Endosomal sorting and trafficking, the retromer complex and neurodegeneration
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Endosomal sorting and trafficking, the retromer complex and neurodegeneration
Authors
Keywords
-
Journal
MOLECULAR PSYCHIATRY
Volume -, Issue -, Pages -
Publisher
Springer Nature America, Inc
Online
2018-08-17
DOI
10.1038/s41380-018-0221-3
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Impaired axonal retrograde trafficking of the retromer complex augments lysosomal deficits in Alzheimer’s disease neurons
- (2017) Prasad Tammineni et al. HUMAN MOLECULAR GENETICS
- Vps35 in cooperation with LRRK2 regulates synaptic vesicle endocytosis through the endosomal pathway in Drosophila
- (2017) Tsuyoshi Inoshita et al. HUMAN MOLECULAR GENETICS
- Updated Insight into the Physiological and Pathological Roles of the Retromer Complex
- (2017) Yakubu Abubakar et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Pathways of cellular proteostasis in aging and disease
- (2017) Courtney L. Klaips et al. JOURNAL OF CELL BIOLOGY
- Rab7A regulates tau secretion
- (2017) Lilia Rodriguez et al. JOURNAL OF NEUROCHEMISTRY
- TREM2 deficiency exacerbates tau pathology through dysregulated kinase signaling in a mouse model of tauopathy
- (2017) Shane M. Bemiller et al. Molecular Neurodegeneration
- TREM2 in Neurodegenerative Diseases
- (2017) Taylor R. Jay et al. Molecular Neurodegeneration
- The retromer complex system in a transgenic mouse model of AD: influence of age
- (2017) Jin Chu et al. NEUROBIOLOGY OF AGING
- The Retromer Supports AMPA Receptor Trafficking During LTP
- (2017) Paul Temkin et al. NEURON
- TREM2 deficiency attenuates neuroinflammation and protects against neurodegeneration in a mouse model of tauopathy
- (2017) Cheryl E. G. Leyns et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Endosomal Traffic Jams Represent a Pathogenic Hub and Therapeutic Target in Alzheimer’s Disease
- (2017) Scott A. Small et al. TRENDS IN NEUROSCIENCES
- Seed-induced acceleration of amyloid-β mediated neurotoxicity in vivo
- (2017) Ramona F. Sowade et al. Nature Communications
- VPS35, the Retromer Complex and Parkinson’s Disease
- (2017) Erin T. Williams et al. Journal of Parkinsons Disease
- Parkinson Disease-linked Vps35 R524W Mutation Impairs the Endosomal Association of Retromer and Induces α-Synuclein Aggregation
- (2016) Jordan Follett et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- SNX27 and SORLA Interact to Reduce Amyloidogenic Subcellular Distribution and Processing of Amyloid Precursor Protein
- (2016) Timothy Y. Huang et al. JOURNAL OF NEUROSCIENCE
- Accumulation of amyloid-β by astrocytes result in enlarged endosomes and microvesicle-induced apoptosis of neurons
- (2016) Sofia Söllvander et al. Molecular Neurodegeneration
- TREM2 Haplodeficiency in Mice and Humans Impairs the Microglia Barrier Function Leading to Decreased Amyloid Compaction and Severe Axonal Dystrophy
- (2016) Peng Yuan et al. NEURON
- Vps35-dependent recycling of Trem2 regulates microglial function
- (2016) Jie Yin et al. TRAFFIC
- Vacuolar Protein Sorting Genes in Parkinson's Disease: A Re-appraisal of Mutations Detection Rate and Neurobiology of Disease
- (2016) Stefano Gambardella et al. Frontiers in Neuroscience
- Unexpected partial correction of metabolic and behavioral phenotypes of Alzheimer’s APP/PSEN1 mice by gene targeting of diabetes/Alzheimer’s-related Sorcs1
- (2016) Elysse M. Knight et al. Acta Neuropathologica Communications
- Coding mutations inSORL1and Alzheimer disease
- (2015) Badri N. Vardarajan et al. ANNALS OF NEUROLOGY
- Biogenesis of endosome-derived transport carriers
- (2015) Richard J. Chi et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- VPS35 in Dopamine Neurons Is Required for Endosome-to-Golgi Retrieval of Lamp2a, a Receptor of Chaperone-Mediated Autophagy That Is Critical for -Synuclein Degradation and Prevention of Pathogenesis of Parkinson's Disease
- (2015) F.-L. Tang et al. JOURNAL OF NEUROSCIENCE
- SNX15 Regulates Cell Surface Recycling of APP and Aβ Generation
- (2015) Tuancheng Feng et al. MOLECULAR NEUROBIOLOGY
- De novo deleterious genetic variations target a biological network centered on Aβ peptide in early-onset Alzheimer disease
- (2015) A Rovelet-Lecrux et al. MOLECULAR PSYCHIATRY
- SORL1 rare variants: a major risk factor for familial early-onset Alzheimer’s disease
- (2015) G Nicolas et al. MOLECULAR PSYCHIATRY
- Tau in physiology and pathology
- (2015) Yipeng Wang et al. NATURE REVIEWS NEUROSCIENCE
- Retromer in Alzheimer disease, Parkinson disease and other neurological disorders
- (2015) Scott A. Small et al. NATURE REVIEWS NEUROSCIENCE
- Cargo trafficking in Alzheimer’s disease: the possible role of retromer
- (2015) Saeed Sadigh-Eteghad et al. NEUROLOGICAL SCIENCES
- VPS35 Deficiency or Mutation Causes Dopaminergic Neuronal Loss by Impairing Mitochondrial Fusion and Function
- (2015) Fu-Lei Tang et al. Cell Reports
- Genetic variability of the retromer cargo recognition complex in parkinsonism
- (2015) Emil K. Gustavsson et al. MOVEMENT DISORDERS
- Retromer-dependent neurotransmitter receptor trafficking to synapses is altered by the Parkinson's disease VPS35 mutation p.D620N
- (2014) L. N. Munsie et al. HUMAN MOLECULAR GENETICS
- Parkinson's disease-linked mutations in VPS35 induce dopaminergic neurodegeneration
- (2014) E. Tsika et al. HUMAN MOLECULAR GENETICS
- Extracellular Monomeric Tau Protein Is Sufficient to Initiate the Spread of Tau Protein Pathology
- (2014) Claire H. Michel et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- SorLA Complement-type Repeat Domains Protect the Amyloid Precursor Protein against Processing
- (2014) Arnela Mehmedbasic et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Identification of molecular heterogeneity in SNX27-retromer-mediated endosome-to-plasma-membrane recycling
- (2014) I. J. McGough et al. JOURNAL OF CELL SCIENCE
- Vacuolar protein sorting 35 (Vps35) rescues locomotor deficits and shortened lifespan in Drosophila expressing a Parkinson’s disease mutant of Leucine-rich repeat kinase 2 (LRRK2)
- (2014) Radek Linhart et al. Molecular Neurodegeneration
- Pharmacological chaperones stabilize retromer to limit APP processing
- (2014) Vincent J Mecozzi et al. Nature Chemical Biology
- VPS35 dysfunction impairs lysosomal degradation of α-synuclein and exacerbates neurotoxicity in a Drosophila model of Parkinson's disease
- (2014) Emiko Miura et al. NEUROBIOLOGY OF DISEASE
- Hyperleucinemia causes hippocampal retromer deficiency linking diabetes to Alzheimer's disease
- (2014) Michael V. Morabito et al. NEUROBIOLOGY OF DISEASE
- Retromer Mediates a Discrete Route of Local Membrane Delivery to Dendrites
- (2014) Regina Wai-Yan Choy et al. NEURON
- The dual role of astrocyte activation and reactive gliosis
- (2014) Milos Pekny et al. NEUROSCIENCE LETTERS
- Potential pharmacological chaperones targeting cancer-associated MCL-1 and Parkinson disease-associated -synuclein
- (2014) M. Oh et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Lysosomal Sorting of Amyloid- by the SORLA Receptor Is Impaired by a Familial Alzheimer's Disease Mutation
- (2014) S. Caglayan et al. Science Translational Medicine
- TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis
- (2014) G. Kleinberger et al. Science Translational Medicine
- Endosome maturation, transport and functions
- (2014) Cameron C. Scott et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Stuck in traffic: an emerging theme in diseases of the nervous system
- (2014) Jacques Neefjes et al. TRENDS IN NEUROSCIENCES
- Retromer: A Master Conductor of Endosome Sorting
- (2014) C. Burd et al. Cold Spring Harbor Perspectives in Biology
- Mutation in VPS35 associated with Parkinson’s disease impairs WASH complex association and inhibits autophagy
- (2014) Eszter Zavodszky et al. Nature Communications
- RAB7L1 Interacts with LRRK2 to Modify Intraneuronal Protein Sorting and Parkinson’s Disease Risk
- (2013) David A. MacLeod et al. NEURON
- Microglial Beclin 1 Regulates Retromer Trafficking and Phagocytosis and Is Impaired in Alzheimer’s Disease
- (2013) Kurt M. Lucin et al. NEURON
- The Vps35 D620N Mutation Linked to Parkinson's Disease Disrupts the Cargo Sorting Function of Retromer
- (2013) Jordan Follett et al. TRAFFIC
- Endocytosis and autophagy: Shared machinery for degradation
- (2012) Christopher A. Lamb et al. BIOESSAYS
- Small Misfolded Tau Species Are Internalized via Bulk Endocytosis and Anterogradely and Retrogradely Transported in Neurons
- (2012) Jessica W. Wu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The retromer complex - endosomal protein recycling and beyond
- (2012) M. N. J. Seaman JOURNAL OF CELL SCIENCE
- Identification of Alzheimer disease-associated variants in genes that regulate retromer function
- (2012) Badri N. Vardarajan et al. NEUROBIOLOGY OF AGING
- The location and trafficking routes of the neuronal retromer and its role in amyloid precursor protein transport
- (2012) Akhil Bhalla et al. NEUROBIOLOGY OF DISEASE
- Neuronal LR11 Expression Does Not Differentiate between Clinically-Defined Alzheimer's Disease and Control Brains
- (2012) Kristen L. Sager et al. PLoS One
- A Mutation in VPS35, Encoding a Subunit of the Retromer Complex, Causes Late-Onset Parkinson Disease
- (2011) Alexander Zimprich et al. AMERICAN JOURNAL OF HUMAN GENETICS
- VPS35 Mutations in Parkinson Disease
- (2011) Carles Vilariño-Güell et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Recruitment of the endosomal WASH complex is mediated by the extended ‘tail’ of Fam21 binding to the retromer protein Vps35
- (2011) Michael E. Harbour et al. BIOCHEMICAL JOURNAL
- Endosome maturation
- (2011) Jatta Huotari et al. EMBO JOURNAL
- VPS35 haploinsufficiency increases Alzheimer’s disease neuropathology
- (2011) Lei Wen et al. JOURNAL OF CELL BIOLOGY
- A SNX3-dependent retromer pathway mediates retrograde transport of the Wnt sorting receptor Wntless and is required for Wnt secretion
- (2011) Martin Harterink et al. NATURE CELL BIOLOGY
- SNX27 mediates retromer tubule entry and endosome-to-plasma membrane trafficking of signalling receptors
- (2011) Paul Temkin et al. NATURE CELL BIOLOGY
- Retromer disruption promotes amyloidogenic APP processing
- (2011) Christopher P. Sullivan et al. NEUROBIOLOGY OF DISEASE
- Recent Advances in Retromer Biology
- (2011) Ian J. McGough et al. TRAFFIC
- Implication of mouse Vps26b–Vps29–Vps35 retromer complex in sortilin trafficking
- (2010) Ekyune Kim et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- The cargo-selective retromer complex is a recruiting hub for protein complexes that regulate endosomal tubule dynamics
- (2010) M. E. Harbour et al. JOURNAL OF CELL SCIENCE
- Diabetes-Associated SorCS1 Regulates Alzheimer's Amyloid- Metabolism: Evidence for Involvement of SorL1 and the Retromer Complex
- (2010) R. F. Lane et al. JOURNAL OF NEUROSCIENCE
- Regulation of synaptic connectivity by glia
- (2010) Cagla Eroglu et al. NATURE
- Lysosomal Dysfunction Promotes Cleavage and Neurotoxicity of Tau In Vivo
- (2010) Vikram Khurana et al. PLoS Genetics
- Astrocytes: biology and pathology
- (2009) Michael V. Sofroniew et al. ACTA NEUROPATHOLOGICA
- The Retromer Coat Complex Coordinates Endosomal Sorting and Dynein-Mediated Transport, with Carrier Recognition by the trans-Golgi Network
- (2009) Thomas Wassmer et al. DEVELOPMENTAL CELL
- Retromer
- (2008) Juan S Bonifacino et al. CURRENT OPINION IN CELL BIOLOGY
- Genomic convergence to identify candidate genes for Alzheimer Disease on chromosome 10
- (2008) Xueying Liang et al. HUMAN MUTATION
- Regulation of retromer recruitment to endosomes by sequential action of Rab5 and Rab7
- (2008) Raul Rojas et al. JOURNAL OF CELL BIOLOGY
- Retromer deficiency observed in Alzheimer's disease causes hippocampal dysfunction, neurodegeneration, and A accumulation
- (2008) A. Muhammad et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now