Microfluidics platform for measurement of volume changes in immobilized intestinal enteroids

Study of flow behaviors on single-cell manipulation and shear stress reduction in microfluidic chips using computational fluid dynamics simulations

(2014) Feng Shen et al.   Biomicrofluidics

Quantifying the volume of single cells continuously using a microfluidic pressure-driven trap with media exchange

(2014) Jason Riordon et al.   Biomicrofluidics

Intestinal organoids as tissue surrogates for toxicological and pharmacological studies

(2013) Anton Kuratnik et al.   BIOCHEMICAL PHARMACOLOGY

A microfluidic device for uniform-sized cell spheroids formation, culture, harvesting and flow cytometry analysis

(2013) Bishnubrata Patra et al.   Biomicrofluidics

Functional Repair of CFTR by CRISPR/Cas9 in Intestinal Stem Cell Organoids of Cystic Fibrosis Patients

(2013) Gerald Schwank et al.   Cell Stem Cell

A functional CFTR assay using primary cystic fibrosis intestinal organoids

(2013) Johanna F Dekkers et al.   NATURE MEDICINE

Growing Self-Organizing Mini-Guts from a Single Intestinal Stem Cell: Mechanism and Applications

(2013) T. Sato et al.   SCIENCE

Use of Collagen Gel as an Alternative Extracellular Matrix for the In Vitro and In Vivo Growth of Murine Small Intestinal Epithelium

(2013) Ziyad Jabaji et al.   TISSUE ENGINEERING PART C-METHODS

Functional Cftr in crypt epithelium of organotypic enteroid cultures from murine small intestine

(2012) Jinghua Liu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

CFTR Inhibitors for Treating Diarrheal Disease

(2012) J R Thiagarajah et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Intestinal crypts reproducibly expand in culture

(2012) Megan K. Fuller et al.   JOURNAL OF SURGICAL RESEARCH

Aquaporins in Clinical Medicine

(2011) A.S. Verkman   Annual Review of Medicine

Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium

(2011) Toshiro Sato et al.   GASTROENTEROLOGY

Droplet-based microfluidic system for multicellular tumor spheroid formation and anticancer drug testing

(2010) Linfen Yu et al.   LAB ON A CHIP

A multicellular spheroid formation and extraction chip using removable cell trapping barriers

(2010) Hye-Jin Jin et al.   LAB ON A CHIP

Subcooled convective boiling in structured surface microchannels

(2009) Shou-Shing Hsieh et al.   JOURNAL OF MICROMECHANICS AND MICROENGINEERING

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

(2009) Toshiro Sato et al.   NATURE