Mitofusins and the mitochondrial permeability transition: the potential downside of mitochondrial fusion

Down-regulation of OPA1 alters mouse mitochondrial morphology, PTP function, and cardiac adaptation to pressure overload

(2012) Jerome Piquereau et al.   CARDIOVASCULAR RESEARCH

Loss of Mitofusin 2 Promotes Endoplasmic Reticulum Stress

(2012) Gladys A. Ngoh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mutations in the ER-shaping protein reticulon 2 cause the axon-degenerative disorder hereditary spastic paraplegia type 12

(2012) Gladys Montenegro et al.   JOURNAL OF CLINICAL INVESTIGATION

Bax regulates primary necrosis through mitochondrial dynamics

(2012) R. S. Whelan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alignment of sarcoplasmic reticulum-mitochondrial junctions with mitochondrial contact points

(2011) Cecília García-Pérez et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Cardiomyocyte deletion of mitofusin-1 leads to mitochondrial fragmentation and improves tolerance to ROS-induced mitochondrial dysfunction and cell death

(2011) Kyriakos N. Papanicolaou et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Weaving the Web of ER Tubules

(2011) Junjie Hu et al.   CELL

Mitochondria in Apoptosis: Bcl-2 Family Members and Mitochondrial Dynamics

(2011) Jean-Claude Martinou et al.   DEVELOPMENTAL CELL

The mitochondrial contact site complex, a determinant of mitochondrial architecture

(2011) Max Harner et al.   EMBO JOURNAL

Bioenergetic defect associated with mKATP channel opening in a mouse model carrying a mitofusin 2 mutation

(2011) Virginie Guillet et al.   FASEB JOURNAL

Making heads or tails of phospholipids in mitochondria

(2011) Christof Osman et al.   JOURNAL OF CELL BIOLOGY

Mitofusins are required for angiogenic function and modulate different signaling pathways in cultured endothelial cells

(2011) Jesse J. Lugus et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Mitofusin-2 Maintains Mitochondrial Structure and Contributes to Stress-Induced Permeability Transition in Cardiac Myocytes

(2011) K. N. Papanicolaou et al.   MOLECULAR AND CELLULAR BIOLOGY

Membrane fusion catalyzed by a Rab, SNAREs, and SNARE chaperones is accompanied by enhanced permeability to small molecules and by lysis

(2011) Paola C. Zucchi et al.   MOLECULAR BIOLOGY OF THE CELL

The Soluble Form of Bax Regulates Mitochondrial Fusion via MFN2 Homotypic Complexes

(2011) Suzanne Hoppins et al.   MOLECULAR CELL

TLR signalling augments macrophage bactericidal activity through mitochondrial ROS

(2011) A. Phillip West et al.   NATURE

Membrane fusion by the GTPase atlastin requires a conserved C-terminal cytoplasmic tail and dimerization through the middle domain

(2011) T. J. Moss et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structures of the atlastin GTPase provide insight into homotypic fusion of endoplasmic reticulum membranes

(2011) X. Bian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural basis for the nucleotide-dependent dimerization of the large G protein atlastin-1/SPG3A

(2011) L. J. Byrnes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A lipid-anchored SNARE supports membrane fusion

(2011) H. Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Membrane Fusion: Five Lipids, Four SNAREs, Three Chaperones, Two Nucleotides, and a Rab, All Dancing in a Ring on Yeast Vacuoles

(2010) William Wickner   Annual Review of Cell and Developmental Biology

The Cardiac Mitochondrion: Nexus of Stress

(2010) Christopher P. Baines   Annual Review of Physiology

Mitochondrial Fusion Is Required for mtDNA Stability in Skeletal Muscle and Tolerance of mtDNA Mutations

(2010) Hsiuchen Chen et al.   CELL

Membrane Remodeling Induced by the Dynamin-Related Protein Drp1 Stimulates Bax Oligomerization

(2010) Sylvie Montessuit et al.   CELL

Bcl-2 family interaction with the mitochondrial morphogenesis machinery

(2010) M M Cleland et al.   CELL DEATH AND DIFFERENTIATION

Bioenergetic function in cardiovascular cells: The importance of the reserve capacity and its biological regulation

(2010) Brian E. Sansbury et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Inhibiting Mitochondrial Fission Protects the Heart Against Ischemia/Reperfusion Injury

(2010) Sang-Bing Ong et al.   CIRCULATION

Architecture of a nascent viral fusion pore

(2010) Kelly K Lee   EMBO JOURNAL

Regulation of the Inner Membrane Mitochondrial Permeability Transition by the Outer Membrane Translocator Protein (Peripheral Benzodiazepine Receptor)

(2010) Justina Šileikytė et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Membrane Fusion: the Emergence of a New Paradigm

(2010) M. Schick   JOURNAL OF STATISTICAL PHYSICS

Conformational changes in Dnm1 support a contractile mechanism for mitochondrial fission

(2010) Jason A Mears et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Importance of the bioenergetic reserve capacity in response to cardiomyocyte stress induced by 4-hydroxynonenal

(2009) Bradford G. Hill et al.   BIOCHEMICAL JOURNAL

A Class of Dynamin-like GTPases Involved in the Generation of the Tubular ER Network

(2009) Junjie Hu et al.   CELL

Mitochondrial Cardiolipin Involved in Outer-Membrane Protein Biogenesis: Implications for Barth Syndrome

(2009) Natalia Gebert et al.   CURRENT BIOLOGY

SLP-2 is required for stress-induced mitochondrial hyperfusion

(2009) Daniel Tondera et al.   EMBO JOURNAL

Assembly of the Mitochondrial Apoptosis-induced Channel, MAC

(2009) Sonia Martinez-Caballero et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Morphological dynamics of mitochondria — A special emphasis on cardiac muscle cells

(2009) Jennifer Hom et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Homotypic fusion of ER membranes requires the dynamin-like GTPase Atlastin

(2009) Genny Orso et al.   NATURE

Metalloprotease-mediated OPA1 processing is modulated by the mitochondrial membrane potential

(2008) Olwenn Guillery et al.   BIOLOGY OF THE CELL

Structural implications of mitochondrial dynamics

(2008) Jürgen Bereiter-Hahn et al.   Biotechnology Journal

Contributions to Bax insertion and oligomerization of lipids of the mitochondrial outer membrane

(2008) S Lucken-Ardjomande et al.   CELL DEATH AND DIFFERENTIATION

Structures and Mechanisms of Viral Membrane Fusion Proteins: Multiple Variations on a Common Theme

(2008) Judith M. White et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

(2008) Gilad Twig et al.   EMBO JOURNAL

Reconstituted membrane fusion requires regulatory lipids, SNAREs and synergistic SNARE chaperones

(2008) Joji Mima et al.   EMBO JOURNAL

Membrane lysis during biological membrane fusion: collateral damage by misregulated fusion machines

(2008) Alex Engel et al.   JOURNAL OF CELL BIOLOGY

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

(2008) Derek Narendra et al.   JOURNAL OF CELL BIOLOGY

Mitofusin 2 tethers endoplasmic reticulum to mitochondria

(2008) Olga Martins de Brito et al.   NATURE

Mechanisms of membrane fusion: disparate players and common principles

(2008) Sascha Martens et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mechanics of membrane fusion

(2008) Leonid V Chernomordik et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY