Development of a vaccine against Staphylococcus aureus invasive infections: Evidence based on human immunity, genetics and bacterial evasion mechanisms
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Development of a vaccine against Staphylococcus aureus invasive infections: Evidence based on human immunity, genetics and bacterial evasion mechanisms
Authors
Keywords
-
Journal
FEMS MICROBIOLOGY REVIEWS
Volume 44, Issue 1, Pages 123-153
Publisher
Oxford University Press (OUP)
Online
2019-12-14
DOI
10.1093/femsre/fuz030
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Identification of biologic agents to neutralize the bicomponent leukocidins of Staphylococcus aureus
- (2019) Rita Chan et al. Science Translational Medicine
- Vital Signs: Epidemiology and Recent Trends in Methicillin-Resistant and in Methicillin-Susceptible Staphylococcus aureus Bloodstream Infections — United States
- (2019) Athena P. Kourtis et al. MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT
- Considering the ‘Alternatives’ for Next-Generation Anti-Staphylococcus aureus Vaccine Development
- (2019) Eóin C. O’Brien et al. TRENDS IN MOLECULAR MEDICINE
- A Subset of Type I Conventional Dendritic Cells Controls Cutaneous Bacterial Infections through VEGFα-Mediated Recruitment of Neutrophils
- (2019) Baptiste Janela et al. IMMUNITY
- Metabolic Adaptation in MRSA Pneumonia
- (2019) Stanislaw J. Gabryszewski et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Penetration of a Monoclonal Antibody Combination (ASN100) Targeting S. aureus Cytotoxins in Lung Epithelial Lining Fluid: A Randomized, Double-blind, Placebo-controlled, Single Ascending Dose Study in Healthy Volunteers.
- (2019) Zoltan Magyarics et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Resistin-like Molecule α Provides Vitamin-A-Dependent Antimicrobial Protection in the Skin
- (2019) Tamia A. Harris et al. Cell Host & Microbe
- The prevalence of Staphylococcus aureus with mucoid phenotype in the airways of patients with cystic fibrosis—A prospective study
- (2019) Farina E. Lennartz et al. INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY
- Clonal Vγ6+Vδ4+ T cells promote IL-17–mediated immunity against Staphylococcus aureus skin infection
- (2019) Mark C. Marchitto et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Panton–Valentine leucocidin is the key determinant of Staphylococcus aureus pyomyositis in a bacterial GWAS
- (2019) Bernadette C Young et al. eLife
- IL-1β and IL-10 Host Responses in Patients with Staphylococcus aureus Bacteremia Determined by Antimicrobial Therapy
- (2019) Cecilia F Volk et al. CLINICAL INFECTIOUS DISEASES
- MAIT cells as attractive vaccine targets
- (2019) A. Michael Downey et al. FEBS LETTERS
- Loss of the interleukin-6 receptor causes immunodeficiency, atopy, and abnormal inflammatory responses
- (2019) Sarah Spencer et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Rational Design of Toxoid Vaccine Candidates for Staphylococcus aureus Leukocidin AB (LukAB)
- (2019) Shweta Kailasan et al. Toxins
- The biology and functional importance of MAIT cells
- (2019) Dale I. Godfrey et al. NATURE IMMUNOLOGY
- Bacterial Colonization, Overgrowth, and Superinfection in Atopic Dermatitis
- (2018) Stephanie M. Rangel et al. CLINICS IN DERMATOLOGY
- Safety and tolerability of a single administration of AR-301, a human monoclonal antibody, in ICU patients with severe pneumonia caused by Staphylococcus aureus: first-in-human trial
- (2018) Bruno François et al. INTENSIVE CARE MEDICINE
- Clonally expanded γδ T cells protect against Staphylococcus aureus skin reinfection
- (2018) Carly A. Dillen et al. JOURNAL OF CLINICAL INVESTIGATION
- Staphylococcus aureus and Atopic Dermatitis: A Complex and Evolving Relationship
- (2018) Joan A. Geoghegan et al. TRENDS IN MICROBIOLOGY
- Integrated BioTherapeutics
- (2018) M. Javad Aman Human Vaccines & Immunotherapeutics
- Factors Influencing Functional Heterogeneity in Human Mucosa-Associated Invariant T Cells
- (2018) Joana Dias et al. Frontiers in Immunology
- Atopic dermatitis
- (2018) Stephan Weidinger et al. Nature Reviews Disease Primers
- Human CD45 is an F-component-specific receptor for the staphylococcal toxin Panton–Valentine leukocidin
- (2018) Angelino T. Tromp et al. Nature Microbiology
- Serologic Detection of Antibodies Targeting the Leukocidin LukAB Strongly Predicts Staphylococcus aureus in Children With Invasive Infection
- (2018) James B Wood et al. Journal of the Pediatric Infectious Diseases Society
- A prognostic model of persistent bacteremia and mortality in complicated S. aureus bloodstream infection
- (2018) Alessander O Guimaraes et al. CLINICAL INFECTIOUS DISEASES
- Start a fire, kill the bug: The role of platelets in inflammation and infection
- (2018) Carsten Deppermann et al. Innate Immunity
- Survival following bloodstream infection; a prospective multinational cohort study assessing the impact of place of care
- (2018) Kate Nambiar et al. JOURNAL OF INFECTION
- Biology and management of methicillin resistant Staphylococcus aureus in cystic fibrosis
- (2018) Nour Akil et al. PEDIATRIC PULMONOLOGY
- Innate T cells in the intensive care unit
- (2018) Edy Yong Kim et al. MOLECULAR IMMUNOLOGY
- Human genetic variation in GLS2 is associated with development of complicated Staphylococcus aureus bacteremia
- (2018) William K. Scott et al. PLoS Genetics
- Humoral immune consequences of Staphylococcus aureus ST239-associated bacteremia
- (2017) H. Ghasemzadeh-Moghaddam et al. EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
- Evaluating genetic susceptibility to Staphylococcus aureus bacteremia in African Americans using admixture mapping
- (2017) D D Cyr et al. GENES AND IMMUNITY
- A biallelic mutation in IL6ST encoding the GP130 co-receptor causes immunodeficiency and craniosynostosis
- (2017) Tobias Schwerd et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Genetic diversity of pvl- positive community-onset methicillin-resistant Staphylococcus aureus isolated at a university hospital in Japan
- (2017) Hidemasa Nakaminami et al. JOURNAL OF INFECTION AND CHEMOTHERAPY
- Monoclonal Antibodies Against the Staphylococcus aureus Bicomponent Leukotoxin AB Isolated Following Invasive Human Infection Reveal Diverse Binding and Modes of Action
- (2017) Isaac P. Thomsen et al. JOURNAL OF INFECTIOUS DISEASES
- Lethal CD4 T Cell Responses Induced by Vaccination Against Staphylococcus aureus Bacteremia
- (2017) Hatice Karauzum et al. JOURNAL OF INFECTIOUS DISEASES
- Neutrophil extracellular traps and the dysfunctional innate immune response of cystic fibrosis lung disease: a review
- (2017) Sheonagh M. Law et al. Journal of Inflammation-London
- Leukocidins: staphylococcal bi-component pore-forming toxins find their receptors
- (2017) András N. Spaan et al. NATURE REVIEWS MICROBIOLOGY
- Staphylococcus aureus and Staphylococcus epidermidis strain diversity underlying pediatric atopic dermatitis
- (2017) Allyson L. Byrd et al. Science Translational Medicine
- Staphylococcus aureus pore-forming toxins: The interface of pathogen and host complexity
- (2017) E. Sachiko Seilie et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Delayed neutrophil apoptosis enhances NET formation in cystic fibrosis
- (2017) Robert D Gray et al. THORAX
- MAIT cells launch a rapid, robust and distinct hyperinflammatory response to bacterial superantigens and quickly acquire an anergic phenotype that impedes their cognate antimicrobial function: Defining a novel mechanism of superantigen-induced immunopathology and immunosuppression
- (2017) Christopher R. Shaler et al. PLOS BIOLOGY
- Antigen delivery to dendritic cells shapes human CD4+ and CD8+ T cell memory responses to Staphylococcus aureus
- (2017) Julia Uebele et al. PLoS Pathogens
- Panton-Valentine Leucocidin (PVL) as a Potential Indicator for Prevalence, Duration, and Severity of Staphylococcus aureus Osteomyelitis
- (2017) Bei Jiang et al. Frontiers in Microbiology
- The Impact of the Staphylococcus aureus Virulome on Infection in a Developing Country: A Cohort Study
- (2017) Marthe Lebughe et al. Frontiers in Microbiology
- Staphylococcal protein Ecb impairs complement receptor-1 mediated recognition of opsonized bacteria
- (2017) Hanne Amdahl et al. PLoS One
- Risk and outcomes of methicillin-resistant Staphylococcus aureus (MRSA) bacteremia among patients admitted with and without MRSA nares colonization
- (2016) Natalie S. Marzec et al. AMERICAN JOURNAL OF INFECTION CONTROL
- Safety, Tolerability, and Pharmacokinetics of MEDI4893, an Investigational, Extended-Half-Life, Anti-Staphylococcus aureus Alpha-Toxin Human Monoclonal Antibody, in Healthy Adults
- (2016) Xiang-Qing Yu et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Factors associated with severity in invasive community-acquired Staphylococcus aureus infections in children: a prospective European multicentre study
- (2016) M. Gijón et al. CLINICAL MICROBIOLOGY AND INFECTION
- Diabetes and risk of community-acquiredStaphylococcus aureusbacteremia: a population-based case–control study
- (2016) Jesper Smit et al. EUROPEAN JOURNAL OF ENDOCRINOLOGY
- Host response to Staphylococcus aureus cytotoxins in children with cystic fibrosis
- (2016) Ashley D. Chadha et al. Journal of Cystic Fibrosis
- Staphylococcus aureusvaccines: Deviating from the carol
- (2016) Dominique Missiakas et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Increased in vitro phenol-soluble modulin production is associated with soft tissue infection source in clinical isolates of methicillin-susceptible Staphylococcus aureus
- (2016) Robert Qi et al. JOURNAL OF INFECTION
- Ratio of T-Helper Type 1 (Th1) to Th17 Cytokines in Whole Blood Is Associated With Human β-Defensin 3 Expression in Skin and PersistentStaphylococcus aureusNasal Carriage
- (2016) Dennis Nurjadi et al. JOURNAL OF INFECTIOUS DISEASES
- Staphylococcusaureusα-Toxin Response Distinguishes Respiratory Virus–Methicillin-ResistantS. aureusCoinfection in Children
- (2016) Karl O. A. Yu et al. JOURNAL OF INFECTIOUS DISEASES
- The Staphylococcus aureus polysaccharide capsule and Efb-dependent fibrinogen shield act in concert to protect against phagocytosis
- (2016) Annemarie Kuipers et al. MICROBIOLOGY-SGM
- Presence of the Panton-Valentine Leukocidin Genes in Methicillin-Resistant Staphylococcus aureus Is Associated with Severity and Clinical Outcome of Hospital-Acquired Pneumonia in a Single Center Study in China
- (2016) Chuanling Zhang et al. PLoS One
- Genetic, immunological, and clinical features of patients with bacterial and fungal infections due to inherited IL-17RA deficiency
- (2016) Romain Lévy et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- IVIG-mediated protection against necrotizing pneumonia caused by MRSA
- (2016) Binh An Diep et al. Science Translational Medicine
- Memory γδ T Cells–Newly Appreciated Protagonists in Infection and Immunity
- (2016) Stephen J. Lalor et al. TRENDS IN IMMUNOLOGY
- Status of vaccine research and development of vaccines for Staphylococcus aureus
- (2016) Birgitte K. Giersing et al. VACCINE
- MRSA Infections in HIV-Infected People Are Associated with Decreased MRSA-Specific Th1 Immunity
- (2016) Netanya S. Utay et al. PLoS Pathogens
- Dynamic in vivo mutations within the ica operon during persistence of Staphylococcus aureus in the airways of cystic fibrosis patients
- (2016) Bianca Schwartbeck et al. PLoS Pathogens
- Delta Hemolysin and Phenol-Soluble Modulins, but Not Alpha Hemolysin or Panton-Valentine Leukocidin, Induce Mast Cell Activation
- (2016) Elisabeth Hodille et al. Frontiers in Cellular and Infection Microbiology
- HLA-DR polymorphisms influencein vivoresponses to staphylococcal toxic shock syndrome toxin-1 in a transgenic mouse model
- (2016) A. Krogman et al. HLA
- Community-Associated Methicillin-ResistantStaphylococcus aureusNecrotizing Pneumonia without Evidence of Antecedent Viral Upper Respiratory Infection
- (2016) Cristina Moran Toro et al. Canadian Journal of Infectious Diseases & Medical Microbiology
- One Dose of Staphylococcus aureus 4C-Staph Vaccine Formulated with a Novel TLR7-Dependent Adjuvant Rapidly Protects Mice through Antibodies, Effector CD4+ T Cells, and IL-17A
- (2016) Francesca Mancini et al. PLoS One
- Factors Associated with Worse Lung Function in Cystic Fibrosis Patients with Persistent Staphylococcus aureus
- (2016) Sibylle Junge et al. PLoS One
- Pathogenesis of Staphylococcus aureus Abscesses
- (2015) Scott D. Kobayashi et al. AMERICAN JOURNAL OF PATHOLOGY
- Staphylococcus aureusHemolysin A Disrupts Cell–Matrix Adhesions in Human Airway Epithelial Cells
- (2015) Ina Hermann et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- The Immunobiology of Interleukin-27
- (2015) Hiroki Yoshida et al. Annual Review of Immunology
- Synergistic Action of Staphylococcus aureus α-Toxin on Platelets and Myeloid Lineage Cells Contributes to Lethal Sepsis
- (2015) Michael E. Powers et al. Cell Host & Microbe
- Staphylococcus aureus Infections: Epidemiology, Pathophysiology, Clinical Manifestations, and Management
- (2015) Steven Y. C. Tong et al. CLINICAL MICROBIOLOGY REVIEWS
- A Diagnostic Serum Antibody Test for Patients With Staphylococcus aureus Osteomyelitis
- (2015) Kohei Nishitani et al. CLINICAL ORTHOPAEDICS AND RELATED RESEARCH
- A Dysregulated Balance of Proinflammatory and Anti-Inflammatory Host Cytokine Response Early During Therapy Predicts Persistence and Mortality in Staphylococcus aureus Bacteremia
- (2015) Emi Minejima et al. CRITICAL CARE MEDICINE
- Secondary antibody deficiencies
- (2015) Fatima Dhalla et al. Current Opinion in Allergy and Clinical Immunology
- Host factors that contribute to recurrent staphylococcal skin infection
- (2015) Christopher P. Montgomery et al. CURRENT OPINION IN INFECTIOUS DISEASES
- Th17 Cell Pathway in Human Immunity: Lessons from Genetics and Therapeutic Interventions
