Detoxification of Mycotoxins through Biotransformation

Developmental Toxicity of Mycotoxin Fumonisin B1 in Animal Embryogenesis: An Overview

(2019) Chompunut Lumsangkul et al.   Toxins

Determination of the absolute configurations of the stereogenic centers of ustilaginoidins by studying the biosynthetic monomers from a gene knockout mutant of Villosiclava virens

(2019) Daowan Lai et al.   Scientific Reports

Review: Biotechnology of mycotoxins detoxification using microorganisms and enzymes

(2019) Fadia Ben Taheur et al.   TOXICON

Ustilobisorbicillinol A, a Cytotoxic Sorbyl-Containing Aromatic Polyketide from Ustilaginoidea virens

(2019) Daowan Lai et al.   ORGANIC LETTERS

Insights into In Vivo Absolute Oral Bioavailability, Biotransformation, and Toxicokinetics of Zearalenone, α-Zearalenol, β-Zearalenol, Zearalenone-14-glucoside, and Zearalenone-14-sulfate in Pigs

(2019) Amelie Catteuw et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Mycotoxin patulin in food matrices: occurrence and its biological degradation strategies

(2019) Marina Sajid et al.   DRUG METABOLISM REVIEWS

The characteristics, occurrence, and toxicological effects of patulin

(2019) Iman Saleh et al.   FOOD AND CHEMICAL TOXICOLOGY

Sorbicillinoids From the Fungus Ustilaginoidea virens and Their Phytotoxic, Cytotoxic, and Antimicrobial Activities

(2019) Jiajia Meng et al.   Frontiers in Chemistry

Detoxification Strategies for Zearalenone Using Microorganisms: A Review

(2019) Nan Wang et al.   Microorganisms

Ustilaginoidin M1, a new bis-naphtho-γ-pyrone from the fungus Villosiclava virens

(2019) Jiajia Meng et al.   NATURAL PRODUCT RESEARCH

Biotransformation of the Mycotoxin Zearalenone to its Metabolites Hydrolyzed Zearalenone (HZEN) and Decarboxylated Hydrolyzed Zearalenone (DHZEN) Diminishes its Estrogenicity In Vitro and In Vivo

(2019) Sebastian Fruhauf et al.   Toxins

Identification and toxicological analysis of products of patulin degradation by Pichia caribbica

(2018) Xiangfeng Zheng et al.   BIOLOGICAL CONTROL

Fumonisins and their analogs in contaminated corn and its processed foods – a review

(2018) Nestor Ponce-García et al.   Food Additives and Contaminants Part A-Chemistry Analysis Control Exposure & Risk Assessment

Sterigmatocystin: A mycotoxin to be seriously considered

(2018) César Horacio Díaz Nieto et al.   FOOD AND CHEMICAL TOXICOLOGY

Zearalenone Uptake and Biotransformation in Micropropagated Triticum durum Desf. Plants: A Xenobolomic Approach

(2018) Enrico Rolli et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Modified Fusarium Mycotoxins in Cereals and Their Products—Metabolism, Occurrence, and Toxicity: An Updated Review

(2018) Marcin Bryła et al.   MOLECULES

Addressing the mycotoxin deoxynivalenol contamination with soil-derived bacterial and enzymatic transformations targeting the C3 carbon

(2018) Y.I. Hassan et al.   World Mycotoxin Journal

Correction to: Glucuronidation of deoxynivalenol (DON) by different animal species: identification of iso-DON glucuronides and iso-deepoxy-DON glucuronides as novel DON metabolites in pigs, rats, mice, and cows

(2018) Heidi E. Schwartz-Zimmermann et al.   ARCHIVES OF TOXICOLOGY

Toxicokinetic profile of fusarenon-X and its metabolite nivalenol in the goat (Capra hircus)

(2018) Wanchalerm Phruksawan et al.   TOXICON

Current major degradation methods for aflatoxins: A review

(2018) Zhao Peng et al.   TRENDS IN FOOD SCIENCE & TECHNOLOGY

Removing and detoxifying methods of patulin: A review

(2018) Enjie Diao et al.   TRENDS IN FOOD SCIENCE & TECHNOLOGY

Isotopic Labeling Studies Reveal the Patulin Detoxification Pathway by the Biocontrol Yeast Rhodotorula kratochvilovae LS11

(2018) Cristina Pinedo et al.   JOURNAL OF NATURAL PRODUCTS

Purification and identification of an aflatoxin B1 degradation enzyme from Pantoea sp. T6

(2018) Yanli Xie et al.   TOXICON

Detoxification of mycotoxin patulin by the yeast Rhodotorula mucilaginosa

(2018) Xiaohong Li et al.   FOOD CONTROL

Aflatoxin B1: A review on metabolism, toxicity, occurrence in food, occupational exposure, and detoxification methods

(2018) Blake R. Rushing et al.   FOOD AND CHEMICAL TOXICOLOGY

Untargeted LC–MS based 13C labelling provides a full mass balance of deoxynivalenol and its degradation products formed during baking of crackers, biscuits and bread

(2018) David Stadler et al.   FOOD CHEMISTRY

Esterase activity inspired selection and characterization of zearalenone degrading bacteria Bacillus pumilus ES-21

(2017) Gang Wang et al.   FOOD CONTROL

New Ustilaginoidins from Rice False Smut Balls Caused by Villosiclava virens and Their Phytotoxic and Cytotoxic Activities

(2017) Weibo Sun et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Detoxification of Fusaric Acid by the Soil Microbe Mucor rouxii

(2017) Frankie K. Crutcher et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Preparation of T-2-glucoronide with Rat Hepatic Microsomes and Its Use along with T-2 for Activation of the JAK/STAT Signaling Pathway in RAW264.7 Cells

(2017) Xing Wang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Biodegradation of ochratoxin A by Alcaligenes faecalis isolated from soil

(2017) H.H. Zhang et al.   JOURNAL OF APPLIED MICROBIOLOGY

The enzymatic epimerization of deoxynivalenol by Devosia mutans proceeds through the formation of 3-keto-DON intermediate

(2017) Yousef I. Hassan et al.   Scientific Reports

Mycotoxin Biotransformation by Native and Commercial Enzymes: Present and Future Perspectives

(2017) Martina Loi et al.   Toxins

Synthesis of Mono- and Di-Glucosides of Zearalenone and α-/β-Zearalenol by Recombinant Barley Glucosyltransferase HvUGT14077

(2017) Herbert Michlmayr et al.   Toxins

Ustiloxin G, a New Cyclopeptide Mycotoxin from Rice False Smut Balls

(2017) Xiaohan Wang et al.   Toxins

Strategies and Methodologies for Developing Microbial Detoxification Systems to Mitigate Mycotoxins

(2017) Yan Zhu et al.   Toxins

Biodegradation and biodetoxification of Fusarium mycotoxins by Sphaerodes mycoparasitica

(2017) Seon Hwa Kim et al.   AMB Express

The enzymatic detoxification of the mycotoxin deoxynivalenol: identification of DepA from the DON epimerization pathway

(2017) Jason Carere et al.   Microbial Biotechnology

Mechanistic Insight into the Biosynthesis and Detoxification of Fumonisin Mycotoxins

(2016) Kevin M. N. Burgess et al.   ACS Chemical Biology

Innovative technologies for the mitigation of mycotoxins in animal feed and ingredients—A review of recent patents

(2016) Yan Zhu et al.   ANIMAL FEED SCIENCE AND TECHNOLOGY

Effects of zearalenone-diet on expression of ghrelin and PCNA genes in ovaries of post-weaning piglets

(2016) Meiling Dai et al.   ANIMAL REPRODUCTION SCIENCE

Toxicology of deoxynivalenol and its acetylated and modified forms

(2016) Delphine Payros et al.   ARCHIVES OF TOXICOLOGY

Patulin transformation products and last intermediates in its biosynthetic pathway, E- and Z-ascladiol, are not toxic to human cells

(2016) Joanna Tannous et al.   ARCHIVES OF TOXICOLOGY

Crystal Structure of Os79 (Os04g0206600) from Oryza sativa: A UDP-glucosyltransferase Involved in the Detoxification of Deoxynivalenol

(2016) Karl M. Wetterhorn et al.   BIOCHEMISTRY

Microbial degradation of aflatoxin B1: Current status and future advances

(2016) C. Verheecke et al.   INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY

Sulfoglucosides as Novel Modified Forms of the Mycotoxins Alternariol and Alternariol Monomethyl Ether

(2016) Sebastian T. Soukup et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Biodegradation of Ochratoxin A by Aspergillus tubingensis Isolated from Meju

(2016) Sung Min Cho et al.   JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY

Enhanced α-Zearalenol Hydrolyzing Activity of a Mycoestrogen-Detoxifying Lactonase by Structure-Based Engineering

(2016) Zhongxia Xu et al.   ACS Catalysis

Gastrointestinal Degradation of Fumonisin B1 by Carboxylesterase FumD Prevents Fumonisin Induced Alteration of Sphingolipid Metabolism in Turkey and Swine

(2016) Sabine Masching et al.   Toxins

Biodegradation of Mycotoxins: Tales from Known and Unexplored Worlds

(2016) Ilse Vanhoutte et al.   Frontiers in Microbiology

Review on microbial degradation of aflatoxins

(2015) O. A. Adebo et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Aerobic and anaerobicin vitrotesting of feed additives claiming to detoxify deoxynivalenol and zearalenone

(2015) Irene Hahn et al.   Food Additives and Contaminants Part A-Chemistry Analysis Control Exposure & Risk Assessment

Detoxification of mycotoxin patulin by the yeast Rhodosporidium paludigenum

(2015) Ruiyu Zhu et al.   FOOD CHEMISTRY

Bioactive Bis-naphtho-γ-pyrones from Rice False Smut Pathogen Ustilaginoidea virens

(2015) Shiqiong Lu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Conjugation of the Mycotoxins Alternariol and Alternariol Monomethyl Ether in Tobacco Suspension Cells

(2015) Andreas A. Hildebrand et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Ultraviolet irradiation detoxification of aflatoxins

(2015) Enjie Diao et al.   TRENDS IN FOOD SCIENCE & TECHNOLOGY

Biochemical Characterization of a Recombinant UDP-glucosyltransferase from Rice and Enzymatic Production of Deoxynivalenol-3-O-β-D-glucoside

(2015) Herbert Michlmayr et al.   Toxins

Metabolomics of the Bio-Degradation Process of Aflatoxin B1 by Actinomycetes at an Initial pH of 6.0

(2015) Manal Eshelli et al.   Toxins

Biological detoxification of mycotoxins: a review

(2014) Amal S. Hathout et al.   ANNALS OF MICROBIOLOGY

Toxicity of the mycotoxin citrinin and its metabolite dihydrocitrinone and of mixtures of citrinin and ochratoxin A in vitro

(2014) Wolfram Föllmann et al.   ARCHIVES OF TOXICOLOGY

Catechol Formation: A Novel Pathway in the Metabolism of Sterigmatocystin and 11-Methoxysterigmatocystin

(2014) Erika Pfeiffer et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Epoxide Reduction to an Alcohol: A Novel Metabolic Pathway for Perylene Quinone-Type Alternaria Mycotoxins in Mammalian Cells

(2014) Stefanie C. Fleck et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Biotransformation of the mycotoxin zearalenone by fungi of the generaRhizopusandAspergillus

(2014) Antje Brodehl et al.   FEMS MICROBIOLOGY LETTERS

Degradation of ochratoxin A byBacillus amyloliquefaciensASAG1

(2014) Xiaojiao Chang et al.   Food Additives and Contaminants Part A-Chemistry Analysis Control Exposure & Risk Assessment

Zearalenone-16-O-glucoside: A New Masked Mycotoxin

(2014) Maria Paula Kovalsky Paris et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Validation of a UHPLC–MS/MS method for quantification of zearalenone, α-zearalenol, β-zearalenol, α-zearalanol, β-zearalanol and zearalanone in human urine

(2014) H. Belhassen et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Reduction of aflatoxin B1 to aflatoxicol: A comprehensive DFT study provides clues to its toxicity

(2014) Sedat Karabulut et al.   JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE

Biodegradation of aflatoxin B1 in contaminated rice straw by Pleurotus ostreatus MTCC 142 and Pleurotus ostreatus GHBBF10 in the presence of metal salts and surfactants

(2014) Arijit Das et al.   WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY

Searching for Genes Responsible for Patulin Degradation in a Biocontrol Yeast Provides Insight into the Basis for Resistance to This Mycotoxin

(2013) G. Ianiri et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Trichothecenes: Structure-Toxic Activity Relationships

(2013) Qinghua Wu et al.   CURRENT DRUG METABOLISM

Detection of masked mycotoxins derived from type A trichothecenes in corn by high-resolution LC-Orbitrap mass spectrometer

(2013) H. Nakagawa et al.   Food Additives and Contaminants Part A-Chemistry Analysis Control Exposure & Risk Assessment

T-2 toxin is hydroxylated by chicken CYP3A37

(2013) Yiyang Yuan et al.   FOOD AND CHEMICAL TOXICOLOGY

Biotransformation of patulin to hydroascladiol by Lactobacillus plantarum

(2013) Sumaiya Hawar et al.   FOOD CONTROL

Degradation and detoxification of aflatoxin B1 by Pseudomonas putida

(2013) Melvin S. Samuel et al.   INTERNATIONAL BIODETERIORATION & BIODEGRADATION

Chicken Cytochrome P450 1A5 Is the Key Enzyme for Metabolizing T-2 Toxin to 3'OH-T-2

(2013) Shufeng Shang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Biotransformation of the Fungal Phytotoxin Fomannoxin by Soil Streptomycetes

(2013) Nadine Horlacher et al.   JOURNAL OF CHEMICAL ECOLOGY

Conversion of Fusaric Acid to Fusarinol by Aspergillus tubingensis: A Detoxification Reaction

(2013) Frankie K. Crutcher et al.   JOURNAL OF CHEMICAL ECOLOGY

Microbial Detoxification of Mycotoxins

(2013) Susan P. McCormick   JOURNAL OF CHEMICAL ECOLOGY

Metabolites from Alternaria Fungi and Their Bioactivities

(2013) Jingfeng Lou et al.   MOLECULES

Glucosylation and Other Biotransformations of T-2 Toxin by Yeasts of the Trichomonascus Clade

(2012) Susan P. McCormick et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Patulin: Mechanism of genotoxicity

(2012) Nina Glaser et al.   FOOD AND CHEMICAL TOXICOLOGY

Masked mycotoxins: A review

(2012) Franz Berthiller et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Molecular interactions of the phytotoxins destruxin B and sirodesmin PL with crucifers and cereals: Metabolism and elicitation of plant defenses

(2012) M. Soledade C. Pedras et al.   PHYTOCHEMISTRY

Effects of mycotoxin-contaminated diets and deactivating compound in laying hens: 2. Effects on white shell egg quality and characteristics

(2012) J. T. Lee et al.   POULTRY SCIENCE

Enzyme characteristics of aminotransferase FumI of Sphingopyxis sp. MTA144 for deamination of hydrolyzed fumonisin B1

(2011) Doris Hartinger et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Biological detoxification of the mycotoxin deoxynivalenol and its use in genetically engineered crops and feed additives

(2011) Petr Karlovsky   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Metabolic Pathways of Ochratoxin A

