Human brain organoids on a chip reveal the physics of folding

Guided self-organization and cortical plate formation in human brain organoids

(2017) Madeline A Lancaster et al.   NATURE BIOTECHNOLOGY

The use of brain organoids to investigate neural development and disease

(2017) Elizabeth Di Lullo et al.   NATURE REVIEWS NEUROSCIENCE

Single-Cell Profiling of an In Vitro Model of Human Interneuron Development Reveals Temporal Dynamics of Cell Type Production and Maturation

(2017) Jennie L. Close et al.   NEURON

A normative spatiotemporal MRI atlas of the fetal brain for automatic segmentation and analysis of early brain growth

(2017) Ali Gholipour et al.   Scientific Reports

Modeling Development and Disease with Organoids

(2016) Hans Clevers   CELL

Emerging roles for motor proteins in progenitor cell behavior and neuronal migration during brain development

(2016) Tiago J. Dantas et al.   Cytoskeleton

On the growth and form of cortical convolutions

(2016) Tuomas Tallinen et al.   Nature Physics

GeneAnalytics: An Integrative Gene Set Analysis Tool for Next Generation Sequencing, RNAseq and Microarray Data

(2016) Shani Ben-Ari Fuchs et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

3D spherical microtissues and microfluidic technology for multi-tissue experiments and analysis

(2015) Jin-Young Kim et al.   JOURNAL OF BIOTECHNOLOGY

Functional cortical neurons and astrocytes from human pluripotent stem cells in 3D culture

(2015) Anca M Paşca et al.   NATURE METHODS

Single-cell analysis reveals transcriptional heterogeneity of neural progenitors in human cortex

(2015) Matthew B Johnson et al.   NATURE NEUROSCIENCE

Cortical folding scales universally with surface area and thickness, not number of neurons

(2015) B. Mota et al.   SCIENCE

Human-specific gene ARHGAP11B promotes basal progenitor amplification and neocortex expansion

(2015) M. Florio et al.   SCIENCE

If Cell Mechanics Can Be Described by Elastic Modulus: Study of Different Models and Probes Used in Indentation Experiments

(2014) Nataliia Guz et al.   BIOPHYSICAL JOURNAL

Morphomechanics: transforming tubes into organs

(2014) Larry A Taber   CURRENT OPINION IN GENETICS & DEVELOPMENT

Neural progenitors, neurogenesis and the evolution of the neocortex

(2014) M. Florio et al.   DEVELOPMENT

Radial glia require PDGFD–PDGFRβ signalling in human but not mouse neocortex

(2014) Jan H. Lui et al.   NATURE

Molecular and functional definition of the developing human striatum

(2014) Marco Onorati et al.   NATURE NEUROSCIENCE

Growth and folding of the mammalian cerebral cortex: from molecules to malformations

(2014) Tao Sun et al.   NATURE REVIEWS NEUROSCIENCE

Gyrification from constrained cortical expansion

(2014) T. Tallinen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Massively Parallel Single-Cell RNA-Seq for Marker-Free Decomposition of Tissues into Cell Types

(2014) D. A. Jaitin et al.   SCIENCE

LIS1 functions in normal development and disease

(2013) Orly Reiner et al.   CURRENT OPINION IN NEUROBIOLOGY

Apical constriction initiates new bud formation during monopodial branching of the embryonic chicken lung

(2013) H. Y. Kim et al.   DEVELOPMENT

Derivation of novel human ground state naive pluripotent stem cells

(2013) Ohad Gafni et al.   NATURE

Cerebral organoids model human brain development and microcephaly

(2013) Madeline A. Lancaster et al.   NATURE

Medial ganglionic eminence–like cells derived from human embryonic stem cells correct learning and memory deficits

(2013) Yan Liu et al.   NATURE BIOTECHNOLOGY

Subcortical origins of human and monkey neocortical interneurons

(2013) Tong Ma et al.   NATURE NEUROSCIENCE

Fate Mapping by PiggyBac Transposase Reveals That Neocortical GLAST+ Progenitors Generate More Astrocytes Than Nestin+ Progenitors in Rat Neocortex

(2012) F. Siddiqi et al.   CEREBRAL CORTEX

Lis1 is an initiation factor for dynein-driven organelle transport

(2012) Martin J. Egan et al.   JOURNAL OF CELL BIOLOGY

Concentration landscape generators for shear free dynamic chemical stimulation

(2012) Mathieu Morel et al.   LAB ON A CHIP

Human cerebral cortex development from pluripotent stem cells to functional excitatory synapses

(2012) Yichen Shi et al.   NATURE NEUROSCIENCE

Mechanical Instabilities of Biological Tubes

(2012) Edouard Hannezo et al.   PHYSICAL REVIEW LETTERS

Transcriptomes of germinal zones of human and mouse fetal neocortex suggest a role of extracellular matrix in progenitor self-renewal

(2012) S. A. Fietz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

On the growth and form of the gut

(2011) Thierry Savin et al.   NATURE

Shape Transition in Artificial Tumors: From Smooth Buckles to Singular Creases

(2011) Julien Dervaux et al.   PHYSICAL REVIEW LETTERS

ROAST: rotation gene set tests for complex microarray experiments

(2010) Di Wu et al.   BIOINFORMATICS

Multilayer microfluidic PEGDA hydrogels

(2010) Michael P. Cuchiara et al.   BIOMATERIALS

LIS1 and NudE Induce a Persistent Dynein Force-Producing State

(2010) Richard J. McKenney et al.   CELL

A Role for Intermediate Radial Glia in the Tangential Expansion of the Mammalian Cerebral Cortex

(2010) Isabel Reillo et al.   CEREBRAL CORTEX

Molecular Interactions in Surface-Assembled Monolayers of Short Double-Stranded DNA

(2010) Ling Huang et al.   LANGMUIR

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

Increased LIS1 expression affects human and mouse brain development

(2009) Weimin Bi et al.   NATURE GENETICS

Regulators of the cytoplasmic dynein motor

(2009) Julia R. Kardon et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Myosin II is required for interkinetic nuclear migration of neural progenitors

(2009) J. Schenk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Self-Organized Formation of Polarized Cortical Tissues from ESCs and Its Active Manipulation by Extrinsic Signals

(2008) Mototsugu Eiraku et al.   Cell Stem Cell

Formation of the zebrafish midbrain–hindbrain boundary constriction requires laminin-dependent basal constriction

(2008) Jennifer H. Gutzman et al.   MECHANISMS OF DEVELOPMENT

The genetics of early telencephalon patterning: some assembly required

(2008) Jean M. Hébert et al.   NATURE REVIEWS NEUROSCIENCE