- (2015) Dhavalkumar D. Patel et al. IMMUNITY
- Nonredundant Roles of Interleukin-17A (IL-17A) and IL-22 in Murine Host Defense against Cutaneous and Hematogenous Infection Due to Methicillin-Resistant Staphylococcus aureus
- (2015) Liana C. Chan et al. INFECTION AND IMMUNITY
- Polymorphisms in HLA Class II Genes Are Associated With Susceptibility toStaphylococcus aureusInfection in a White Population
- (2015) Gerald N. DeLorenze et al. JOURNAL OF INFECTIOUS DISEASES
- Vaccine composition formulated with a novel TLR7-dependent adjuvant induces high and broad protection againstStaphylococcus aureus
- (2015) Fabio Bagnoli et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Dermal adipocytes protect against invasive Staphylococcus aureus skin infection
- (2015) L.-j. Zhang et al. SCIENCE
- Complex host genetic susceptibility to Staphylococcus aureus infections
- (2015) Sanjay K. Shukla et al. TRENDS IN MICROBIOLOGY
- Increased Susceptibility of Humanized NSG Mice to Panton-Valentine Leukocidin and Staphylococcus aureus Skin Infection
- (2015) Ching Wen Tseng et al. PLoS Pathogens
- Memory Th1 Cells Are Protective in Invasive Staphylococcus aureus Infection
- (2015) Aisling F. Brown et al. PLoS Pathogens
- Staphylococcus aureus Leukocidin A/B (LukAB) Kills Human Monocytes via Host NLRP3 and ASC when Extracellular, but Not Intracellular
- (2015) Jason H. Melehani et al. PLoS Pathogens
- Co-detection of Panton-Valentine leukocidin encoding genes and cotrimoxazole resistance in Staphylococcus aureus in Gabon: implications for HIV-patients’ care
- (2015) Christian Kraef et al. Frontiers in Microbiology
- Antibodies to S. aureus LukS-PV Attenuated Subunit Vaccine Neutralize a Broad Spectrum of Canonical and Non-Canonical Bicomponent Leukotoxin Pairs
- (2015) Rajan P. Adhikari et al. PLoS One
- Cytokine responses to Staphylococcus aureusbloodstream infection differ between patient cohorts that have different clinical courses of infection
- (2014) Sinead McNicholas et al. BMC INFECTIOUS DISEASES
- A genome-wide association study of variants associated with acquisition of Staphylococcus aureus bacteremia in a healthcare setting
- (2014) Charlotte L Nelson et al. BMC INFECTIOUS DISEASES
- Where does a Staphylococcus aureus vaccine stand?
- (2014) V.G. Fowler et al. CLINICAL MICROBIOLOGY AND INFECTION
- Staphylococcal superantigens interact with multiple host receptors to cause serious diseases
- (2014) Christopher S. Stach et al. IMMUNOLOGIC RESEARCH
- Protective Immunity against Recurrent Staphylococcus aureus Skin Infection Requires Antibody and Interleukin-17A
- (2014) Christopher P. Montgomery et al. INFECTION AND IMMUNITY
- Ventilator-associated pneumonia: present understanding and ongoing debates
- (2014) Girish B. Nair et al. INTENSIVE CARE MEDICINE
- Clinical Management ofStaphylococcus aureusBacteremia
- (2014) Thomas L. Holland et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Mouse models for infectious diseases caused by Staphylococcus aureus
- (2014) Hwan Keun Kim et al. JOURNAL OF IMMUNOLOGICAL METHODS
- IFN- Regulated Chemokine Production Determines the Outcome of Staphylococcus aureus Infection
- (2014) R. M. McLoughlin et al. JOURNAL OF IMMUNOLOGY
- Staphylococcus aureus Infection of Mice Expands a Population of Memory T Cells That Are Protective against Subsequent Infection
- (2014) A. G. Murphy et al. JOURNAL OF IMMUNOLOGY
- A Staphylococcus aureus TIR Domain Protein Virulence Factor Blocks TLR2-Mediated NF-κB Signaling
- (2014) Fatemeh Askarian et al. Journal of Innate Immunity
- Models matter: the search for an effective Staphylococcus aureus vaccine
- (2014) Wilmara Salgado-Pabón et al. NATURE REVIEWS MICROBIOLOGY
- Kineret®/IL-1ra Blocks the IL-1/IL-8 Inflammatory Cascade during Recombinant Panton Valentine Leukocidin-Triggered Pneumonia but Not during S. aureus Infection
- (2014) Delphine Labrousse et al. PLoS One
- A Spaetzle-like role for nerve growth factor in vertebrate immunity to Staphylococcus aureus
- (2014) L. Hepburn et al. SCIENCE
- The staphylococcal toxins γ-haemolysin AB and CB differentially target phagocytes by employing specific chemokine receptors
- (2014) András N. Spaan et al. Nature Communications
- Mortality among recipients of the Merck V710 Staphylococcus aureus vaccine after postoperative S. aureus infections: An analysis of possible contributing host factors
- (2014) Tessie B McNeely et al. Human Vaccines & Immunotherapeutics
- Staphylococcal Bicomponent Pore-Forming Toxins: Targets for Prophylaxis and Immunotherapy
- (2014) M. Aman et al. Toxins
- Applying Convergent Immunity to Innovative Vaccines Targeting Staphylococcus aureus
- (2014) Michael R. Yeaman et al. Frontiers in Immunology
- Genome wide association study of SNP-, gene-, and pathway-based approaches to identify genes influencing susceptibility to Staphylococcus aureus infections
- (2014) Zhan Ye et al. Frontiers in Genetics
- Neutrophils Versus Staphylococcus aureus: A Biological Tug of War
- (2013) András N. Spaan et al. Annual Review of Microbiology
- Staphylococcus aureus Leukotoxin ED Targets the Chemokine Receptors CXCR1 and CXCR2 to Kill Leukocytes and Promote Infection
- (2013) Tamara Reyes-Robles et al. Cell Host & Microbe
- The Staphylococcal Toxin Panton-Valentine Leukocidin Targets Human C5a Receptors
- (2013) András N. Spaan et al. Cell Host & Microbe
- A Serologic Correlate of Protective Immunity Against Community-Onset Staphylococcus aureus Infection
- (2013) Stephanie A. Fritz et al. CLINICAL INFECTIOUS DISEASES
- Staphylococcal and Streptococcal Superantigen Exotoxins
- (2013) A. R. Spaulding et al. CLINICAL MICROBIOLOGY REVIEWS
- Staphylococcus aureussubverts cutaneous defense byd-alanylation of teichoic acids
- (2013) Maren Simanski et al. EXPERIMENTAL DERMATOLOGY
- Specific MAIT cell behaviour among innate-like T lymphocytes in critically ill patients with severe infections
- (2013) David Grimaldi et al. INTENSIVE CARE MEDICINE
- Effect of an Investigational Vaccine for Preventing Staphylococcus aureus Infections After Cardiothoracic Surgery
- (2013) Vance G. Fowler et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- The Pattern Recognition Receptor NOD2 Mediates Staphylococcus aureus –Induced IL-17C Expression in Keratinocytes
- (2013) Sarah A. Roth et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Staphylococcus δ-toxin induces allergic skin disease by activating mast cells
- (2013) Yuumi Nakamura et al. NATURE
- Phenol-soluble modulins and staphylococcal infection
- (2013) Andreas Peschel et al. NATURE REVIEWS MICROBIOLOGY
- Adhesion, invasion and evasion: the many functions of the surface proteins of Staphylococcus aureus
- (2013) Timothy J. Foster et al. NATURE REVIEWS MICROBIOLOGY
- Expression of Panton-Valentine Leukocidin mRNA among Staphylococcus aureus Isolates Associates with Specific Clinical Presentations
- (2013) Fangyou Yu et al. PLoS One
- Staphylococcus aureus LukAB cytotoxin kills human neutrophils by targeting the CD11b subunit of the integrin Mac-1
- (2013) A. L. DuMont et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Staphylococcus aureus α-Toxin: Nearly a Century of Intrigue
- (2013) Bryan Berube et al. Toxins
- Cross-talk between Staphylococcus aureus leukocidins-intoxicated macrophages and lung epithelial cells triggers chemokine secretion in an inflammasome-dependent manner
- (2012) Magali Perret et al. CELLULAR MICROBIOLOGY
- Challenges for a Universal Staphylococcus aureus Vaccine
- (2012) R. A. Proctor CLINICAL INFECTIOUS DISEASES
- The Clinical Significance of Vancomycin Minimum Inhibitory Concentration in Staphylococcus aureus Infections: A Systematic Review and Meta-analysis
- (2012) S. J. van Hal et al. CLINICAL INFECTIOUS DISEASES
- Methicillin resistance is not a predictor of severity in community-acquired Staphylococcus aureus necrotizing pneumonia—results of a prospective observational study
- (2012) N. Sicot et al. CLINICAL MICROBIOLOGY AND INFECTION
- Predictors of Mortality in Staphylococcus aureus Bacteremia
- (2012) S. J. van Hal et al. CLINICAL MICROBIOLOGY REVIEWS
- Experimental and natural infections in MyD88- and IRAK-4-deficient mice and humans
- (2012) Horst von Bernuth et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Temporal shifts in the skin microbiome associated with disease flares and treatment in children with atopic dermatitis
- (2012) H. H. Kong et al. GENOME RESEARCH
- The Antimicrobial Protein REG3A Regulates Keratinocyte Proliferation and Differentiation after Skin Injury
- (2012) Yuping Lai et al. IMMUNITY
- Lower Antibody Levels to Staphylococcus aureus Exotoxins Are Associated With Sepsis in Hospitalized Adults With Invasive S. aureus Infections
- (2012) R. P. Adhikari et al. JOURNAL OF INFECTIOUS DISEASES
- Elevated Serum Interleukin-10 at Time of Hospital Admission Is Predictive of Mortality in Patients With Staphylococcus aureus Bacteremia
- (2012) Warren E. Rose et al. JOURNAL OF INFECTIOUS DISEASES
- ADAM10 Mediates Vascular Injury Induced by Staphylococcus aureus α-Hemolysin
- (2012) Michael E. Powers et al. JOURNAL OF INFECTIOUS DISEASES
- Staphylococcus aureus Panton-Valentine leukocidin induces an inflammatory response in human phagocytes via the NLRP3 inflammasome
- (2012) Dirk Holzinger et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Evasion of Toll-like receptor 2 activation by staphylococcal superantigen-like protein 3
- (2012) B. W. Bardoel et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Selective induction of antimicrobial peptides from keratinocytes by staphylococcal bacteria
- (2012) Rie Ommori et al. MICROBIAL PATHOGENESIS
- Complement regulator C4BP binds to Staphylococcus aureus and decreases opsonization
- (2012) Pamela S. Hair et al. MOLECULAR IMMUNOLOGY
- CCR5 is a receptor for Staphylococcus aureus leukotoxin ED
- (2012) Francis Alonzo III et al. NATURE
- Pathogen-induced human TH17 cells produce IFN-γ or IL-10 and are regulated by IL-1β
- (2012) Christina E. Zielinski et al. NATURE
- Cystic fibrosis: a mucosal immunodeficiency syndrome
- (2012) Taylor Sitarik Cohen et al. NATURE MEDICINE
- Panton-Valentine Leukocidin Is Not the Primary Determinant of Outcome for Staphylococcus aureus Skin Infections: Evaluation from the CANVAS Studies
- (2012) Amy Tong et al. PLoS One
- Alpha-Toxin Induces Programmed Cell Death of Human T cells, B cells, and Monocytes during USA300 Infection
- (2012) Tyler K. Nygaard et al. PLoS One
- Effects of Acupuncture at Taixi Acupoint (KI3) on Kidney Proteome
- (2011) Chun-Ri Li et al. AMERICAN JOURNAL OF CHINESE MEDICINE
- Infection, Inflammation, and Lung Function Decline in Infants with Cystic Fibrosis
- (2011) Naveen Pillarisetti et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- The Th17 Pathway in Cystic Fibrosis Lung Disease
- (2011) Hui-Leng Tan et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Human TLRs and IL-1Rs in Host Defense: Natural Insights from Evolutionary, Epidemiological, and Clinical Genetics
- (2011) Jean-Laurent Casanova et al. Annual Review of Immunology
- Severity of Disease and Clinical Outcomes in Patients With Hospital-Acquired Pneumonia Due to Methicillin-Resistant Staphylococcus aureus Strains Not Influenced by the Presence of the Panton-Valentine Leukocidin Gene
- (2011) P. Peyrani et al. CLINICAL INFECTIOUS DISEASES
- Progress Toward a Staphylococcus aureus Vaccine
- (2011) R. S. Daum et al. CLINICAL INFECTIOUS DISEASES
- Infectious Diseases in Patients with IRAK-4, MyD88, NEMO, or I B Deficiency
- (2011) C. Picard et al. CLINICAL MICROBIOLOGY REVIEWS
- Skin-Resident Murine Dendritic Cell Subsets Promote Distinct and Opposing Antigen-Specific T Helper Cell Responses
- (2011) Botond Z. Igyártó et al. IMMUNITY
- Infection of Polarized Airway Epithelial Cells by Normal and Small-Colony Variant Strains of Staphylococcus aureus Is Increased in Cells with Abnormal Cystic Fibrosis Transmembrane Conductance Regulator Function and Is Influenced by NF-κB
- (2011) Gabriel Mitchell et al. INFECTION AND IMMUNITY
- Frequency of Panton-Valentine Leukocidin-Producing Methicillin-Sensitive Staphylococcus Strains in Patients with Complicated Skin and Soft Tissue Infection in Bronx, New York
- (2011) A. Kaltsas et al. JOURNAL OF CLINICAL MICROBIOLOGY
- Presence of Genes Encoding Panton-Valentine Leukocidin Is Not the Primary Determinant of Outcome in Patients with Hospital-Acquired Pneumonia Due to Staphylococcus aureus
- (2011) B. K. Sharma-Kuinkel et al. JOURNAL OF CLINICAL MICROBIOLOGY
- Predictors of Relapse of Methicillin-Resistant Staphylococcus aureus Bacteremia after Treatment with Vancomycin
- (2011) K. J. Welsh et al. JOURNAL OF CLINICAL MICROBIOLOGY
- Panton Valentine Leukocidin Exotoxin Has No Effect on the Outcome of Cancer Patients With Methicillin-Resistant Staphylococcus aureus (MRSA) Infections
- (2011) Marcela Campo et al. MEDICINE
- A Staphylococcus aureus pore-forming toxin subverts the activity of ADAM10 to cause lethal infection in mice
- (2011) Ichiro Inoshima et al. NATURE MEDICINE
- Modern management of primary B-cell immunodeficiencies
- (2011) Miriam Hoernes et al. PEDIATRIC ALLERGY AND IMMUNOLOGY
- Staphylococcus aureus Pneumonia in Children in the Era of Community-acquired Methicillin-resistance at Texas Childrenʼs Hospital
- (2011) Maria A. Carrillo-Marquez et al. PEDIATRIC INFECTIOUS DISEASE JOURNAL
- Staphylococcal Panton-Valentine Leucocidin as a Major Virulence Factor Associated to Furuncles
- (2011) Lamine Baba-Moussa et al. PLoS One
- Chronic Mucocutaneous Candidiasis in Humans with Inborn Errors of Interleukin-17 Immunity
- (2011) A. Puel et al. SCIENCE
- Development of a vaccine against Staphylococcus aureus
- (2011) Brad Spellberg et al. Seminars in Immunopathology
- A history of Panton-Valentine leukocidin (PVL)-associated infection protects against death in PVL-associated pneumonia
- (2011) Jean-Philippe Rasigade et al. VACCINE
- Is there a future for a Staphylococcus aureus vaccine?
