Hepatic organoids for microfluidic drug screening

Paper Microfluidics Goes Digital

(2014) Ryan Fobel et al.   ADVANCED MATERIALS

Correction: Cell Encapsulation in Sub-mm Sized Gel Modules Using Replica Molding

(2014) Alison P. McGuigan et al.   PLoS One

Microgels on-demand

(2014) Irwin A. Eydelnant et al.   Nature Communications

Integrated Digital Microfluidic Platform for Voltammetric Analysis

(2013) Michael D. M. Dryden et al.   ANALYTICAL CHEMISTRY

DropBot: An open-source digital microfluidic control system with precise control of electrostatic driving force and instantaneous drop velocity measurement

(2013) Ryan Fobel et al.   APPLIED PHYSICS LETTERS

Cellular bias on the microscale: probing the effects of digital microfluidic actuation on mammalian cell health, fitness and phenotype

(2013) Sam H. Au et al.   Integrative Biology

Towards personalized medicine with a three-dimensional micro-scale perfusion-based two-chamber tissue model system

(2012) Liang Ma et al.   BIOMATERIALS

Digital microfluidics with impedance sensing for integrated cell culture andanalysis

(2012) Steve C.C. Shih et al.   BIOSENSORS & BIOELECTRONICS

Characterization of primary human hepatocytes, HepG2 cells, and HepaRG cells at the mRNA level and CYP activity in response to inducers and their predictivity for the detection of human hepatotoxins

(2012) H. H. J. Gerets et al.   CELL BIOLOGY AND TOXICOLOGY

Programmable large area digital microfluidic array with integrated droplet sensing for bioassays

(2012) B. Hadwen et al.   LAB ON A CHIP

Microfluidic devices for in vitro studies on liver drug metabolism and toxicity

(2011) Paul M. van Midwoud et al.   Integrative Biology

A digital microfluidic platform for primary cell culture and analysis

(2011) Suthan Srigunapalan et al.   LAB ON A CHIP

A digital microfluidic method for multiplexed cell-based apoptosis assays

(2011) Dario Bogojevic et al.   LAB ON A CHIP

A New Angle on Pluronic Additives: Advancing Droplets and Understanding in Digital Microfluidics

(2011) Sam H. Au et al.   LANGMUIR

Bioprinting cell-laden matrigel for radioprotection study of liver by pro-drug conversion in a dual-tissue microfluidic chip

(2011) J E Snyder et al.   Biofabrication

Integrated microbioreactor for culture and analysis of bacteria, algae and yeast

(2010) Sam H. Au et al.   BIOMEDICAL MICRODEVICES

Principles of early drug discovery

(2010) JP Hughes et al.   BRITISH JOURNAL OF PHARMACOLOGY

Evaluation of drug toxicity with hepatocytes cultured in a micro-space cell culture system

(2010) Kazuaki Nakamura et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Perfusion-based microfluidic device for three-dimensional dynamic primary human hepatocyte cell culture in the absence of biological or synthetic matrices or coagulants

(2010) Vasiliy N. Goral et al.   LAB ON A CHIP

Microfluidic synthesis of pure chitosan microfibers for bio-artificial liver chip

(2010) Kwang Ho Lee et al.   LAB ON A CHIP

A microfluidic platform for complete mammalian cell culture

(2010) Irena Barbulovic-Nad et al.   LAB ON A CHIP

Fabrication of three-dimensional porous cell-laden hydrogel for tissue engineering

(2010) Chang Mo Hwang et al.   Biofabrication

Hydrogels as extracellular matrix mimics for 3D cell culture

(2009) Mark W. Tibbitt et al.   BIOTECHNOLOGY AND BIOENGINEERING

The impact of cytokines on the expression of drug transporters, cytochrome P450 enzymes and chemokine receptors in human PBMC

(2009) NJ Liptrott et al.   BRITISH JOURNAL OF PHARMACOLOGY

Towards a human-on-chip: Culturing multiple cell types on a chip with compartmentalized microenvironments

(2009) Chi Zhang et al.   LAB ON A CHIP

A microfluidic 3D hepatocyte chip for drug toxicity testing

(2009) Yi-Chin Toh et al.   LAB ON A CHIP

Droplet-Scale Estrogen Assays in Breast Tissue, Blood, and Serum

(2009) N. A. Mousa et al.   Science Translational Medicine

Albumin Usage in Clinical Medicine: Tradition or Therapeutic?

(2009) Albert Farrugia   TRANSFUSION MEDICINE REVIEWS

The role of matrix stiffness in regulating cell behavior

(2008) Rebecca G. Wells   HEPATOLOGY

Cross-scale electric manipulations of cells and droplets by frequency-modulated dielectrophoresis and electrowetting

(2008) Shih-Kang Fan et al.   LAB ON A CHIP

Digital microfluidics for cell-based assays

(2008) Irena Barbulovic-Nad et al.   LAB ON A CHIP

CHEMISTRY: Putting Electrowetting to Work

(2008) A. R. Wheeler   SCIENCE

Monolayer and Spheroid Culture of Human Liver Hepatocellular Carcinoma Cell Line Cells Demonstrate Distinct Global Gene Expression Patterns and Functional Phenotypes

(2008) Tammy T. Chang et al.   TISSUE ENGINEERING PART A

Development of a Microscale Cell Culture Analog To Probe Naphthalene Toxicity

(2004) Kwanchanok Viravaidya et al.   BIOTECHNOLOGY PROGRESS