- Home
- Publications
- Publication Search
- Publication Details
Title
Role of the endolysosomal system in Parkinson’s disease
Authors
Keywords
-
Journal
JOURNAL OF NEUROCHEMISTRY
Volume -, Issue -, Pages -
Publisher
Wiley
Online
2019-07-10
DOI
10.1111/jnc.14820
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- α-Synuclein: A Multifunctional Player in Exocytosis, Endocytosis, and Vesicle Recycling
- (2019) Mingzhu Huang et al. Frontiers in Neuroscience
- The genetics of Parkinson disease
- (2018) Hao Deng et al. AGEING RESEARCH REVIEWS
- The Parkinson's disease VPS35[D620N] mutation enhances LRRK2-mediated Rab protein phosphorylation in mouse and human
- (2018) Rafeeq Mir et al. BIOCHEMICAL JOURNAL
- Phospholipase PLA2G6, a Parkinsonism-Associated Gene, Affects Vps26 and Vps35, Retromer Function, and Ceramide Levels, Similar to α-Synuclein Gain
- (2018) Guang Lin et al. Cell Metabolism
- Diagnostic exome sequencing in early-onset Parkinson's disease confirms VPS13C as a rare cause of autosomal-recessive Parkinson's disease
- (2018) B. Schormair et al. CLINICAL GENETICS
- Endo-lysosomal dysfunction: a converging mechanism in neurodegenerative diseases
- (2018) Chao Wang et al. CURRENT OPINION IN NEUROBIOLOGY
- Parkin mediates the ubiquitination of VPS35 and modulates retromer-dependent endosomal sorting
- (2018) Erin T Williams et al. HUMAN MOLECULAR GENETICS
- Neurodegenerative diseases: model organisms, pathology and autophagy
- (2018) S. N. Suresh et al. JOURNAL OF GENETICS
- Glycosphingolipid levels and glucocerebrosidase activity are altered in normal aging of the mouse brain
- (2018) Penelope J. Hallett et al. NEUROBIOLOGY OF AGING
- Internalization, axonal transport and release of fibrillar forms of alpha-synuclein
- (2018) Gregor Bieri et al. NEUROBIOLOGY OF DISEASE
- Familial knockin mutation of LRRK2 causes lysosomal dysfunction and accumulation of endogenous insoluble α-synuclein in neurons
- (2018) Jason Schapansky et al. NEUROBIOLOGY OF DISEASE
- Synaptojanin and Endophilin Mediate Neck Formation during Ultrafast Endocytosis
- (2018) Shigeki Watanabe et al. NEURON
- Reversible Conformational Conversion of α-Synuclein into Toxic Assemblies by Glucosylceramide
- (2018) Friederike Zunke et al. NEURON
- Autophagy at the synapse
- (2018) Veronica Birdsall et al. NEUROSCIENCE LETTERS
- LRRK2 phosphorylation of auxilin mediates synaptic defects in dopaminergic neurons from patients with Parkinson’s disease
- (2018) Maria Nguyen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Regulation and Roles of Autophagy at Synapses
- (2018) Vassiliki Nikoletopoulou et al. TRENDS IN CELL BIOLOGY
- Modulation of Autophagy by a Small Molecule Inverse Agonist of ERRα Is Neuroprotective
- (2018) S. N. Suresh et al. Frontiers in Molecular Neuroscience
- Import and Export of Misfolded α-Synuclein
- (2018) Lilia Rodriguez et al. Frontiers in Neuroscience
- Centrality of Early Synaptopathy in Parkinson’s Disease
- (2018) Paola Imbriani et al. Frontiers in Neurology
- VPS13A and VPS13C are lipid transport proteins differentially localized at ER contact sites
- (2018) Nikit Kumar et al. JOURNAL OF CELL BIOLOGY
- Endosomal sorting and trafficking, the retromer complex and neurodegeneration
- (2018) Alana N. Vagnozzi et al. MOLECULAR PSYCHIATRY
- Therapeutic strategies for Parkinson disease: beyond dopaminergic drugs
- (2018) Delphine Charvin et al. NATURE REVIEWS DRUG DISCOVERY
- LRRK2 and its substrate Rab GTPases are sequentially targeted onto stressed lysosomes and maintain their homeostasis
- (2018) Tomoya Eguchi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- LRRK2 kinase regulates α-synuclein propagation via RAB35 phosphorylation
- (2018) Eun-Jin Bae et al. Nature Communications
- Admixing MPTP-resistant and MPTP-vulnerable mice enhances striatal field potentials and calbindin-D28K expression to avert motor behaviour deficits
- (2018) D.J. Vidyadhara et al. BEHAVIOURAL BRAIN RESEARCH
- Vps35 in cooperation with LRRK2 regulates synaptic vesicle endocytosis through the endosomal pathway in Drosophila
- (2017) Tsuyoshi Inoshita et al. HUMAN MOLECULAR GENETICS
- Selective imaging of internalized proteopathic α-synuclein seeds in primary neurons reveals mechanistic insight into transmission of synucleinopathies
- (2017) Richard J. Karpowicz et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Vps13p–Cdc31p complex is directly required for TGN late endosome transport and TGN homotypic fusion
- (2017) Mithu De et al. JOURNAL OF CELL BIOLOGY
- Glucosylsphingosine Promotes α-Synuclein Pathology in Mutant GBA-Associated Parkinson's Disease
- (2017) Yumiko V. Taguchi et al. JOURNAL OF NEUROSCIENCE
- Wild-Type Monomeric α-Synuclein Can Impair Vesicle Endocytosis and Synaptic Fidelity via Tubulin Polymerization at the Calyx of Held
- (2017) Kohgaku Eguchi et al. JOURNAL OF NEUROSCIENCE
- Parkinson's Disease-Associated LRRK2 Hyperactive Kinase Mutant Disrupts Synaptic Vesicle Trafficking in Ventral Midbrain Neurons
- (2017) Ping-Yue Pan et al. JOURNAL OF NEUROSCIENCE
- Quantitative proteomic analysis of Parkin substrates in Drosophila neurons
- (2017) Aitor Martinez et al. Molecular Neurodegeneration
- A meta-analysis of genome-wide association studies identifies 17 new Parkinson's disease risk loci
- (2017) Diana Chang et al. NATURE GENETICS
- α-Synuclein promotes dilation of the exocytotic fusion pore
- (2017) Todd Logan et al. NATURE NEUROSCIENCE
- Selective neuronal vulnerability in Parkinson disease
- (2017) D. James Surmeier et al. NATURE REVIEWS NEUROSCIENCE
- Parkinson Sac Domain Mutation in Synaptojanin 1 Impairs Clathrin Uncoating at Synapses and Triggers Dystrophic Changes in Dopaminergic Axons
- (2017) Mian Cao et al. NEURON
- Glucosylceramide synthase inhibition alleviates aberrations in synucleinopathy models
- (2017) S. Pablo Sardi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- TMEM175 deficiency impairs lysosomal and mitochondrial function and increases α-synuclein aggregation
- (2017) Sarah Jinn et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- SNX-1 and RME-8 oppose the assembly of HGRS-1/ESCRT-0 degradative microdomains on endosomes
- (2017) Anne Norris et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- α-Synuclein – Regulator of Exocytosis, Endocytosis, or Both?
