Mitochondrial Dynamics in Cardiovascular Health and Disease

The shape of things to come: mitochondrial fusion and fission in the adult heart

(2012) A. R. Hall et al.   CARDIOVASCULAR RESEARCH

Down-regulation of OPA1 alters mouse mitochondrial morphology, PTP function, and cardiac adaptation to pressure overload

(2012) Jerome Piquereau et al.   CARDIOVASCULAR RESEARCH

Cardiomyocyte deletion of mitofusin-1 leads to mitochondrial fragmentation and improves tolerance to ROS-induced mitochondrial dysfunction and cell death

(2011) Kyriakos N. Papanicolaou et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Regulation of mitochondrial morphology and function by O-GlcNAcylation in neonatal cardiac myocytes

(2011) Ayako Makino et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Altered fusion dynamics underlie unique morphological changes in mitochondria during hypoxia–reoxygenation stress

(2011) X Liu et al.   CELL DEATH AND DIFFERENTIATION

Mitochondrial Fusion is Essential for Organelle Function and Cardiac Homeostasis

(2011) Yun Chen et al.   CIRCULATION RESEARCH

The Permeability Transition Pore Controls Cardiac Mitochondrial Maturation and Myocyte Differentiation

(2011) Jennifer R. Hom et al.   DEVELOPMENTAL CELL

Human MIEF1 recruits Drp1 to mitochondrial outer membranes and promotes mitochondrial fusion rather than fission

(2011) Jian Zhao et al.   EMBO JOURNAL

MiD49 and MiD51, new components of the mitochondrial fission machinery

(2011) Catherine S Palmer et al.   EMBO REPORTS

34 Mitochondrial morphology affects cardiomyocyte differentiation of mouse embryonic stem cells through calcineurin and notch signalling pathways

(2011) A. Kasahara et al.   HEART

Mitofusins are required for angiogenic function and modulate different signaling pathways in cultured endothelial cells

(2011) Jesse J. Lugus et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Mitofusin-2 Maintains Mitochondrial Structure and Contributes to Stress-Induced Permeability Transition in Cardiac Myocytes

(2011) K. N. Papanicolaou et al.   MOLECULAR AND CELLULAR BIOLOGY

High Glucose Disrupts Mitochondrial Morphology in Retinal Endothelial Cells

(2010) Kyle Trudeau et al.   AMERICAN JOURNAL OF PATHOLOGY

Mutation of the protein kinase A phosphorylation site influences the anti-proliferative activity of mitofusin 2

(2010) Wei Zhou et al.   ATHEROSCLEROSIS

Regulation of mitochondrial fission by intracellular Ca2+ in rat ventricular myocytes

(2010) Jennifer Hom et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Mitochondrial morphology and cardiovascular disease

(2010) S.-B. Ong et al.   CARDIOVASCULAR RESEARCH

Giant Mitochondria in the Myocardium of a Patient With Mitochondrial Cardiomyopathy

(2010) Yumiko Kanzaki et al.   CIRCULATION

Inhibiting Mitochondrial Fission Protects the Heart Against Ischemia/Reperfusion Injury

(2010) Sang-Bing Ong et al.   CIRCULATION

MARF and Opa1 Control Mitochondrial and Cardiac Function in Drosophila

(2010) Gerald W. Dorn et al.   CIRCULATION RESEARCH

Mitochondrial fragmentation and superoxide anion production in coronary endothelial cells from a mouse model of type 1 diabetes

(2010) A. Makino et al.   DIABETOLOGIA

Mff is an essential factor for mitochondrial recruitment of Drp1 during mitochondrial fission in mammalian cells

(2010) Hidenori Otera et al.   JOURNAL OF CELL BIOLOGY

Empowering self-renewal and differentiation: the role of mitochondria in stem cells

(2010) Jalees Rehman   JOURNAL OF MOLECULAR MEDICINE-JMM

miR-499 regulates mitochondrial dynamics by targeting calcineurin and dynamin-related protein-1

(2010) Jian-Xun Wang et al.   NATURE MEDICINE

A Mutation in the Mitochondrial Fission Gene Dnm1l Leads to Cardiomyopathy

(2010) Houman Ashrafian et al.   PLoS Genetics

Mitochondrial OPA1, apoptosis, and heart failure

(2009) Le Chen et al.   CARDIOVASCULAR RESEARCH

The Mechanism of Ca2+-Dependent Regulation of Kinesin-Mediated Mitochondrial Motility

(2009) Xinnan Wang et al.   CELL

Ca2+-dependent regulation of mitochondrial dynamics by the Miro–Milton complex

(2009) Xingguo Liu et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Dynamic organization of mitochondria in human heart and in myocardial disease

(2009) Charles L. Hoppel et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Mitochondria and reperfusion injury of the heart—A holey death but not beyond salvation

(2009) Andrew P. Halestrap   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Regulation of OPA1 processing and mitochondrial fusion bym-AAA protease isoenzymes and OMA1

(2009) Sarah Ehses et al.   JOURNAL OF CELL BIOLOGY

Inducible proteolytic inactivation of OPA1 mediated by the OMA1 protease in mammalian cells

(2009) Brian Head et al.   JOURNAL OF CELL BIOLOGY

The dynamin-related GTPase Drp1 is required for embryonic and brain development in mice

(2009) Junko Wakabayashi et al.   JOURNAL OF CELL BIOLOGY

Regulation of mitochondrial dynamics in acute kidney injury in cell culture and rodent models

(2009) Craig Brooks et al.   JOURNAL OF CLINICAL INVESTIGATION

Morphological dynamics of mitochondria — A special emphasis on cardiac muscle cells

(2009) Jennifer Hom et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Drosophila Miro Is Required for Both Anterograde and Retrograde Axonal Mitochondrial Transport

(2009) G. J. Russo et al.   JOURNAL OF NEUROSCIENCE

Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice

(2009) Naotada Ishihara et al.   NATURE CELL BIOLOGY

Mitochondrial Dynamics in Mammalian Health and Disease

(2009) Marc Liesa et al.   PHYSIOLOGICAL REVIEWS

Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

(2008) Gilad Twig et al.   EMBO JOURNAL

Shaping mitochondria: The complex posttranslational regulation of the mitochondrial fission protein DRP1

(2008) Ansgar Santel et al.   IUBMB LIFE

GTPase dependent recruitment of Grif-1 by Miro1 regulates mitochondrial trafficking in hippocampal neurons

(2008) Andrew F. MacAskill et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

The Novel Tail-anchored Membrane Protein Mff Controls Mitochondrial and Peroxisomal Fission in Mammalian Cells

(2008) Shilpa Gandre-Babbe et al.   MOLECULAR BIOLOGY OF THE CELL

Mitofusin 2 tethers endoplasmic reticulum to mitochondria

(2008) Olga Martins de Brito et al.   NATURE

Effect of Cyclosporine on Reperfusion Injury in Acute Myocardial Infarction

(2008) Christophe Piot et al.   NEW ENGLAND JOURNAL OF MEDICINE

Dephosphorylation by calcineurin regulates translocation of Drp1 to mitochondria

(2008) G. M. Cereghetti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bidirectional Ca2+-dependent control of mitochondrial dynamics by the Miro GTPase

(2008) M. Saotome et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitofusin 2: A Mitochondria-Shaping Protein with Signaling Roles Beyond Fusion

(2007) Olga Martins de Brito et al.   ANTIOXIDANTS & REDOX SIGNALING