Effect of the Large and Small T-Antigens of Human Polyomaviruses on Signaling Pathways

Dual inhibition of MDM2 and MDM4 in virus-positive Merkel cell carcinoma enhances the p53 response

(2019) Donglim Esther Park et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human polyomavirus BKV infection of endothelial cells results in interferon pathway induction and persistence

(2019) Ping An et al.   PLoS Pathogens

Merkel cell polyomavirus Tumor antigens expressed in Merkel cell carcinoma function independently of the ubiquitin ligases Fbw7 and β-TrCP

(2019) Kristine N. Dye et al.   PLoS Pathogens

The multiple mechanisms that regulate p53 activity and cell fate

(2019) Antonina Hafner et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Survivin at a glance

(2019) Sally P. Wheatley et al.   JOURNAL OF CELL SCIENCE

Temporal proteomic analysis of BK polyomavirus infection reveals virus-induced G2 arrest and highly effective evasion of innate immune sensing

(2019) Laura G. Caller et al.   JOURNAL OF VIROLOGY

BK polyomavirus activates the DNA damage response to prolong S phase

(2019) Joshua L. Justice et al.   JOURNAL OF VIROLOGY

Virus Control of Cell Metabolism for Replication and Evasion of Host Immune Responses

(2019) María Maximina B. Moreno-Altamirano et al.   Frontiers in Cellular and Infection Microbiology

High-Throughput Characterization of Viral and Cellular Protein Expression Patterns During JC Polyomavirus Infection

(2019) Jeanne K. DuShane et al.   Frontiers in Microbiology

Protein kinase C: perfectly balanced

(2018) Alexandra C. Newton   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

ERK Is a Critical Regulator of JC Polyomavirus Infection

(2018) Jeanne K. DuShane et al.   JOURNAL OF VIROLOGY

Signaling Pathways Involved in the Regulation of mRNA Translation

(2018) Philippe P. Roux et al.   MOLECULAR AND CELLULAR BIOLOGY

Microtubule dynamics: an interplay of biochemistry and mechanics

(2018) Gary J. Brouhard et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Deregulation of the Notch pathway as a common road in viral carcinogenesis

(2018) Elenaé Vázquez-Ulloa et al.   REVIEWS IN MEDICAL VIROLOGY

Role of BK human polyomavirus in cancer

(2018) Jorge Levican et al.   Infectious Agents and Cancer

Seroprevalence of fourteen human polyomaviruses determined in blood donors

(2018) Sergio Kamminga et al.   PLoS One

CCL17/TARC and CCR4 expression in Merkel Cell Carcinoma

(2018) Kashif Rasheed et al.   Oncotarget

Defining the frequency of human papillomavirus and polyomavirus infection in urothelial bladder tumours

(2018) Matthew A. Llewellyn et al.   Scientific Reports

Cellular sheddases are induced by Merkel cell polyomavirus small tumour antigen to mediate cell dissociation and invasiveness

(2018) Nnenna Nwogu et al.   PLoS Pathogens

The Smc5/6 Complex: New and Old Functions of the Enigmatic Long-Distance Relative

(2018) Luis Aragón   Annual Review of Genetics

Expression of Notch 3 and Jagged 1 Is Associated With Merkel Cell Polyomavirus Status and Prognosis in Merkel Cell Carcinoma

(2018) LUSI OKA WARDHANI et al.   ANTICANCER RESEARCH

Human polyomaviruses and cancer: an overview

(2018) JC Prado et al.   Clinics

Pharmacological inhibition of serine palmitoyl transferase and sphingosine kinase-1/-2 inhibits Merkel Cell Carcinoma cell proliferation

(2018) Vishwanath Kumble Bhat et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Human Oncoviruses: Mucocutaneous Manifestations, Pathogenesis, Therapeutics, and Prevention (Part I: Papillomaviruses and Merkel cell polyomavirus)

(2018) Christopher T. Haley et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

BRD4 and Cancer: going beyond transcriptional regulation

(2018) Benedetta Donati et al.   Molecular Cancer

Breaking Bad: How Viruses Subvert the Cell Cycle

(2018) Ying Fan et al.   Frontiers in Cellular and Infection Microbiology

Protein kinase C and cardiac dysfunction: a review

(2017) Raphael M. Singh et al.   HEART FAILURE REVIEWS

Association of expression of the hedgehog signal with Merkel cell polyomavirus infection and prognosis of Merkel cell carcinoma

(2017) Teruyuki Kuromi et al.   HUMAN PATHOLOGY

Biology, evolution, and medical importance of polyomaviruses: An update

(2017) Ugo Moens et al.   INFECTION GENETICS AND EVOLUTION

Multiple functions of the E3 ubiquitin ligase CHIP in immunity

(2017) Shaohua Zhan et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Interferons and beyond: Induction of antiretroviral restriction factors

(2017) Dominik Hotter et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Human polyomavirus 6 and 7 are associated with pruritic and dyskeratotic dermatoses

(2017) Khang D. Nguyen et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Dysregulation of the MEK/ERK/MNK1 signalling cascade by middle T antigen of the trichoydsplasia spinulosa polyomavirus

(2017) J.H. Wu et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Merkel Cell Polyomavirus Small T Antigen Drives Cell Motility via Rho-GTPase-Induced Filopodium Formation

(2017) Gabrielė Stakaitytė et al.   JOURNAL OF VIROLOGY

ATM, ATR, and DNA-PK: The Trinity at the Heart of the DNA Damage Response

(2017) Andrew N. Blackford et al.   MOLECULAR CELL

Nuclear receptors in cancer — uncovering new and evolving roles through genomic analysis

(2017) Vineet K. Dhiman et al.   NATURE REVIEWS GENETICS

Sphingolipids and their metabolism in physiology and disease

(2017) Yusuf A. Hannun et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Merkel cell polyomavirus small T antigen induces genome instability by E3 ubiquitin ligase targeting

(2017) H J Kwun et al.   ONCOGENE

Census and evaluation of p53 target genes

(2017) M Fischer   ONCOGENE

Protein-mediated viral latency is a novel mechanism for Merkel cell polyomavirus persistence

(2017) Hyun Jin Kwun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genomics and evolution of protein phosphatases

(2017) Mark J. Chen et al.   Science Signaling

Isolation and characterization of a novel putative human polyomavirus

(2017) Tarik Gheit et al.   VIROLOGY

The DNA damage response promotes polyomavirus JC infection by nucleus to cytoplasm NF- kappaB activation

(2017) Martyn K. White et al.   Virology Journal

The PP4R1 sub-unit of protein phosphatase PP4 is essential for inhibition of NF-κB by merkel polyomavirus small tumour antigen

(2017) Hussein Abdul-Sada et al.   Oncotarget

Merkel cell polyomavirus recruits MYCL to the EP400 complex to promote oncogenesis

(2017) Jingwei Cheng et al.   PLoS Pathogens

Review on the role of the human Polyomavirus JC in the development of tumors

(2017) Serena Delbue et al.   Infectious Agents and Cancer

Activation of Protein Kinase C ε in Merkel Cell Polyomavirus–Induced Merkel Cell Carcinoma

(2017) Adilson Costa et al.   JAMA Dermatology

Genomics and evolution of protein phosphatases

(2017) Mark J. Chen et al.   Science Signaling

The p53 Pathway: Origins, Inactivation in Cancer, and Emerging Therapeutic Approaches

(2016) Andreas C. Joerger et al.   Annual Review of Biochemistry

4E-BP1, a multifactor regulated multifunctional protein

(2016) Xiaoyu Qin et al.   CELL CYCLE

The Bromodomain and Extra-Terminal Domain (BET) Family: Functional Anatomy of BET Paralogous Proteins

(2016) Yasushi Taniguchi   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

ATM and ATR signaling at a glance

(2016) Poorwa Awasthi et al.   JOURNAL OF CELL SCIENCE

Emerging differential roles of the pRb tumor suppressor in trichodysplasia spinulosa-associated polyomavirus and Merkel cell polyomavirus pathogeneses

(2016) Julie H. Wu et al.   JOURNAL OF CLINICAL VIROLOGY

Molecular mechanisms supporting a pathogenic role for human polyomavirus 6 small T antigen: Protein phosphatase 2A targeting and MAPK cascade activation

(2016) Julie H. Wu et al.   JOURNAL OF MEDICAL VIROLOGY

The Brd4 acetyllysine-binding protein is involved in activation of polyomavirus JC

(2016) Hassen S. Wollebo et al.   JOURNAL OF NEUROVIROLOGY

Structure of the E6/E6AP/p53 complex required for HPV-mediated degradation of p53

(2016) Denise Martinez-Zapien et al.   NATURE

Eukaryotic initiation factor 4E-binding protein 1 (4E-BP1): a master regulator of mRNA translation involved in tumorigenesis

(2016) J Musa et al.   ONCOGENE

Wnt signaling in cancer

(2016) T Zhan et al.   ONCOGENE

Mitotic protein kinase CDK1 phosphorylation of mRNA translation regulator 4E-BP1 Ser83 may contribute to cell transformation

(2016) Celestino Velásquez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

JC Polyomavirus Infection of Primary Human Renal Epithelial Cells Is Controlled by a Type I IFN-Induced Response

(2016) Benedetta Assetta et al.   mBio

RB1 is the crucial target of the Merkel cell polyomavirus Large T antigen in Merkel cell carcinoma cells

(2016) Sonja Hesbacher et al.   Oncotarget

Interplay between the virus and the ubiquitin–proteasome system: molecular mechanism of viral pathogenesis

(2016) Honglin Luo   Current Opinion in Virology

Merkel Cell Polyomavirus Small T Antigen Promotes Pro-Glycolytic Metabolic Perturbations Required for Transformation

(2016) Christian Berrios et al.   PLoS Pathogens

The Ancient Evolutionary History of Polyomaviruses

(2016) Christopher B. Buck et al.   PLoS Pathogens

Viruses and the Diversity of Cell Death

(2016) Pranav Danthi   Annual Review of Virology

The Regulation of NF-κB Subunits by Phosphorylation

(2016) Frank Christian et al.   Cells

Molecular insight into the viral biology and clinical features of trichodysplasia spinulosa

(2015) J.H. Wu et al.   BRITISH JOURNAL OF DERMATOLOGY

Comparison of Akt/mTOR/4E-BP1 pathway signal activation and mutations of PIK3CA in Merkel cell polyomavirus–positive and Merkel cell polyomavirus–negative carcinomas

(2015) Takeshi Iwasaki et al.   HUMAN PATHOLOGY

Cutaneous Human Polyomavirus Small T Antigens and 4E-BP1 Targeting

(2015) Julie H. Wu et al.   INTERVIROLOGY

Correlation of Merkel cell polyomavirus positivity with PDGFRα mutations and survivin expression in Merkel cell carcinoma

(2015) M. Batinica et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Merkel cell polyomavirus T antigens promote cell proliferation and inflammatory cytokine gene expression

(2015) Kathleen F. Richards et al.   JOURNAL OF GENERAL VIROLOGY

Merkel Cell Polyomavirus Small T Antigen Is Oncogenic in Transgenic Mice

(2015) Monique E. Verhaegen et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Quantitative Proteomic Analysis of Enriched Nuclear Fractions from BK Polyomavirus-Infected Primary Renal Proximal Tubule Epithelial Cells

(2015) Joshua L. Justice et al.   JOURNAL OF PROTEOME RESEARCH

New insights on the association between the prostate cancer and the small DNA tumour virus, BK polyomavirus

(2015) Mauro Tognon et al.   Journal of Translational Medicine

Restricted Protein Phosphatase 2A Targeting by Merkel Cell Polyomavirus Small T Antigen

(2015) Hyun Jin Kwun et al.   JOURNAL OF VIROLOGY

Viral DNA Replication-Dependent DNA Damage Response Activation during BK Polyomavirus Infection

(2015) Brandy Verhalen et al.   JOURNAL OF VIROLOGY

BK virus infection activates the TNFα/TNF receptor system in Polyomavirus-associated nephropathy

(2015) Andrea Ribeiro et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

The PI3K/AKT/mTOR interactive pathway

(2015) Tulin Ersahin et al.   Molecular BioSystems

Human JC virus small tumour antigen inhibits nucleotide excision repair and sensitises cells to DNA-damaging agents