(2011) Qinghua Wu et al.   CURRENT DRUG METABOLISM

Degradation of Ochratoxin A byBrevibacteriumSpecies

(2011) Hector Rodriguez et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Conversion of the Mycotoxin Patulin to the Less Toxic Desoxypatulinic Acid by the Biocontrol Yeast Rhodosporidium kratochvilovae Strain LS11

(2011) Raffaello Castoria et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

T-2 Toxin, a Trichothecene Mycotoxin: Review of Toxicity, Metabolism, and Analytical Methods

(2011) Yanshen Li et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Aerobic and anaerobic de-epoxydation of mycotoxin deoxynivalenol by bacteria originating from agricultural soil

(2011) Rafiqul Islam et al.   WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY

Accumulation Kinetics of Three Scirpentriol-Based Toxins in Oats Inoculated in Vitro with Isolates of Fusarium sporotrichioides and Fusarium poae

(2011) Margit Schollenberger et al.   Toxins

Observation of T-2 Toxin and HT-2 Toxin Glucosides from Fusarium sporotrichioides by Liquid Chromatography Coupled to Tandem Mass Spectrometry (LC-MS/MS)

(2011) Mark Busman et al.   Toxins

Hydroxylation of the mycotoxin zearalenone at aliphatic positions: novel mammalian metabolites

(2011) Andreas A. Hildebrand et al.   Mycotoxin Research

Nocardioides sp. strain WSN05-2, isolated from a wheat field, degrades deoxynivalenol, producing the novel intermediate 3-epi-deoxynivalenol

(2010) Yoko Ikunaga et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Deoxynivalenol: mechanisms of action, human exposure, and toxicological relevance

(2010) James J. Pestka   ARCHIVES OF TOXICOLOGY

Ozone applications to prevent and degrade mycotoxins: a review

(2010) Otniel Freitas-Silva et al.   DRUG METABOLISM REVIEWS

Metabolic pathways of trichothecenes

(2010) Qinghua Wu et al.   DRUG METABOLISM REVIEWS

Detoxification of aflatoxin B1 by manganese peroxidase from the white-rot fungus Phanerochaete sordida YK-624

(2010) Jianqiao Wang et al.   FEMS MICROBIOLOGY LETTERS

Assessment of deoxynivalenol metabolite profiles in UK adults

(2010) Paul C. Turner et al.   FOOD AND CHEMICAL TOXICOLOGY

Biological degradation of aflatoxins

(2009) Qinghua Wu et al.   DRUG METABOLISM REVIEWS

Degradation of fumonisin B1 by the consecutive action of two bacterial enzymes

(2009) Stefan Heinl et al.   JOURNAL OF BIOTECHNOLOGY

Aromatic hydroxylation is a major metabolic pathway of the mycotoxin zearalenone in vitro

(2009) Erika Pfeiffer et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Enhanced beauvericin production with in situ adsorption in mycelial liquid culture of Fusarium redolens Dzf2

(2009) Li-Jian Xu et al.   PROCESS BIOCHEMISTRY

Chemical and biological transformations for detoxification of trichothecene mycotoxins in human and animal food chains: a review

(2009) Jianwei He et al.   TRENDS IN FOOD SCIENCE & TECHNOLOGY

Aflatoxin B1 detoxification by CYP321A1 inHelicoverpa zea

(2008) Guodong Niu et al.   ARCHIVES OF INSECT BIOCHEMISTRY AND PHYSIOLOGY

Emerging Fusarium -Mycotoxins Fusaproliferin, Beauvericin, Enniatins, And Moniliformin—A Review

(2008) Marika Jestoi   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

The TRI101 story: engineering wheat and barley to resist Fusarium head blight

(2008) N. Alexander   World Mycotoxin Journal

Microbial transformation of trichothecene mycotoxins

(2008) T. Zhou et al.   World Mycotoxin Journal

Reduction in ochratoxin A levels in white wine, following treatment with activated carbon and sodium bentonite

(2007) Işıl Var et al.   FOOD CONTROL