LRRK2 regulates synaptogenesis and dopamine receptor activation through modulation of PKA activity

The genetics of Parkinson's disease: Progress and therapeutic implications

(2013) Andrew B. Singleton et al.   MOVEMENT DISORDERS

LRRK2 expression is enriched in the striosomal compartment of mouse striatum

(2012) Wim Mandemakers et al.   NEUROBIOLOGY OF DISEASE

Whole-Brain Mapping of Direct Inputs to Midbrain Dopamine Neurons

(2012) Mitsuko Watabe-Uchida et al.   NEURON

Subcellular Location of PKA Controls Striatal Plasticity: Stochastic Simulations in Spiny Dendrites

(2012) Rodrigo F. Oliveira et al.   PLoS Computational Biology

Modulation of Striatal Projection Systems by Dopamine

(2011) Charles R. Gerfen et al.   Annual Review of Neuroscience

Serotonin Induces Long-Term Depression at Corticostriatal Synapses

(2011) B. N. Mathur et al.   JOURNAL OF NEUROSCIENCE

Characterization of a selective inhibitor of the Parkinson's disease kinase LRRK2

(2011) Xianming Deng et al.   Nature Chemical Biology

How Addictive Drugs Disrupt Presynaptic Dopamine Neurotransmission

(2011) David Sulzer   NEURON

Phosphorylation-Dependent 14-3-3 Binding to LRRK2 Is Impaired by Common Mutations of Familial Parkinson's Disease

(2011) Xianting Li et al.   PLoS One

Role of Aberrant Striatal Dopamine D1 Receptor/cAMP/Protein Kinase A/DARPP32 Signaling in the Paradoxical Calming Effect of Amphetamine

(2010) F. Napolitano et al.   JOURNAL OF NEUROSCIENCE

Impaired Neurotransmitter Release in Alzheimer’s and Parkinson’s Diseases

(2010) Jie Shen   Neurodegenerative Diseases

ADF/Cofilin: a functional node in cell biology

(2010) Barbara W. Bernstein et al.   TRENDS IN CELL BIOLOGY

Dendritic spine formation and stabilization

(2009) Yoshihiro Yoshihara et al.   CURRENT OPINION IN NEUROBIOLOGY

Regulation of actin function by protein kinase A-mediated phosphorylation of Limk1

(2009) Kiran S Nadella et al.   EMBO REPORTS

Defining mechanisms of actin polymerization and depolymerization during dendritic spine morphogenesis

(2009) Pirta Hotulainen et al.   JOURNAL OF CELL BIOLOGY

Phosphorylation of Ezrin/Radixin/Moesin Proteins by LRRK2 Promotes the Rearrangement of Actin Cytoskeleton in Neuronal Morphogenesis

(2009) L. Parisiadou et al.   JOURNAL OF NEUROSCIENCE

Mutant LRRK2 R1441G BAC transgenic mice recapitulate cardinal features of Parkinson's disease

(2009) Yanping Li et al.   NATURE NEUROSCIENCE

Subcellular Dynamics of Type II PKA in Neurons

(2009) Haining Zhong et al.   NEURON

Leucine-Rich Repeat Kinase 2 Regulates the Progression of Neuropathology Induced by Parkinson's-Disease-Related Mutant α-synuclein

(2009) Xian Lin et al.   NEURON

Striatal spine plasticity in Parkinson's disease: pathological or not?

(2009) Y. Smith et al.   PARKINSONISM & RELATED DISORDERS

Stabilization of Ca2+-permeable AMPA receptors at perisynaptic sites by GluR1-S845 phosphorylation

(2009) K. He et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

R1441C mutation in LRRK2 impairs dopaminergic neurotransmission in mice

(2009) Y. Tong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ADF/Cofilin

(2008) James R. Bamburg et al.   CURRENT BIOLOGY

The Roc domain of leucine-rich repeat kinase 2 is sufficient for interaction with microtubules

(2008) Payal N. Gandhi et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Destabilization of the Postsynaptic Density by PSD-95 Serine 73 Phosphorylation Inhibits Spine Growth and Synaptic Plasticity

(2008) Pascal Steiner et al.   NEURON

Developmental regulation of leucine-rich repeat kinase 1 and 2 expression in the brain and other rodent and human organs: Implications for Parkinson’s disease

(2008) M. Westerlund et al.   NEUROSCIENCE

Structure of the ROC domain from the Parkinson's disease-associated leucine-rich repeat kinase 2 reveals a dimeric GTPase

(2008) J. Deng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Progressive behavioral deficits in DJ-1-deficient mice are associated with normal nigrostriatal function

(2007) Jayanth S. Chandran et al.   NEUROBIOLOGY OF DISEASE