Caenorhabditis elegans HOPS and CCZ-1 mediate trafficking to lysosome-related organelles independently of RAB-7 and SAND-1

Lysosome-related organelles: unusual compartments become mainstream

(2013) Michael S Marks et al.   CURRENT OPINION IN CELL BIOLOGY

Tethering complexes in the endocytic pathway: CORVET and HOPS

(2013) Jachen A. Solinger et al.   FEBS Journal

Guanine Nucleotide Exchange Factors (GEFs) Have a Critical but Not Exclusive Role in Organelle Localization of Rab GTPases

(2013) Margarita Cabrera et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dmon1 controls recruitment of Rab7 to maturing endosomes in Drosophila

(2013) J. Yousefian et al.   JOURNAL OF CELL SCIENCE

CORVET and HOPS tethering complexes - coordinators of endosome and lysosome fusion

(2013) H. J. k. Balderhaar et al.   JOURNAL OF CELL SCIENCE

Syntaxin-3 Is Required for Melanosomal Localization of Tyrp1 in Melanocytes

(2013) Ayaka Yatsu et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

MXL-3 and HLH-30 transcriptionally link lipolysis and autophagy to nutrient availability

(2013) Eyleen J. O’Rourke et al.   NATURE CELL BIOLOGY

Structural basis of Vps33A recruitment to the human HOPS complex by Vps16

(2013) S. C. Graham et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Longin and GAF Domains: Structural Evolution and Adaptation to the Subcellular Trafficking Machinery

(2013) Nicola De Franceschi et al.   TRAFFIC

Anthranilate Fluorescence Marks a Calcium-Propagated Necrotic Wave That Promotes Organismal Death in C. elegans

(2013) Cassandra Coburn et al.   PLOS BIOLOGY

A divalent interaction between HPS1 and HPS4 is required for the formation of the biogenesis of lysosome-related organelle complex-3 (BLOC-3)

(2012) Carmelo Carmona-Rivera et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Mechanism of platelet dense granule biogenesis: study of cargo transport and function of Rab32 and Rab38 in a model system

(2012) A. L. Ambrosio et al.   BLOOD

The VPS33B-binding protein VPS16B is required in megakaryocyte and platelet  -granule biogenesis

(2012) D. Urban et al.   BLOOD

Untangling the evolution of Rab G proteins: implications of a comprehensive genomic analysis

(2012) Tobias H Klöpper et al.   BMC BIOLOGY

Lysosome-Related Organelles in Intestinal Cells Are a Zinc Storage Site in C. elegans

(2012) Hyun Cheol Roh et al.   Cell Metabolism

BLOC-3 Mutated in Hermansky-Pudlak Syndrome Is a Rab32/38 Guanine Nucleotide Exchange Factor

(2012) Andreas Gerondopoulos et al.   CURRENT BIOLOGY

Spatial Restriction of Bone Morphogenetic Protein Signaling in Mouse Gastrula through the mVam2-Dependent Endocytic Pathway

(2012) Minako Aoyama et al.   DEVELOPMENTAL CELL

Ablation of Vacuole Protein Sorting 18 (Vps18) Gene Leads to Neurodegeneration and Impaired Neuronal Migration by Disrupting Multiple Vesicle Transport Pathways to Lysosomes

(2012) Chao Peng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Ras protein superfamily: Evolutionary tree and role of conserved amino acids

(2012) Ana Maria Rojas et al.   JOURNAL OF CELL BIOLOGY

C. elegans BLOC-1 Functions in Trafficking to Lysosome-Related Gut Granules

(2012) Greg J. Hermann et al.   PLoS One

The C. elegans Rab Family: Identification, Classification and Toolkit Construction

(2012) Maria E. Gallegos et al.   PLoS One

The HOPS Proteins hVps41 and hVps39 Are Required for Homotypic and Heterotypic Late Endosome Fusion

(2012) Maaike S. Pols et al.   TRAFFIC

Rab38 targets to lamellar bodies and normalizes their sizes in lung alveolar type II epithelial cells

(2011) Linghui Zhang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Membrane dynamics and fusion at late endosomes and vacuoles – Rab regulation, multisubunit tethering complexes and SNAREs

(2011) Nadine Epp et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Lysosomal Trafficking, Antigen Presentation, and Microbial Killing Are Controlled by the Arf-like GTPase Arl8b

(2011) Salil Garg et al.   IMMUNITY

DENN Domain Proteins: Regulators of Rab GTPases

(2011) Andrea L. Marat et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Clathrin-dependent mechanisms modulate the subcellular distribution of class C Vps/HOPS tether subunits in polarized and nonpolarized cells

(2011) Stephanie A. Zlatic et al.   MOLECULAR BIOLOGY OF THE CELL

Subunit organization and Rab interactions of Vps-C protein complexes that control endolysosomal membrane traffic

(2011) Rachael L. Plemel et al.   MOLECULAR BIOLOGY OF THE CELL

Semi-Automated Analysis of Organelle Movement and Membrane Content: Understanding Rab-Motor Complex Transport Function

(2011) Alistair N. Hume et al.   TRAFFIC

Roles of CUP-5, the Caenorhabditis elegans orthologue of human TRPML1, in lysosome and gut granule biogenesis

(2010) Erin M Campbell et al.   BMC CELL BIOLOGY

Identification of the Switch in Early-to-Late Endosome Transition

(2010) Dmitry Poteryaev et al.   CELL

The Mon1-Ccz1 Complex Is the GEF of the Late Endosomal Rab7 Homolog Ypt7

(2010) Mirjana Nordmann et al.   CURRENT BIOLOGY

A Caenorhabditis elegans model of orotic aciduria reveals enlarged lysosome-related organelles in embryos lacking umps-1 function

(2010) Steven Levitte et al.   FEBS Journal

The TGF-β signaling modulators TRAP1/TGFBRAP1 and VPS39/Vam6/TLP are essential for early embryonic development

(2010) Sabine Messler et al.   IMMUNOBIOLOGY

Structure-Function Analysis of VPS9-Ankyrin-repeat Protein (Varp) in the Trafficking of Tyrosinase-related Protein 1 in Melanocytes

(2010) Kanako Tamura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphorylation of a membrane curvature–sensing motif switches function of the HOPS subunit Vps41 in membrane tethering

(2010) Margarita Cabrera et al.   JOURNAL OF CELL BIOLOGY

ccz-1 mediates the digestion of apoptotic corpses in C. elegans

(2010) C. Nieto et al.   JOURNAL OF CELL SCIENCE

Rab7 is a critical mediator in vesicular transport of tyrosinase-related protein 1 in melanocytes

(2010) Tokimasa HIDA et al.   JOURNAL OF DERMATOLOGY

The Arf-like GTPase Arl8 Mediates Delivery of Endocytosed Macromolecules to Lysosomes in Caenorhabditis elegans

(2010) Isei Nakae et al.   MOLECULAR BIOLOGY OF THE CELL

HOPS Initiates Vacuole Docking by Tethering Membranes before trans-SNARE Complex Assembly

(2010) Christopher M. Hickey et al.   MOLECULAR BIOLOGY OF THE CELL

Identification of two evolutionarily conserved genes regulating processing of engulfed apoptotic cells

(2010) Jason M. Kinchen et al.   NATURE

Evolution of acidocalcisomes and their role in polyphosphate storage and osmoregulation in eukaryotic microbes

(2010) R. Docampo et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

A Monoclonal Antibody Toolkit for C. elegans

(2010) Gayla Hadwiger et al.   PLoS One

Defined Subunit Arrangement and Rab Interactions Are Required for Functionality of the HOPS Tethering Complex

(2010) Clemens W. Ostrowicz et al.   TRAFFIC

C. elegans Major Fats Are Stored in Vesicles Distinct from Lysosome-Related Organelles

(2009) Eyleen J. O'Rourke et al.   Cell Metabolism

AP-3-dependent trafficking and disease: the first decade

(2009) Esteban C Dell’Angelica   CURRENT OPINION IN CELL BIOLOGY

Vps-C complexes: gatekeepers of endolysosomal traffic

(2009) Daniel P Nickerson et al.   CURRENT OPINION IN CELL BIOLOGY

The Cation Diffusion Facilitator Gene cdf-2 Mediates Zinc Metabolism in Caenorhabditis elegans

(2009) Diana E. Davis et al.   GENETICS

Disease mutations in Rab7 result in unregulated nucleotide exchange and inappropriate activation

(2009) Brett A. McCray et al.   HUMAN MOLECULAR GENETICS

Solution Structure of Human ζ-COP: Direct Evidences for Structural Similarity between COP I and Clathrin-Adaptor Coats

(2009) Wenyu Yu et al.   JOURNAL OF MOLECULAR BIOLOGY

The SM Protein Car/Vps33A Regulates SNARE-mediated Trafficking to Lysosomes and Lysosome-related Organelles

(2009) Mohammed A. Akbar et al.   MOLECULAR BIOLOGY OF THE CELL

HOPS Interacts with Apl5 at the Vacuole Membrane and Is Required for Consumption of AP-3 Transport Vesicles

(2009) Cortney G. Angers et al.   MOLECULAR BIOLOGY OF THE CELL

The dysbindin-containing complex (BLOC-1) in brain: developmental regulation, interaction with SNARE proteins and role in neurite outgrowth

(2009) C A Ghiani et al.   MOLECULAR PSYCHIATRY

Silencing by small RNAs is linked to endosomal trafficking

(2009) Young Sik Lee et al.   NATURE CELL BIOLOGY

Disorders of Lysosome-Related Organelle Biogenesis: Clinical and Molecular Genetics

(2008) Marjan Huizing et al.   Annual Review of Genomics and Human Genetics

Defective Lamellar Granule Secretion in Arthrogryposis, Renal Dysfunction, and Cholestasis Syndrome Caused by a Mutation in VPS33B

(2008) Dov Hershkovitz et al.   ARCHIVES OF DERMATOLOGY

glo-3, a Novel Caenorhabditis elegans Gene, Is Required for Lysosome-Related Organelle Biogenesis

(2008) B. M. Rabbitts et al.   GENETICS

Efficient termination of vacuolar Rab GTPase signaling requires coordinated action by a GAP and a protein kinase

(2008) Christopher L. Brett et al.   JOURNAL OF CELL BIOLOGY

Lysosome Biogenesis Mediated by vps-18 Affects Apoptotic Cell Degradation in Caenorhabditis elegans

(2008) Hui Xiao et al.   MOLECULAR BIOLOGY OF THE CELL

SPE-39 Family Proteins Interact with the HOPS Complex and Function in Lysosomal Delivery

(2008) Guang-dan Zhu et al.   MOLECULAR BIOLOGY OF THE CELL

A pathway for phagosome maturation during engulfment of apoptotic cells

(2008) Jason M. Kinchen et al.   NATURE CELL BIOLOGY

The Jpred 3 secondary structure prediction server

(2008) C. Cole et al.   NUCLEIC ACIDS RESEARCH

Phagocytic Receptor CED-1 Initiates a Signaling Pathway for Degrading Engulfed Apoptotic Cells

(2008) Xiaomeng Yu et al.   PLOS BIOLOGY

Rab7 Regulates Maturation of Melanosomal Matrix Protein gp100/Pmel17/Silv

(2007) Akinori Kawakami et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY