Neuronal copper homeostasis susceptibility by genetic defects in dysbindin, a schizophrenia susceptibility factor

Redox dysregulation, neuroinflammation, and NMDA receptor hypofunction: A “central hub” in schizophrenia pathophysiology?

(2016) P. Steullet et al.   SCHIZOPHRENIA RESEARCH

Gene Dosage in the Dysbindin Schizophrenia Susceptibility Network Differentially Affect Synaptic Function and Plasticity

(2015) A. P. Mullin et al.   JOURNAL OF NEUROSCIENCE

COMMD1 is linked to the WASH complex and regulates endosomal trafficking of the copper transporter ATP7A

(2015) Christine A. Phillips-Krawczak et al.   MOLECULAR BIOLOGY OF THE CELL

Molecular basis of neurodegeneration and neurodevelopmental defects in Menkes disease

(2015) Stephanie Zlatic et al.   NEUROBIOLOGY OF DISEASE

Mutations in the BLOC-1 Subunits Dysbindin and Muted Generate Divergent and Dosage-dependent Phenotypes

(2014) Jennifer Larimore et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Schizophrenia Susceptibility GeneDysbindinRegulates Dendritic Spine Dynamics

(2014) Jie-Min Jia et al.   JOURNAL OF NEUROSCIENCE

Copper overload and deficiency both adversely affect the central nervous system of Drosophila

(2014) Joab E. C. Hwang et al.   Metallomics

Juvenile Antioxidant Treatment Prevents Adult Deficits in a Developmental Model of Schizophrenia

(2014) Jan-Harry Cabungcal et al.   NEURON

Impaired Metabolic Reactivity to Oxidative Stress in Early Psychosis Patients

(2014) Margot Fournier et al.   SCHIZOPHRENIA BULLETIN

Gene–Environment Interactions in Severe Mental Illness

(2014) Rudolf Uher   Frontiers in Psychiatry

Copper chaperone Atox1 interacts with the metal-binding domain of Wilson's disease protein in cisplatin detoxification

(2013) Nataliya V. Dolgova et al.   BIOCHEMICAL JOURNAL

MEDNIK syndrome: a novel defect of copper metabolism treatable by zinc acetate therapy

(2013) Diego Martinelli et al.   BRAIN

Psychiatric aspects of Wilson disease: a review

(2013) Paula C. Zimbrean et al.   GENERAL HOSPITAL PSYCHIATRY

Psychotic Symptoms After Combined Metronidazole-Disulfiram Use

(2013) Jurjen J. Luykx et al.   JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY

Peptidylglycine α-amidating monooxygenase heterozygosity alters brain copper handling with region specificity

(2013) Eric D. Gaier et al.   JOURNAL OF NEUROCHEMISTRY

The WASH complex, an endosomal Arp2/3 activator, interacts with the Hermansky–Pudlak syndrome complex BLOC-1 and its cargo phosphatidylinositol-4-kinase type IIα

(2013) P. V. Ryder et al.   MOLECULAR BIOLOGY OF THE CELL

Transcriptional remodelling in response to changing copper levels in the Wilson and Menkes disease model of Saccharomyces cerevisiae

(2013) Ayca Cankorur-Cetinkaya et al.   Molecular BioSystems

Cuprizone short-term exposure: Astrocytic IL-6 activation and behavioral changes relevant to psychosis

(2013) Tomoaki Tezuka et al.   NEUROBIOLOGY OF DISEASE

Determinants for Simultaneous Binding of Copper and Platinum to Human Chaperone Atox1: Hitchhiking not Hijacking

(2013) Maria E. Palm-Espling et al.   PLoS One

Cognitive and motivational deficits together with prefrontal oxidative stress in a mouse model for neuropsychiatric illness

(2013) A. W. Johnson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chronic Exposure of Mutant DISC1 Mice to Lead Produces Sex-Dependent Abnormalities Consistent With Schizophrenia and Related Mental Disorders: A Gene-Environment Interaction Study

(2013) Bagrat Abazyan et al.   SCHIZOPHRENIA BULLETIN

The promise of N-acetylcysteine in neuropsychiatry

(2013) Michael Berk et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Neurodevelopmental disorders: mechanisms and boundary definitions from genomes, interactomes and proteomes

(2013) A P Mullin et al.   Translational Psychiatry

Maternofetal and neonatal copper requirements revealed by enterocyte-specific deletion of the Menkes disease protein

(2012) Yanfang Wang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Distinct and Overlapping Roles for AP-1 and GGAs Revealed by the “Knocksideways” System

(2012) Jennifer Hirst et al.   CURRENT BIOLOGY

Snapin is Critical for Presynaptic Homeostatic Plasticity

(2012) D. K. Dickman et al.   JOURNAL OF NEUROSCIENCE

Quantitative Proteomic and Genetic Analyses of the Schizophrenia Susceptibility Factor Dysbindin Identify Novel Roles of the Biogenesis of Lysosome-Related Organelles Complex 1

(2012) A. Gokhale et al.   JOURNAL OF NEUROSCIENCE

Modifiable risk factors for schizophrenia and autism — Shared risk factors impacting on brain development

(2012) Jess Hamlyn et al.   NEUROBIOLOGY OF DISEASE

Psychosis Induced by the Interaction Between Disulfiram and Methylphenidate May Be Dose Dependent

(2012) Lara Grau-López et al.   Substance Abuse

Dysbindin-1 gene contributes differentially to early- and adult-onset forms of functional psychosis

(2011) Mar Fatjó-Vilas et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Genetics of Schizophrenia: New Findings and Challenges

(2011) Pablo V. Gejman et al.   Annual Review of Genomics and Human Genetics

Dysbindin-Containing Complexes and their Proposed Functions in Brain: From Zero to (too) Many in a Decade

(2011) Cristina A Ghiani et al.   ASN Neuro

Linkage analysis of plasma dopamine β-hydroxylase activity in families of patients with schizophrenia

(2011) Joseph F. Cubells et al.   HUMAN GENETICS

Clusterin and COMMD1 Independently Regulate Degradation of the Mammalian Copper ATPases ATP7A and ATP7B

(2011) Stephanie Materia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cell Biology of the BLOC-1 Complex Subunit Dysbindin, a Schizophrenia Susceptibility Gene

(2011) Ariana P. Mullin et al.   MOLECULAR NEUROBIOLOGY

Dysbindin-1, a schizophrenia-related protein, facilitates neurite outgrowth by promoting the transcriptional activity of p53

(2011) X Ma et al.   MOLECULAR PSYCHIATRY

ATP7A-related copper transport diseases—emerging concepts and future trends

(2011) Stephen G. Kaler   Nature Reviews Neurology

Drosophila melanogaster: A new model to study cisplatin-induced neurotoxicity

(2011) Jewel L. Podratz et al.   NEUROBIOLOGY OF DISEASE

Is lead exposure in early life an environmental risk factor for Schizophrenia? Neurobiological connections and testable hypotheses

(2011) Tomás R. Guilarte et al.   NEUROTOXICOLOGY

Synaptic Dysbindin-1 Reductions in Schizophrenia Occur in an Isoform-Specific Manner Indicating Their Subsynaptic Location

(2011) Konrad Talbot et al.   PLoS One

Schizophrenia susceptibility gene dysbindin regulates glutamatergic and dopaminergic functions via distinctive mechanisms in Drosophila

(2011) L. Shao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recovery of Behavioral Changes and Compromised White Matter in C57BL/6 Mice Exposed to Cuprizone: Effects of Antipsychotic Drugs

(2011) Haiyun Xu et al.   Frontiers in Behavioral Neuroscience

Dysbindin-1, WAVE2 and Abi-1 form a complex that regulates dendritic spine formation

(2010) H Ito et al.   MOLECULAR PSYCHIATRY

Disulfiram Attenuates Drug-Primed Reinstatement of Cocaine Seeking via Inhibition of Dopamine β-Hydroxylase

(2010) Jason P Schroeder et al.   NEUROPSYCHOPHARMACOLOGY

Behavioral and neurobiological changes in C57BL/6 mice exposed to cuprizone.

(2009) Haiyun Xu et al.   BEHAVIORAL NEUROSCIENCE

Genetic modifiers of abnormal organelle biogenesis in a Drosophila model of BLOC-1 deficiency

(2009) Verónica T. Cheli et al.   HUMAN MOLECULAR GENETICS

Dysbindin-1 in dorsolateral prefrontal cortex of schizophrenia cases is reduced in an isoform-specific manner unrelated to dysbindin-1 mRNA expression

(2009) J. Tang et al.   HUMAN MOLECULAR GENETICS

Pronounced Paranoia as a Result of Cocaine-Disulfiram Interaction

(2009) Jochen Mutschler et al.   JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY

The dysbindin-containing complex (BLOC-1) in brain: developmental regulation, interaction with SNARE proteins and role in neurite outgrowth

(2009) C A Ghiani et al.   MOLECULAR PSYCHIATRY

The Schizophrenia Susceptibility Gene dysbindin Controls Synaptic Homeostasis

(2009) D. K. Dickman et al.   SCIENCE

Cell-specific ATP7A transport sustains copper-dependent tyrosinase activity in melanosomes

(2008) Subba Rao Gangi Setty et al.   NATURE

Dominant psychiatric manifestations in Wilson's disease: A diagnostic and therapeutic challenge!

(2007) K. Srinivas et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES