Autism Spectrum Disorder: Signaling Pathways and Prospective Therapeutic Targets
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Title
Autism Spectrum Disorder: Signaling Pathways and Prospective Therapeutic Targets
Authors
Keywords
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Journal
CELLULAR AND MOLECULAR NEUROBIOLOGY
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2020-05-29
DOI
10.1007/s10571-020-00882-7
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Note: Only part of the references are listed.- Update on Drug Management of Refractory Epilepsy in Tuberous Sclerosis Complex
- (2020) Emma van der Poest Clement et al. PEDIATRIC DRUGS
- Identification of FMR1-regulated molecular networks in human neurodevelopment
- (2020) Meng Li et al. GENOME RESEARCH
- Effects of single-dose antipurinergic therapy on behavioral and molecular alterations in the valproic acid-induced animal model of autism
- (2020) Mauro Mozael Hirsch et al. NEUROPHARMACOLOGY
- Vitamin A deficiency increases the risk of gastrointestinal comorbidity and exacerbates core symptoms in children with autism spectrum disorder
- (2020) Boli Cheng et al. PEDIATRIC RESEARCH
- FMRP Control of Ribosome Translocation Promotes Chromatin Modifications and Alternative Splicing of Neuronal Genes Linked to Autism
- (2020) Sneha Shah et al. Cell Reports
- Zinc and Vitamin A Deficiency in a Cohort of Children with Autism Spectrum Disorder
- (2019) Deirdre U. Sweetman et al. CHILD CARE HEALTH AND DEVELOPMENT
- Targeting the crosstalks of Wnt pathway with Hedgehog and Notch for cancer therapy
- (2019) Sharmistha Chatterjee et al. PHARMACOLOGICAL RESEARCH
- The Autism and Angelman Syndrome Protein Ube3A/E6AP: The Gene, E3 Ligase Ubiquitination Targets and Neurobiological Functions
- (2019) Natasha Khatri et al. Frontiers in Molecular Neuroscience
- Retinoic acid signaling pathways
- (2019) Norbert B. Ghyselinck et al. DEVELOPMENT
- Autism-linked dopamine transporter mutation alters striatal dopamine neurotransmission and dopamine-dependent behaviors
- (2019) Gabriella E. DiCarlo et al. JOURNAL OF CLINICAL INVESTIGATION
- Impaired neurodevelopmental pathways in autism spectrum disorder: a review of signaling mechanisms and crosstalk
- (2019) Santosh Kumar et al. Journal of Neurodevelopmental Disorders
- Sonic hedgehog signaling in astrocytes mediates cell type-specific synaptic organization
- (2019) Steven A Hill et al. eLife
- Wnt, Notch, and TGF-β Pathways Impinge on Hedgehog Signaling Complexity: An Open Window on Cancer
- (2019) Maria Pelullo et al. Frontiers in Genetics
- Mutations in the sonic hedgehog pathway cause macrocephaly‐associated conditions due to crosstalk to the PI3K/AKT/mTOR pathway
- (2019) Steven D. Klein et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- Integrating Autism Spectrum Disorder Pathophysiology: Mitochondria, Vitamin A, CD38, Oxytocin, Serotonin and Melatonergic Alterations in the Placenta and Gut
- (2019) Michael Maes et al. CURRENT PHARMACEUTICAL DESIGN
- The use of iPSC technology for modeling Autism Spectrum Disorders
- (2019) Fabiele Baldino Russo et al. NEUROBIOLOGY OF DISEASE
- Hedgehog Signaling: An Achilles’ Heel in Cancer
- (2019) Madiha Niyaz et al. Translational Oncology
- The mTOR Signaling Pathway Activity and Vitamin D Availability Control the Expression of Most Autism Predisposition Genes
- (2019) Ekaterina A. Trifonova et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Inhibition of tyrosine kinase signaling by tyrphostin AG126 downregulates the IL-21/IL-21R and JAK/STAT pathway in the BTBR mouse model of autism
- (2019) Sheikh F. Ahmad et al. NEUROTOXICOLOGY
- Classics in Chemical Neuroscience: Risperidone
- (2018) Trevor C. Chopko et al. ACS Chemical Neuroscience
- Activation of IL-17 receptor leads to increased oxidative inflammation in peripheral monocytes of autistic children
- (2018) Ahmed Nadeem et al. BRAIN BEHAVIOR AND IMMUNITY
- Vitamin A improves the symptoms of autism spectrum disorders and decreases 5-hydroxytryptamine (5-HT): A pilot study
- (2018) Min Guo et al. BRAIN RESEARCH BULLETIN
- A highlight on Sonic hedgehog pathway
- (2018) Gabriela Basile Carballo et al. Cell Communication and Signaling
- Resveratrol attenuates pro-inflammatory cytokines and activation of JAK1-STAT3 in BTBR T + Itpr3 tf /J autistic mice
- (2018) Sheikh F. Ahmad et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Association between SHANK3 polymorphisms and susceptibility to autism spectrum disorder
- (2018) Shuang Qiu et al. GENE
- Pharmacological Inhibition of ERK Signaling Rescues Pathophysiology and Behavioral Phenotype Associated with 16p11.2 Chromosomal Deletion in Mice
- (2018) J. Pucilowska et al. JOURNAL OF NEUROSCIENCE
- Impact of Auditory Integrative Training on Transforming Growth Factor-β1 and Its Effect on Behavioral and Social Emotions in Children with Autism Spectrum Disorder
- (2018) Laila Al-Ayadhi et al. MEDICAL PRINCIPLES AND PRACTICE
- Loss of Angelman Syndrome Protein E6AP Disrupts a Novel Antagonistic Estrogen-Retinoic Acid Transcriptional Crosstalk in Neurons
- (2018) Jimmy El Hokayem et al. MOLECULAR NEUROBIOLOGY
- Vitamin A Deficiency Induces Autistic-Like Behaviors in Rats by Regulating the RARβ-CD38-Oxytocin Axis in the Hypothalamus
- (2018) Xi Lai et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Neuroimmunologic and Neurotrophic Interactions in Autism Spectrum Disorders: Relationship to Neuroinflammation
- (2018) Kshama Ohja et al. NEUROMOLECULAR MEDICINE
- Vitamin A and vitamin D deficiencies exacerbate symptoms in children with autism spectrum disorders
- (2018) Min Guo et al. NUTRITIONAL NEUROSCIENCE
- A Review of Oxytocin and Arginine-Vasopressin Receptors and Their Modulation of Autism Spectrum Disorder
- (2018) Ilaria Cataldo et al. Frontiers in Molecular Neuroscience
- Current Enlightenment About Etiology and Pharmacological Treatment of Autism Spectrum Disorder
- (2018) Nermin Eissa et al. Frontiers in Neuroscience
- Cerebrospinal Fluid Vasopressin and Symptom Severity in Children with Autism
- (2018) Ozge Oztan et al. ANNALS OF NEUROLOGY
- Autism spectrum disorder
- (2018) Catherine Lord et al. LANCET
- Decreased levels of serum retinoic acid in chinese children with autism spectrum disorder
- (2018) Wei Zhou et al. PSYCHIATRY RESEARCH
- Fragile X mental retardation 1 gene enhances the translation of large autism-related proteins
- (2018) Ethan J. Greenblatt et al. SCIENCE
- PI3K Signaling in Neurons: A Central Node for the Control of Multiple Functions
- (2018) Karina Sánchez-Alegría et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- TGF-β1 Restores Hippocampal Synaptic Plasticity and Memory in Alzheimer Model via the PI3K/Akt/Wnt/β-Catenin Signaling Pathway
- (2018) Yueqiang Hu et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- A rare human CEP290 variant disrupts the molecular integrity of the primary cilium and impairs Sonic Hedgehog machinery
- (2018) Michaela B. C. Kilander et al. Scientific Reports
- Autism-associated CHD8 deficiency impairs axon development and migration of cortical neurons
- (2018) Qiong Xu et al. Molecular Autism
- Inhibitory-κB Kinase (IKK) α and Nuclear Factor-κB (NFκB)-Inducing Kinase (NIK) as Anti-Cancer Drug Targets
- (2018) Andrew Paul et al. Cells
- Neurobiological bases of autism-epilepsy comorbidity: a focus on excitation/inhibition imbalance
- (2017) Yuri Bozzi et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Dopamine antagonists for treatment resistance in autism spectrum disorders: review and focus on BDNF stimulators loxapine and amitriptyline
- (2017) Jessica A. Hellings et al. EXPERT OPINION ON PHARMACOTHERAPY
- The extracellular signal-regulated kinase 1/2 pathway in neurological diseases: A potential therapeutic target (Review)
- (2017) Jing Sun et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Autism Symptoms in Fragile X Syndrome
- (2017) Manman Niu et al. JOURNAL OF CHILD NEUROLOGY
- Retinoic acid-related orphan receptor alpha (RORA) variants are associated with autism spectrum disorder
- (2017) Arezou Sayad et al. METABOLIC BRAIN DISEASE
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- (2017) Yunjin Lee et al. MOLECULAR NEUROBIOLOGY
- Targeting sonic hedgehog signaling in neurological disorders
- (2017) Sita Sharan Patel et al. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
- Upregulation of IL-9 and JAK-STAT signaling pathway in children with autism
- (2017) Sheikh F. Ahmad et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Chd8 Mutation Leads to Autistic-like Behaviors and Impaired Striatal Circuits
- (2017) Randall J. Platt et al. Cell Reports
- MeCP2 mutations: progress towards understanding and treating Rett syndrome
- (2017) Ruth R. Shah et al. Genome Medicine
- Ribosomal Protein S6 Phosphorylation Is Involved in Novelty-Induced Locomotion, Synaptic Plasticity and mRNA Translation
- (2017) Emma Puighermanal et al. Frontiers in Molecular Neuroscience
- PI3K/AKT/mTOR Signaling Mediates Valproic Acid-Induced Neuronal Differentiation of Neural Stem Cells through Epigenetic Modifications
- (2017) Xi Zhang et al. Stem Cell Reports
- β-Catenin Directs Nuclear Factor-κB p65 Output via CREB-Binding Protein/p300 in Human Airway Smooth Muscle
- (2017) Tim Koopmans et al. Frontiers in Immunology
- De Novo Mutations of RERE Cause a Genetic Syndrome with Features that Overlap Those Associated with Proximal 1p36 Deletions
- (2016) Brieana Fregeau et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Novel Shank3 mutant exhibits behaviors with face validity for autism and altered striatal and hippocampal function
- (2016) Thomas C. Jaramillo et al. Autism Research
- Proliferation, survival and metabolism: the role of PI3K/AKT/mTOR signalling in pluripotency and cell fate determination
- (2016) Jason S. L. Yu et al. DEVELOPMENT
- Neurofibromatosis type 1 (NF1 ) gene: Beyond café au lait spots and dermal neurofibromas
- (2016) Sirkku Peltonen et al. EXPERIMENTAL DERMATOLOGY
- TGF-β-induced profibrotic signaling is regulated in part by the WNT receptor Frizzled-8
- (2016) Anita I. R. Spanjer et al. FASEB JOURNAL
- Loss of MeCP2 in the rat models regression, impaired sociability and transcriptional deficits of Rett syndrome
- (2016) Surabi Veeraragavan et al. HUMAN MOLECULAR GENETICS
- Deletion of CTNNB1 in inhibitory circuitry contributes to autism-associated behavioral defects
- (2016) Fengping Dong et al. HUMAN MOLECULAR GENETICS
- Wnt signaling networks in autism spectrum disorder and intellectual disability
- (2016) Vickie Kwan et al. Journal of Neurodevelopmental Disorders
- Upstream regulators and downstream effectors of NF-κB in Alzheimer's disease
- (2016) Zhe-Min Shi et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- Dysregulation of Th1, Th2, Th17, and T regulatory cell-related transcription factor signaling in children with autism
- (2016) Sheikh Fayaz Ahmad et al. MOLECULAR NEUROBIOLOGY
- Advancing the understanding of autism disease mechanisms through genetics
- (2016) Luis de la Torre-Ubieta et al. NATURE MEDICINE
- Lessons learned from studying syndromic autism spectrum disorders
- (2016) Yehezkel Sztainberg et al. NATURE NEUROSCIENCE
- Chd8 mediates cortical neurogenesis via transcriptional regulation of cell cycle and Wnt signaling
- (2016) Omer Durak et al. NATURE NEUROSCIENCE
- Molecular and Neural Functions of Rai1 , the Causal Gene for Smith-Magenis Syndrome
- (2016) Wei-Hsiang Huang et al. NEURON
- Wnt signaling in cancer
- (2016) T Zhan et al. ONCOGENE
- Investigation of 7-dehydrocholesterol reductase pathway to elucidate off-target prenatal effects of pharmaceuticals: a systematic review
- (2016) M R Boland et al. PHARMACOGENOMICS JOURNAL
- The maternal interleukin-17a pathway in mice promotes autism-like phenotypes in offspring
- (2016) G. B. Choi et al. SCIENCE
- Relevance of Neuroinflammation and Encephalitis in Autism
- (2016) Janet K. Kern et al. Frontiers in Cellular Neuroscience
- DYRK1B blocks canonical and promotes non-canonical Hedgehog signaling through activation of the mTOR/AKT pathway
- (2016) Rajeev Singh et al. Oncotarget
- Evidence for genetic regulation of mRNA expression of the dosage-sensitive gene retinoic acid induced-1 (RAI1) in human brain
- (2016) Li Chen et al. Scientific Reports
- Atopic diseases and inflammation of the brain in the pathogenesis of autism spectrum disorders
- (2016) T C Theoharides et al. Translational Psychiatry
- Language Impairments in ASD Resulting from a Failed Domestication of the Human Brain
- (2016) Antonio Benítez-Burraco et al. Frontiers in Neuroscience
- Crosstalk between Wnt/β-Catenin and NF-κB Signaling Pathway during Inflammation
- (2016) Bin Ma et al. Frontiers in Immunology
- Pathway Network Analyses for Autism Reveal Multisystem Involvement, Major Overlaps with Other Diseases and Convergence upon MAPK and Calcium Signaling
- (2016) Ya Wen et al. PLoS One
- Therapeutic Effect of a Synthetic RORα/γ Agonist in an Animal Model of Autism
- (2015) Yongjun Wang et al. ACS Chemical Neuroscience
- Crosstalk between Wnt/β-catenin and Hedgehog/Gli signaling pathways in colon cancer and implications for therapy
- (2015) Li Song et al. CANCER BIOLOGY & THERAPY
- Dynamics of the HPA axis and inflammatory cytokines: Insights from mathematical modeling
- (2015) Hamed Malek et al. COMPUTERS IN BIOLOGY AND MEDICINE
- A phase III study of belagenpumatucel-L, an allogeneic tumour cell vaccine, as maintenance therapy for non-small cell lung cancer
- (2015) G. Giaccone et al. EUROPEAN JOURNAL OF CANCER
- Reduced cholesterol levels impair Smoothened activation in Smith–Lemli–Opitz syndrome
- (2015) Robert Blassberg et al. HUMAN MOLECULAR GENETICS
- Autistic spectrum disorders: A review of clinical features, theories and diagnosis
- (2015) Marc Fakhoury INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE
- Inflammatory Cytokines: Potential Biomarkers of Immunologic Dysfunction in Autism Spectrum Disorders
- (2015) Ningan Xu et al. MEDIATORS OF INFLAMMATION
- Balancing Proliferation and Connectivity in PTEN-associated Autism Spectrum Disorder
- (2015) Amanda K. Tilot et al. Neurotherapeutics
- Whole-Exome Sequencing in a South American Cohort Links ALDH1A3, FOXN1 and Retinoic Acid Regulation Pathways to Autism Spectrum Disorders
- (2015) Oscar A. Moreno-Ramos et al. PLoS One
- Plant polyphenols as inhibitors of NF-κB induced cytokine production—a potential anti-inflammatory treatment for Alzheimer's disease?
- (2015) Niloo Karunaweera et al. Frontiers in Molecular Neuroscience
- Ribosomal Protein S6 Phosphorylation in the Nervous System: From Regulation to Function
- (2015) Anne Biever et al. Frontiers in Molecular Neuroscience
- Characterizing autism spectrum disorders by key biochemical pathways
- (2015) Megha Subramanian et al. Frontiers in Neuroscience
- The Impact of Neuroimmune Alterations in Autism Spectrum Disorder
- (2015) Carmem Gottfried et al. Frontiers in Psychiatry
- Mapk/Erk activation in an animal model of social deficits shows a possible link to autism
- (2015) Alireza Faridar et al. Molecular Autism
- Expression in the human brain of retinoic acid induced 1, a protein associated with neurobehavioural disorders
- (2014) Yara Dadalti Fragoso et al. Brain Structure & Function
- Negative regulation of signal transducer and activator of transcription-3 signalling cascade by lupeol inhibits growth and induces apoptosis in hepatocellular carcinoma cells
- (2014) K S Siveen et al. BRITISH JOURNAL OF CANCER
- A review of crosstalk between MAPK and Wnt signals and its impact on cartilage regeneration
- (2014) Ying Zhang et al. CELL AND TISSUE RESEARCH
- Common EIF4E variants modulate risk for autism spectrum disorders in the high-functioning range
- (2014) Regina Waltes et al. JOURNAL OF NEURAL TRANSMISSION
- Can we safely target the WNT pathway?
- (2014) Michael Kahn NATURE REVIEWS DRUG DISCOVERY
- The Implications of Brain Connectivity in the Neuropsychology of Autism
- (2014) Jose O. Maximo et al. NEUROPSYCHOLOGY REVIEW
- Autism, oxytocin and interoception
- (2014) E. Quattrocki et al. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
- Sonic hedgehog signaling in the postnatal brain
- (2014) Arturo Álvarez-Buylla et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Motor neuron derivation from human embryonic and induced pluripotent stem cells: experimental approaches and clinical perspectives
- (2014) Irene Faravelli et al. Stem Cell Research & Therapy
- Overproduction of Upper-Layer Neurons in the Neocortex Leads to Autism-like Features in Mice
- (2014) Wei-Qun Fang et al. Cell Reports
- A pilot controlled trial of insulin-like growth factor-1 in children with Phelan-McDermid syndrome
- (2014) Alexander Kolevzon et al. Molecular Autism
- Exome sequencing of extended families with autism reveals genes shared across neurodevelopmental and neuropsychiatric disorders
- (2014) Holly N Cukier et al. Molecular Autism
- Biomarkers in Autism
- (2014) Andre A. S. Goldani et al. Frontiers in Psychiatry
- Targeting PI3K/Akt/mTOR Signaling in Cancer
- (2014) Camillo Porta et al. Frontiers in Oncology
- The RASopathies
- (2013) Katherine A. Rauen Annual Review of Genomics and Human Genetics
- Activin and TGF-β Effects on Brain Development and Neural Stem Cells
- (2013) Griselda Rodriguez-Martinez et al. CNS & Neurological Disorders-Drug Targets
- Pharmacotherapy for the Core Symptoms in Autistic Disorder: Current Status of the Research
- (2013) Cristan Farmer et al. DRUGS
- Role of Cytokine Signaling during Nervous System Development
- (2013) Alyaa Mousa et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Tissue-Derived Hedgehog Proteins Modulate Th Differentiation and Disease
- (2013) A. L. Furmanski et al. JOURNAL OF IMMUNOLOGY
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- (2013) Meng-Chuan Lai et al. LANCET
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- (2013) Shahid Bashir et al. MEDICAL PRINCIPLES AND PRACTICE
- SHANK3 and IGF1 restore synaptic deficits in neurons from 22q13 deletion syndrome patients
- (2013) Aleksandr Shcheglovitov et al. NATURE
- Age-Dependent Modulation of Synaptic Plasticity and Insulin Mimetic Effect of Lipoic Acid on a Mouse Model of Alzheimer’s Disease
- (2013) Harsh Sancheti et al. PLoS One
- Targeting Wnt-driven cancer through the inhibition of Porcupine by LGK974
- (2013) J. Liu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Wnt signaling in the regulation of adult hippocampal neurogenesis
- (2013) Lorena Varela-Nallar et al. Frontiers in Cellular Neuroscience
- Insulin-like growth factor-1 rescues synaptic and motor deficits in a mouse model of autism and developmental delay
- (2013) Ozlem Bozdagi et al. Molecular Autism
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- (2012) Yan Wang et al. CANCER CELL
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- (2012) Hans Clevers et al. CELL
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- (2012) M. Rhinn et al. DEVELOPMENT
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- (2012) Kuldeep Kumawat et al. FASEB JOURNAL
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- (2012) Afaf El-Ansary et al. Journal of Neuroinflammation
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- (2012) Geraldine Dawson et al. JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY
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- (2012) Peter T. Tsai et al. NATURE
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- (2012) Christof Niehrs NATURE REVIEWS MOLECULAR CELL BIOLOGY
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- (2012) Juan I. Rodriguez et al. Neuron Glia Biology
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- (2012) Suzanne Coghlan et al. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
- Multiplex Targeted Sequencing Identifies Recurrently Mutated Genes in Autism Spectrum Disorders
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- (2011) Brian Magnuson et al. BIOCHEMICAL JOURNAL
- Notch pathway activation can replace the requirement for Wnt4 and Wnt9b in mesenchymal-to-epithelial transition of nephron stem cells
- (2011) S. C. Boyle et al. DEVELOPMENT
- IL-6 is increased in the cerebellum of autistic brain and alters neural cell adhesion, migration and synaptic formation
- (2011) Hongen Wei et al. Journal of Neuroinflammation
- NF-κB Signaling in the Brain of Autistic Subjects
- (2011) Mazhar Malik et al. MEDIATORS OF INFLAMMATION
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- (2011) M. Cargnello et al. MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS
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- (2011) Laila Y. Al-Ayadhi NEUROCHEMICAL RESEARCH
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- (2011) Kirsty Sawicka et al. NEUROPSYCHOPHARMACOLOGY
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- (2011) Usha S. Naik et al. PLoS One
- Plasma Cytokine Profiles in Subjects with High-Functioning Autism Spectrum Disorders
- (2011) Katsuaki Suzuki et al. PLoS One
- The Ras-ERK and PI3K-mTOR pathways: cross-talk and compensation
- (2011) Michelle C. Mendoza et al. TRENDS IN BIOCHEMICAL SCIENCES
- Increased midgestational IFN-γ, IL-4 and IL-5 in women bearing a child with autism: A case-control study
- (2011) Paula E Goines et al. Molecular Autism
- Aberrant NF-KappaB Expression in Autism Spectrum Condition: A Mechanism for Neuroinflammation
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- (2010) Zhongping Wang et al. Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology
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- (2010) Hideki Okamoto et al. BIOLOGICAL PSYCHIATRY
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- (2010) H. Ikeda et al. BLOOD
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- (2010) Paul Ashwood et al. BRAIN BEHAVIOR AND IMMUNITY
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- (2010) Hanne Delbroek et al. EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY
- Global methylation profiling of lymphoblastoid cell lines reveals epigenetic contributions to autism spectrum disorders and a novel autism candidate gene, RORA, whose protein product is reduced in autistic brain
- (2010) AnhThu Nguyen et al. FASEB JOURNAL
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- (2010) Mazhar Malik et al. IMMUNOBIOLOGY
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- (2010) Enzo Emanuele et al. NEUROSCIENCE LETTERS
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- (2010) Yuko Komiya et al. Organogenesis
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- (2009) Bozena Kaminska et al. Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology
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- (2009) Nagako Kawashima et al. CHEMISTRY-A EUROPEAN JOURNAL
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- (2009) Y. Katoh et al. CURRENT MOLECULAR MEDICINE
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- (2009) Kyle M. Sousa et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2009) Ellisa Parker-Athill et al. JOURNAL OF NEUROIMMUNOLOGY
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- (2009) Xiaohong Li et al. JOURNAL OF NEUROIMMUNOLOGY
- Psychiatric Disorders in Children With Autism Spectrum Disorders: Prevalence, Comorbidity, and Associated Factors in a Population-Derived Sample
- (2009) Emily Simonoff et al. JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY
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- (2009) Benjamin Z. Stanton et al. Molecular BioSystems
- Cytokines and CNS Development
- (2009) Benjamin E. Deverman et al. NEURON
- The Nuclear Factor NF- B Pathway in Inflammation
- (2009) T. Lawrence Cold Spring Harbor Perspectives in Biology
- Wnt/Notch signalling and information processing during development
- (2008) P. Hayward et al. DEVELOPMENT
- Decreased transforming growth factor beta1 in autism: A potential link between immune dysregulation and impairment in clinical behavioral outcomes
- (2008) P ASHWOOD et al. JOURNAL OF NEUROIMMUNOLOGY
- Reversal of learning deficits in a Tsc2 +/− mouse model of tuberous sclerosis
- (2008) Dan Ehninger et al. NATURE MEDICINE
- Regression in Autistic Spectrum Disorders
- (2008) Gerry A. Stefanatos NEUROPSYCHOLOGY REVIEW
- Recurrent Rearrangements of Chromosome 1q21.1 and Variable Pediatric Phenotypes
- (2008) Heather C. Mefford et al. NEW ENGLAND JOURNAL OF MEDICINE
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