Staphylococcus aureus Leukocidin A/B (LukAB) Kills Human Monocytes via Host NLRP3 and ASC when Extracellular, but Not Intracellular
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Title
Staphylococcus aureus Leukocidin A/B (LukAB) Kills Human Monocytes via Host NLRP3 and ASC when Extracellular, but Not Intracellular
Authors
Keywords
Staphylococcus aureus, Monocytes, Toxins, Cell death, Flow cytometry, Secretion, Inflammasomes, Necrotic cell death
Journal
PLoS Pathogens
Volume 11, Issue 6, Pages e1004970
Publisher
Public Library of Science (PLoS)
Online
2015-06-13
DOI
10.1371/journal.ppat.1004970
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Note: Only part of the references are listed.- Neutrophil IL-1β Processing Induced by Pneumolysin Is Mediated by the NLRP3/ASC Inflammasome and Caspase-1 Activation and Is Dependent on K+Efflux
- (2015) Mausita Karmakar et al. JOURNAL OF IMMUNOLOGY
- Structure-Function Analysis of Heterodimer Formation, Oligomerization, and Receptor Binding of theStaphylococcus aureusBi-component Toxin LukGH
- (2014) Adriana Badarau et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Localization and Functionality of the Inflammasome in Neutrophils
- (2014) Martina Bakele et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Bicomponent Pore-Forming Leucocidins of Staphylococcus aureus
- (2014) Francis Alonzo et al. MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS
- Evolution of hypervirulence by a MRSA clone through acquisition of a transposable element
- (2014) Meredith A. Benson et al. MOLECULAR MICROBIOLOGY
- Staphylococcus aureus Leukotoxin ED Targets the Chemokine Receptors CXCR1 and CXCR2 to Kill Leukocytes and Promote Infection
- (2013) Tamara Reyes-Robles et al. Cell Host & Microbe
- The Staphylococcal Toxin Panton-Valentine Leukocidin Targets Human C5a Receptors
- (2013) András N. Spaan et al. Cell Host & Microbe
- K+ Efflux Is the Common Trigger of NLRP3 Inflammasome Activation by Bacterial Toxins and Particulate Matter
- (2013) Raúl Muñoz-Planillo et al. IMMUNITY
- Staphylococcus aureus Elaborates Leukocidin AB To Mediate Escape from within Human Neutrophils
- (2013) Ashley L. DuMont et al. INFECTION AND IMMUNITY
- Children with Invasive Staphylococcus aureus Disease Exhibit a Potently Neutralizing Antibody Response to the Cytotoxin LukAB
- (2013) Isaac P. Thomsen et al. INFECTION AND IMMUNITY
- Identification of a Crucial Residue Required for Staphylococcus aureus LukAB Cytotoxicity and Receptor Recognition
- (2013) Ashley L. DuMont et al. INFECTION AND IMMUNITY
- Activation of caspase-1 by the NLRP3 inflammasome regulates the NADPH oxidase NOX2 to control phagosome function
- (2013) Anna Sokolovska et al. NATURE IMMUNOLOGY
- Staphylococcus aureus LukAB cytotoxin kills human neutrophils by targeting the CD11b subunit of the integrin Mac-1
- (2013) A. L. DuMont et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cell targeting by the Staphylococcus aureus pore-forming toxins: it's not just about lipids
- (2013) Ashley L. DuMont et al. TRENDS IN MICROBIOLOGY
- Is Prolonged Low-Dose Glucocorticoid Treatment Beneficial in Community-Acquired Pneumonia?
