The road to lysosome‐related organelles: Insights from Hermansky‐Pudlak syndrome and other rare diseases
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
The road to lysosome‐related organelles: Insights from Hermansky‐Pudlak syndrome and other rare diseases
Authors
Keywords
-
Journal
TRAFFIC
Volume 20, Issue 6, Pages 404-435
Publisher
Wiley
Online
2019-04-04
DOI
10.1111/tra.12646
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Gene-edited MLE-15 Cells as a Model for the Hermansky-Pudlak Syndromes
- (2018) Seunghyi Kook et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- VPS33B and VIPAR are essential for epidermal lamellar body biogenesis and function
- (2018) Clare Rogerson et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Remodeling the Specificity of an Endosomal CORVET Tether Underlies Formation of Regulated Secretory Vesicles in the Ciliate Tetrahymena thermophila
- (2018) Daniela Sparvoli et al. CURRENT BIOLOGY
- Development of the Swimbladder Surfactant System and Biogenesis of Lysosome-Related Organelles Is Regulated by BLOS1 in Zebrafish
- (2018) Tianbing Chen et al. GENETICS
- Bombyx ortholog of the Drosophila eye color gene brown controls riboflavin transport in Malpighian tubules
- (2018) Haokun Zhang et al. INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Myosin VI and branched actin filaments mediate membrane constriction and fission of melanosomal tubule carriers
- (2018) Léa Ripoll et al. JOURNAL OF CELL BIOLOGY
- An Overview of Epidermal Lamellar Bodies: Novel roles in biological adaptations and secondary barriers
- (2018) Gopinathan K. Menon et al. JOURNAL OF DERMATOLOGICAL SCIENCE
- Biogenesis of zinc storage granules in Drosophila melanogaster
- (2018) Carlos Tejeda-Guzmán et al. JOURNAL OF EXPERIMENTAL BIOLOGY
- Galectin-3 Interacts with the CHI3L1 Axis and Contributes to Hermansky–Pudlak Syndrome Lung Disease
- (2018) Yang Zhou et al. JOURNAL OF IMMUNOLOGY
- Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B
- (2018) Morag R. Hunter et al. JOURNAL OF MOLECULAR BIOLOGY
- Hermansky-Pudlak syndrome type 2 manifests with fibrosing lung disease early in childhood
- (2018) Meike Hengst et al. Orphanet Journal of Rare Diseases
- Molecular characterization of a series of 990 index patients with albinism
- (2018) Eulalie Lasseaux et al. Pigment Cell & Melanoma Research
- Diagnostic laboratory standardization and validation of platelet transmission electron microscopy
- (2018) Dong Chen et al. PLATELETS
- Mechanism of neurotransmitter release coming into focus
- (2018) Josep Rizo PROTEIN SCIENCE
- Role of the AP-5 adaptor protein complex in late endosome-to-Golgi retrieval
- (2018) Jennifer Hirst et al. PLOS BIOLOGY
- Development of the Swimbladder Surfactant System and Biogenesis of Lysosome-Related Organelles Is Regulated by BLOS1 in Zebrafish
- (2018) Tianbing Chen et al. GENETICS
- NBEAL2 (Neurobeachin-Like 2) Is Required for Retention of Cargo Proteins by α-Granules During Their Production by Megakaryocytes
- (2018) Richard W. Lo et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- A reexamination on the deficiency of riboflavin accumulation in Malpighian tubules in larval translucent mutants of the silkworm, Bombyx mori
- (2018) Haokun Zhang et al. GENETICA
- Accumulation of uric acid in the epidermis forms the white integument of Samia ricini larvae
- (2018) Jung Lee et al. PLoS One
- A Mutation in the Borcs7 Subunit of the Lysosome Regulatory BORC Complex Results in Motor Deficits and Dystrophic Axonopathy in Mice
- (2018) John N. Snouwaert et al. Cell Reports
- Rab32-related antimicrobial pathway is involved in the progression of dextran sodium sulfate-induced colitis
- (2018) Xiaodong Xie et al. FEBS Open Bio
- Rab22A recruits BLOC‐1 and BLOC‐2 to promote the biogenesis of recycling endosomes
- (2018) Saurabh Shakya et al. EMBO REPORTS
- Function and regulation of the Caenorhabditis elegans Rab32 family member GLO-1 in lysosome-related organelle biogenesis
- (2018) Caitlin Morris et al. PLoS Genetics
- Bm-muted , orthologous to mouse muted and encoding a subunit of the BLOC-1 complex, is responsible for the otm translucent mutation of the silkworm Bombyx mori
- (2017) Haokun Zhang et al. GENE
- An actin cytoskeletal barrier inhibits lytic granule release from natural killer cells in patients with Chediak-Higashi syndrome
- (2017) Aleksandra Gil-Krzewska et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- A Ragulator–BORC interaction controls lysosome positioning in response to amino acid availability
- (2017) Jing Pu et al. JOURNAL OF CELL BIOLOGY
