE BIOTECHNOLOGY

Epigenetic modifications and human disease

(2010) Anna Portela et al.   NATURE BIOTECHNOLOGY

Charting histone modifications and the functional organization of mammalian genomes

(2010) Vicky W. Zhou et al.   NATURE REVIEWS GENETICS

Principles and challenges of genome-wide DNA methylation analysis

(2010) Peter W. Laird   NATURE REVIEWS GENETICS

Targeting DNA methylation for epigenetic therapy

(2010) Xiaojing Yang et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

How Sunlight Causes Melanoma

(2010) Lilit Garibyan et al.   Current Oncology Reports

CpG Island Methylator Phenotype Predicts Progression of Malignant Melanoma

(2009) A. Tanemura et al.   CLINICAL CANCER RESEARCH

CpG island methylation profiling in human melanoma cell lines

(2009) Carmen S. Tellez et al.   MELANOMA RESEARCH

Differential methylation of tissue- and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts

(2009) Akiko Doi et al.   NATURE GENETICS

The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores

(2009) Rafael A Irizarry et al.   NATURE GENETICS

BrafV600E cooperates with Pten loss to induce metastatic melanoma

(2009) David Dankort et al.   NATURE GENETICS

Rethinking how DNA methylation patterns are maintained

(2009) Peter A. Jones et al.   NATURE REVIEWS GENETICS

Impaired recruitment of the histone methyltransferase DOT1L contributes to the incomplete reactivation of tumor suppressor genes upon DNA demethylation

(2009) F V Jacinto et al.   ONCOGENE

Epigenetic mechanisms in glioblastoma multiforme

(2009) Raman P. Nagarajan et al.   SEMINARS IN CANCER BIOLOGY

DNA hypomethylation in cancer cells

(2009) Melanie Ehrlich   Epigenomics

Tackling the methylome: recent methodological advances in genome-wide methylation profiling

(2009) Marcos RH Estécio et al.   Genome Medicine

Rapid repair of UVA-induced oxidized purines and persistence of UVB-induced dipyrimidine lesions determine the mutagenicity of sunlight in mouse cells

(2008) Ahmad Besaratinia et al.   FASEB JOURNAL

Sunlight ultraviolet irradiation andBRAFV600 mutagenesis in human melanoma

(2008) Ahmad Besaratinia et al.   HUMAN MUTATION

DNA methylomes, histone codes and miRNAs: Tying it all together

(2008) Sònia Guil et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Gene silencing in cancer by histone H3 lysine 27 trimethylation independent of promoter DNA methylation

(2008) Yutaka Kondo et al.   NATURE GENETICS

Genome-wide approaches to studying chromatin modifications

(2008) Dustin E. Schones et al.   NATURE REVIEWS GENETICS

DNA methylation landscapes: provocative insights from epigenomics

(2008) Miho M. Suzuki et al.   NATURE REVIEWS GENETICS

Epigenetics in Cancer

(2008) Manel Esteller   NEW ENGLAND JOURNAL OF MEDICINE

A Novel CpG Island Set Identifies Tissue-Specific Methylation at Developmental Gene Loci

(2008) Robert Illingworth et al.   PLOS BIOLOGY

Cancer Epigenetics: Modifications, Screening, and Therapy

(2007) Gal-Yam Einav Nili et al.   Annual Review of Medicine