Targeting mitochondrial fusion and fission proteins for cardioprotection
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Title
Targeting mitochondrial fusion and fission proteins for cardioprotection
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Journal
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
Volume -, Issue -, Pages -
Publisher
Wiley
Online
2020-05-14
DOI
10.1111/jcmm.15384
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Note: Only part of the references are listed.- Increased Drp1 Acetylation by Lipid Overload Induces Cardiomyocyte Death and Heart Dysfunction
- (2020) Qingxun Hu et al. CIRCULATION RESEARCH
- Mitochondrial LonP1 protects cardiomyocytes from ischemia/reperfusion injury in vivo
- (2019) Sundararajan Venkatesh et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Propofol Ameliorates H9c2 Cells Apoptosis Induced by Oxygen Glucose Deprivation and Reperfusion Injury via Inhibiting High Levels of Mitochondrial Fusion and Fission
- (2019) Lidong Zhao et al. Frontiers in Pharmacology
- Post-Translational Modifications of Mitochondrial Fission and Fusion Proteins in Cardiac Physiology and Pathophysiology
- (2019) Stephane M Adaniya et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Drp1/Fis1 interaction mediates mitochondrial dysfunction in septic cardiomyopathy
- (2019) Bereketeab Haileselassie et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Cardioprotective Effect of the Mitochondrial Unfolded Protein Response During Chronic Pressure Overload
- (2019) Ioannis Smyrnias et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Zinc-Induced SUMOylation of Dynamin-Related Protein 1 Protects the Heart against Ischemia-Reperfusion Injury
- (2019) Xiyun Bian et al. Oxidative Medicine and Cellular Longevity
- Cardioprotection by the mitochondrial unfolded protein response requires ATF5
- (2019) Yves T. Wang et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Targeting Mitochondrial Fission Using Mdivi-1 in A Clinically Relevant Large Animal Model of Acute Myocardial Infarction: A Pilot Study
- (2019) Sang-Bing Ong et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Mitochondrial fusion mediated by fusion promotion and fission inhibition directs adult mouse heart function toward a different direction
- (2019) Yuan Qin et al. FASEB JOURNAL
- Identification of novel dynamin‐related protein 1 (Drp1) GTPase inhibitors: Therapeutic potential of Drpitor1 and Drpitor1a in cancer and cardiac ischemia‐reperfusion injury
- (2019) Danchen Wu et al. FASEB JOURNAL
- Brain-derived neurotrophic factor mimetic, 7,8-dihydroxyflavone, protects against myocardial ischemia by rebalancing optic atrophy 1 processing
- (2019) Zhen Wang et al. FREE RADICAL BIOLOGY AND MEDICINE
- BI1 is associated with microvascular protection in cardiac ischemia reperfusion injury via repressing Syk–Nox2–Drp1-mitochondrial fission pathways
- (2018) Hao Zhou et al. ANGIOGENESIS
- The Role of Autophagy in the Heart
- (2018) Sebastiano Sciarretta et al. Annual Review of Physiology
- Vagus nerve stimulation exerts cardioprotection against myocardial ischemia/reperfusion injury predominantly through its efferent vagal fibers
- (2018) Watthana Nuntaphum et al. BASIC RESEARCH IN CARDIOLOGY
- NR4A1 aggravates the cardiac microvascular ischemia reperfusion injury through suppressing FUNDC1-mediated mitophagy and promoting Mff-required mitochondrial fission by CK2α
- (2018) Hao Zhou et al. BASIC RESEARCH IN CARDIOLOGY
- Epigenetic Dysregulation of the Dynamin-Related Protein 1 Binding Partners MiD49 and MiD51 Increases Mitotic Mitochondrial Fission and Promotes Pulmonary Arterial Hypertension
- (2018) Kuang-Hueih Chen et al. CIRCULATION