- LAMTOR/Ragulator is a negative regulator of Arl8b- and BORC-dependent late endosomal positioning
- (2017) Przemyslaw A. Filipek et al. JOURNAL OF CELL BIOLOGY
- The Rab7 effector PLEKHM1 binds Arl8b to promote cargo traffic to lysosomes
- (2017) Rituraj Marwaha et al. JOURNAL OF CELL BIOLOGY
- Vps33b is crucial for structural and functional hepatocyte polarity
- (2017) Joanna Hanley et al. JOURNAL OF HEPATOLOGY
- An endosomal syntaxin and the AP-3 complex are required for formation and maturation of candidate lysosome-related secretory organelles (mucocysts) in Tetrahymena thermophila
- (2017) Harsimran Kaur et al. MOLECULAR BIOLOGY OF THE CELL
- Clinical and molecular phenotyping of a child with Hermansky-Pudlak syndrome-7, an uncommon genetic type of HPS
- (2017) Melanie M. Bryan et al. MOLECULAR GENETICS AND METABOLISM
- Neurologic involvement in patients with atypical Chediak-Higashi disease
- (2017) Wendy J. Introne et al. NEUROLOGY
- Characterization of melanosomes and melanin in Japanese patients with Hermansky-Pudlak syndrome types 1, 4, 6, and 9
- (2017) Ken Okamura et al. Pigment Cell & Melanoma Research
- Clinico-molecular analysis of eleven patients with Hermansky-Pudlak type 5 syndrome, a mild form of HPS
- (2017) Vincent Michaud et al. Pigment Cell & Melanoma Research
- α-granule biogenesis: from disease to discovery
- (2017) Chang Hua Chen et al. PLATELETS
- Myosin Va’s adaptor protein melanophilin enforces track selection on the microtubule and actin networks in vitro
- (2017) Angela Oberhofer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- SM protein Munc18-2 facilitates transition of Syntaxin 11-mediated lipid mixing to complete fusion for T-lymphocyte cytotoxicity
- (2017) Waldo A. Spessott et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- BORC/kinesin-1 ensemble drives polarized transport of lysosomes into the axon
- (2017) Ginny G. Farías et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Routing of the RAB6 secretory pathway towards the lysosome related organelle of melanocytes
- (2017) Anand Patwardhan et al. Nature Communications
- Increased autophagic sequestration in adaptor protein-3 deficient dendritic cells limits inflammasome activity and impairs antibacterial immunity
- (2017) Adriana R. Mantegazza et al. PLoS Pathogens
- Impairment of dendritic cell functions in patients with adaptor protein-3 complex deficiency
- (2016) Alberto Prandini et al. BLOOD
- Mutations in AP3D1 associated with immunodeficiency and seizures define a new type of Hermansky-Pudlak syndrome
- (2016) S. Ammann et al. BLOOD
- A Bacterial Pathogen Targets a Host Rab-Family GTPase Defense Pathway with a GAP
- (2016) Stefania Spanò et al. Cell Host & Microbe
- BLOC-1 Brings Together the Actin and Microtubule Cytoskeletons to Generate Recycling Endosomes
- (2016) Cédric Delevoye et al. CURRENT BIOLOGY
- Zebrafish scarb2a insertional mutant reveals a novel function for the Scarb2/Limp2 receptor in notochord development
- (2016) Abigail Diaz-Tellez et al. DEVELOPMENTAL DYNAMICS
- ARC Syndrome-Linked Vps33B Protein Is Required for Inflammatory Endosomal Maturation and Signal Termination
- (2016) Mohammed Ali Akbar et al. IMMUNITY
- Chediak-Higashi syndrome: Lysosomal trafficking regulator domains regulate exocytosis of lytic granules but not cytokine secretion by natural killer cells
- (2016) Aleksandra Gil-Krzewska et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Impaired Lysosomal Integral Membrane Protein 2-dependent Peroxiredoxin 6 Delivery to Lamellar Bodies Accounts for Altered Alveolar Phospholipid Content in Adaptor Protein-3-deficientpearlMice
- (2016) Seunghyi Kook et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- BLOC-1 and BLOC-3 regulate VAMP7 cycling to and from melanosomes via distinct tubular transport carriers
- (2016) Megan K. Dennis et al. JOURNAL OF CELL BIOLOGY
- Lysosomal trafficking regulator Lyst links membrane trafficking to toll-like receptor–mediated inflammatory responses
- (2016) Andreas Westphal et al. JOURNAL OF EXPERIMENTAL MEDICINE
- BLOC-2 subunit HPS6 deficiency affects the tubulation and secretion of von Willebrand factor from mouse endothelial cells
- (2016) Jing Ma et al. Journal of Genetics and Genomics
- The Proteome of BLOC-1 Genetic Defects Identifies the Arp2/3 Actin Polymerization Complex to Function Downstream of the Schizophrenia Susceptibility Factor Dysbindin at the Synapse
- (2016) Avanti Gokhale et al. JOURNAL OF NEUROSCIENCE
- NLRC3 is an inhibitory sensor of PI3K–mTOR pathways in cancer
- (2016) Rajendra Karki et al. NATURE
