Organoids-on-a-chip

Flow-enhanced vascularization and maturation of kidney organoids in vitro

(2019) Kimberly A. Homan et al.   NATURE METHODS

Vascularized Liver Organoids Generated Using Induced Hepatic Tissue and Dynamic Liver-Specific Microenvironment as a Drug Testing Platform

(2018) Yoonhee Jin et al.   ADVANCED FUNCTIONAL MATERIALS

Next generation organoids for biomedical research and applications

(2018) Yan-Ru Lou et al.   BIOTECHNOLOGY ADVANCES

Human brain organoid-on-a-chip to model prenatal nicotine exposure

(2018) Yaqing Wang et al.   LAB ON A CHIP

Human brain organoids on a chip reveal the physics of folding

(2018) Eyal Karzbrun et al.   Nature Physics

Millifluidic culture improves human midbrain organoid vitality and differentiation

(2018) Emanuel Berger et al.   LAB ON A CHIP

Human stomach-on-a-chip with luminal flow and peristaltic-like motility

(2018) Kang Kug Lee et al.   LAB ON A CHIP

Progress and potential in organoid research

(2018) Giuliana Rossi et al.   NATURE REVIEWS GENETICS

Advances in organ-on-a-chip engineering

(2018) Boyang Zhang et al.   Nature Reviews Materials

Recent Advances in Body-on-a-Chip Systems

(2018) Jong Hwan Sung et al.   ANALYTICAL CHEMISTRY

In situ generation of human brain organoids on a micropillar array

(2017) Yujuan Zhu et al.   LAB ON A CHIP

Synthetic hydrogels mimicking basement membrane matrices to promote cell-matrix interactions

(2017) Ricardo Cruz-Acuña et al.   MATRIX BIOLOGY

Guided self-organization and cortical plate formation in human brain organoids

(2017) Madeline A Lancaster et al.   NATURE BIOTECHNOLOGY

On-chip human microvasculature assay for visualization and quantification of tumor cell extravasation dynamics

(2017) Michelle B Chen et al.   Nature Protocols

Multisensor-integrated organs-on-chips platform for automated and continual in situ monitoring of organoid behaviors

(2017) Yu Shrike Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microphysiological Analysis Platform of Pancreatic Islet β-Cell Spheroids

(2017) Sang Hun Lee et al.   Advanced Healthcare Materials

Multiorgan Microphysiological Systems for Drug Development: Strategies, Advances, and Challenges

(2017) Ying I. Wang et al.   Advanced Healthcare Materials

Multi-tissue interactions in an integrated three-tissue organ-on-a-chip platform

(2017) Aleksander Skardal et al.   Scientific Reports

Brain-Region-Specific Organoids Using Mini-bioreactors for Modeling ZIKV Exposure

(2016) Xuyu Qian et al.   CELL

Engineering Stem Cell Organoids

(2016) Xiaolei Yin et al.   Cell Stem Cell

Development-on-chip:in vitroneural tube patterning with a microfluidic device

(2016) Christopher J. Demers et al.   DEVELOPMENT

Organoids: Modeling Development and the Stem Cell Niche in a Dish

(2016) Kai Kretzschmar et al.   DEVELOPMENTAL CELL

Engineering anastomosis between living capillary networks and endothelial cell-lined microfluidic channels

(2016) Xiaolin Wang et al.   LAB ON A CHIP

Clarifying intact 3D tissues on a microfluidic chip for high-throughput structural analysis

(2016) Yih Yang Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Three-dimensional bioprinting of thick vascularized tissues

(2016) David B. Kolesky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Engineered In Vitro Disease Models

(2015) Kambez H. Benam et al.   Annual Review of Pathology-Mechanisms of Disease

A multilayered microfluidic blood vessel-like structure

(2015) Anwarul Hasan et al.   BIOMEDICAL MICRODEVICES

3D high- and super-resolution imaging using single-objective SPIM

(2015) Remi Galland et al.   NATURE METHODS

Organs-on-chips at the frontiers of drug discovery

(2015) Eric W. Esch et al.   NATURE REVIEWS DRUG DISCOVERY

Preserved genetic diversity in organoids cultured from biopsies of human colorectal cancer metastases

(2015) Fleur Weeber et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microfluidics platform for measurement of volume changes in immobilized intestinal enteroids

(2014) Byung-Ju Jin et al.   Biomicrofluidics

Approaches to in vitro tissue regeneration with application for human disease modeling and drug development

(2014) Mohammad R. Ebrahimkhani et al.   DRUG DISCOVERY TODAY

Organs-on-a-chip: a new tool for drug discovery

(2014) Alessandro Polini et al.   Expert Opinion on Drug Discovery

Hepatic organoids for microfluidic drug screening

(2014) Sam H. Au et al.   LAB ON A CHIP

Microfluidic organs-on-chips

(2014) Sangeeta N Bhatia et al.   NATURE BIOTECHNOLOGY

Organogenesis in a dish: Modeling development and disease using organoid technologies

(2014) M. A. Lancaster et al.   SCIENCE

Physiologically relevant organs on chips

(2013) Kyungsuk Yum et al.   Biotechnology Journal

Next-Generation Regenerative Medicine: Organogenesis from Stem Cells in 3D Culture

(2013) Yoshiki Sasai   Cell Stem Cell

Microfluidic platforms for mechanobiology

(2013) William J. Polacheck et al.   LAB ON A CHIP

Engineering of functional, perfusable 3D microvascular networks on a chip

(2013) Sudong Kim et al.   LAB ON A CHIP

Cerebral organoids model human brain development and microcephaly

(2013) Madeline A. Lancaster et al.   NATURE

Engineers are from PDMS-land, Biologists are from Polystyrenia

(2012) Erwin Berthier et al.   LAB ON A CHIP

Morphogen Gradients: From Generation to Interpretation

(2011) Katherine W. Rogers et al.   Annual Review of Cell and Developmental Biology

From 3D cell culture to organs-on-chips

(2011) Dongeun Huh et al.   TRENDS IN CELL BIOLOGY

Convenient Method for Modifying Poly(dimethylsiloxane) To Be Airtight and Resistive against Absorption of Small Molecules

(2010) Kangning Ren et al.   ANALYTICAL CHEMISTRY

Mechanical control of tissue and organ development

(2010) T. Mammoto et al.   DEVELOPMENT

Reconstituting Organ-Level Lung Functions on a Chip

(2010) D. Huh et al.   SCIENCE