(2015) Jau-Ling Huang et al.   MUTAGENESIS

CDK1 substitutes for mTOR kinase to activate mitotic cap-dependent protein translation

(2015) Masahiro Shuda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Response of host inflammasomes to viral infection

(2015) I-Yin Chen et al.   TRENDS IN MICROBIOLOGY

Polyomavirus T antigens activate an antiviral state

(2015) Nicholas S. Giacobbi et al.   VIROLOGY

Viral activation of cellular metabolism

(2015) Erica L. Sanchez et al.   VIROLOGY

Inflammasome control of viral infection

(2015) Christopher Lupfer et al.   Current Opinion in Virology

Regulation of p53: a collaboration between Mdm2 and Mdmx

(2015) Dongsheng Pei et al.   Oncotarget

Prokineticins and Merkel cell polyomavirus infection in Merkel cell carcinoma

(2014) S Lauttia et al.   BRITISH JOURNAL OF CANCER

Human Viral Oncogenesis: A Cancer Hallmarks Analysis

(2014) Enrique A. Mesri et al.   Cell Host & Microbe

Phosphorylation of Merkel Cell Polyomavirus Large Tumor Antigen at Serine 816 by ATM Kinase Induces Apoptosis in Host Cells

(2014) Jing Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of a Novel Polyomavirus in a Pancreatic Transplant Recipient With Retinal Blindness and Vasculitic Myopathy

(2014) Nischay Mishra et al.   JOURNAL OF INFECTIOUS DISEASES

Human Polyomavirus 7-Associated Pruritic Rash and Viremia in Transplant Recipients

(2014) J. Ho et al.   JOURNAL OF INFECTIOUS DISEASES

Merkel Cell Polyomavirus Small T Antigen Mediates Microtubule Destabilization To Promote Cell Motility and Migration

(2014) Laura M. Knight et al.   JOURNAL OF VIROLOGY

Host DNA Damage Response Factors Localize to Merkel Cell Polyomavirus DNA Replication Sites To Support Efficient Viral DNA Replication

(2014) S. H. Tsang et al.   JOURNAL OF VIROLOGY

Activation of c-Myc and Cyclin D1 by JCV T-Antigen and β-Catenin in Colon Cancer

(2014) Michael J. Ripple et al.   PLoS One

Polyomavirus-Associated Trichodysplasia Spinulosa Involves Hyperproliferation, pRB Phosphorylation and Upregulation of p16 and p21

(2014) Siamaque Kazem et al.   PLoS One

Binding of the Trichodysplasia Spinulosa–Associated Polyomavirus Small T Antigen to Protein Phosphatase 2A: Elucidation of a Potential Pathogenic Mechanism in a Rare Skin Disease

(2014) Harrison P. Nguyen et al.   JAMA Dermatology

The Multifunctional Protein Kinase C-ε in Cancer Development and Progression

(2014) Kirti Jain et al.   Cancers

Pattern recognition receptors in innate immunity, host defense, and immunopathology

(2013) Rahul Suresh et al.   ADVANCES IN PHYSIOLOGY EDUCATION

Thetrichodysplasia spinulosa-associated polyomavirus: virological background and clinical implications

(2013) Siamaque Kazem et al.   APMIS

Regulation of proteasome activity in health and disease

(2013) Marion Schmidt et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Merkel Cell Polyomavirus Small T Antigen Controls Viral Replication and Oncoprotein Expression by Targeting the Cellular Ubiquitin Ligase SCFFbw7

(2013) Hyun Jin Kwun et al.   Cell Host & Microbe

The presence of Merkel cell polyomavirus is associated with deregulated expression ofBRAFandBcl-2genes in non-small cell lung cancer

(2013) I. Lasithiotaki et al.   INTERNATIONAL JOURNAL OF CANCER

Merkel Cell Polyomavirus Large T Antigen Disrupts Host Genomic Integrity and Inhibits Cellular Proliferation

(2013) J. Li et al.   JOURNAL OF VIROLOGY

Merkel Cell Polyomavirus Large T Antigen Has Growth-Promoting and Inhibitory Activities

(2013) J. Cheng et al.   JOURNAL OF VIROLOGY

High-Affinity Rb Binding, p53 Inhibition, Subcellular Localization, and Transformation by Wild-Type or Tumor-Derived Shortened Merkel Cell Polyomavirus Large T Antigens

(2013) S. Borchert et al.   JOURNAL OF VIROLOGY

Merkel Cell Polyomavirus Small T Antigen Targets the NEMO Adaptor Protein To Disrupt Inflammatory Signaling

(2013) D. A. Griffiths et al.   JOURNAL OF VIROLOGY

The T Antigen Locus of Merkel Cell Polyomavirus Downregulates Human Toll-Like Receptor 9 Expression

(2013) Naveed Shahzad et al.   JOURNAL OF VIROLOGY

A cornucopia of human polyomaviruses

(2013) James A. DeCaprio et al.   NATURE REVIEWS MICROBIOLOGY

Molecular mechanisms underlying RB protein function

(2013) Frederick A. Dick et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Protein kinase C and cancer: what we know and what we do not

(2013) R Garg et al.   ONCOGENE

Identification of a Novel Human Polyomavirus in Organs of the Gastrointestinal Tract

(2013) Sarah Korup et al.   PLoS One

Human polyomaviruses in disease and cancer

(2013) Tina Dalianis et al.   VIROLOGY

Signaling by Nuclear Receptors

(2013) R. Sever et al.   Cold Spring Harbor Perspectives in Biology

DNA Damage Sensing by the ATM and ATR Kinases

(2013) A. Marechal et al.   Cold Spring Harbor Perspectives in Biology

The Merkel Cell Polyomavirus Minor Capsid Protein

(2013) Rachel M. Schowalter et al.   PLoS Pathogens

Epigenetic and genetic features of 24 colon cancer cell lines

(2013) D Ahmed et al.   Oncogenesis

Molecular Pathways: The Hedgehog Signaling Pathway in Cancer

(2012) R. McMillan et al.   CLINICAL CANCER RESEARCH

Activation of PI3K Signaling in Merkel Cell Carcinoma

(2012) Valentina Nardi et al.   CLINICAL CANCER RESEARCH

PP1 and PP2A phosphatases - cooperating partners in modulating retinoblastoma protein activation

(2012) Victoria Kolupaeva et al.   FEBS Journal

The Fbw7 and BetaTRCP E3 ubiquitin ligases and their roles in tumorigenesis

(2012) Alan et al.   Frontiers in Bioscience-Landmark

PP2A holoenzymes negatively and positively regulate cell cycle progression by dephosphorylating pocket proteins and multiple CDK substrates

(2012) Alison Kurimchak et al.   GENE

DNA damage-dependent NF-κB activation: NEMO turns nuclear signaling inside out

(2012) Kevin W. McCool et al.   IMMUNOLOGICAL REVIEWS

Survivin downregulation is not required for T antigen knockdown mediated cell growth inhibition in MCV infected merkel cell carcinoma cells

(2012) David Schrama et al.   INTERNATIONAL JOURNAL OF CANCER

Polyomavirus JC infection inhibits differentiation of oligodendrocyte progenitor cells

(2012) Armine Darbinyan et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Identification of MW Polyomavirus, a Novel Polyomavirus in Human Stool

(2012) E. A. Siebrasse et al.   JOURNAL OF VIROLOGY

Carcinogenicity of malaria and of some polyomaviruses

(2012) Véronique Bouvard et al.   LANCET ONCOLOGY

Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins

(2012) Orit Rozenblatt-Rosen et al.   NATURE

Activation of the PI3K/AKT Pathway in Merkel Cell Carcinoma

(2012) Christian Hafner et al.   PLoS One

JC Virus T-Antigen Regulates Glucose Metabolic Pathways in Brain Tumor Cells

(2012) Evan Noch et al.   PLoS One

Bag3-Induced Autophagy Is Associated with Degradation of JCV Oncoprotein, T-Ag

(2012) Ilker Kudret Sariyer et al.   PLoS One

Discovery of a Novel Polyomavirus in Acute Diarrheal Samples from Children

(2012) Guixia Yu et al.   PLoS One

Disruption of PH-kinase domain interactions leads to oncogenic activation of AKT in human cancers

(2012) C. Parikh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Survivin Is a Therapeutic Target in Merkel Cell Carcinoma

(2012) R. Arora et al.   Science Translational Medicine

Bcl-2 expression indicates better prognosis of Merkel cell carcinoma regardless of the presence of Merkel cell polyomavirus

(2012) Helka Sahi et al.   VIRCHOWS ARCHIV

Agnoprotein of mammalian polyomaviruses

(2012) Nancy Gerits et al.   VIROLOGY

Cooperative roles of NF-κB and NFAT4 in polyomavirus JC regulation at the KB control element

(2012) Hassen S. Wollebo et al.   VIROLOGY

The VP1 subunit of JC polyomavirus recapitulates early events in viral trafficking and is a novel tool to study polyomavirus entry

(2012) Christian D.S. Nelson et al.   VIROLOGY

Discovery of STL polyomavirus, a polyomavirus of ancestral recombinant origin that encodes a unique T antigen by alternative splicing

(2012) Efrem S. Lim et al.   VIROLOGY

MCV and Merkel cell carcinoma: a molecular success story

(2012) Reety Arora et al.   Current Opinion in Virology

Roles of ATM and ATR-Mediated DNA Damage Responses during Lytic BK Polyomavirus Infection

(2012) Mengxi Jiang et al.   PLoS Pathogens

Bromodomain Protein Brd4 Plays a Key Role in Merkel Cell Polyomavirus DNA Replication

(2012) Xin Wang et al.   PLoS Pathogens

Aberrant Activation of the Hedgehog Signaling Pathway in Malignant Hematological Neoplasms

(2011) Chi Young Ok et al.   AMERICAN JOURNAL OF PATHOLOGY

Nuclear Receptors as Modulators of the Tumor Microenvironment

(2011) M. H. Sherman et al.   Cancer Prevention Research

p53 Negatively Regulates the Hepatoma Growth Factor HDGF

(2011) Y. Sasaki et al.   CANCER RESEARCH

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Role of Rho GTPases and their regulators in cancer progression

(2011) Rajamani Rathinam   Frontiers in Bioscience-Landmark

Merkel Cell Polyomavirus Large T Antigen Disrupts Lysosome Clustering by Translocating Human Vam6p from the Cytoplasm to the Nucleus

(2011) Xi Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nuclear IRS-1 and cancer

(2011) Krzysztof Reiss et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Human Merkel cell polyomavirus small T antigen is an oncoprotein targeting the 4E-BP1 translation regulator

(2011) Masahiro Shuda et al.   JOURNAL OF CLINICAL INVESTIGATION

A Novel Human Polyomavirus Closely Related to the African Green Monkey-Derived Lymphotropic Polyomavirus

(2011) N. Scuda et al.   JOURNAL OF VIROLOGY

Activation of innate immune defense mechanisms contributes to polyomavirus BK-associated nephropathy

(2011) Andrea Ribeiro et al.   KIDNEY INTERNATIONAL

Activation and Function of the MAPKs and Their Substrates, the MAPK-Activated Protein Kinases

(2011) M. Cargnello et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Viruses as key regulators of angiogenesis

(2011) Kristof Vrancken et al.   REVIEWS IN MEDICAL VIROLOGY

Detection of viral DNA sequences in sporadic colorectal cancers in relation to CpG island methylation and methylator phenotype

(2011) Pawel Karpinski et al.   TUMOR BIOLOGY

Dynamics of the Rho-family small GTPases in actin regulation and motility

(2011) Désirée Spiering et al.   Cell Adhesion & Migration

Prokineticins in angiogenesis and cancer

(2010) Justin Monnier et al.   CANCER LETTERS

Merkel Cell Polyomavirus and Two Previously Unknown Polyomaviruses Are Chronically Shed from Human Skin

(2010) Rachel M. Schowalter et al.   Cell Host & Microbe

B55α PP2A Holoenzymes Modulate the Phosphorylation Status of the Retinoblastoma-related Protein p107 and Its Activation

(2010) Girish Jayadeva et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MAP kinase activation increases BK polyomavirus replication and facilitates viral propagation in vitro

(2010) Mark E. Seamone et al.   JOURNAL OF VIROLOGICAL METHODS

The presence of JC virus in gastric carcinomas correlates with patient's age, intestinal histological type and aberrant methylation of tumor suppressor genes

(2010) Feryel Ksiaa et al.   MODERN PATHOLOGY

JC Virus Small t Antigen Binds Phosphatase PP2A and Rb Family Proteins and Is Required for Efficient Viral DNA Replication Activity

(2010) Brigitte Bollag et al.   PLoS One

Regulation of sphingosine kinase and sphingolipid signaling

(2010) Stuart M. Pitson   TRENDS IN BIOCHEMICAL SCIENCES

Interaction and co-localization of JC virus large T antigen and the F-box protein β-transducin-repeat containing protein

(2010) Marta M. Reviriego-Mendoza et al.   VIROLOGY

Discovery of a New Human Polyomavirus Associated with Trichodysplasia Spinulosa in an Immunocompromized Patient

(2010) Els van der Meijden et al.   PLoS Pathogens

The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism

(2009) Raphael Kopan et al.   CELL

Pathogen Recognition and Inflammatory Signaling in Innate Immune Defenses

(2009) T. H. Mogensen   CLINICAL MICROBIOLOGY REVIEWS

Insulin Receptor Isoforms and Insulin Receptor/Insulin-Like Growth Factor Receptor Hybrids in Physiology and Disease

(2009) Antonino Belfiore et al.   ENDOCRINE REVIEWS

Expression of hedgehog signaling molecules in Merkel cell carcinoma

(2009) Markus Brunner et al.   HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK

Large T Antigen Promotes JC Virus Replication in G2-arrested Cells by Inducing ATM- and ATR-mediated G2Checkpoint Signaling

(2009) Yasuko Orba et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of Microtubule Dynamic Instabilityin Vitroby Differentially Phosphorylated Stathmin

(2009) Tapas Manna et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evidence for modulation of BAG3 by polyomavirus JC early protein

(2009) A. Basile et al.   JOURNAL OF GENERAL VIROLOGY

Simian Virus 40 Small T Antigen Activates AMPK and Triggers Autophagy To Protect Cancer Cells from Nutrient Deprivation

(2009) S. H. Kumar et al.   JOURNAL OF VIROLOGY

JC Virus Mediates Invasion and Migration in Colorectal Metastasis

(2009) Alexander Link et al.   PLoS One

Global effects of BKV infection on gene expression in human primary kidney epithelial cells

(2009) Johanna R. Abend et al.   VIROLOGY

TP53 Mutations in Human Cancers: Origins, Consequences, and Clinical Use

(2009) M. Olivier et al.   Cold Spring Harbor Perspectives in Biology

Seroepidemiology of Human Polyomaviruses

(2009) Jaime M. Kean et al.   PLoS Pathogens

The BAG proteins: a ubiquitous family of chaperone regulators

(2008) M. Kabbage et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Simian Virus 40 Large T Antigen Disrupts Genome Integrity and Activates a DNA Damage Response via Bub1 Binding

(2008) J. Hein et al.   JOURNAL OF VIROLOGY

Interaction between Simian Virus 40 Large T Antigen and Insulin Receptor Substrate 1 Is Disrupted by the K1 Mutation, Resulting in the Loss of Large T Antigen-Mediated Phosphorylation of Akt

(2008) Y. Yu et al.   JOURNAL OF VIROLOGY

The TORrid affairs of viruses: effects of mammalian DNA viruses on the PI3K–Akt–mTOR signalling pathway

(2008) Nicholas J. Buchkovich et al.   NATURE REVIEWS MICROBIOLOGY

T antigen mutations are a human tumor-specific signature for Merkel cell polyomavirus

(2008) M. Shuda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Clonal Integration of a Polyomavirus in Human Merkel Cell Carcinoma

(2008) H. Feng et al.   SCIENCE

PP2A holoenzyme assembly: in cauda venenum (the sting is in the tail)

(2008) Veerle Janssens et al.   TRENDS IN BIOCHEMICAL SCIENCES

Dephosphorylation of JC virus agnoprotein by protein phosphatase 2A: Inhibition by small t antigen

(2008) Ilker K. Sariyer et al.   VIROLOGY