- (2011) Richard A. Proctor VACCINE
- Recent advances in the understanding of genetic defects of neutrophil number and function
- (2010) Gerben Bouma et al. BRITISH JOURNAL OF HAEMATOLOGY
- Human Formyl Peptide Receptor 2 Senses Highly Pathogenic Staphylococcus aureus
- (2010) Dorothee Kretschmer et al. Cell Host & Microbe
- Community-Associated Methicillin-Resistant Staphylococcus aureus: Epidemiology and Clinical Consequences of an Emerging Epidemic
- (2010) M. Z. David et al. CLINICAL MICROBIOLOGY REVIEWS
- Progression to bacteremia in critical care patients colonized with methicillin-resistant Staphylococcus aureus expressing Panton–Valentine leukocidin
- (2010) Kevin P. Blaine et al. DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE
- Differences between methicillin-resistant Staphylococcus aureus bacteremic isolates harboring type IV and type V staphylococcal cassette chromosome mec genes based on prior patient healthcare exposure
- (2010) S.-Y. Chen et al. EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
- Clinical and laboratory features of invasive community-onset methicillin-resistant Staphylococcus aureus infection: a prospective case–control study
- (2010) M. C. Wehrhahn et al. EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
- Antibody responses in patients with invasive Staphylococcus aureus infections
- (2010) G. Jacobsson et al. EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
- Trends and Causes of Hospitalizations Among HIV-Infected Persons During the Late HAART Era: What Is the Impact of CD4 Counts and HAART Use?
- (2010) Nancy F Crum-Cianflone et al. JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
- Association Between Respiratory Tract Methicillin-Resistant Staphylococcus aureus and Survival in Cystic Fibrosis
- (2010) Elliott C. Dasenbrook JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Incidence, Risk Factors, and Outcomes of Panton-Valentine Leukocidin-Positive Methicillin-Susceptible Staphylococcus aureus Infections in Auckland, New Zealand
- (2010) S. Muttaiyah et al. JOURNAL OF CLINICAL MICROBIOLOGY
- Clinical Characteristics, Outcomes, and Microbiologic Features Associated with Methicillin-ResistantStaphylococcus aureusBacteremia in Pediatric Patients Treated with Vancomycin
- (2010) Kerry J. Welsh et al. JOURNAL OF CLINICAL MICROBIOLOGY
- Clinical Correlates of Panton‐Valentine Leukocidin (PVL), PVL Isoforms, and Clonal Complex in theStaphylococcus aureusPopulation of Northern Australia
- (2010) Steven Y. C. Tong et al. JOURNAL OF INFECTIOUS DISEASES
- Subcutaneous Infection with S. aureus in Mice Reveals Association of Resistance with Influx of Neutrophils and Th2 Response
- (2010) Nadine Nippe et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- An association of TLR2-16934A>T polymorphism and severity/phenotype of atopic dermatitis
- (2010) DP Potaczek et al. JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
- Clinical Features and Outcome of Patients With IRAK-4 and MyD88 Deficiency
- (2010) Capucine Picard et al. MEDICINE
- Characterization of a new cytotoxin that contributes to Staphylococcus aureus pathogenesis
- (2010) Ashley L. DuMont et al. MOLECULAR MICROBIOLOGY
- Staphylococcal Peptidoglycan Co-Localizes with Nod2 and TLR2 and Activates Innate Immune Response via Both Receptors in Primary Murine Keratinocytes
- (2010) Maria Anna Müller-Anstett et al. PLoS One
- Polymorphonuclear leukocytes mediate Staphylococcus aureus Panton-Valentine leukocidin-induced lung inflammation and injury
- (2010) B. A. Diep et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Staphylococcus aureus Panton-Valentine Leukocidin Is a Very Potent Cytotoxic Factor for Human Neutrophils
- (2010) Bettina Löffler et al. PLoS Pathogens
- Impaired neutrophil migration and phagocytosis in IRAK-4 deficiency
- (2009) Gerben Bouma et al. BRITISH JOURNAL OF HAEMATOLOGY
- Primary Skin Abscesses Are Mainly Caused by Panton-Valentine Leukocidin-Positive Staphylococcus aureus Strains
- (2009) Pascal del Giudice et al. DERMATOLOGY
- Molecular epidemiological analysis of methicillin-resistant Staphylococcus aureus isolates from Chinese pediatric patients
- (2009) W. Zhang et al. EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
- Towards the immune proteome of Staphylococcus aureus – The anti-S. aureus antibody response
- (2009) Silva Holtfreter et al. INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY
- Community-Associated Methicillin-Resistant Staphylococcus aureus Isolated in Finland in 2004 to 2006
- (2009) M. Kanerva et al. JOURNAL OF CLINICAL MICROBIOLOGY
- Presence of Genes Encoding the Panton-Valentine Leukocidin Exotoxin Is Not the Primary Determinant of Outcome in Patients with Complicated Skin and Skin Structure Infections Due to Methicillin-Resistant Staphylococcus aureus: Results of a Multinational Trial
- (2009) I.-G. Bae et al. JOURNAL OF CLINICAL MICROBIOLOGY
- Molecular explanation for the contradiction between systemic Th17 defect and localized bacterial infection in hyper-IgE syndrome