- The desumoylating enzyme sentrin-specific protease 3 contributes to myocardial ischemia reperfusion injury
- (2018) Lingchen Gao et al. Journal of Genetics and Genomics
- TLR4 Activation Promotes the Progression of Experimental Autoimmune Myocarditis to Dilated Cardiomyopathy by Inducing Mitochondrial Dynamic Imbalance
- (2018) Bangwei Wu et al. Oxidative Medicine and Cellular Longevity
- Succinate induces aberrant mitochondrial fission in cardiomyocytes through GPR91 signaling
- (2018) Yi-Tong Lu et al. Cell Death & Disease
- DUSP1 alleviates cardiac ischemia/reperfusion injury by suppressing the Mff-required mitochondrial fission and Bnip3-related mitophagy via the JNK pathways
- (2018) Qinhua Jin et al. Redox Biology
- Empagliflozin rescues diabetic myocardial microvascular injury via AMPK-mediated inhibition of mitochondrial fission
- (2018) Hao Zhou et al. Redox Biology
- The cristae modulator Optic atrophy 1 requires mitochondrial ATP synthase oligomers to safeguard mitochondrial function
- (2018) Rubén Quintana-Cabrera et al. Nature Communications
- The coronary circulation in acute myocardial ischaemia/reperfusion injury: a target for cardioprotection
- (2018) Derek J Hausenloy et al. CARDIOVASCULAR RESEARCH
- Sirt3 attenuates post-infarction cardiac injury via inhibiting mitochondrial fission and normalization of AMPK-Drp1 pathways
- (2018) Jixuan Liu et al. CELLULAR SIGNALLING
- An alternative mitophagy pathway mediated by Rab9 protects the heart against ischemia
- (2018) Toshiro Saito et al. JOURNAL OF CLINICAL INVESTIGATION
- Melatonin attenuates myocardial ischemia reperfusion injury via improving mitochondrial fusion/mitophagy and activating the AMPK-OPA1 signaling pathways
- (2018) Ying Zhang et al. JOURNAL OF PINEAL RESEARCH
- What role does the stress response have in congestive heart failure?
- (2017) Ahmed Badreddin et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Cardioprotection of dapagliflozin and vildagliptin in rats with cardiac ischemia-reperfusion injury
- (2017) Pongpan Tanajak et al. JOURNAL OF ENDOCRINOLOGY
- Melatonin protects cardiac microvasculature against ischemia/reperfusion injury via suppression of mitochondrial fission-VDAC1-HK2-mPTP-mitophagy axis
- (2017) Hao Zhou et al. JOURNAL OF PINEAL RESEARCH
- Mitochondrial fusion dynamics is robust in the heart and depends on calcium oscillations and contractile activity
- (2017) Verónica Eisner et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mdivi-1 Protects Human W8B2+ Cardiac Stem Cells from Oxidative Stress and Simulated Ischemia-Reperfusion Injury
- (2017) Ayeshah A. Rosdah et al. STEM CELLS AND DEVELOPMENT
- Ginsenoside Rg5 increases cardiomyocyte resistance to ischemic injury through regulation of mitochondrial hexokinase-II and dynamin-related protein 1
- (2017) Yi-Lin Yang et al. Cell Death & Disease
- Protective role of STVNa in myocardial ischemia reperfusion injury by inhibiting mitochondrial fission
- (2017) Xiaoou Sun et al. Oncotarget
- Mff‐Dependent Mitochondrial Fission Contributes to the Pathogenesis of Cardiac Microvasculature Ischemia/Reperfusion Injury via Induction of mROS‐Mediated Cardiolipin Oxidation and HK2/VDAC1 Disassociation‐Involved mPTP Opening
- (2017) Hao Zhou et al. Journal of the American Heart Association
- High glucose concentration abrogates sevoflurane post-conditioning cardioprotection by advancing mitochondrial fission but dynamin-related protein 1 inhibitor restores these effects
- (2016) J. Yu et al. Acta Physiologica
- A novel fission-independent role of dynamin-related protein 1 in cardiac mitochondrial respiration
- (2016) Huiliang Zhang et al. CARDIOVASCULAR RESEARCH
- The Transcription Factor ATF5 Mediates a Mammalian Mitochondrial UPR
- (2016) Christopher J. Fiorese et al. CURRENT BIOLOGY
- Vagal nerve stimulation improves mitochondrial dynamicsviaan M3receptor/CaMKKβ/AMPK pathway in isoproterenol-induced myocardial ischaemia
- (2016) Run-Qing Xue et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- DJ-1 protects the heart against ischemia–reperfusion injury by regulating mitochondrial fission
- (2016) Yuuki Shimizu et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Mitochondrial quality control in the diabetic heart
- (2016) Qiangrong Liang et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Correcting mitochondrial fusion by manipulating mitofusin conformations
- (2016) Antonietta Franco et al. NATURE
- Remote Ischemic Conditioning Influences Mitochondrial Dynamics
- (2016) Laura Cellier et al. SHOCK
- Hearts deficient in both Mfn1 and Mfn2 are protected against acute myocardial infarction
- (2016) A R Hall et al. Cell Death & Disease
- Nanoparticle‐Mediated Delivery of Mitochondrial Division Inhibitor 1 to the Myocardium Protects the Heart From Ischemia‐Reperfusion Injury Through Inhibition of Mitochondria Outer Membrane Permeabilization: A New Therapeutic Modality for Acute Myocardial Infarction
- (2016) Ayako Ishikita et al. Journal of the American Heart Association
- Mitochondrial Protein PGAM5 Regulates Mitophagic Protection against Cell Necroptosis
- (2016) Wei Lu et al. PLoS One
- Increase in Cardiac Ischemia-Reperfusion Injuries in Opa1+/- Mouse Model
- (2016) Sophie Le Page et al. PLoS One
- Bicarbonate Increases Ischemia-Reperfusion Damage by Inhibiting Mitophagy
- (2016) Bruno B. Queliconi et al. PLoS One
- Remote ischaemic conditioning: cardiac protection from afar
- (2015) V. Sivaraman et al. ANAESTHESIA
- The Opa1-Dependent Mitochondrial Cristae Remodeling Pathway Controls Atrophic, Apoptotic, and Ischemic Tissue Damage
- (2015) Tatiana Varanita et al. Cell Metabolism
- Mitochondrial Fission and Fusion Factors Reciprocally Orchestrate Mitophagic Culling in Mouse Hearts and Cultured Fibroblasts
- (2015) Moshi Song et al. Cell Metabolism
- OPA1 in Cardiovascular Health and Disease
- (2015) Niall Burke et al. CURRENT DRUG TARGETS
- Mitochondrial fusion and fission proteins as novel therapeutic targets for treating cardiovascular disease
- (2015) Sang-Bing Ong et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Titration of mitochondrial fusion rescuesMff-deficient cardiomyopathy
- (2015) Hsiuchen Chen et al. JOURNAL OF CELL BIOLOGY
- Dissociation of mitochondrial from sarcoplasmic reticular stress in Drosophila cardiomyopathy induced by molecularly distinct mitochondrial fusion defects
- (2015) Poonam Bhandari et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Functional implications of mitofusin 2-mediated mitochondrial-SR tethering
- (2015) Gerald W. Dorn et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Imbalanced OPA1 processing and mitochondrial fragmentation cause heart failure in mice
- (2015) T. Wai et al. SCIENCE
- Parkin-mediated mitophagy directs perinatal cardiac metabolic maturation in mice
- (2015) G. Gong et al. SCIENCE
- Akt protects the heart against ischaemia-reperfusion injury by modulating mitochondrial morphology
- (2015) Sang-Bing Ong et al. THROMBOSIS AND HAEMOSTASIS
- Actin filaments target the oligomeric maturation of the dynamin GTPase Drp1 to mitochondrial fission sites
- (2015) Wei-ke Ji et al. eLife
- PINK1 Is Dispensable for Mitochondrial Recruitment of Parkin and Activation of Mitophagy in Cardiac Myocytes
- (2015) Dieter A. Kubli et al. PLoS One
- Cdk1, PKCδ and calcineurin-mediated Drp1 pathway contributes to mitochondrial fission-induced cardiomyocyte death
- (2014) Ivan Zaja et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Parkin‐independent mitophagy requires Drp1 and maintains the integrity of mammalian heart and brain
- (2014) Yusuke Kageyama et al. EMBO JOURNAL
- Aerobic Interval Training Attenuates Mitochondrial Dysfunction in Rats Post-Myocardial Infarction: Roles of Mitochondrial Network Dynamics
- (2014) Hong-Ke Jiang et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Drp1 Loss-of-function Reduces Cardiomyocyte Oxygen Dependence Protecting the Heart From Ischemia-reperfusion Injury
- (2014) Ramiro Zepeda et al. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
- Dynamics of Mitochondrial DNA Nucleoids Regulated by Mitochondrial Fission Is Essential for Maintenance of Homogeneously Active Mitochondria during Neonatal Heart Development
- (2014) Takaya Ishihara et al. MOLECULAR AND CELLULAR BIOLOGY
- DJ-1 protects against cell death following acute cardiac ischemia–reperfusion injury
- (2014) R K Dongworth et al. Cell Death & Disease
- Mitophagy Is Required for Acute Cardioprotection by Simvastatin
- (2013) Allen M. Andres et al. ANTIOXIDANTS & REDOX SIGNALING
- Nitrite activates protein kinase A in normoxia to mediate mitochondrial fusion and tolerance to ischaemia/reperfusion
- (2013) Christelle Kamga Pride et al. CARDIOVASCULAR RESEARCH
- Mitochondrial Cristae Shape Determines Respiratory Chain Supercomplexes Assembly and Respiratory Efficiency
- (2013) Sara Cogliati et al. CELL
- Mfn2 modulates the UPR and mitochondrial function via repression of PERK
- (2013) Juan Pablo Muñoz et al. EMBO JOURNAL
- SENP3-mediated deSUMOylation of dynamin-related protein 1 promotes cell death following ischaemia
- (2013) Chun Guo et al. EMBO JOURNAL
- Dynamin-related protein 1 (Drp1)-mediated diastolic dysfunction in myocardial ischemia-reperfusion injury: therapeutic benefits of Drp1 inhibition to reduce mitochondrial fission
- (2013) Willard W. Sharp et al. FASEB JOURNAL
- miR-761 regulates the mitochondrial network by targeting mitochondrial fission factor
- (2013) Bo Long et al. FREE RADICAL BIOLOGY AND MEDICINE
- A selective inhibitor of Drp1, mdivi-1, acts against cerebral ischemia/reperfusion injury via an anti-apoptotic pathway in rats
- (2013) Ning Zhang et al. NEUROSCIENCE LETTERS
- Loss of PINK1 Increases the Heart's Vulnerability to Ischemia-Reperfusion Injury
- (2013) Hilary K. Siddall et al. PLoS One
- Dynasore Protects Mitochondria and Improves Cardiac Lusitropy in Langendorff Perfused Mouse Heart
- (2013) Danchen Gao et al. PLoS One
- Attenuation of Doxorubicin-Induced Cardiotoxicity by mdivi-1: A Mitochondrial Division/Mitophagy Inhibitor
- (2013) Mayel Gharanei et al. PLoS One
- Pim-1 preserves mitochondrial morphology by inhibiting dynamin-related protein 1 translocation
- (2013) S. Din et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Kissing and nanotunneling mediate intermitochondrial communication in the heart
- (2013) X. Huang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- An Actin-Dependent Step in Mitochondrial Fission Mediated by the ER-Associated Formin INF2
- (2013) F. Korobova et al. SCIENCE
- PINK1-Phosphorylated Mitofusin 2 Is a Parkin Receptor for Culling Damaged Mitochondria
- (2013) Y. Chen et al. SCIENCE
- OPA1 Mutation and Late‐Onset Cardiomyopathy: Mitochondrial Dysfunction and mtDNA Instability
- (2013) Le Chen et al. Journal of the American Heart Association
- Acute Inhibition of Excessive Mitochondrial Fission After Myocardial Infarction Prevents Long‐term Cardiac Dysfunction
- (2013) Marie‐Hélène Disatnik et al. Journal of the American Heart Association
- Mitofusins and the mitochondrial permeability transition: the potential downside of mitochondrial fusion
