Molecular explanation for the contradiction between systemic Th17 defect and localized bacterial infection in hyper-IgE syndrome

Differential Roles of Interleukin-17A and -17F in Host Defense against Mucoepithelial Bacterial Infection and Allergic Responses

(2009) Harumichi Ishigame et al.   IMMUNITY

The roles of IL-17A in inflammatory immune responses and host defense against pathogens

(2009) Yoichiro Iwakura et al.   IMMUNOLOGICAL REVIEWS

Genetic origins of hyper-IgE syndrome

(2008) Yoshiyuki Minegishi et al.   CURRENT ALLERGY AND ASTHMA REPORTS

Cytokines that regulate autoimmunity

(2008) Caroline Diveu et al.   CURRENT OPINION IN IMMUNOLOGY

The Biological Functions of T Helper 17 Cell Effector Cytokines in Inflammation

(2008) Wenjun Ouyang et al.   IMMUNITY

Defects in Jak-STAT-mediated cytokine signals cause hyper-IgE syndrome: lessons from a primary immunodeficiency

(2008) Y. Minegishi et al.   INTERNATIONAL IMMUNOLOGY

Novel signal transducer and activator of transcription 3 (STAT3) mutations, reduced TH17 cell numbers, and variably defective STAT3 phosphorylation in hyper-IgE syndrome

(2008) Ellen D. Renner et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Deficiency of Th17 cells in hyper IgE syndrome due to mutations inSTAT3

(2008) Cindy S. Ma et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Mutations inSTAT3andIL12RB1impair the development of human IL-17–producing T cells

(2008) Ludovic de Beaucoudrey et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Impaired TH17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome

(2008) Joshua D. Milner et al.   NATURE

IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia

(2008) Shean J Aujla et al.   NATURE MEDICINE

Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens

(2008) Yan Zheng et al.   NATURE MEDICINE