- Rab24 interacts with the Rab7/Rab interacting lysosomal protein complex to regulate endosomal degradation
- (2016) Celina Amaya et al. TRAFFIC
- ACaenorhabditis elegansHomologue of LYST Functions in Endosome and Lysosome-Related Organelle Biogenesis
- (2016) Alec Barrett et al. TRAFFIC
- Distinct roles of the two VPS33 proteins in the endolysosomal system inCaenorhabditis elegans
- (2016) Keiko Gengyo-Ando et al. TRAFFIC
- BORC Functions Upstream of Kinesins 1 and 3 to Coordinate Regional Movement of Lysosomes along Different Microtubule Tracks
- (2016) Carlos M. Guardia et al. Cell Reports
- An Eye on Trafficking Genes: Identification of Four Eye Color Mutations in Drosophila
- (2016) P. Grant et al. G3-Genes Genomes Genetics
- A Founder Mutation in VPS11 Causes an Autosomal Recessive Leukoencephalopathy Linked to Autophagic Defects
- (2016) Jinglan Zhang et al. PLoS Genetics
- BLOS2 negatively regulates Notch signaling during neural and hematopoietic stem and progenitor cell development
- (2016) Wenwen Zhou et al. eLife
- MiniCORVET is a Vps8-containing early endosomal tether in Drosophila
- (2016) Péter Lőrincz et al. eLife
- Impairment of autophagosome-lysosome fusion in the buff mutant mice with the VPS33AD251Emutation
- (2015) Yuanli Zhen et al. Autophagy
- VPS33B regulates protein sorting into and maturation of -granule progenitor organelles in mouse megakaryocytes
- (2015) D. Bem et al. BLOOD
- Platelet geometry sensing spatially regulates -granule secretion to enable matrix self-deposition
- (2015) Y. Sakurai et al. BLOOD
- Defective PDI release from platelets and endothelial cells impairs thrombus formation in Hermansky-Pudlak syndrome
- (2015) A. Sharda et al. BLOOD
- Hemophagocytic lymphohistiocytosis caused by dominant-negative mutations in STXBP2 that inhibit SNARE-mediated membrane fusion
- (2015) W. A. Spessott et al. BLOOD
- Platelet secretion of CXCL4 is Rac1-dependent and regulates neutrophil infiltration and tissue damage in septic lung damage
- (2015) Rundk Hwaiz et al. BRITISH JOURNAL OF PHARMACOLOGY
- BORC, a Multisubunit Complex that Regulates Lysosome Positioning
- (2015) Jing Pu et al. DEVELOPMENTAL CELL
- Regulation of synaptic activity by snapin-mediated endolysosomal transport and sorting
- (2015) J. Di Giovanni et al. EMBO JOURNAL
- Neuronal copper homeostasis susceptibility by genetic defects in dysbindin, a schizophrenia susceptibility factor
- (2015) Avanti Gokhale et al. HUMAN MOLECULAR GENETICS
- Patients with Griscelli syndrome and normal pigmentation identify RAB27A mutations that selectively disrupt MUNC13-4 binding
- (2015) Valentina Cetica et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- The HabcDomain of the SNARE Vam3 Interacts with the HOPS Tethering Complex to Facilitate Vacuole Fusion
- (2015) Anna Lürick et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Axonal autophagosomes recruit dynein for retrograde transport through fusion with late endosomes
- (2015) Xiu-Tang Cheng et al. JOURNAL OF CELL BIOLOGY
- BLOC-2 targets recycling endosomal tubules to melanosomes for cargo delivery
- (2015) Megan K. Dennis et al. JOURNAL OF CELL BIOLOGY
- Impaired maturation of large dense-core vesicles in muted-deficient adrenal chromaffin cells
- (2015) Z. Hao et al. JOURNAL OF CELL SCIENCE
- The small GTPase Arl8b regulates assembly of the mammalian HOPS complex on lysosomes
- (2015) D. Khatter et al. JOURNAL OF CELL SCIENCE
- Chitinase 3–like–1 and its receptors in Hermansky-Pudlak syndrome–associated lung disease
- (2015) Yang Zhou et al. JOURNAL OF CLINICAL INVESTIGATION
- Rac1-dependent secretion of platelet-derived CCL5 regulates neutrophil recruitment via activation of alveolar macrophages in septic lung injury
- (2015) Rundk Hwaiz et al. JOURNAL OF LEUKOCYTE BIOLOGY
- The N-Ethylmaleimide-Sensitive Factor and Dysbindin Interact To Modulate Synaptic Plasticity
- (2015) A. Gokhale et al. JOURNAL OF NEUROSCIENCE
- Critical off-target effects of the widely used Rac1 inhibitors NSC23766 and EHT1864 in mouse platelets
- (2015) S. Dütting et al. JOURNAL OF THROMBOSIS AND HAEMOSTASIS
- The HOPS/class C Vps complex tethers membranes by binding to one Rab GTPase in each apposed membrane
- (2015) Ruoya Ho et al. MOLECULAR BIOLOGY OF THE CELL
- COMMD1 is linked to the WASH complex and regulates endosomal trafficking of the copper transporter ATP7A
- (2015) Christine A. Phillips-Krawczak et al. MOLECULAR BIOLOGY OF THE CELL
- Identification and clinical characterization of Hermansky-Pudlak syndrome alleles in the Pakistani population
- (2015) Sairah Yousaf et al. Pigment Cell & Melanoma Research
- A direct role for the Sec1/Munc18-family protein Vps33 as a template for SNARE assembly
- (2015) R. W. Baker et al. SCIENCE
- Vps33B is required for delivery of endocytosed cargo to lysosomes
- (2015) Romain Galmes et al. TRAFFIC
- LYST Controls the Biogenesis of the Endosomal Compartment Required for Secretory Lysosome Function
- (2015) Fernando E. Sepulveda et al. TRAFFIC
- Recruitment of VPS33A to HOPS by VPS16 Is Required for Lysosome Fusion with Endosomes and Autophagosomes
- (2015) Lena Wartosch et al. TRAFFIC
- Munc18-2 is required for Syntaxin 11 Localization on the Plasma Membrane in Cytotoxic T-Lymphocytes
- (2015) Nele M.G. Dieckmann et al. TRAFFIC
- The AP-3 adaptor complex mediates sorting of yeast and mammalian PQ-loop-family basic amino acid transporters to the vacuolar/lysosomal membrane
- (2015) Elisa Llinares et al. Scientific Reports
- A Two-Tier Golgi-Based Control of Organelle Size Underpins the Functional Plasticity of Endothelial Cells
- (2014) Francesco Ferraro et al. DEVELOPMENTAL CELL
- Biogenesis of Lysosome-related Organelles Complex-1 Subunit 1 (BLOS1) Interacts with Sorting Nexin 2 and the Endosomal Sorting Complex Required for Transport-I (ESCRT-I) Component TSG101 to Mediate the Sorting of Epidermal Growth Factor Receptor into Endosomal Compartments
- (2014) Aili Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Myosin Vc Interacts with Rab32 and Rab38 Proteins and Works in the Biogenesis and Secretion of Melanosomes
- (2014) Jarred J. Bultema et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- HPS6 interacts with dynactin p150Glued to mediate retrograde trafficking and maturation of lysosomes
- (2014) K. Li et al. JOURNAL OF CELL SCIENCE
- Dictyostelium LvsB has a regulatory role in endosomal vesicle fusion
- (2014) Kristin Falkenstein et al. JOURNAL OF CELL SCIENCE
- Caenorhabditis elegans HOPS and CCZ-1 mediate trafficking to lysosome-related organelles independently of RAB-7 and SAND-1
- (2014) Jared L. Delahaye et al. MOLECULAR BIOLOGY OF THE CELL
- The HOPS complex mediates autophagosome–lysosome fusion through interaction with syntaxin 17
- (2014) Peidu Jiang et al. MOLECULAR BIOLOGY OF THE CELL
- Interaction of the HOPS complex with Syntaxin 17 mediates autophagosome clearance in Drosophila
- (2014) Szabolcs Takáts et al. MOLECULAR BIOLOGY OF THE CELL
- Mutation of NLRC4 causes a syndrome of enterocolitis and autoinflammation
- (2014) Neil Romberg et al. NATURE GENETICS
- Platelet mechanosensing of substrate stiffness during clot formation mediates adhesion, spreading, and activation
- (2014) Yongzhi Qiu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- LYST Affects Lysosome Size and Quantity, but not Trafficking or Degradation Through Autophagy or Endocytosis
- (2014) Petter Holland et al. TRAFFIC
- Damage control: cellular mechanisms of plasma membrane repair
- (2014) Norma W. Andrews et al. TRENDS IN CELL BIOLOGY
- The Biogenesis of Lysosomes and Lysosome-Related Organelles
- (2014) J. P. Luzio et al. Cold Spring Harbor Perspectives in Biology
- Vesicles derived via AP-3-dependent recycling contribute to asynchronous release and influence information transfer
- (2014) Alesya Evstratova et al. Nature Communications
- Recycling Endosome Tubule Morphogenesis from Sorting Endosomes Requires the Kinesin Motor KIF13A
- (2014) Cédric Delevoye et al. Cell Reports
- An intracellular anion channel critical for pigmentation
- (2014) Nicholas W Bellono et al. eLife
- SM proteins Sly1 and Vps33 co-assemble with Sec17 and SNARE complexes to oppose SNARE disassembly by Sec18
- (2014) Braden T Lobingier et al. eLife
- Abnormal megakaryocyte development and platelet function in Nbeal2-/- mice
- (2013) W. H. A. Kahr et al. BLOOD
- Lysosome-related organelles: unusual compartments become mainstream
- (2013) Michael S Marks et al. CURRENT OPINION IN CELL BIOLOGY
- Syntaxin11 serves as a t-SNARE for the fusion of lytic granules in human cytotoxic T lymphocytes
- (2013) Mahantappa Halimani et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- snow white, a Zebrafish Model of Hermansky-Pudlak Syndrome Type 5
- (2013) C. M. S. Daly et al. GENETICS
- Structural Basis for the Recognition of Tyrosine-based Sorting Signals by the μ3A Subunit of the AP-3 Adaptor Complex
- (2013) Gonzalo A. Mardones et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Functions of Class V Myosins in Neurons
- (2013) John A. Hammer et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The BLOC-1 complex promotes endosomal maturation by recruiting the Rab5 GTPase-activating protein Msb3
- (2013) Arun T. John Peter et al. JOURNAL OF CELL BIOLOGY
- Notochord vacuoles are lysosome-related organelles that function in axis and spine morphogenesis
- (2013) Kathryn Ellis et al. JOURNAL OF CELL BIOLOGY
- Lysosomal sorting receptors are essential for secretory granule biogenesis inTetrahymena
- (2013) Joseph S. Briguglio et al. JOURNAL OF CELL BIOLOGY
- Autophagosomal Syntaxin17-dependent lysosomal degradation maintains neuronal function inDrosophila
- (2013) Szabolcs Takáts et al. JOURNAL OF CELL BIOLOGY
- Gray platelet syndrome and defective thrombo-inflammation in Nbeal2-deficient mice
- (2013) Carsten Deppermann et al. JOURNAL OF CLINICAL INVESTIGATION
- Chemical-genetic disruption of clathrin function spares adaptor complex 3–dependent endosome vesicle biogenesis
- (2013) Stephanie A. Zlatic et al. MOLECULAR BIOLOGY OF THE CELL
- The WASH complex, an endosomal Arp2/3 activator, interacts with the Hermansky–Pudlak syndrome complex BLOC-1 and its cargo phosphatidylinositol-4-kinase type IIα
- (2013) P. V. Ryder et al. MOLECULAR BIOLOGY OF THE CELL
- Hermansky-Pudlak Syndrome: Health Care Throughout Life
- (2013) S. L. Seward et al. PEDIATRICS
- Crystal Structures of the Sec1/Munc18 (SM) Protein Vps33, Alone and Bound to the Homotypic Fusion and Vacuolar Protein Sorting (HOPS) Subunit Vps16*
- (2013) Richard W. Baker et al. PLoS One
- Syntaxin binding mechanism and disease-causing mutations in Munc18-2
- (2013) Y. Hackmann et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structural basis of Vps33A recruitment to the human HOPS complex by Vps16
- (2013) S. C. Graham et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Microsatellite markers as a rapid approach for autozygosity mapping in Hermansky-Pudlak syndrome: Identification of the second HPS7 mutation in a patient presenting late in life
- (2013) Gillian C. Lowe et al. THROMBOSIS AND HAEMOSTASIS
- Antagonistic Control of Lysosomal Fusion by Rab14 and the Lyst-Related Protein LvsB
- (2013) Elena Kypri et al. TRAFFIC
- The BEACH Is Hot: A LYST of Emerging Roles for BEACH-Domain Containing Proteins in Human Disease
- (2013) Andrew R. Cullinane et al. TRAFFIC
- hVps41 and VAMP7 function in direct TGN to late endosome transport of lysosomal membrane proteins
- (2013) Maaike S. Pols et al. Nature Communications
- Widespread Dysregulation of Peptide Hormone Release in Mice Lacking Adaptor Protein AP-3
- (2013) Daniel W. Sirkis et al. PLoS Genetics
- The Alveolar Epithelium Determines Susceptibility to Lung Fibrosis in Hermansky-Pudlak Syndrome
- (2012) Lisa R. Young et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Terminal transport of lytic granules to the immune synapse is mediated by the kinesin-1/Slp3/Rab27a complex
- (2012) M. Kurowska et al. BLOOD
- Mechanism of platelet dense granule biogenesis: study of cargo transport and function of Rab32 and Rab38 in a model system
- (2012) A. L. Ambrosio et al. BLOOD
- Munc18b/STXBP2 is required for platelet secretion
- (2012) R. Al Hawas et al. BLOOD
- Syntaxin-11, but not syntaxin-2 or syntaxin-4, is required for platelet secretion
- (2012) S. Ye et al. BLOOD
- Exome sequencing reveals a pallidin mutation in a Hermansky-Pudlak-like primary immunodeficiency syndrome
- (2012) R. Badolato et al. BLOOD
- The VPS33B-binding protein VPS16B is required in megakaryocyte and platelet -granule biogenesis
- (2012) D. Urban et al. BLOOD
- BLOC-3 Mutated in Hermansky-Pudlak Syndrome Is a Rab32/38 Guanine Nucleotide Exchange Factor
- (2012) Andreas Gerondopoulos et al. CURRENT BIOLOGY
- Type II phosphatidylinositol 4-kinase regulates trafficking of secretory granule proteins in Drosophila
- (2012) J. Burgess et al. DEVELOPMENT
- A homolog of the human Hermansky–Pudluck syndrome-5 (HPS5) gene is responsible for the oa larval translucent mutants in the silkworm, Bombyx mori
- (2012) T. Fujii et al. GENETICA
- Reduced expression of the dysbindin-like gene in the Bombyx mori ov mutant exhibiting mottled translucency of the larval skin
- (2012) Lingyan Wang et al. GENOME
- Correlation between platelet phenotype and NBEAL2 genotype in patients with congenital thrombocytopenia and -granule deficiency
- (2012) R. Bottega et al. HAEMATOLOGICA
- Associations among genotype, clinical phenotype, and intracellular localization of trafficking proteins in ARC syndrome
- (2012) Holly Smith et al. HUMAN MUTATION
- Adaptor Protein-3 in Dendritic Cells Facilitates Phagosomal Toll-like Receptor Signaling and Antigen Presentation to CD4+ T Cells
- (2012) Adriana R. Mantegazza et al. IMMUNITY
- BLOC-2, AP-3, and AP-1 Proteins Function in Concert with Rab38 and Rab32 Proteins to Mediate Protein Trafficking to Lysosome-related Organelles
- (2012) Jarred J. Bultema et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Differential recognition of a dileucine-based sorting signal by AP-1 and AP-3 reveals a requirement for both BLOC-1 and AP-3 in delivery of OCA2 to melanosomes
- (2012) Anand Sitaram et al. MOLECULAR BIOLOGY OF THE CELL
- Sec1/Munc18 protein Vps33 binds to SNARE domains and the quaternary SNARE complex
- (2012) Braden T. Lobingier et al. MOLECULAR BIOLOGY OF THE CELL
- Unknown
- (2012) Bernadette Gochuico et al. MOLECULAR MEDICINE
- Amniotic lamellar body count and congenital diaphragmatic hernia in humans and in a rat model
- (2012) Yuriko Watanabe et al. PEDIATRIC RESEARCH
- Hermansky-Pudlak syndrome: pigmentary and non-pigmentary defects and their pathogenesis
- (2012) Ai-Hua Wei et al. Pigment Cell & Melanoma Research
- A BLOC-1 mutation screen reveals a novel BLOC1S3 mutation in Hermansky-Pudlak Syndrome type 8
- (2012) Andrew R. Cullinane et al. Pigment Cell & Melanoma Research
- Rab32 Is Important for Autophagy and Lipid Storage in Drosophila
- (2012) Chao Wang et al. PLoS One
- C. elegans BLOC-1 Functions in Trafficking to Lysosome-Related Gut Granules
- (2012) Greg J. Hermann et al. PLoS One
- Molecular architecture of the multisubunit homotypic fusion and vacuole protein sorting (HOPS) tethering complex
- (2012) C. Brocker et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Rab32-Dependent Pathway Contributes to Salmonella Typhi Host Restriction
- (2012) S. Spano et al. SCIENCE
- The BLOS1-Interacting Protein KXD1 is Involved in the Biogenesis of Lysosome-Related Organelles
- (2012) Qing Yang et al. TRAFFIC
- Drosophila mauveMutants Reveal a Role of LYST Homologs Late in the Maturation of Phagosomes and Autophagosomes
- (2012) Mokhlasur Rahman et al. TRAFFIC
- Snapin Recruits Dynein to BDNF-TrkB Signaling Endosomes for Retrograde Axonal Transport and Is Essential for Dendrite Growth of Cortical Neurons
- (2012) Bing Zhou et al. Cell Reports
- Rab38 targets to lamellar bodies and normalizes their sizes in lung alveolar type II epithelial cells
- (2011) Linghui Zhang et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Early Alveolar Epithelial Dysfunction Promotes Lung Inflammation in a Mouse Model of Hermansky-Pudlak Syndrome
- (2011) Elena N. Atochina-Vasserman et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Dysbindin-Containing Complexes and their Proposed Functions in Brain: From Zero to (too) Many in a Decade
- (2011) Cristina A Ghiani et al. ASN Neuro
- The munc13-4-rab27 complex is specifically required for tethering secretory lysosomes at the plasma membrane
- (2011) E. D. Elstak et al. BLOOD
- Autophagosome Precursor Maturation Requires Homotypic Fusion
- (2011) Kevin Moreau et al. CELL
- Endosome maturation
- (2011) Jatta Huotari et al. EMBO JOURNAL
- Assembly and Architecture of Biogenesis of Lysosome-related Organelles Complex-1 (BLOC-1)
- (2011) Hyung Ho Lee et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Actin polymerization driven by WASH causes V-ATPase retrieval and vesicle neutralization before exocytosis
- (2011) Michael Carnell et al. JOURNAL OF CELL BIOLOGY
- Thefull-of-bacteriagene is required for phagosome maturation during immune defense inDrosophila
- (2011) Mohammed Ali Akbar et al. JOURNAL OF CELL BIOLOGY
- AP-1 and clathrin are essential for secretory granule biogenesis in Drosophila
- (2011) Jason Burgess et al. MOLECULAR BIOLOGY OF THE CELL
- The schizophrenia susceptibility factor dysbindin and its associated complex sort cargoes from cell bodies to the synapse
- (2011) Jennifer Larimore et al. MOLECULAR BIOLOGY OF THE CELL
- HOPS drives vacuole fusion by binding the vacuolar SNARE complex and the Vam7 PX domain via two distinct sites
- (2011) Lukas Krämer et al. MOLECULAR BIOLOGY OF THE CELL
- Mutations in NBEAL2, encoding a BEACH protein, cause gray platelet syndrome
- (2011) Walter HA Kahr et al. NATURE GENETICS
- Exome sequencing identifies NBEAL2 as the causative gene for gray platelet syndrome
- (2011) Cornelis A Albers et al. NATURE GENETICS
- NBEAL2 is mutated in gray platelet syndrome and is required for biogenesis of platelet α-granules
- (2011) Meral Gunay-Aygun et al. NATURE GENETICS
- Rab GTPases Regulating Phagosome Maturation Are Differentially Recruited to Mycobacterial Phagosomes
- (2011) Shintaro Seto et al. TRAFFIC
- The Enlarged Lysosomes in beigej Cells Result From Decreased Lysosome Fission and Not Increased Lysosome Fusion
- (2011) Nina Durchfort et al. TRAFFIC
- The Fifth Adaptor Protein Complex
- (2011) Jennifer Hirst et al. PLOS BIOLOGY
- Tethering Factors as Organizers of Intracellular Vesicular Traffic
- (2010) I-Mei Yu et al. Annual Review of Cell and Developmental Biology
- Munc13-4 is a limiting factor in the pathway required for platelet granule release and hemostasis
- (2010) Q. Ren et al. BLOOD
- The platelet interior revisited: electron tomography reveals tubular -granule subtypes
- (2010) H. van Nispen tot Pannerden et al. BLOOD
- Transgenic analysis of the BmBLOS2 gene that governs the translucency of the larval integument of the silkworm, Bombyx mori
- (2010) T. Fujii et al. INSECT MOLECULAR BIOLOGY
- Conservation and Diversification of Dileucine Signal Recognition by Adaptor Protein (AP) Complex Variants
- (2010) Rafael Mattera et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structure-Function Analysis of VPS9-Ankyrin-repeat Protein (Varp) in the Trafficking of Tyrosinase-related Protein 1 in Melanocytes
- (2010) Kanako Tamura et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- RNAi screen identifies a role for adaptor protein AP-3 in sorting to the regulated secretory pathway
- (2010) Cédric S. Asensio et al. JOURNAL OF CELL BIOLOGY
- Hermansky-Pudlak Protein Complexes, AP-3 and BLOC-1, Differentially Regulate Presynaptic Composition in the Striatum and Hippocampus
- (2010) K. Newell-Litwa et al. JOURNAL OF NEUROSCIENCE
- The ERM proteins interact with the HOPS complex to regulate the maturation of endosomes
- (2010) Dafne Chirivino et al. MOLECULAR BIOLOGY OF THE CELL
- Mutations in VIPAR cause an arthrogryposis, renal dysfunction and cholestasis syndrome phenotype with defects in epithelial polarization
- (2010) Andrew R Cullinane et al. NATURE GENETICS
- The SM protein Vps33 and the t-SNARE Habc domain promote fusion pore opening
- (2010) Michel Pieren et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Snapin-Regulated Late Endosomal Transport Is Critical for Efficient Autophagy-Lysosomal Function in Neurons
- (2010) Qian Cai et al. NEURON
- Novel mutation causing Hermansky-Pudlak Syndrome Type 2
- (2010) Pei-Wen Chiang et al. PEDIATRIC BLOOD & CANCER
- Functional interactions between OCA2 and the protein complexes BLOC-1, BLOC-2, and AP-3 inferred from epistatic analyses of mouse coat pigmentation
- (2010) Diego J. Hoyle et al. Pigment Cell & Melanoma Research
- Slc15a4, AP-3, and Hermansky-Pudlak syndrome proteins are required for Toll-like receptor signaling in plasmacytoid dendritic cells
- (2010) A. L. Blasius et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Bifurcation of Toll-Like Receptor 9 Signaling by Adaptor Protein 3
- (2010) M. Sasai et al. SCIENCE
- Defined Subunit Arrangement and Rab Interactions Are Required for Functionality of the HOPS Tethering Complex
- (2010) Clemens W. Ostrowicz et al. TRAFFIC
- Early Origin of Genes Encoding Subunits of Biogenesis of Lysosome-related Organelles Complex-1, -2 and -3
- (2010) Verónica T. Cheli et al. TRAFFIC
- Yeast Homologues of Three BLOC-1 Subunits Highlight KxDL Proteins As Conserved Interactors of BLOC-1
- (2010) Matthew J. Hayes et al. TRAFFIC
- Familial Hemophagocytic Lymphohistiocytosis Type 5 (FHL-5) Is Caused by Mutations in Munc18-2 and Impaired Binding to Syntaxin 11
- (2009) Udo zur Stadt et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Altered lung surfactant system in a Rab38-deficient rat model of Hermansky-Pudlak syndrome
- (2009) Kazuhiro Osanai et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- TI-VAMP/VAMP7 and VAMP3/cellubrevin: two v-SNARE proteins involved in specific steps of the autophagy/multivesicular body pathways
- (2009) Claudio Marcelo Fader et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- A concanavalin A-like lectin domain in the CHS1/LYST protein, shared by members of the BEACH family
- (2009) Agathe Burgess et al. BIOINFORMATICS
- AP-3-dependent trafficking and disease: the first decade
- (2009) Esteban C Dell’Angelica CURRENT OPINION IN CELL BIOLOGY
- Neutrophil elastase–processing defect in cyclic hematopoietic dogs
- (2009) Ronghua Meng et al. EXPERIMENTAL HEMATOLOGY
- Two patients with Hermansky Pudlak syndrome type 2 and novel mutations in AP3B1
- (2009) M. Wenham et al. HAEMATOLOGICA
- Genetic modifiers of abnormal organelle biogenesis in a Drosophila model of BLOC-1 deficiency
- (2009) Verónica T. Cheli et al. HUMAN MOLECULAR GENETICS
- AP-1 and KIF13A coordinate endosomal sorting and positioning during melanosome biogenesis
- (2009) Cédric Delevoye et al. JOURNAL OF CELL BIOLOGY
- Munc18-2 deficiency causes familial hemophagocytic lymphohistiocytosis type 5 and impairs cytotoxic granule exocytosis in patient NK cells
- (2009) Marjorie Côte et al. JOURNAL OF CLINICAL INVESTIGATION
- Clinical and cellular characterisation of Hermansky-Pudlak syndrome type 6
- (2009) M Huizing et al. JOURNAL OF MEDICAL GENETICS
- Clinical Characteristics and VPS33B Mutations in Patients With ARC Syndrome
- (2009) Joo Young Jang et al. JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION
- Roles of BLOC-1 and Adaptor Protein-3 Complexes in Cargo Sorting to Synaptic Vesicles
- (2009) Karen Newell-Litwa et al. MOLECULAR BIOLOGY OF THE CELL
- The SM Protein Car/Vps33A Regulates SNARE-mediated Trafficking to Lysosomes and Lysosome-related Organelles
- (2009) Mohammed A. Akbar et al. MOLECULAR BIOLOGY OF THE CELL
- Varp Is a Novel Rab32/38-binding Protein That Regulates Tyrp1 Trafficking in Melanocytes
- (2009) Kanako Tamura et al. MOLECULAR BIOLOGY OF THE CELL
- The dysbindin-containing complex (BLOC-1) in brain: developmental regulation, interaction with SNARE proteins and role in neurite outgrowth
- (2009) C A Ghiani et al. MOLECULAR PSYCHIATRY
- New roles for endosomes: from vesicular carriers to multi-purpose platforms
- (2009) Gwyn W. Gould et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Griscelli syndrome: a model system to study vesicular trafficking
- (2009) Mireille Van Gele et al. Pigment Cell & Melanoma Research
- Involvement of Vps33a in the Fusion of Uroplakin-Degrading Multivesicular Bodies with Lysosomes
- (2009) Xuemei Guo et al. TRAFFIC
- A Mutation in Rab38 Small GTPase Causes Abnormal Lung Surfactant Homeostasis and Aberrant Alveolar Structure in Mice
- (2008) Kazuhiro Osanai et al. AMERICAN JOURNAL OF PATHOLOGY
- Defective Lamellar Granule Secretion in Arthrogryposis, Renal Dysfunction, and Cholestasis Syndrome Caused by a Mutation in VPS33B
- (2008) Dov Hershkovitz et al. ARCHIVES OF DERMATOLOGY
- A newly identified isoform of Slp2a associates with Rab27a in cytotoxic T cells and participates to cytotoxic granule secretion
- (2008) G. Menasche et al. BLOOD
- Subcellular localization of ammonium transporters in Dictyostelium discoideum
- (2008) Janet H Kirsten et al. BMC CELL BIOLOGY
- Sorting of the v-SNARE VAMP7 in Dictyostelium discoideum: A role for more than one Adaptor Protein (AP) complex
- (2008) Nelly Bennett et al. EXPERIMENTAL CELL RESEARCH
- Molecular investigations to improve diagnostic accuracy in patients with ARC syndrome
- (2008) Andrew R. Cullinane et al. HUMAN MUTATION
- DTNBP1, a schizophrenia susceptibility gene, affects kinetics of transmitter release
- (2008) Xiao-Wei Chen et al. JOURNAL OF CELL BIOLOGY
- The role of Rab38 in platelet dense granule defects
- (2008) I. NINKOVIC et al. JOURNAL OF THROMBOSIS AND HAEMOSTASIS
- Protein Networks Supporting AP-3 Function in Targeting Lysosomal Membrane Proteins
- (2008) Thorsten Baust et al. MOLECULAR BIOLOGY OF THE CELL
- HOPS Proofreads the trans-SNARE Complex for Yeast Vacuole Fusion
- (2008) Vincent J. Starai et al. MOLECULAR BIOLOGY OF THE CELL
- Genome-wide Analysis of AP-3–dependent Protein Transport in Yeast
- (2008) Vikram C. Anand et al. MOLECULAR BIOLOGY OF THE CELL
- Cell-specific ATP7A transport sustains copper-dependent tyrosinase activity in melanosomes
- (2008) Subba Rao Gangi Setty et al. NATURE
- A structural explanation for the binding of endocytic dileucine motifs by the AP2 complex
- (2008) Bernard T. Kelly et al. NATURE
- Iris phenotypes and pigment dispersion caused by genes influencing pigmentation
- (2008) Michael G. Anderson et al. Pigment Cell & Melanoma Research
- Electron tomography of early melanosomes: Implications for melanogenesis and the generation of fibrillar amyloid sheets
- (2008) I. Hurbain et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Slp1 and Slp2-a Localize to the Plasma Membrane of CTL and Contribute to Secretion from the Immunological Synapse
- (2008) Oliver Holt et al. TRAFFIC
- Altered Composition and Secretion of Lysosome-Derived Compartments in Dictyostelium AP-3 Mutant Cells
- (2008) Steve J. Charette et al. TRAFFIC
- Dysbindin (DTNBP1) and the Biogenesis of Lysosome-Related Organelles Complex 1 (BLOC-1): Main and Epistatic Gene Effects Are Potential Contributors to Schizophrenia Susceptibility
- (2007) Derek W. Morris et al. BIOLOGICAL PSYCHIATRY
- Formation and function of Weibel-Palade bodies
- (2007) D. J. Metcalf et al. JOURNAL OF CELL SCIENCE
- A new look at Weibel–Palade body structure in endothelial cells using electron tomography
- (2007) K.M. Valentijn et al. JOURNAL OF STRUCTURAL BIOLOGY
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started