- (2009) Yoshiyuki Minegishi et al. JOURNAL OF EXPERIMENTAL MEDICINE
- A Critical Role for Hemolysins and Bacterial Lipoproteins in Staphylococcus aureus-Induced Activation of the Nlrp3 Inflammasome
- (2009) R. Munoz-Planillo et al. JOURNAL OF IMMUNOLOGY
- Community‐Associated Strains of Methicillin‐ResistantStaphylococcus aureusand Methicillin‐SusceptibleS. aureusin Indigenous Northern Australia: Epidemiology and Outcomes
- (2009) Steven Y. C. Tong et al. JOURNAL OF INFECTIOUS DISEASES
- Factors Predicting and Reducing Mortality in Patients with Invasive Staphylococcus aureus Disease in a Developing Country
- (2009) Emma K. Nickerson et al. PLoS One
- Staphylococcus aureus α-Hemolysin Activates the NLRP3-Inflammasome in Human and Mouse Monocytic Cells
- (2009) Robin R. Craven et al. PLoS One
- The antioxidant role of thiocyanate in the pathogenesis of cystic fibrosis and other inflammation-related diseases
- (2009) Y. Xu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Th1-Th17 Cells Mediate Protective Adaptive Immunity against Staphylococcus aureus and Candida albicans Infection in Mice
- (2009) Lin Lin et al. PLoS Pathogens
- Immunological Mechanisms Underlying the Genetic Predisposition to Severe Staphylococcus aureus Infection in the Mouse Model
- (2008) Maren von Köckritz-Blickwede et al. AMERICAN JOURNAL OF PATHOLOGY
- Staphylococcus aureus Community-Acquired Pneumonia During the 2006 to 2007 Influenza Season
- (2008) Alexander J. Kallen et al. ANNALS OF EMERGENCY MEDICINE
- Different bacterial gene expression patterns and attenuated host immune responses are associated with the evolution of low-level vancomycin resistance during persistent methicillin-resistant Staphylococcus aureus bacteraemia
- (2008) Benjamin P Howden et al. BMC MICROBIOLOGY
- Complex Molecular Epidemiology of Methicillin-Resistant Staphylococcus aureus Isolates From Children With Cystic Fibrosis in the Era of Epidemic Community-Associated Methicillin-Resistant S aureus
- (2008) Daniel Glikman et al. CHEST
- Superantigen Profile ofStaphylococcus aureusIsolates from Patients with Steroid‐Resistant Atopic Dermatitis
- (2008) Patrick M. Schlievert et al. CLINICAL INFECTIOUS DISEASES
- Methicillin-resistant Staphylococcus aureus (MRSA) in hospitalized children: correlation of molecular analysis with clinical presentation and antibiotic susceptibility testing (ABST) results
- (2008) N. Abdel-Haq et al. EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
- Methicillin-susceptible, non-multiresistant methicillin-resistant and multiresistant methicillin-resistant Staphylococcus aureus infections: a clinical, epidemiological and microbiological comparative study
- (2008) W. J. Munckhof et al. EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
- Novel signal transducer and activator of transcription 3 (STAT3) mutations, reduced TH17 cell numbers, and variably defective STAT3 phosphorylation in hyper-IgE syndrome
- (2008) Ellen D. Renner et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Interaction of Human Complement with Sbi, a Staphylococcal Immunoglobulin-binding Protein
- (2008) Julia D. Burman et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Associations between the Genotypes of Staphylococcus aureus Bloodstream Isolates and Clinical Characteristics and Outcomes of Bacteremic Patients
- (2008) T. Lalani et al. JOURNAL OF CLINICAL MICROBIOLOGY
- Deficiency of Th17 cells in hyper IgE syndrome due to mutations inSTAT3
- (2008) Cindy S. Ma et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Methicillin-sensitive Staphylococcus aureus bacteraemia and endocarditis among injection drug users and nonaddicts: Host factors, microbiological and serological characteristics
- (2008) Eeva Ruotsalainen et al. JOURNAL OF INFECTION
- Panton‐Valentine Leukocidin Is Not a Virulence Determinant in Murine Models of Community‐Associated Methicillin‐ResistantStaphylococcus aureusDisease
- (2008) Juliane Bubeck Wardenburg et al. JOURNAL OF INFECTIOUS DISEASES
- Impaired TH17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome
- (2008) Joshua D. Milner et al. NATURE
- Staphylococcus aureus skin/soft-tissue infections: The impact of SCCmec type and Panton-Valentine leukocidin
- (2008) Houssein Jahamy et al. SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES
- Pyogenic Bacterial Infections in Humans with MyD88 Deficiency
- (2008) H. von Bernuth et al. SCIENCE
- A Cholesterol Biosynthesis Inhibitor Blocks Staphylococcus aureus Virulence
- (2008) C.-I Liu et al. SCIENCE
- S. aureus IgG-binding proteins SpA and Sbi: Host specificity and mechanisms of immune complex formation
- (2007) Karen L. Atkins et al. MOLECULAR IMMUNOLOGY
- Clinical features, epidemiology, antimicrobial resistance, and exotoxin genes (including that of Panton–Valentine leukocidin) of gentamicinsusceptible methicillin-resistant Staphylococcus aureus (GS-MRSA) isolated at a paediatric teaching hospital in New South Wales, Australia
- (2007) Jonathan B. Gubbay et al. PATHOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation