Article
Microbiology
Utta Helbig, Constance Riemschneider, Guido Werner, Nancy Kriebel, Franziska Layer-Nicolaou
Summary: In Saxony, Germany, the detection of PVL-positive MRSA must be reported to the local health authority, which then takes appropriate measures to control the infection. Isolates from 2019 cases were analyzed, and various MRSA lineages with PVL were identified. Most cases were skin and soft-tissue infections and had a history of travel or migration. The presence of the same MRSA clone in households suggested a close epidemic link. Reporting PVL-positive MRSA allows for early detection and targeted control measures.
Article
Agriculture, Dairy & Animal Science
Abraham Fikru Mechesso, Su-Jeong Kim, Ho-Sung Park, Ji-Hyun Choi, Hyun-Ju Song, Mi Hyun Kim, Suk-kyung Lim, Soon-Seek Yoon, Dong-Chan Moon
Summary: This study identified 199 Staphylococcus aureus isolates from quarter milk samples of 1,289 dairy cattle between 2014 and 2018, and found 30 MRSA strains. The research suggests that dairy cows could be a major source for spreading MRSA, indicating the need for enhanced hygienic measures.
JOURNAL OF DAIRY SCIENCE
(2021)
Review
Microbiology
Opeyemi Uwangbaoje Lawal, Olaniyi Ayobami, Alaa Abouelfetouh, Nadira Mourabit, Mamadou Kaba, Beverly Egyir, Shima M. Abdulgader, Adebayo Osagie Shittu
Summary: This study provides an update on the clonal distribution of MRSA in Africa, identifying diverse genotypes of MRSA across the continent with ST5 and ST8 clones being commonly found. There is a need to strengthen genomic surveillance capacity to prevent and control the spread of MRSA.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Multidisciplinary Sciences
Frederike Waldeck, Salome N. Seiffert, Susanne Manser, Danuta Zemp, Angela Walt, Christoph Berger, Werner C. Albrich, Matthias Schlegel, Tim Roloff, Adrian Egli, Oliver Nolte, Christian R. Kahlert
Summary: In our tertiary children's hospital, the number of newly detected methicillin-resistant Staphylococcus aureus (MRSA) infections among primary and secondary school students has almost doubled in recent years. Through an epidemiological investigation and characterization analysis, a cluster of pneumococci with common genetic features was identified, with a specific school being identified as a common risk factor for infection. No further cases were found after disinfection.
SCIENTIFIC REPORTS
(2022)
Article
Infectious Diseases
Yueh-Ling Chen, Eugene Yu-Chuan Kang, Lung-Kun Yeh, David H. K. Ma, Hsin-Yuan Tan, Hung-Chi Chen, Kuo-Hsuan Hung, Yhu-Chering Huang, Ching-Hsi Hsiao
Summary: This study analyzed the clinical and molecular characteristics of MSSA ocular infections in Taiwan and compared them between CA and HA infections. CA-MSSA strains had a significantly higher rate of keratitis but a lower rate of conjunctivitis compared to HA-MSSA strains. Both CA-MSSA and HA-MSSA isolates were highly susceptible to various antibiotics.
Article
Infectious Diseases
Souhir Kmiha, Ahlem Jouini, Nahawend Zerriaa, Safa Hamrouni, Lamia Thabet, Abderrazak Maaroufi
Summary: In this study, MRSA strains were isolated from burned patients in Tunisia and characterized for molecular typing, antibiotic resistance, and virulence factors. The results showed the emergence of multi-resistant strains with a wide variety of toxins and resistance genes. These findings highlight the potential risk of MRSA spread and complicating infection treatment in hospitals and the environment.
Article
Microbiology
Hiroshi Kaneko, Miki Kanai, Takumi Saito, Yuka Yanagi, Hana Kobayashi, Rikuto Kurihara, Masami Ikeda, Osamu Nemoto, Naoko Baba, Yasushi Matsuzaki, Daisuke Sawamura, Fumiko Shimoe, Yoichi Inaba, Yoko Kobayashi, Satoru Kawasaki, Toru Ueki, Sakae Funatsu, Shigeho Shirahama, Misao Oba, Takaya Hasegawa, Hirotoshi Furukawa, Toshiko Miyata, Masaaki Isonokami, Shigeru Fujita, Hidemasa Nakaminami
Summary: The study indicated a significant increase in PVL-positive MRSA isolates in the Japanese community, with the USA300 variant psi USA300 emerging as the predominant clone across regions in Japan. This variant may have a greater propensity to cause deep-seated SSTIs compared to USA300.
MICROBIOLOGY SPECTRUM
(2023)
Article
Infectious Diseases
Zahra Najafi olya, Shahin Najar-Peerayeh, Abbas Yadegar, Bita Bakhshi
Summary: A high prevalence of PVL-positive CA-MRSA strains was detected in Iran, with the majority of PVL-positive isolates being of H (mostly H2) variant, while 100% of PVL-positive MRSA strains harbored R variant. Additionally, CC8, CC22, and CC30 were identified as the dominant clones among PVL-encoding S. aureus strains.
BMC INFECTIOUS DISEASES
(2021)
Article
Agriculture, Dairy & Animal Science
Nadia Safia Chenouf, Olouwafemi Mistourah Mama, Chafik Redha Messai, Laura Ruiz-Ripa, Rosa Fernandez-Fernandez, Isabel Carvalho, Abdelghani Zitouni, Ahcene Hakem, Carmen Torres
Summary: This study investigated antimicrobial resistance and virulence factors in Staphylococcus aureus and coagulase-negative staphylococci in unpasteurized milk in Djelfa, Algeria. The results showed contamination of milk samples with these bacteria, with some strains exhibiting resistance to multiple drugs and carrying various resistance genes.
JOURNAL OF DAIRY SCIENCE
(2021)
Article
Public, Environmental & Occupational Health
J. Hatcher, S. Godambe, H. Lyall, L. Tyszczuk, F. Stubbs, N. Cummings, K. Sheils, C. Hughes, T. Kadhani, S. Atkin, N. Elaby, B. Pichon, B. Patel, E. T. Brannigan
Summary: The novel coronavirus (SARS-CoV-2) is a newly emerged coronavirus that was first discovered in Wuhan, China and has caused a global pandemic. It causes COVID-19, an infectious disease that can result in symptoms such as fever, cough, and difficulty breathing. The COVID-19 pandemic has had a significant impact on global healthcare systems and economies, leading many countries to implement strict isolation and control measures, including travel restrictions, lockdowns, and social distancing measures.
JOURNAL OF HOSPITAL INFECTION
(2022)
Article
Immunology
Nancy Evelyn Aguilar-Gomez, Jocelin Merida-Vieyra, Oscar Daniel Isunza-Alonso, Maria Gabriela Morales-Pirela, Oscar Colin-Martinez, Enrique Josue Juarez-Benitez, Silvestre Garcia de la Puente, Alejandra Aquino-Andrade
Summary: This study describes the phenotypic and genotypic characteristics of Staphylococcus aureus isolates from osteoarticular infections in paediatric patients. The majority of isolates were methicillin-sensitive S. aureus, and the pvl gene was only observed in these isolates. The study highlights the importance of a multidisciplinary team for the diagnosis and treatment of osteoarticular infections.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2022)
Article
Microbiology
Tobias Grebe, Viktoria Rudolf, Christiane Sidonie Gouleu, Bettina Loeffler, Ayola Akim Adegnika, Adebayo Osagie Shittu, Stefanie Deinhardt-Emmer, Silke Niemann, Frieder Schaumburg
Summary: The study found that Africans have higher levels of neutralizing anti-PVL antibodies, but it remains uncertain whether these antibodies provide protection against PVL-related diseases.
Article
Biology
Funda Yildirim, Mert Sudagidan, Ali Aydin, Ibrahim Akyazi, Gulay Merve Bayrakal, Orhan Yavuz, Aydin Gurel
Summary: This study demonstrates the pathogenicity of foodborne PVL-positive MSSA strains in vivo, showing that they can cause acute necrotising pneumonia and significantly elevate the expression of important inflammatory factors.
Article
Infectious Diseases
Stefan Monecke, Amira K. Bedewy, Elke Mueller, Sascha D. Braun, Celia Diezel, Amel Elsheredy, Ola Kader, Martin Reinicke, Abeer Ghazal, Shahinda Rezk, Ralf Ehricht
Summary: The study characterised MRSA isolates from a tertiary care centre in Alexandria, Egypt. The isolates belonged to 11 different clonal complexes and 14 strains, with CC15-MRSA-[V+fus] and CC1-MRSA-[V+fus+tir+ccrA/B-1] (PVL+) being the most common strains. Most isolates carried variant SCCmec elements and the fusidic acid resistance gene fusC. PVL genes were also prevalent. The study revealed an increase in fusC and PVL carriage and a decrease in the prevalence of the CC239 strain when compared to data from a previous study.
Article
Infectious Diseases
Stefan Monecke, Patrick Eberechi Akpaka, Margaret R. Smith, Chandrashekhar G. Unakal, Camille-Ann Thoms Rodriguez, Khalil Ashraph, Elke Mueller, Sascha D. Braun, Celia Diezel, Martin Reinicke, Ralf Ehricht
Summary: The aim of this study was to comprehensively characterise S. aureus strains from Trinidad and Tobago, and Jamaica. A total of 101 isolates were collected, mainly from patients with skin and soft tissue infections. The isolates were characterised using DNA microarray and the production of Panton-Valentine leukocidin (PVL) was examined. The study found high rates of PVL genes in methicillin-susceptible S. aureus (MSSA) isolates, with a local CC8-MSSA clone and CC152-MSSA being the main contributors. Ten MRSA isolates were identified, including the pandemic ST239-MRSA-III strain and five isolates with a composite SCCmec element not observed elsewhere.
Article
Immunology
Sarah A. Buchan, Hannah Chung, Timothy Karnauchow, J. Dayre McNally, Michael A. Campitelli, Jonathan B. Gubbay, Kevin Katz, Allison J. McGeer, David C. Richardson, Susan E. Richardson, Andrew Simor, Marek Smieja, George Zahariadis, Dat Than, Natasha S. Crowcroft, Laura C. Rosella, Jeffrey C. Kwong
PEDIATRIC INFECTIOUS DISEASE JOURNAL
(2019)
Article
Biotechnology & Applied Microbiology
Adriana Peci, Anne-Luise Winter, Ye Li, Saravanamuttu Gnaneshan, Juan Liu, Samira Mubareka, Jonathan B. Gubbay
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
(2019)
Article
Virology
Mohammed Ziaur Rahman, Mariya Sumiya, Mohammed Sahabuddin, Lisa G. Pell, Jonathan B. Gubbay, Rajibur Rahman, Farhana Momtaz, Nafisa Azmuda, Shaila S. Shanta, Ishrat Jahan, Mustafizur Rahman, Abdullah A. Mahmud, Daniel E. Roth, Shaun K. Morris
JOURNAL OF MEDICAL VIROLOGY
(2019)
Article
Infectious Diseases
Danuta M. Skowronski, Siobhan Leir, Suzana Sabaiduc, Michelle Murti, James A. Dickinson, Romy Olsha, Jonathan B. Gubbay, Matthew A. Croxen, Hugues Charest, Tracy Chan, Nathalie Bastien, Yan Li, Mel Krajden, Gaston De Serres
Article
Infectious Diseases
Lauren C. Ramsay, Natasha S. Crowcroft, Shari Thomas, Elena Aruffo, Alexandra Teslya, Jane M. Heffernan, Effie Gournis, Joanne Hiebert, Valerie Jaeger, Manisa Jiaravuthisan, Jennifer Sharron, Alberto Severini, Shelley L. Deeks, Jonathan Gubbay, Tony Mazzulli, Beate Sander
Article
Infectious Diseases
Danuta M. Skowronski, Siobhan Leir, Gaston De Serres, Michelle Murti, James A. Dickinson, Anne-Luise Winter, Romy Olsha, Matthew A. Croxen, Steven J. Drews, Hugues Charest, Christine Martineau, Suzana Sabaiduc, Nathalie Bastien, Yan Li, Martin Petric, Agatha Jassem, Mel Krajden, Jonathan B. Gubbay
Article
Environmental Sciences
Lily Yip, Mairead Finn, Andrea Granados, Karren Prost, Allison McGeer, Jonathan B. Gubbay, James Scott, Samira Mubareka
JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL HYGIENE
(2019)
Editorial Material
Hematology
Iain B. Gosbell, Veronica C. Hoad, Claire E. Styles, June Lee, Clive R. Seed
Article
Microbiology
Rachel R. Higgins, Adriana Peci, Mark Cardona, Jonathan B. Gubbay
Article
Hematology
Clive R. Seed, Claire E. Styles, Veronica C. Hoad, Hung Yang, Michael J. Thomas, Iain B. Gosbell
Summary: The majority of early HIV infections can be detected within four weeks after cessation of PrEP, with a three-month deferral period for blood donation in Australia providing an appropriate safety margin to mitigate the residual risk of transfusion-transmitted HIV.
Article
Virology
Adriana Peci, Vanessa Tran, Jennifer L. Guthrie, Ye Li, Paul Nelson, Kevin L. Schwartz, AliReza Eshaghi, Sarah A. Buchan, Jonathan B. Gubbay
Summary: This study evaluated the prevalence of co-infections of SARS-CoV-2 with seasonal respiratory viruses, finding a lower proportion of co-infections with generally mild symptoms. Testing for seasonal respiratory viruses should be performed in severely ill individuals to assist with patient management.
Article
Public, Environmental & Occupational Health
Jonathan B. Gubbay, Heather Rilkoff, Heather L. Kristjanson, Jessica D. Forbes, Michelle Murti, AliReza Eshaghi, George Broukhanski, Antoine Corbeil, Nahuel Fittipaldi, Jessica P. Hopkins, Erik Kristjanson, Julianne Kus, Liane Macdonald, Anna Majury, Gustavo Mallo, Tony Mazzulli, Roberto G. Melano, Romy Olsha, Stephen J. Perusini, Vanessa Tran, Vanessa G. Allen, Samir N. Patel
Summary: Retesting positive specimens from different pre-test probability groups with an alternate assay showed significantly lower reproducibility in the lowest pre-test probability group, highlighting the need for thorough evaluation of large-scale SARS-CoV-2 screening testing initiatives among low pre-test probability populations to prevent potential harm from false-positive results.
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
(2021)
Review
Hematology
Philip Kiely, Veronica C. Hoad, Clive R. Seed, Iain B. Gosbell
Summary: SARS-CoV-2 has a low risk of transmission through blood transfusion, as the presence of the virus in the blood is brief and at a low level. The main concern for blood services is to ensure the sufficiency of the blood supply while minimizing respiratory transmission.
TRANSFUSION MEDICINE AND HEMOTHERAPY
(2022)
Editorial Material
Medicine, General & Internal
Christopher D. Swan, Clive R. Seed, Claire E. Styles, Iain B. Gosbell
MEDICAL JOURNAL OF AUSTRALIA
(2023)
Editorial Material
Medicine, General & Internal
Philip Kiely, Veronica C. Hoad, Claire E. Styles, Iain B. Gosbell
MEDICAL JOURNAL OF AUSTRALIA
(2023)