- (2013) Marco Confalonieri et al. Current Infectious Disease Reports
- Abscess Formation and Alpha-Hemolysin Induced Toxicity in a Mouse Model of Staphylococcus aureus Peritoneal Infection
- (2012) Sabine Rauch et al. INFECTION AND IMMUNITY
- Rot and SaeRS Cooperate To Activate Expression of the Staphylococcal Superantigen-Like Exoproteins
- (2012) M. A. Benson et al. JOURNAL OF BACTERIOLOGY
- Staphylococcus aureus Leukotoxin GH Promotes Inflammation
- (2012) Natalia Malachowa et al. JOURNAL OF INFECTIOUS DISEASES
- Staphylococcus aureus α-Hemolysin Mediates Virulence in a Murine Model of Severe Pneumonia Through Activation of the NLRP3 Inflammasome
- (2012) Chahnaz Kebaier et al. JOURNAL OF INFECTIOUS DISEASES
- Staphylococcus aureus Panton-Valentine leukocidin induces an inflammatory response in human phagocytes via the NLRP3 inflammasome
- (2012) Dirk Holzinger et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Neutrophil-derived IL-1β Is Sufficient for Abscess Formation in Immunity against Staphylococcus aureus in Mice
- (2012) John S. Cho et al. PLoS Pathogens
- The Inflammasome NLRs in Immunity, Inflammation, and Associated Diseases
- (2011) Beckley K. Davis et al. Annual Review of Immunology
- The NLRP3/ASC/Caspase-1 axis regulates IL-1β processing in neutrophils
- (2011) Arun K. Mankan et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- The inflammasome: an integrated view
- (2011) Olaf Gross et al. IMMUNOLOGICAL REVIEWS
- K+Efflux Is Required for Histone H3 Dephosphorylation by Listeria monocytogenes Listeriolysin O and Other Pore-Forming Toxins
- (2011) Mélanie Anne Hamon et al. INFECTION AND IMMUNITY
- Caspase-1 Protein Induces Apoptosis-associated Speck-like Protein Containing a Caspase Recruitment Domain (ASC)-mediated Necrosis Independently of Its Catalytic Activity
- (2011) Kou Motani et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Inflammasome activation and IL-1β/IL-18 processing are influenced by distinct pathways in microglia
- (2011) Richa Hanamsagar et al. JOURNAL OF NEUROCHEMISTRY
- Panton-Valentine Leukocidin Does Play a Role in the Early Stage of Staphylococcus aureus Skin Infections: A Rabbit Model
- (2011) Urszula Lipinska et al. PLoS One
- Listeria monocytogenes Triggers AIM2-Mediated Pyroptosis upon Infrequent Bacteriolysis in the Macrophage Cytosol
- (2010) John-Demian Sauer et al. Cell Host & Microbe
- The Role of the Inflammasome in Nonmyeloid Cells
- (2010) Amir S. Yazdi et al. JOURNAL OF CLINICAL IMMUNOLOGY
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- (2010) Adam D. Kennedy et al. JOURNAL OF INFECTIOUS DISEASES
- Characterization of a new cytotoxin that contributes to Staphylococcus aureus pathogenesis
- (2010) Ashley L. DuMont et al. MOLECULAR MICROBIOLOGY
- Identification of a Novel Staphylococcus aureus Two-Component Leukotoxin Using Cell Surface Proteomics
- (2010) Christy L. Ventura et al. PLoS One
- Polymorphonuclear leukocytes mediate Staphylococcus aureus Panton-Valentine leukocidin-induced lung inflammation and injury
- (2010) B. A. Diep et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Staphylococcus aureus Panton-Valentine Leukocidin Is a Very Potent Cytotoxic Factor for Human Neutrophils
- (2010) Bettina Löffler et al. PLoS Pathogens
- A Critical Role for Hemolysins and Bacterial Lipoproteins in Staphylococcus aureus-Induced Activation of the Nlrp3 Inflammasome
- (2009) R. Munoz-Planillo et al. JOURNAL OF IMMUNOLOGY
- Major cell death pathways at a glance
- (2009) Linde Duprez et al. MICROBES AND INFECTION
- Pyroptosis: host cell death and inflammation
- (2009) Tessa Bergsbaken et al. NATURE REVIEWS MICROBIOLOGY
- Panton–Valentine Leukocidin Enhances the Severity of Community-Associated Methicillin-Resistant Staphylococcus aureus Rabbit Osteomyelitis
- (2009) Anne-Claude Crémieux et al. PLoS One
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- (2009) Ching Wen Tseng et al. PLoS One
- Staphylococcus aureus α-Hemolysin Activates the NLRP3-Inflammasome in Human and Mouse Monocytic Cells
- (2009) Robin R. Craven et al. PLoS One
- Panton‐Valentine Leukocidin Is Not a Virulence Determinant in Murine Models of Community‐Associated Methicillin‐ResistantStaphylococcus aureusDisease
- (2008) Juliane Bubeck Wardenburg et al. JOURNAL OF INFECTIOUS DISEASES
- Contribution of Panton-Valentine Leukocidin in Community-Associated Methicillin-Resistant Staphylococcus aureus Pathogenesis
- (2008) Binh An Diep et al. PLoS One
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