The schizophrenia susceptibility factor dysbindin and its associated complex sort cargoes from cell bodies to the synapse

Mechanisms of polarized membrane trafficking in neurons — Focusing in on endosomes

(2011) Zofia M. Lasiecka et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Cell Biology of the BLOC-1 Complex Subunit Dysbindin, a Schizophrenia Susceptibility Gene

(2011) Ariana P. Mullin et al.   MOLECULAR NEUROBIOLOGY

Protein scaffolds in the coupling of synaptic exocytosis and endocytosis

(2011) Volker Haucke et al.   NATURE REVIEWS NEUROSCIENCE

Synaptic Dysbindin-1 Reductions in Schizophrenia Occur in an Isoform-Specific Manner Indicating Their Subsynaptic Location

(2011) Konrad Talbot et al.   PLoS One

Endocytosis and Endosomes at the Crossroads of Regulating Trafficking of Axon Outgrowth-Modifying Receptors

(2011) Bettina Winckler et al.   TRAFFIC

Sorting of the Alzheimer's Disease Amyloid Precursor Protein Mediated by the AP-4 Complex

(2010) Patricia V. Burgos et al.   DEVELOPMENTAL CELL

AP-1/σ1B-adaptin mediates endosomal synaptic vesicle recycling, learning and memory

(2010) Nataliya Glyvuk et al.   EMBO JOURNAL

Adaptor protein complex-4 (AP-4) deficiency causes a novel autosomal recessive cerebral palsy syndrome with microcephaly and intellectual disability

(2010) A. Moreno-De-Luca et al.   JOURNAL OF MEDICAL GENETICS

Hermansky-Pudlak Protein Complexes, AP-3 and BLOC-1, Differentially Regulate Presynaptic Composition in the Striatum and Hippocampus

(2010) K. Newell-Litwa et al.   JOURNAL OF NEUROSCIENCE

Dysbindin-1, WAVE2 and Abi-1 form a complex that regulates dendritic spine formation

(2010) H Ito et al.   MOLECULAR PSYCHIATRY

22q11.2 microdeletions: linking DNA structural variation to brain dysfunction and schizophrenia

(2010) Maria Karayiorgou et al.   NATURE REVIEWS NEUROSCIENCE

Dysbindin Promotes the Post-Endocytic Sorting of G Protein-Coupled Receptors to Lysosomes

(2010) Aaron Marley et al.   PLoS One

AP-3-dependent trafficking and disease: the first decade

(2009) Esteban C Dell’Angelica   CURRENT OPINION IN CELL BIOLOGY

Neurobehavioral abnormalities in the dysbindin-1 mutant, sandy, on a C57BL/6J genetic background

(2009) M. M. Cox et al.   GENES BRAIN AND BEHAVIOR

Genetic modifiers of abnormal organelle biogenesis in a Drosophila model of BLOC-1 deficiency

(2009) Verónica T. Cheli et al.   HUMAN MOLECULAR GENETICS

Dysbindin-1 in dorsolateral prefrontal cortex of schizophrenia cases is reduced in an isoform-specific manner unrelated to dysbindin-1 mRNA expression

(2009) J. Tang et al.   HUMAN MOLECULAR GENETICS

Palmitoylation Controls the Catalytic Activity and Subcellular Distribution of Phosphatidylinositol 4-Kinase IIα

(2009) Barbara Barylko et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Roles of BLOC-1 and Adaptor Protein-3 Complexes in Cargo Sorting to Synaptic Vesicles

(2009) Karen Newell-Litwa et al.   MOLECULAR BIOLOGY OF THE CELL

The dysbindin-containing complex (BLOC-1) in brain: developmental regulation, interaction with SNARE proteins and role in neurite outgrowth

(2009) C A Ghiani et al.   MOLECULAR PSYCHIATRY

Snapin Facilitates the Synchronization of Synaptic Vesicle Fusion

(2009) Ping-Yue Pan et al.   NEURON

Polarized sorting of AMPA receptors to the somatodendritic domain is regulated by adaptor protein AP-4

(2009) Shinji Matsuda et al.   NEUROSCIENCE RESEARCH

Dysbindin regulates hippocampal LTP by controlling NMDA receptor surface expression

(2009) Tina Tze-Tsang Tang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of dysbindin in dopamine receptor trafficking and cortical GABA function

(2009) Y. Ji et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Schizophrenia Susceptibility Gene dysbindin Controls Synaptic Homeostasis

(2009) D. K. Dickman et al.   SCIENCE

Schizophrenia: The "BLOC" May Be in the Endosomes

(2009) P. V. Ryder et al.   Science Signaling

Candidate genes for schizophrenia: A survey of association studies and gene ranking

(2008) Jingchun Sun et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Behavioral characterization of dysbindin-1 deficient sandy mice

(2008) Sanjeev K. Bhardwaj et al.   BEHAVIOURAL BRAIN RESEARCH

Behavioral abnormalities and dopamine reductions in sdy mutant mice with a deletion in Dtnbp1, a susceptibility gene for schizophrenia

(2008) Satoko Hattori et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Clinical, cellular, and neuropathological consequences ofAP1S2mutations: further delineation of a recognizable X-linked mental retardation syndrome

(2008) Guntram Borck et al.   HUMAN MUTATION

Hermansky-Pudlak Syndrome Protein Complexes Associate with Phosphatidylinositol 4-Kinase Type II α in Neuronal and Non-neuronal Cells

(2008) Gloria Salazar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

DTNBP1, a schizophrenia susceptibility gene, affects kinetics of transmitter release

(2008) Xiao-Wei Chen et al.   JOURNAL OF CELL BIOLOGY

Phosphatidylinositol-4-Kinase Type II Alpha Contains an AP-3–sorting Motif and a Kinase Domain That Are Both Required for Endosome Traffic

(2008) Branch Craige et al.   MOLECULAR BIOLOGY OF THE CELL

Clathrin is a key regulator of basolateral polarity

(2008) Sylvie Deborde et al.   NATURE

Cell-specific ATP7A transport sustains copper-dependent tyrosinase activity in melanosomes

(2008) Subba Rao Gangi Setty et al.   NATURE

Systematic meta-analyses and field synopsis of genetic association studies in schizophrenia: the SzGene database

(2008) Nicole C Allen et al.   NATURE GENETICS

Accumulation of AMPA Receptors in Autophagosomes in Neuronal Axons Lacking Adaptor Protein AP-4

(2008) Shinji Matsuda et al.   NEURON

Disruption of AP1S1, Causing a Novel Neurocutaneous Syndrome, Perturbs Development of the Skin and Spinal Cord

(2008) Alexandre Montpetit et al.   PLoS Genetics