- (2017) Janin Lautenschläger et al. TRENDS IN CELL BIOLOGY
- Spatial and Temporal Regulation of Receptor Endocytosis in Neuronal Dendrites Revealed by Imaging of Single Vesicle Formation
- (2017) Morgane Rosendale et al. Cell Reports
- Synucleins Have Multiple Effects on Presynaptic Architecture
- (2017) Karina J. Vargas et al. Cell Reports
- Auxilin Underlies Progressive Locomotor Deficits and Dopaminergic Neuron Loss in a Drosophila Model of Parkinson’s Disease
- (2017) Li Song et al. Cell Reports
- VPS35, the Retromer Complex and Parkinson’s Disease
- (2017) Erin T. Williams et al. Journal of Parkinsons Disease
- Systematic proteomic analysis of LRRK2-mediated Rab GTPase phosphorylation establishes a connection to ciliogenesis
- (2017) Martin Steger et al. eLife
- The Role of Co-chaperones in Synaptic Proteostasis and Neurodegenerative Disease
- (2017) Erica L. Gorenberg et al. Frontiers in Neuroscience
- In Situ Peroxidase Labeling and Mass-Spectrometry Connects Alpha-Synuclein Directly to Endocytic Trafficking and mRNA Metabolism in Neurons
- (2017) Chee Yeun Chung et al. Cell Systems
- Parkinson disease
- (2017) Werner Poewe et al. Nature Reviews Disease Primers
- Cellular internalization of alpha-synuclein aggregates by cell surface heparan sulfate depends on aggregate conformation and cell type
- (2017) Elisabet Ihse et al. Scientific Reports
- Axonal transport and secretion of fibrillar forms of α-synuclein, Aβ42 peptide and HTTExon 1
- (2016) Michel Brahic et al. ACTA NEUROPATHOLOGICA
- Loss of VPS13C Function in Autosomal-Recessive Parkinsonism Causes Mitochondrial Dysfunction and Increases PINK1/Parkin-Dependent Mitophagy
- (2016) Suzanne Lesage et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Specifically neuropathic Gaucher's mutations accelerate cognitive decline in Parkinson's
- (2016) Ganqiang Liu et al. ANNALS OF NEUROLOGY
- D NAJC 6 Mutations Associated With Early-Onset Parkinson's Disease
- (2016) Simone Olgiati et al. ANNALS OF NEUROLOGY
- DnaJ/Hsc70 chaperone complexes control the extracellular release of neurodegenerative‐associated proteins
- (2016) Sarah N Fontaine et al. EMBO JOURNAL
- Parkinson Disease-linked Vps35 R524W Mutation Impairs the Endosomal Association of Retromer and Induces α-Synuclein Aggregation
- (2016) Jordan Follett et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Differential expression of calbindin in nigral dopaminergic neurons in two mice strains with differential susceptibility to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
- (2016) D.J. Vidyadhara et al. JOURNAL OF CHEMICAL NEUROANATOMY
- -Synuclein Mutation Inhibits Endocytosis at Mammalian Central Nerve Terminals
- (2016) J. Xu et al. JOURNAL OF NEUROSCIENCE
- Altered Development of Synapse Structure and Function in Striatum Caused by Parkinson's Disease-Linked LRRK2-G2019S Mutation
- (2016) B. A. Matikainen-Ankney et al. JOURNAL OF NEUROSCIENCE
- Parkin Modulates Endosomal Organization and Function of the Endo-Lysosomal Pathway
- (2016) Pingping Song et al. JOURNAL OF NEUROSCIENCE
- Admixing of MPTP-Resistant and Susceptible Mice Strains Augments Nigrostriatal Neuronal Correlates to Resist MPTP-Induced Neurodegeneration
- (2016) D. J. Vidyadhara et al. MOLECULAR NEUROBIOLOGY
- LRRK2 phosphorylates pre-synaptic N-ethylmaleimide sensitive fusion (NSF) protein enhancing its ATPase activity and SNARE complex disassembling rate
- (2016) Elisa Belluzzi et al. Molecular Neurodegeneration
- Endolysosomal dysfunction in Parkinson's disease: Recent developments and future challenges
- (2016) Lauren R. Kett et al. MOVEMENT DISORDERS
- Unconventional secretion of misfolded proteins promotes adaptation to proteasome dysfunction in mammalian cells
- (2016) Jin-Gu Lee et al. NATURE CELL BIOLOGY
- Identification of TMEM230 mutations in familial Parkinson's disease
- (2016) Han-Xiang Deng et al. NATURE GENETICS
- A LRRK2-Dependent EndophilinA Phosphoswitch Is Critical for Macroautophagy at Presynaptic Terminals
- (2016) Sandra-Fausia Soukup et al. NEURON
- Pathological -synuclein transmission initiated by binding lymphocyte-activation gene 3
- (2016) X. Mao et al. SCIENCE
- Deciphering the Molecular Signals of PINK1/Parkin Mitophagy
- (2016) Thanh N. Nguyen et al. TRENDS IN CELL BIOLOGY
- Endophilin-A Deficiency Induces the Foxo3a-Fbxo32 Network in the Brain and Causes Dysregulation of Autophagy and the Ubiquitin-Proteasome System
- (2016) John D. Murdoch et al. Cell Reports
- Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases
- (2016) Martin Steger et al. eLife
- ER Stress and Autophagic Perturbations Lead to Elevated Extracellular α-Synuclein in GBA-N370S Parkinson's iPSC-Derived Dopamine Neurons
- (2016) Hugo J.R. Fernandes et al. Stem Cell Reports
- LRRK2 and RAB7L1 coordinately regulate axonal morphology and lysosome integrity in diverse cellular contexts
- (2016) Tomoki Kuwahara et al. Scientific Reports
- Glucocerebrosidase activity in Parkinson’s disease with and withoutGBAmutations
- (2015) Roy N. Alcalay et al. BRAIN
- -synuclein assemblies sequester neuronal 3-Na+/K+-ATPase and impair Na+ gradient
- (2015) A. N. Shrivastava et al. EMBO JOURNAL
- Phosphoproteomic screening identifies Rab GTPases as novel downstream targets of PINK1
- (2015) Y.-C. Lai et al. EMBO JOURNAL
- VPS35pathogenic mutations confer no dominant toxicity but partial loss of function inDrosophilaand genetically interact withparkin
- (2015) Bilal R. Malik et al. HUMAN MOLECULAR GENETICS
- Autophagosome dynamics in neurodegeneration at a glance
- (2015) Y. C. Wong et al. JOURNAL OF CELL SCIENCE
- -Synuclein-Independent Histopathological and Motor Deficits in Mice Lacking the Endolysosomal Parkinsonism Protein Atp13a2
- (2015) L. R. Kett et al. JOURNAL OF NEUROSCIENCE
- VPS35 in Dopamine Neurons Is Required for Endosome-to-Golgi Retrieval of Lamp2a, a Receptor of Chaperone-Mediated Autophagy That Is Critical for -Synuclein Degradation and Prevention of Pathogenesis of Parkinson's Disease
- (2015) F.-L. Tang et al. JOURNAL OF NEUROSCIENCE
- GBAVariants are associated with a distinct pattern of cognitive deficits in Parkinson's disease
- (2015) Ignacio F. Mata et al. MOVEMENT DISORDERS
- Parkinson's disease–associated mutant VPS35 causes mitochondrial dysfunction by recycling DLP1 complexes
- (2015) Wenzhang Wang et al. NATURE MEDICINE
- Aging causes morphological alterations in astrocytes and microglia in human substantia nigra pars compacta
- (2015) H.J. Jyothi et al. NEUROBIOLOGY OF AGING
- An early axonopathy in a hLRRK2(R1441G) transgenic model of Parkinson disease
- (2015) Patricia Tagliaferro et al. NEUROBIOLOGY OF DISEASE
- The Roles of PINK1, Parkin, and Mitochondrial Fidelity in Parkinson’s Disease
- (2015) Alicia M. Pickrell et al. NEURON
- Massive accumulation of luminal protease-deficient axonal lysosomes at Alzheimer’s disease amyloid plaques
- (2015) Swetha Gowrishankar et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- VPS35 Deficiency or Mutation Causes Dopaminergic Neuronal Loss by Impairing Mitochondrial Fusion and Function
- (2015) Fu-Lei Tang et al. Cell Reports
- The Synaptic Function of α-Synuclein
- (2015) Jacqueline Burré Journal of Parkinsons Disease
- Alpha-synuclein degradation by autophagic pathways: A potential key to Parkinson’s Disease pathogenesis
- (2014) Maria Xilouri et al. Autophagy
- A new pathway for mitochondrial quality control: mitochondrial-derived vesicles
- (2014) A. Sugiura et al. EMBO JOURNAL
- LRRK2 localizes to endosomes and interacts with clathrin-light chains to limit Rac1 activation
- (2014) A. M. Schreij et al. EMBO REPORTS
- Dense Core Vesicle Release: Controlling the Where as Well as the When
- (2014) S. Nurrish GENETICS
- Retromer-dependent neurotransmitter receptor trafficking to synapses is altered by the Parkinson's disease VPS35 mutation p.D620N
- (2014) L. N. Munsie et al. HUMAN MOLECULAR GENETICS
- Mitophagy of damaged mitochondria occurs locally in distal neuronal axons and requires PINK1 and Parkin
- (2014) Ghazaleh Ashrafi et al. JOURNAL OF CELL BIOLOGY
- PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity
- (2014) Lesley A. Kane et al. JOURNAL OF CELL BIOLOGY
- Dysregulation of lysosomal morphology by pathogenic LRRK2 is corrected by TPC2 inhibition
- (2014) L. N. Hockey et al. JOURNAL OF CELL SCIENCE
- Upregulation of Parkin in Endophilin Mutant Mice
- (2014) Mian Cao et al. JOURNAL OF NEUROSCIENCE
- ATP13A2/PARK9 Regulates Secretion of Exosomes and -Synuclein
- (2014) T. Tsunemi et al. JOURNAL OF NEUROSCIENCE
- Synucleins Regulate the Kinetics of Synaptic Vesicle Endocytosis
- (2014) K. J. Vargas et al. JOURNAL OF NEUROSCIENCE
- Presynaptic Alpha-Synuclein Aggregation in a Mouse Model of Parkinson's Disease
- (2014) K. J. Spinelli et al. JOURNAL OF NEUROSCIENCE
- Acute increase of α-synuclein inhibits synaptic vesicle recycling evoked during intense stimulation
- (2014) David J. Busch et al. MOLECULAR BIOLOGY OF THE CELL
- Vacuolar protein sorting 35 (Vps35) rescues locomotor deficits and shortened lifespan in Drosophila expressing a Parkinson’s disease mutant of Leucine-rich repeat kinase 2 (LRRK2)
- (2014) Radek Linhart et al. Molecular Neurodegeneration
- DNAJC13genetic variants in parkinsonism
- (2014) Emil K. Gustavsson et al. MOVEMENT DISORDERS
- Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease
- (2014) Mike A Nalls et al. NATURE GENETICS
- LRRK2 regulates synaptogenesis and dopamine receptor activation through modulation of PKA activity
- (2014) Loukia Parisiadou et al. NATURE NEUROSCIENCE
- PARK20 caused by SYNJ1 homozygous Arg258Gln mutation in a new Italian family
- (2014) Simone Olgiati et al. NEUROGENETICS
- Axonal Transport: Cargo-Specific Mechanisms of Motility and Regulation
- (2014) Sandra Maday et al. NEURON
- A GCase Chaperone Improves Motor Function in a Mouse Model of Synucleinopathy
- (2014) Franziska Richter et al. Neurotherapeutics
- The Complex Ultrastructure of the Endolysosomal System
- (2014) J. Klumperman et al. Cold Spring Harbor Perspectives in Biology
- The LRRK2 inhibitor GSK2578215A induces protective autophagy in SH-SY5Y cells: involvement of Drp-1-mediated mitochondrial fission and mitochondrial-derived ROS signaling
- (2014) S Saez-Atienzar et al. Cell Death & Disease
- Mutation in VPS35 associated with Parkinson’s disease impairs WASH complex association and inhibits autophagy
- (2014) Eszter Zavodszky et al. Nature Communications
- Inhibition of LRRK2 kinase activity stimulates macroautophagy
- (2013) Claudia Manzoni et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Disease duration and the integrity of the nigrostriatal system in Parkinson’s disease
- (2013) Jeffrey H. Kordower et al. BRAIN
- Historical landmarks of autophagy research
- (2013) Yoshinori Ohsumi CELL RESEARCH
- DNAJC13 mutations in Parkinson disease
- (2013) Carles Vilariño-Güell et al. HUMAN MOLECULAR GENETICS
- Mutation in theSYNJ1Gene Associated with Autosomal Recessive, Early-Onset Parkinsonism
- (2013) Marialuisa Quadri et al. HUMAN MUTATION
- The Sac1 Domain ofSYNJ1Identified Mutated in a Family with Early-Onset Progressive Parkinsonism with Generalized Seizures
- (2013) Catharine E. Krebs et al. HUMAN MUTATION
- Pathogenic Mutation in VPS35 Impairs Its Protection against MPP+ Cytotoxicity
- (2013) Fangfang Bi et al. International Journal of Biological Sciences
- The Clathrin-Dependent Localization of Dopamine Transporter to Surface Membranes Is Affected by α-Synuclein
- (2013) Haya Kisos et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- Parkin disease and the Lewy body conundrum
- (2013) Karen M. Doherty et al. MOVEMENT DISORDERS
- The role of autophagy in neurodegenerative disease
- (2013) Ralph A Nixon NATURE MEDICINE
- Interplay of LRRK2 with chaperone-mediated autophagy
- (2013) Samantha J Orenstein et al. NATURE NEUROSCIENCE
- RAB7L1 Interacts with LRRK2 to Modify Intraneuronal Protein Sorting and Parkinson’s Disease Risk
- (2013) David A. MacLeod et al. NEURON
- Heparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seeds
- (2013) B. B. Holmes et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Autophagy in axonal and dendritic degeneration
- (2013) Yi Yang et al. TRENDS IN NEUROSCIENCES
- The Endolysosomal System in Cell Death and Survival
- (2013) U. Repnik et al. Cold Spring Harbor Perspectives in Biology
- Leucine-Rich Repeat Kinase 2 for Beginners: Six Key Questions
- (2013) L. R. Kett et al. Cold Spring Harbor Perspectives in Medicine
- The Role of Autophagy in Parkinson's Disease
- (2013) M. A. Lynch-Day et al. Cold Spring Harbor Perspectives in Medicine
- Native α-synuclein induces clustering of synaptic-vesicle mimics via binding to phospholipids and synaptobrevin-2/VAMP2
- (2013) Jiajie Diao et al. eLife
- Glucocerebrosidase deficiency in substantia nigra of parkinson disease brains
- (2012) Matthew E. Gegg et al. ANNALS OF NEUROLOGY
- The MAPK1/3 pathway is essential for the deregulation of autophagy observed in G2019S LRRK2 mutant fibroblasts
- (2012) José M. Bravo-San Pedro et al. Autophagy
- SnapShot: Membrane Curvature Sensors and Generators
- (2012) Hongying Shen et al. CELL
- The LRRK2 G2019S mutant exacerbates basal autophagy through activation of the MEK/ERK pathway
- (2012) José M. Bravo-San Pedro et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Monomeric Synucleins Generate Membrane Curvature
- (2012) Christopher H. Westphal et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The link between the GBA gene and parkinsonism
- (2012) Ellen Sidransky et al. LANCET NEUROLOGY
- Clathrin and phosphatidylinositol-4,5-bisphosphate regulate autophagic lysosome reformation
- (2012) Yueguang Rong et al. NATURE CELL BIOLOGY
- LRRK2 Controls an EndoA Phosphorylation Cycle in Synaptic Endocytosis
- (2012) Samer Matta et al. NEURON
- Regulation of Presynaptic Neurotransmission by Macroautophagy
- (2012) Daniela Hernandez et al. NEURON
- DNAJC6 is responsible for juvenile parkinsonism with phenotypic variability
- (2012) Çiğdem Köroğlu et al. PARKINSONISM & RELATED DISORDERS
- A Deleterious Mutation in DNAJC6 Encoding the Neuronal-Specific Clathrin-Uncoating Co-Chaperone Auxilin, Is Associated with Juvenile Parkinsonism
- (2012) Simon Edvardson et al. PLoS One
- Loss of P-type ATPase ATP13A2/PARK9 function induces general lysosomal deficiency and leads to Parkinson disease neurodegeneration
- (2012) B. Dehay et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pathological -Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice
- (2012) K. C. Luk et al. SCIENCE
- Synaptic Vesicle Endocytosis
- (2012) Y. Saheki et al. Cold Spring Harbor Perspectives in Biology
- VPS35 Mutations in Parkinson Disease
- (2011) Carles Vilariño-Güell et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Acid β-glucosidase mutants linked to gaucher disease, parkinson disease, and lewy body dementia alter α-synuclein processing
- (2011) Valerie Cullen et al. ANNALS OF NEUROLOGY
- Novel mutation in ATP13A2 widens the spectrum of Kufor-Rakeb syndrome (PARK9)
- (2011) H Eiberg et al. CLINICAL GENETICS
- Pathogenic effects of novel mutations in the P-type ATPase ATP13A2 (PARK9) causing Kufor-Rakeb syndrome, a form of early-onset parkinsonism
- (2011) Jin-Sung Park et al. HUMAN MUTATION
- Recruitment of Endophilin to Clathrin-Coated Pit Necks Is Required for Efficient Vesicle Uncoating after Fission
- (2011) Ira Milosevic et al. NEURON
- Effects of Curvature and Composition on α-Synuclein Binding to Lipid Vesicles
- (2010) Elizabeth R. Middleton et al. BIOPHYSICAL JOURNAL
- Profile of Cognitive Impairment in Parkinson's Disease
- (2010) G. Stennis Watson et al. BRAIN PATHOLOGY
- Endophilin Functions as a Membrane-Bending Molecule and Is Delivered to Endocytic Zones by Exocytosis
- (2010) Jihong Bai et al. CELL
- α-Synuclein impairs macroautophagy: implications for Parkinson’s disease
- (2010) Ashley R. Winslow et al. JOURNAL OF CELL BIOLOGY
- The risk of Parkinson’s disease in type 1 Gaucher disease
- (2010) Gilberto Bultron et al. JOURNAL OF INHERITED METABOLIC DISEASE
- Increased Expression of α-Synuclein Reduces Neurotransmitter Release by Inhibiting Synaptic Vesicle Reclustering after Endocytosis
- (2010) Venu M. Nemani et al. NEURON
- -Synuclein triple knockout mice reveal age-dependent neuronal dysfunction
- (2010) B. Greten-Harrison et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Endocytosis and clathrin-uncoating defects at synapses of auxilin knockout mice
- (2010) Y.-I. Yim et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin
- (2010) Derek P. Narendra et al. PLOS BIOLOGY
- LRRK2 regulates autophagic activity and localizes to specific membrane microdomains in a novel human genomic reporter cellular model
- (2009) Javier Alegre-Abarrategui et al. HUMAN MOLECULAR GENETICS
- The ESCRT machinery at a glance
- (2009) T. Wollert et al. JOURNAL OF CELL SCIENCE
- Non-motor symptoms of Parkinson's disease: dopaminergic pathophysiology and treatment
- (2009) K Ray Chaudhuri et al. LANCET NEUROLOGY
- Neuropathological assessment of Parkinson's disease: refining the diagnostic criteria
- (2009) Dennis W Dickson et al. LANCET NEUROLOGY
- NAADP mobilizes calcium from acidic organelles through two-pore channels
- (2009) Peter J. Calcraft et al. NATURE
- Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease
- (2009) Wataru Satake et al. NATURE GENETICS
- Genome-wide association study reveals genetic risk underlying Parkinson's disease
- (2009) Javier Simón-Sánchez et al. NATURE GENETICS
- Mutant LRRK2 R1441G BAC transgenic mice recapitulate cardinal features of Parkinson's disease
- (2009) Yanping Li et al. NATURE NEUROSCIENCE
- Lysosome biogenesis and lysosomal membrane proteins: trafficking meets function
- (2009) Paul Saftig et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Leucine-Rich Repeat Kinase 2 Regulates the Progression of Neuropathology Induced by Parkinson's-Disease-Related Mutant α-synuclein
- (2009) Xian Lin et al. NEURON
- Assembly-dependent endocytosis and clearance of extracellular a-synuclein
- (2008) He-Jin Lee et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
- (2008) Derek Narendra et al. JOURNAL OF CELL BIOLOGY
- Organization of the Pre-autophagosomal Structure Responsible for Autophagosome Formation
- (2008) Tomoko Kawamata et al. MOLECULAR BIOLOGY OF THE CELL
- Essential Role of Cyclin-G–associated Kinase (Auxilin-2) in Developing and Mature Mice
- (2008) Dong-won Lee et al. MOLECULAR BIOLOGY OF THE CELL
- Autosomal dominant dopa-responsive parkinsonism in a multigenerational Swiss family
- (2008) C. Wider et al. PARKINSONISM & RELATED DISORDERS
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More