Neutrophil extracellular traps and the dysfunctional innate immune response of cystic fibrosis lung disease: a review

Selective Biological Responses of Phagocytes and Lungs to Purified Histones

(2017) Fatemeh Fattahi et al.   Journal of Innate Immunity

Neutrophil extracellular trap formation in theStreptococcus suis-infected cerebrospinal fluid compartment

(2016) Nicole de Buhr et al.   CELLULAR MICROBIOLOGY

Pneumolysin activates neutrophil extracellular trap formation

(2016) J. G. Nel et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Modulating Innate and Adaptive Immunity by (R)-Roscovitine: Potential Therapeutic Opportunity in Cystic Fibrosis

(2016) Laurent Meijer et al.   Journal of Innate Immunity

Neutrophil extracellular trap formation is increased in psoriasis and induces human β-defensin-2 production in epidermal keratinocytes

(2016) Stephen Chu-Sung Hu et al.   Scientific Reports

Neutrophil extracellular traps are indirectly triggered by lipopolysaccharide and contribute to acute lung injury

(2016) Shuai Liu et al.   Scientific Reports

Free DNA in Cystic Fibrosis Airway Fluids Correlates with Airflow Obstruction

(2015) Veronica Marcos et al.   MEDIATORS OF INFLAMMATION

Neutrophil extracellular traps license macrophages for cytokine production in atherosclerosis

(2015) A. Warnatsch et al.   SCIENCE

Dogs cast NETs too: Canine neutrophil extracellular traps in health and immune-mediated hemolytic anemia

(2015) Unity Jeffery et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

Molecular mechanisms of NET formation and degradation revealed by intravital imaging in the liver vasculature

(2015) Elzbieta Kolaczkowska et al.   Nature Communications

A neutrophil intrinsic impairment affecting Rab27a and degranulation in cystic fibrosis is corrected by CFTR potentiator therapy

(2014) K. Pohl et al.   BLOOD

NET formation induced by Pseudomonas aeruginosa cystic fibrosis isolates measured as release of myeloperoxidase–DNA and neutrophil elastase–DNA complexes

(2014) Dae-goon Yoo et al.   IMMUNOLOGY LETTERS

Cystic Fibrosis Sputum DNA Has NETosis Characteristics and Neutrophil Extracellular Trap Release Is Regulated by Macrophage Migration-Inhibitory Factor

(2014) Markryan Dwyer et al.   Journal of Innate Immunity

Neutrophils sense microbe size and selectively release neutrophil extracellular traps in response to large pathogens

(2014) Nora Branzk et al.   NATURE IMMUNOLOGY

NETosis: how vital is it?

(2013) B. G. Yipp et al.   BLOOD

Extracellular histones are essential effectors of C5aR- and C5L2-mediated tissue damage and inflammation in acute lung injury

(2013) Markus Bosmann et al.   FASEB JOURNAL

Risk Factors for Bronchiectasis in Children with Cystic Fibrosis

(2013) Peter D. Sly et al.   NEW ENGLAND JOURNAL OF MEDICINE

Sputum Biomarkers of Inflammation and Lung Function Decline in Children with Cystic Fibrosis

(2012) Scott D. Sagel et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Circulating Histones Are Mediators of Trauma-associated Lung Injury

(2012) Simon T. Abrams et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Influence of DNA on the Activities and Inhibition of Neutrophil Serine Proteases in Cystic Fibrosis Sputum

(2012) Alice V. Dubois et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Neutrophil Extracellular Trap (NET) Impact on Deep Vein Thrombosis

(2012) Tobias A. Fuchs et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Neutrophil Extracellular Traps: Double-Edged Swords of Innate Immunity

(2012) M. J. Kaplan et al.   JOURNAL OF IMMUNOLOGY

Absence of the cystic fibrosis transmembrane regulator (Cftr ) from myeloid-derived cells slows resolution of inflammation and infection

(2012) T. L. Bonfield et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Influences of Chloride and Hypochlorite on Neutrophil Extracellular Trap Formation

(2012) Kathryn Akong-Moore et al.   PLoS One

Role of CFTR expressed by neutrophils in modulating acute lung inflammation and injury in mice

(2011) Xiao Su et al.   INFLAMMATION RESEARCH

Effect of dornase alfa on inflammation and lung function: Potential role in the early treatment of cystic fibrosis

(2011) Michael W. Konstan et al.   Journal of Cystic Fibrosis

Abnormal Trafficking and Degradation of TLR4 Underlie the Elevated Inflammatory Response in Cystic Fibrosis

(2011) E. M. Bruscia et al.   JOURNAL OF IMMUNOLOGY

Neutrophil Extracellular Trap (NET)-Mediated Killing of Pseudomonas aeruginosa: Evidence of Acquired Resistance within the CF Airway, Independent of CFTR

(2011) Robert L. Young et al.   PLoS One

Sputum and serum calprotectin are useful biomarkers during CF exacerbation

(2010) R.D. Gray et al.   Journal of Cystic Fibrosis

In Cystic Fibrosis Homozygotes and Heterozygotes, Neutrophil Apoptosis Is Delayed and Modulated by Diamide or Roscovitine: Evidence for an Innate Neutrophil Disturbance

(2010) Sandra Moriceau et al.   Journal of Innate Immunity

Proinflammatory Phenotype and Increased Caveolin-1 in Alveolar Macrophages with Silenced CFTR mRNA

(2010) Yaqin Xu et al.   PLoS One

Impairment of neutrophil extracellular trap degradation is associated with lupus nephritis

(2010) A. Hakkim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Azithromycin Reduces Exaggerated Cytokine Production by M1 Alveolar Macrophages in Cystic Fibrosis

(2009) Magali Meyer et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Histone hypercitrullination mediates chromatin decondensation and neutrophil extracellular trap formation

(2009) Yanming Wang et al.   JOURNAL OF CELL BIOLOGY

Azithromycin and Clarithromycin Inhibit Lipopolysaccharide-Induced Murine Pulmonary Neutrophilia Mainly through Effects on Macrophage-Derived Granulocyte-Macrophage Colony-Stimulating Factor and Interleukin-1 

(2009) M. Bosnar et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Relationship between antimicrobial proteins and airway inflammation and infection in cystic fibrosis

(2009) Scott D. Sagel et al.   PEDIATRIC PULMONOLOGY

Neutrophil Extracellular Traps Contain Calprotectin, a Cytosolic Protein Complex Involved in Host Defense against Candida albicans

(2009) Constantin F. Urban et al.   PLoS Pathogens

Prolonged survival of neutrophils from patients with  F508 CFTR mutations

(2008) D J McKeon et al.   THORAX

Neutrophils in cystic fibrosis

(2008) D G Downey et al.   THORAX

Chicken heterophil extracellular traps (HETs): Novel defense mechanism of chicken heterophils

(2008) Phongsakorn Chuammitri et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY