Vagus nerve stimulation exerts cardioprotection against myocardial ischemia/reperfusion injury predominantly through its efferent vagal fibers

Low-Level Tragus Stimulation for the Treatment of Ischemia and Reperfusion Injury in Patients With ST-Segment Elevation Myocardial Infarction

(2017) Lilei Yu et al.   JACC-Cardiovascular Interventions

Vagal Cardioprotection in Reperfused Acute Myocardial Infarction ∗

(2017) Gerd Heusch   JACC-Cardiovascular Interventions

Nicotinic Acetylcholine Receptor—Mediated Protection of the Rat Heart Exposed to Ischemia Reperfusion

(2017) Spyros A Mavropoulos et al.   MOLECULAR MEDICINE

Kilohertz frequency nerve block enhances anti-inflammatory effects of vagus nerve stimulation

(2017) Yogi A. Patel et al.   Scientific Reports

Glucagon-like peptide-1 (GLP-1) mediates cardioprotection by remote ischaemic conditioning

(2016) Marina V. Basalay et al.   CARDIOVASCULAR RESEARCH

Autonomic regulation therapy suppresses quantitative T-wave alternans and improves baroreflex sensitivity in patients with heart failure enrolled in the ANTHEM-HF study

(2016) Imad Libbus et al.   HEART RHYTHM

Vagal nerve stimulation improves mitochondrial dynamicsviaan M3receptor/CaMKKβ/AMPK pathway in isoproterenol-induced myocardial ischaemia

(2016) Run-Qing Xue et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Cardioprotection by remote ischemic conditioning and its signal transduction

(2016) Petra Kleinbongard et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Vagus Nerve Stimulation Improves Cardiac Function by Preventing Mitochondrial Dysfunction in Obese-Insulin Resistant Rats

(2016) Bencharunan Samniang et al.   Scientific Reports

Vagus Nerve Stimulation Exerts the Neuroprotective Effects in Obese-Insulin Resistant Rats, Leading to the Improvement of Cognitive Function

(2016) Titikorn Chunchai et al.   Scientific Reports

Cardioprotection by combination of three compounds from ShengMai preparations in mice with myocardial ischemia/reperfusion injury through AMPK activation-mediated mitochondrial fission

(2016) Fang Li et al.   Scientific Reports

Vagal nerve stimulation activates vagal afferent fibers that reduce cardiac efferent parasympathetic effects

(2015) Kentaro Yamakawa et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Vagal nerve stimulation started just prior to reperfusion limits infarct size and no-reflow

(2015) André Uitterdijk et al.   BASIC RESEARCH IN CARDIOLOGY

Molecular Basis of Cardioprotection: Signal Transduction in Ischemic Pre-, Post-, and Remote Conditioning

(2015) G. Heusch   CIRCULATION RESEARCH

Vagus Nerve and Vagus Nerve Stimulation, a Comprehensive Review: Part I

(2015) Hsiangkuo Yuan et al.   HEADACHE

Combined Vagal Stimulation and Limb Remote Ischemic Perconditioning Enhances Cardioprotection via an Anti-inflammatory Pathway

(2015) Qiang Wang et al.   INFLAMMATION

Chronic vagal stimulation for the treatment of low ejection fraction heart failure: results of the NEural Cardiac TherApy foR Heart Failure (NECTAR-HF) randomized controlled trial

(2014) Faiez Zannad et al.   EUROPEAN HEART JOURNAL

Vagus nerve stimulation initiated late during ischemia, but not reperfusion, exerts cardioprotection via amelioration of cardiac mitochondrial dysfunction

(2014) Krekwit Shinlapawittayatorn et al.   HEART RHYTHM

Autonomic Regulation Therapy via Left or Right Cervical Vagus Nerve Stimulation in Patients With Chronic Heart Failure: Results of the ANTHEM-HF Trial

(2014) Rajendra K. Premchand et al.   JOURNAL OF CARDIAC FAILURE

Exercise training reduces resting heart rate via downregulation of the funny channel HCN4

(2014) Alicia D’Souza et al.   Nature Communications

Impaired mitochondrial biogenesis due to dysfunctional adiponectin-AMPK-PGC-1α signaling contributing to increased vulnerability in diabetic heart

(2013) Wenjun Yan et al.   BASIC RESEARCH IN CARDIOLOGY

Vagal stimulation triggers peripheral vascular protection through the cholinergic anti-inflammatory pathway in a rat model of myocardial ischemia/reperfusion

(2013) Ming Zhao et al.   BASIC RESEARCH IN CARDIOLOGY

Acetylcholine Mediates AMPK-Dependent Autophagic Cytoprotection in H9c2 Cells During Hypoxia/Reoxygenation Injury

(2013) Mei Zhao et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

C-Peptide Activates AMPK  and Prevents ROS-Mediated Mitochondrial Fission and Endothelial Apoptosis in Diabetes

(2013) M. P. Bhatt et al.   DIABETES

Mechanisms responsible for beneficial and adverse effects of rosiglitazone in a rat model of acute cardiac ischaemia-reperfusion

(2013) Siripong Palee et al.   EXPERIMENTAL PHYSIOLOGY

Low-amplitude, left vagus nerve stimulation significantly attenuates ventricular dysfunction and infarct size through prevention of mitochondrial dysfunction during acute ischemia-reperfusion injury

(2013) Krekwit Shinlapawittayatorn et al.   HEART RHYTHM

Autonomic Regulation Therapy for the Improvement of Left Ventricular Function and Heart Failure Symptoms: The ANTHEM-HF Study

(2013) Lorenzo Dicarlo et al.   JOURNAL OF CARDIAC FAILURE

Myths and realities of the cardiac vagus

(2013) J. H. Coote   JOURNAL OF PHYSIOLOGY-LONDON

The Lambeth Conventions (II): Guidelines for the study of animal and human ventricular and supraventricular arrhythmias

(2013) Michael J. Curtis et al.   PHARMACOLOGY & THERAPEUTICS

Rationale and study design of the INcrease Of Vagal TonE in Heart Failure study: INOVATE-HF

(2012) Paul J. Hauptman et al.   AMERICAN HEART JOURNAL

Calcium-induced Cardiac Mitochondrial Dysfunction Is Predominantly Mediated by Cyclosporine A-dependent Mitochondrial Permeability Transition Pore

(2012) Chontida Yarana et al.   ARCHIVES OF MEDICAL RESEARCH

Cardioprotection evoked by remote ischaemic preconditioning is critically dependent on the activity of vagal pre-ganglionic neurones

(2012) Svetlana Mastitskaya et al.   CARDIOVASCULAR RESEARCH

Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling

(2012) Paul D. Ray et al.   CELLULAR SIGNALLING

Role of the parasympathetic nervous system in cardioprotection by remote hindlimb ischaemic preconditioning

(2012) Martín Donato et al.   EXPERIMENTAL PHYSIOLOGY

Mechanisms underlying the autonomic modulation of ventricular fibrillation initiation—tentative prophylactic properties of vagus nerve stimulation on malignant arrhythmias in heart failure

(2012) Kieran E. Brack et al.   HEART FAILURE REVIEWS

Cardioprotective effect of dipeptidyl peptidase-4 inhibitor during ischemia–reperfusion injury

(2012) Kroekkiat Chinda et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Protection against Ischemia-Induced Oxidative Stress Conferred by Vagal Stimulation in the Rat Heart: Involvement of the AMPK-PKC Pathway

(2012) Shan-Shan Kong et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cardioprotection by acetylcholine: A novel mechanism via mitochondrial biogenesis and function involving the PGC-1α pathway

(2012) Lei Sun et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Fusion and Fission: Interlinked Processes Critical for Mitochondrial Health

(2011) David C. Chan   Annual Review of Genetics

Vagal Stimulation, Through its Nicotinic Action, Limits Infarct Size and the Inflammatory Response to Myocardial Ischemia and Reperfusion

(2011) Laura Calvillo et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Mitochondrial connexin 43 impacts on respiratory complex I activity and mitochondrial oxygen consumption

(2011) Kerstin Boengler et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Granulocyte-colony stimulating factor attenuates mitochondrial dysfunction induced by oxidative stress in cardiac mitochondria

(2011) Savitree Thummasorn et al.   MITOCHONDRION

Dynamic regulation of mitochondrial fission through modification of the dynamin-related protein Drp1

(2010) Chuang-Rung Chang et al.   Annals of the New York Academy of Sciences

Physiological functions of mitochondrial fusion

(2010) Hsiuchen Chen et al.   Annals of the New York Academy of Sciences

Cell Death in the Pathogenesis of Heart Disease: Mechanisms and Significance

(2010) Russell S. Whelan et al.   Annual Review of Physiology

Cardiac mitochondria and arrhythmias

(2010) D. A. Brown et al.   CARDIOVASCULAR RESEARCH

Alterations of muscarinic acetylcholine receptors-2, 4 and α7-nicotinic acetylcholine receptor expression after ischaemia / reperfusion in the rat isolated heart

(2010) Dong-Ling Li et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Chronic vagus nerve stimulation: a new and promising therapeutic approach for chronic heart failure

(2010) Gaetano M. De Ferrari et al.   EUROPEAN HEART JOURNAL

Myc controls transcriptional regulation of cardiac metabolism and mitochondrial biogenesis in response to pathological stress in mice

(2010) Preeti Ahuja et al.   JOURNAL OF CLINICAL INVESTIGATION

Mitochondrial fusion proteins: Dual regulators of morphology and metabolism

(2010) Antonio Zorzano et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Loss of Anti-Arrhythmic Effect of Vagal Nerve Stimulation on Ischemia-Induced Ventricular Tachyarrhythmia in Aged Rats

(2010) Wei Wu et al.   TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE

Vagal nerve stimulation prevents reperfusion injury through inhibition of opening of mitochondrial permeability transition pore independent of the bradycardiac effect

(2009) Rajesh G. Katare et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

Effects of 4'-chlorodiazepam on cellular excitation-contraction coupling and ischaemia-reperfusion injury in rabbit heart

(2008) D. A. Brown et al.   CARDIOVASCULAR RESEARCH

Long term vagal stimulation in patients with advanced heart failure First experience in man

(2008) Peter J. Schwartz et al.   EUROPEAN JOURNAL OF HEART FAILURE