Pathological  -Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice

Intracerebral inoculation of pathological α-synuclein initiates a rapidly progressive neurodegenerative α-synucleinopathy in mice

(2012) Kelvin C. Luk et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The neuropathology of genetic Parkinson's disease

(2012) Markos Poulopoulos et al.   MOVEMENT DISORDERS

Propagation of Tau Pathology in a Model of Early Alzheimer's Disease

(2012) Alix de Calignon et al.   NEURON

A cytoarchitectonic and chemoarchitectonic analysis of the dopamine cell groups in the substantia nigra, ventral tegmental area, and retrorubral field in the mouse

(2011) YuHong Fu et al.   Brain Structure & Function

α-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells

(2011) Christian Hansen et al.   JOURNAL OF CLINICAL INVESTIGATION

GSPE interferes with tau aggregation in vivo: implication for treating tauopathy

(2011) Ismael Santa-Maria et al.   NEUROBIOLOGY OF AGING

Exogenous α-Synuclein Fibrils Induce Lewy Body Pathology Leading to Synaptic Dysfunction and Neuron Death

(2011) Laura A. Volpicelli-Daley et al.   NEURON

Inputs to the Dorsal Striatum of the Mouse Reflect the Parallel Circuit Architecture of the Forebrain

(2011) Weixing X. Pan et al.   Frontiers in Neuroanatomy

Sex differences in β-amyloid accumulation in 3xTg-AD mice: Role of neonatal sex steroid hormone exposure

(2010) Jenna C. Carroll et al.   BRAIN RESEARCH

Continuous and Cyclic Progesterone Differentially Interact with Estradiol in the Regulation of Alzheimer-Like Pathology in Female 3×Transgenic-Alzheimer’s Disease Mice

(2010) Jenna C. Carroll et al.   ENDOCRINOLOGY

Are synucleinopathies prion-like disorders?

(2010) Elodie Angot et al.   LANCET NEUROLOGY

Genetic Animal Models of Parkinson's Disease

(2010) Ted M. Dawson et al.   NEURON

Striatal Expression of a Calmodulin Fragment Improved Motor Function, Weight Loss, and Neuropathology in the R6/2 Mouse Model of Huntington's Disease

(2009) Y. Dai et al.   JOURNAL OF NEUROSCIENCE

Transmission and spreading of tauopathy in transgenic mouse brain

(2009) Florence Clavaguera et al.   NATURE CELL BIOLOGY

Genome-wide association study reveals genetic risk underlying Parkinson's disease

(2009) Javier Simón-Sánchez et al.   NATURE GENETICS

The Transcellular Spread of Cytosolic Amyloids, Prions, and Prionoids

(2009) Adriano Aguzzi et al.   NEURON

Inclusion formation and neuronal cell death through neuron-to-neuron transmission of  -synuclein

(2009) P. Desplats et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exogenous  -synuclein fibrils seed the formation of Lewy body-like intracellular inclusions in cultured cells

(2009) K. C. Luk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Characterization of antibodies that selectively detect α-synuclein in pathological inclusions

(2008) Elisa A. Waxman et al.   ACTA NEUROPATHOLOGICA

Selective Estrogen Receptor Modulators Differentially Regulate Alzheimer-Like Changes in Female 3xTg-AD Mice

(2008) Jenna C. Carroll et al.   ENDOCRINOLOGY

Specificity and Regulation of Casein Kinase-Mediated Phosphorylation of α-Synuclein

(2008) Elisa A. Waxman et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Transplanted dopaminergic neurons develop PD pathologic changes: A second case report

(2008) Jeffrey H. Kordower et al.   MOVEMENT DISORDERS

Lewy body–like pathology in long-term embryonic nigral transplants in Parkinson's disease

(2008) Jeffrey H Kordower et al.   NATURE MEDICINE