- (2012) Kyriakos N. Papanicolaou et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Mitochondrial Dynamics in Cardiovascular Health and Disease
- (2012) Sang-Bing Ong et al. ANTIOXIDANTS & REDOX SIGNALING
- Down-regulation of OPA1 alters mouse mitochondrial morphology, PTP function, and cardiac adaptation to pressure overload
- (2012) Jerome Piquereau et al. CARDIOVASCULAR RESEARCH
- Mitofusin 2-Containing Mitochondrial-Reticular Microdomains Direct Rapid Cardiomyocyte Bioenergetic Responses Via Interorganelle Ca 2+ Crosstalk
- (2012) Yun Chen et al. CIRCULATION RESEARCH
- Mitofusins 1 and 2 Are Essential for Postnatal Metabolic Remodeling in Heart
- (2012) Kyriakos N. Papanicolaou et al. CIRCULATION RESEARCH
- Mouse lines with photo-activatable mitochondria to study mitochondrial dynamics
- (2012) Anh H. Pham et al. GENESIS
- Central Role of Mitofusin 2 in Autophagosome-Lysosome Fusion in Cardiomyocytes
- (2012) Ting Zhao et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Parkin Protein Deficiency Exacerbates Cardiac Injury and Reduces Survival following Myocardial Infarction
- (2012) Dieter A. Kubli et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Loss of Mitofusin 2 Promotes Endoplasmic Reticulum Stress
- (2012) Gladys A. Ngoh et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mitochondrial autophagy by Bnip3 involves Drp1-mediated mitochondrial fission and recruitment of Parkin in cardiac myocytes
- (2011) Youngil Lee et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Cardiomyocyte deletion of mitofusin-1 leads to mitochondrial fragmentation and improves tolerance to ROS-induced mitochondrial dysfunction and cell death
- (2011) Kyriakos N. Papanicolaou et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Mitochondrial Fusion is Essential for Organelle Function and Cardiac Homeostasis
- (2011) Yun Chen et al. CIRCULATION RESEARCH
- MiD49 and MiD51, new components of the mitochondrial fission machinery
- (2011) Catherine S Palmer et al. EMBO REPORTS
- Mitofusin-2 Maintains Mitochondrial Structure and Contributes to Stress-Induced Permeability Transition in Cardiac Myocytes
- (2011) K. N. Papanicolaou et al. MOLECULAR AND CELLULAR BIOLOGY
- Preconditioning Involves Selective Mitophagy Mediated by Parkin and p62/SQSTM1
- (2011) Chengqun Huang et al. PLoS One
- ER Tubules Mark Sites of Mitochondrial Division
- (2011) J. R. Friedman et al. SCIENCE
- Regulation of mitochondrial fission by intracellular Ca2+ in rat ventricular myocytes
- (2010) Jennifer Hom et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Mitochondrial morphology and cardiovascular disease
- (2010) S.-B. Ong et al. CARDIOVASCULAR RESEARCH
- Inhibiting Mitochondrial Fission Protects the Heart Against Ischemia/Reperfusion Injury
- (2010) Sang-Bing Ong et al. CIRCULATION
- Two Close, Too Close
- (2010) Gerald W. Dorn et al. CIRCULATION RESEARCH
- Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin
- (2010) Atsushi Tanaka et al. JOURNAL OF CELL BIOLOGY
- miR-499 regulates mitochondrial dynamics by targeting calcineurin and dynamin-related protein-1
- (2010) Jian-Xun Wang et al. NATURE MEDICINE
- Mitochondrial OPA1, apoptosis, and heart failure
- (2009) Le Chen et al. CARDIOVASCULAR RESEARCH
- Regulation of mitochondrial dynamics in acute kidney injury in cell culture and rodent models
- (2009) Craig Brooks et al. JOURNAL OF CLINICAL INVESTIGATION
- The Novel Tail-anchored Membrane Protein Mff Controls Mitochondrial and Peroxisomal Fission in Mammalian Cells
- (2008) Shilpa Gandre-Babbe et al. MOLECULAR BIOLOGY OF THE CELL
- Mitofusin 2 tethers endoplasmic reticulum to mitochondria
- (2008) Olga Martins de Brito et al. NATURE
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