Ventilator-associated pneumonia: present understanding and ongoing debates

Electronic Implementation of a Novel Surveillance Paradigm for Ventilator-associated Events. Feasibility and Validation

(2014) Peter M. C. Klein Klouwenberg et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Tigecycline use in critically ill patients: a multicentre prospective observational study in the intensive care setting

(2014) Philippe Montravers et al.   INTENSIVE CARE MEDICINE

Randomized Phase 2 Trial To Evaluate the Clinical Efficacy of Two High-Dosage Tigecycline Regimens versus Imipenem-Cilastatin for Treatment of Hospital-Acquired Pneumonia

(2013) Julio Ramirez et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The Clinical Impact and Preventability of Ventilator-Associated Conditions in Critically Ill Patients Who Are Mechanically Ventilated

(2013) John Muscedere et al.   CHEST

Short- vs Long-Duration Antibiotic Regimens for Ventilator-Associated Pneumonia

(2013) George Dimopoulos et al.   CHEST

Is a Strategy Based on Routine Endotracheal Cultures the Best Way to Prescribe Antibiotics in Ventilator-Associated Pneumonia?

(2013) Carlos M. Luna et al.   CHEST

Early Antibiotic Discontinuation in Patients With Clinically Suspected Ventilator-Associated Pneumonia and Negative Quantitative Bronchoscopy Cultures*

(2013) Kirthana Raman et al.   CRITICAL CARE MEDICINE

Linezolid versus vancomycin or teicoplanin for nosocomial pneumonia: meta-analysis of randomised controlled trials

(2013) H. Jiang et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Potentially resistant microorganisms in intubated patients with hospital-acquired pneumonia: the interaction of ecology, shock and risk factors

(2013) Ignacio Martin-Loeches et al.   INTENSIVE CARE MEDICINE

De-escalation of empirical therapy is associated with lower mortality in patients with severe sepsis and septic shock

(2013) J. Garnacho-Montero et al.   INTENSIVE CARE MEDICINE

Clinical outcomes of Pseudomonas aeruginosa pneumonia in intensive care unit patients

(2013) Mario Tumbarello et al.   INTENSIVE CARE MEDICINE

Effect of Early vs Late Tracheostomy Placement on Survival in Patients Receiving Mechanical Ventilation

(2013) Duncan Young et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

National Trauma Institute prospective evaluation of the ventilator bundle in trauma patients

(2013) Martin A. Croce et al.   Journal of Trauma and Acute Care Surgery

Comparison of the Bacterial Etiology of Early-Onset and Late-Onset Ventilator-Associated Pneumonia in Subjects Enrolled in 2 Large Clinical Studies

(2013) M. I. Restrepo et al.   Respiratory Care

Treatment of hospital-acquired pneumonia with linezolid or vancomycin: a systematic review and meta-analysis

(2013) Andre C Kalil et al.   BMJ Open

Inadequate treatment of ventilator-associated and hospital-acquired pneumonia: Risk factors and impact on outcomes

(2012) Nihal Piskin et al.   BMC INFECTIOUS DISEASES

Toward Improved Surveillance: The Impact of Ventilator-Associated Complications on Length of Stay and Antibiotic Use in Patients in Intensive Care Units

(2012) Yoshiro Hayashi et al.   CLINICAL INFECTIOUS DISEASES

Rapid and Reproducible Surveillance for Ventilator-Associated Pneumonia

(2012) M. Klompas et al.   CLINICAL INFECTIOUS DISEASES

Linezolid in Methicillin-Resistant Staphylococcus aureus Nosocomial Pneumonia: A Randomized, Controlled Study

(2012) R. G. Wunderink et al.   CLINICAL INFECTIOUS DISEASES

Continuous Infusion of Beta-Lactam Antibiotics in Severe Sepsis: A Multicenter Double-Blind, Randomized Controlled Trial

(2012) J. M. Dulhunty et al.   CLINICAL INFECTIOUS DISEASES

Objective surveillance definitions for ventilator-associated pneumonia*

(2012) Michael Klompas et al.   CRITICAL CARE MEDICINE

Implementation of Clinical Practice Guidelines for Ventilator-Associated Pneumonia

(2012) Tasnim Sinuff et al.   CRITICAL CARE MEDICINE

Is a ventilator-associated pneumonia rate of zero really possible?

(2012) Michael Klompas   CURRENT OPINION IN INFECTIOUS DISEASES

Ventilator-associated pneumonia and its prevention

(2012) Lila Bouadma et al.   CURRENT OPINION IN INFECTIOUS DISEASES

Value of lower respiratory tract surveillance cultures to predict bacterial pathogens in ventilator-associated pneumonia: systematic review and diagnostic test accuracy meta-analysis

(2012) Nele Brusselaers et al.   INTENSIVE CARE MEDICINE

Use of the clinical pulmonary infection score to guide therapy for ventilator-associated pneumonia risks antibiotic overexposure in patients with trauma

(2012) Nancy A. Parks et al.   Journal of Trauma and Acute Care Surgery

Early-Onset Ventilator-Associated Pneumonia in Adults Randomized Clinical Trial: Comparison of 8 versus 15 Days of Antibiotic Treatment

(2012) Gilles Capellier et al.   PLoS One

National Healthcare Safety Network (NHSN) report, data summary for 2009, device-associated module

(2011) Margaret A. Dudeck et al.   AMERICAN JOURNAL OF INFECTION CONTROL

Nebulized Ceftazidime and Amikacin in Ventilator-associated Pneumonia Caused byPseudomonas aeruginosa

(2011) Qin Lu et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

De-Escalation Therapy: Is It Valuable for the Management of Ventilator-Associated Pneumonia?

(2011) Michael S. Niederman et al.   CLINICS IN CHEST MEDICINE

Reducing ventilator-associated pneumonia in intensive care: Impact of implementing a care bundle*

(2011) Andrew Conway Morris et al.   CRITICAL CARE MEDICINE

Outcomes in patients infected with carbapenem-resistant Acinetobacter baumannii and treated with tigecycline alone or in combination therapy

(2011) R. Guner et al.   INFECTION

BAY41-6551 achieves bactericidal tracheal aspirate amikacin concentrations in mechanically ventilated patients with Gram-negative pneumonia

(2011) Michael S. Niederman et al.   INTENSIVE CARE MEDICINE

Implementation of guidelines for management of possible multidrug-resistant pneumonia in intensive care: an observational, multicentre cohort study

(2011) Daniel H Kett et al.   LANCET INFECTIOUS DISEASES

Multicenter Evaluation of a Novel Surveillance Paradigm for Complications of Mechanical Ventilation

(2011) Michael Klompas et al.   PLoS One

Nosocomial Pneumonia in the Intensive Care Unit Acquired by Mechanically Ventilated versus Nonventilated Patients

(2010) Mariano Esperatti et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Ventilator-Associated Tracheobronchitis in a Mixed Surgical and Medical ICU Population

(2010) John Dallas et al.   CHEST

Linezolid vs Glycopeptide Antibiotics for the Treatment of Suspected Methicillin-Resistant Staphylococcus aureus Nosocomial Pneumonia

(2010) Allan J. Walkey et al.   CHEST

Validation of the American Thoracic Society–Infectious Diseases Society of America Guidelines for Hospital‐Acquired Pneumonia in the Intensive Care Unit

(2010) Miquel Ferrer et al.   CLINICAL INFECTIOUS DISEASES

Ventilator‐Associated Pneumonia: The Clinical Pulmonary Infection Score as a Surrogate for Diagnostics and Outcome

(2010) Marya D. Zilberberg et al.   CLINICAL INFECTIOUS DISEASES

Microbial Etiologies of Hospital‐Acquired Bacterial Pneumonia and Ventilator‐Associated Bacterial Pneumonia

(2010) Ronald N. Jones   CLINICAL INFECTIOUS DISEASES

Linezolid versus vancomycin or teicoplanin for nosocomial pneumonia: A systematic review and meta-analysis*

(2010) Andre C. Kalil et al.   CRITICAL CARE MEDICINE

Early combination antibiotic therapy yields improved survival compared with monotherapy in septic shock: A propensity-matched analysis*

(2010) Anand Kumar et al.   CRITICAL CARE MEDICINE

Comparison of tigecycline with imipenem/cilastatin for the treatment of hospital-acquired pneumonia

(2010) Antonio T. Freire et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

Early vs Late Tracheotomy for Prevention of Pneumonia in Mechanically Ventilated Adult ICU Patients

(2010) Pier Paolo Terragni et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Use of procalcitonin to reduce patients' exposure to antibiotics in intensive care units (PRORATA trial): a multicentre randomised controlled trial

(2010) Lila Bouadma et al.   LANCET

Early- and Late-Onset Pneumonia: Is This Still a Useful Classification?

(2009) P. Gastmeier et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Empiric antibiotic therapy for suspected ventilator-associated pneumonia: A systematic review and meta-analysis of randomized trials

(2009) Mary-Anne W. Aarts et al.   CRITICAL CARE MEDICINE

Randomized trial of combination versus monotherapy for the empiric treatment of suspected ventilator-associated pneumonia*

(2009) Daren K. Heyland et al.   CRITICAL CARE MEDICINE

Procalcitonin for reduced antibiotic exposure in ventilator-associated pneumonia: a randomised study

(2009) D. Stolz et al.   EUROPEAN RESPIRATORY JOURNAL

Pharmacodynamic-based clinical pathway for empiric antibiotic choice in patients with ventilator-associated pneumonia

(2009) Anthony M. Nicasio et al.   JOURNAL OF CRITICAL CARE

CDC/NHSN surveillance definition of health care–associated infection and criteria for specific types of infections in the acute care setting

(2008) Teresa C. Horan et al.   AMERICAN JOURNAL OF INFECTION CONTROL

Prophylaxis of Ventilator-Associated Pneumonia

(2008) Donald E. Craven et al.   CHEST

Ventilator-Associated Tracheobronchitis

(2008) Donald E. Craven et al.   CHEST

Early tracheotomy versus prolonged endotracheal intubation in unselected severely ill ICU patients

(2008) François Blot et al.   INTENSIVE CARE MEDICINE

Comprehensive evidence-based clinical practice guidelines for ventilator-associated pneumonia: Diagnosis and treatment

(2008) John Muscedere et al.   JOURNAL OF CRITICAL CARE

Sequential measurements of procalcitonin levels in diagnosing ventilator-associated pneumonia

(2007) P. Ramirez et al.   EUROPEAN RESPIRATORY JOURNAL