Melatonin protects cardiac microvasculature against ischemia/reperfusion injury via suppression of mitochondrial fission-VDAC1-HK2-mPTP-mitophagy axis

Mitochondrial cristae remodelling is associated with disrupted OPA1 oligomerisation in the Huntington's disease R6/2 fragment model

(2017) Tanja Hering et al.   EXPERIMENTAL NEUROLOGY

Melatonin pretreatment improves gastric mucosal blood flow and maintains intestinal barrier function during hemorrhagic shock in dogs

(2017) Christian Vollmer et al.   MICROCIRCULATION

Mff‐Dependent Mitochondrial Fission Contributes to the Pathogenesis of Cardiac Microvasculature Ischemia/Reperfusion Injury via Induction of mROS‐Mediated Cardiolipin Oxidation and HK2/VDAC1 Disassociation‐Involved mPTP Opening

(2017) Hao Zhou et al.   Journal of the American Heart Association

Lack of Adipocyte AMPK Exacerbates Insulin Resistance and Hepatic Steatosis through Brown and Beige Adipose Tissue Function

(2016) Emilio P. Mottillo et al.   Cell Metabolism

Metformin Suppresses Diabetes-Accelerated Atherosclerosis via the Inhibition of Drp1-Mediated Mitochondrial Fission

(2016) Qilong Wang et al.   DIABETES

Liraglutide protects cardiac microvascular endothelial cells against hypoxia/reoxygenation injury through the suppression of the SR-Ca2+–XO–ROS axis via activation of the GLP-1R/PI3K/Akt/survivin pathways

(2016) Ying Zhang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Melatonin reverses flow shear stress-induced injury in bone marrow mesenchymal stem cells via activation of AMP-activated protein kinase signaling

(2016) Yang Yang et al.   JOURNAL OF PINEAL RESEARCH

Melatonin attenuates traumatic brain injury-induced inflammation: a possible role for mitophagy

(2016) Chao Lin et al.   JOURNAL OF PINEAL RESEARCH

Aldehyde Dehydrogenase 2 Has Cardioprotective Effects on Myocardial Ischaemia/Reperfusion Injury via Suppressing Mitophagy

(2016) Wenqing Ji et al.   Frontiers in Pharmacology

Melatonin Preserves Blood-Brain Barrier Integrity and Permeability via Matrix Metalloproteinase-9 Inhibition

(2016) Himakarnika Alluri et al.   PLoS One

Melatonin facilitates adipose-derived mesenchymal stem cells to repair the murine infarcted heartviathe SIRT1 signaling pathway

(2015) Dong Han et al.   JOURNAL OF PINEAL RESEARCH

Parkinson's disease proteins: Novel mitochondrial targets for cardioprotection

(2015) Uma A. Mukherjee et al.   PHARMACOLOGY & THERAPEUTICS

Myristoylation confers noncanonical AMPK functions in autophagy selectivity and mitochondrial surveillance

(2015) Jiyong Liang et al.   Nature Communications

Effects of Exendin-4 on bone marrow mesenchymal stem cell proliferation, migration and apoptosis in vitro

(2015) Hao Zhou et al.   Scientific Reports

Exendin-4 protects adipose-derived mesenchymal stem cells from apoptosis induced by hydrogen peroxide through the PI3K/Akt–Sfrp2 pathways

(2014) Hao Zhou et al.   FREE RADICAL BIOLOGY AND MEDICINE

Melatonin prevents mitochondrial dysfunction and insulin resistance in rat skeletal muscle

(2014) Bruno G. Teodoro et al.   JOURNAL OF PINEAL RESEARCH

Melatonin inhibits thermal injury–induced hyperpermeability in microvascular endothelial cells

(2014) Katie Wiggins-Dohlvik et al.   Journal of Trauma and Acute Care Surgery

Phosphomimetic Modulation of eNOS Improves Myocardial Reperfusion and Mimics Cardiac Postconditioning in Mice

(2014) Terrence Pong et al.   PLoS One

Does microvascular disease predict macrovascular events in type 2 diabetes?

(2011) R.S. Rosenson et al.   ATHEROSCLEROSIS

Inhibiting Mitochondrial Fission Protects the Heart Against Ischemia/Reperfusion Injury

(2010) Sang-Bing Ong et al.   CIRCULATION

Microvascular Obstruction Remains a Portent of Adverse Remodeling in Optimally Treated Patients With Left Ventricular Systolic Dysfunction After Acute Myocardial Infarction

(2010) Robin A.P. Weir et al.   Circulation-Cardiovascular Imaging

5-Year Prognostic Value of No-Reflow Phenomenon After Percutaneous Coronary Intervention in Patients With Acute Myocardial Infarction

(2010) Gjin Ndrepepa et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Anesthetic-induced Preconditioning Delays Opening of Mitochondrial Permeability Transition Pore via Protein Kinase C-ϵ–mediated Pathway

(2009) Danijel Pravdic et al.   ANESTHESIOLOGY

Mitochondrial hexokinase and cardioprotection of the intact heart

(2009) C. J. Zuurbier et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

What is the mitochondrial permeability transition pore?

(2009) Andrew P. Halestrap   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

No-reflow: the next challenge in treatment of ST-elevation acute myocardial infarction

(2008) A. Abbate et al.   EUROPEAN HEART JOURNAL

Regulation of hexokinase binding to VDAC

(2008) John G. Pastorino et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES