Motor neuron derivation from human embryonic and induced pluripotent stem cells: experimental approaches and clinical perspectives

The ROCK Inhibitor Y-26732 Enhances the Survival and Proliferation of Human Embryonic Stem Cell-Derived Neural Progenitor Cells upon Dissociation

(2013) Ruttachuk Rungsiwiwut et al.   CELLS TISSUES ORGANS

TARDBPandFUSMutations Associated with Amyotrophic Lateral Sclerosis: Summary and Update

(2013) Serena Lattante et al.   HUMAN MUTATION

Induced neural stem cells (iNSCs) in neurodegenerative diseases

(2013) Andreas Hermann et al.   JOURNAL OF NEURAL TRANSMISSION

Accelerated High-Yield Generation of Limb-Innervating Motor Neurons from Human Stem Cells

(2013) M. W. Amoroso et al.   JOURNAL OF NEUROSCIENCE

Derivation and Expansion Using Only Small Molecules of Human Neural Progenitors for Neurodegenerative Disease Modeling

(2013) Peter Reinhardt et al.   PLoS One

Targeting RNA Foci in iPSC-Derived Motor Neurons from ALS Patients with a C9ORF72 Repeat Expansion

(2013) D. Sareen et al.   Science Translational Medicine

Human conditionally immortalized neural stem cells improve locomotor function after spinal cord injury in the rat

(2013) Takashi Amemori et al.   Stem Cell Research & Therapy

Clinical translation of human neural stem cells

(2013) Ann Tsukamoto et al.   Stem Cell Research & Therapy

Amyotrophic Lateral Sclerosis: An update for 2013 Clinical Features, Pathophysiology, Management and Therapeutic Trials

(2013) Paul Gordon et al.   Aging and Disease

Human induced pluripotent stem cells and neurodegenerative disease

(2012) Yong Wook Jung et al.   CURRENT OPINION IN NEUROLOGY

Disease-specific induced pluripotent stem cells: a platform for human disease modeling and drug discovery

(2012) Jiho Jang et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Defining stem cell types: understanding the therapeutic potential of ESCs, ASCs, and iPS cells

(2012) Clara V Alvarez et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Maturation of Spinal Motor Neurons Derived from Human Embryonic Stem Cells

(2012) Tomonori Takazawa et al.   PLoS One

From Skin Biopsy to Neurons Through a Pluripotent Intermediate Under Good Manufacturing Practice Protocols

(2012) Saravanan Karumbayaram et al.   Stem Cells Translational Medicine

Dysregulation of axonal transport and motorneuron diseases

(2011) Daniela Sau et al.   BIOLOGY OF THE CELL

Downregulation of VAPB expression in motor neurons derived from induced pluripotent stem cells of ALS8 patients

(2011) Miguel Mitne-Neto et al.   HUMAN MOLECULAR GENETICS

Progesterone and 17β-estradiol increase differentiation of mouse embryonic stem cells to motor neurons

(2011) Rodrigo López-González et al.   IUBMB LIFE

Rapid and Efficient Generation of Functional Motor Neurons From Human Pluripotent Stem Cells Using Gene Delivered Transcription Factor Codes

(2011) Mark E Hester et al.   MOLECULAR THERAPY

A functionally characterized test set of human induced pluripotent stem cells

(2011) Gabriella L Boulting et al.   NATURE BIOTECHNOLOGY

Constructing and Deconstructing Stem Cell Models of Neurological Disease

(2011) Steve S.W. Han et al.   NEURON

Expanded GGGGCC Hexanucleotide Repeat in Noncoding Region of C9ORF72 Causes Chromosome 9p-Linked FTD and ALS

(2011) Mariely DeJesus-Hernandez et al.   NEURON

Spinal muscular atrophy

(2011) Adele D'Amico et al.   Orphanet Journal of Rare Diseases

Stem cell technology for the study and treatment of motor neuron diseases

(2011) J Simon Lunn et al.   Regenerative Medicine

Bone Morphogenetic Proteins: A critical review

(2010) Beth Bragdon et al.   CELLULAR SIGNALLING

Specification of Region-Specific Neurons Including Forebrain Glutamatergic Neurons from Human Induced Pluripotent Stem Cells

(2010) Hui Zeng et al.   PLoS One

Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling

(2009) Stuart M Chambers et al.   NATURE BIOTECHNOLOGY

Differentiation of spinal motor neurons from pluripotent human stem cells

(2009) Bao-Yang Hu et al.   Nature Protocols

Survival motor Neuron protein regulates apoptosis in anin vitro model of Spinal muscular atrophy

(2009) Graham C. Parker et al.   NEUROTOXICITY RESEARCH

Highly Efficient Differentiation and Enrichment of Spinal Motor Neurons Derived from Human and Monkey Embryonic Stem Cells

(2009) Tamaki Wada et al.   PLoS One

Directed Differentiation of Human-Induced Pluripotent Stem Cells Generates Active Motor Neurons

(2009) Saravanan Karumbayaram et al.   STEM CELLS

A Targeted Neuroglial Reporter Line Generated by Homologous Recombination in Human Embryonic Stem Cells

(2009) Haipeng Xue et al.   STEM CELLS

Non-Cell-Autonomous Effect of Human SOD1G37R Astrocytes on Motor Neurons Derived from Human Embryonic Stem Cells

(2008) Maria C.N. Marchetto et al.   Cell Stem Cell

Differentiation of Human Embryonic Stem Cells to Regional Specific Neural Precursors in Chemically Defined Medium Conditions

(2008) Slaven Erceg et al.   PLoS One

Induced Pluripotent Stem Cells Generated from Patients with ALS Can Be Differentiated into Motor Neurons

(2008) J. T. Dimos et al.   SCIENCE

Diagnosis and management of motor neurone disease

(2008) Christopher J McDermott et al.   BMJ-British Medical Journal