A Founder Mutation in VPS11 Causes an Autosomal Recessive Leukoencephalopathy Linked to Autophagic Defects

PLEKHM1 Regulates Autophagosome-Lysosome Fusion through HOPS Complex and LC3/GABARAP Proteins

(2015) David G. McEwan et al.   MOLECULAR CELL

A clinical approach to the diagnosis of patients with leukodystrophies and genetic leukoencephelopathies

(2015) Sumit Parikh et al.   MOLECULAR GENETICS AND METABOLISM

Case definition and classification of leukodystrophies and leukoencephalopathies

(2015) Adeline Vanderver et al.   MOLECULAR GENETICS AND METABOLISM

Biallelic mutations in SNX14 cause a syndromic form of cerebellar atrophy and lysosome-autophagosome dysfunction

(2015) Naiara Akizu et al.   NATURE GENETICS

Neuronal activity biases axon selection for myelination in vivo

(2015) Jacob H Hines et al.   NATURE NEUROSCIENCE

Small-Molecule Control of Intracellular Protein Levels through Modulation of the Ubiquitin Proteasome System

(2014) Dennis L. Buckley et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Autophagy and Its Normal and Pathogenic States in the Brain

(2014) Ai Yamamoto et al.   Annual Review of Neuroscience

Emerging therapies targeting the ubiquitin proteasome system in cancer

(2014) Nathaniel M. Weathington et al.   JOURNAL OF CLINICAL INVESTIGATION

The HOPS complex mediates autophagosome–lysosome fusion through interaction with syntaxin 17

(2014) Peidu Jiang et al.   MOLECULAR BIOLOGY OF THE CELL

Interaction of the HOPS complex with Syntaxin 17 mediates autophagosome clearance in Drosophila

(2014) Szabolcs Takáts et al.   MOLECULAR BIOLOGY OF THE CELL

High throughput screening for inhibitors of the HECT ubiquitin E3 ligase ITCH identifies antidepressant drugs as regulators of autophagy

(2014) M Rossi et al.   Cell Death & Disease

CORVET and HOPS tethering complexes - coordinators of endosome and lysosome fusion

(2013) H. J. k. Balderhaar et al.   JOURNAL OF CELL SCIENCE

Clinical Whole-Exome Sequencing for the Diagnosis of Mendelian Disorders

(2013) Yaping Yang et al.   NEW ENGLAND JOURNAL OF MEDICINE

Maintenance of Melanophore Morphology and Survival Is Cathepsin and vps11 Dependent in Zebrafish

(2013) Lauren F. Clancey et al.   PLoS One

Thromboxane A2 modulates cisplatin-induced apoptosis through a Siva1-dependent mechanism

(2012) C Iorio-Morin et al.   CELL DEATH AND DIFFERENTIATION

Molecular architecture of the multisubunit homotypic fusion and vacuole protein sorting (HOPS) tethering complex

(2012) C. Brocker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Subunit organization and Rab interactions of Vps-C protein complexes that control endolysosomal membrane traffic

(2011) Rachael L. Plemel et al.   MOLECULAR BIOLOGY OF THE CELL

RINGs hold the key to ubiquitin transfer

(2011) Rhesa Budhidarmo et al.   TRENDS IN BIOCHEMICAL SCIENCES

Lipid metabolism in myelinating glial cells: lessons from human inherited disorders and mouse models

(2010) Roman Chrast et al.   JOURNAL OF LIPID RESEARCH

Autophagy gone awry in neurodegenerative diseases

(2010) Esther Wong et al.   NATURE NEUROSCIENCE

Loss of human Greatwall results in G2 arrest and multiple mitotic defects due to deregulation of the cyclin B-Cdc2/PP2A balance

(2010) Andrew Burgess et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuronal loss in Pelizaeus–Merzbacher disease differs in various mutations of the proteolipid protein 1

(2009) Anders A. F. Sima et al.   ACTA NEUROPATHOLOGICA

Vps-C complexes: gatekeepers of endolysosomal traffic

(2009) Daniel P Nickerson et al.   CURRENT OPINION IN CELL BIOLOGY

Quantifying Western blots: Pitfalls of densitometry

(2009) Max Gassmann et al.   ELECTROPHORESIS

Autophagy regulates lipid metabolism

(2009) Rajat Singh et al.   NATURE

Invited Article: An MRI-based approach to the diagnosis of white matter disorders

(2009) R. Schiffmann et al.   NEUROLOGY

Characterization of Müller glia and neuronal progenitors during adult zebrafish retinal regeneration

(2008) Ryan Thummel et al.   EXPERIMENTAL EYE RESEARCH

Autoubiquitination of BCA2 RING E3 Ligase Regulates Its Own Stability and Affects Cell Migration

(2008) Y. Amemiya et al.   MOLECULAR CANCER RESEARCH