ACaenorhabditis elegansHomologue of LYST Functions in Endosome and Lysosome-Related Organelle Biogenesis

Regulation of Body Fat inCaenorhabditis elegans

(2015) Supriya Srinivasan   Annual Review of Physiology

Patients with LRBA deficiency show CTLA4 loss and immune dysregulation responsive to abatacept therapy

(2015) B. Lo et al.   SCIENCE

Lysosomal signaling molecules regulate longevity in Caenorhabditis elegans

(2015) A. Folick et al.   SCIENCE

LYST Controls the Biogenesis of the Endosomal Compartment Required for Secretory Lysosome Function

(2015) Fernando E. Sepulveda et al.   TRAFFIC

The BEACH Domain Protein SPIRRIG Is Essential for Arabidopsis Salt Stress Tolerance and Functions as a Regulator of Transcript Stabilization and Localization

(2015) Alexandra Steffens et al.   PLOS BIOLOGY

Assessing Cholesterol Storage in Live Cells and C. elegans by Stimulated Raman Scattering Imaging of Phenyl-Diyne Cholesterol

(2015) Hyeon Jeong Lee et al.   Scientific Reports

The ESCRT machinery: From the plasma membrane to endosomes and back again

(2014) Amber L. Schuh et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Dictyostelium LvsB has a regulatory role in endosomal vesicle fusion

(2014) Kristin Falkenstein et al.   JOURNAL OF CELL SCIENCE

Caenorhabditis elegans HOPS and CCZ-1 mediate trafficking to lysosome-related organelles independently of RAB-7 and SAND-1

(2014) Jared L. Delahaye et al.   MOLECULAR BIOLOGY OF THE CELL

CDD: NCBI's conserved domain database

(2014) Aron Marchler-Bauer et al.   NUCLEIC ACIDS RESEARCH

Endosome maturation, transport and functions

(2014) Cameron C. Scott et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

LYST Affects Lysosome Size and Quantity, but not Trafficking or Degradation Through Autophagy or Endocytosis

(2014) Petter Holland et al.   TRAFFIC

Lysosome-related organelles: unusual compartments become mainstream

(2013) Michael S Marks et al.   CURRENT OPINION IN CELL BIOLOGY

The million mutation project: A new approach to genetics in Caenorhabditis elegans

(2013) O. Thompson et al.   GENOME RESEARCH

Antagonistic Control of Lysosomal Fusion by Rab14 and the Lyst-Related Protein LvsB

(2013) Elena Kypri et al.   TRAFFIC

The BEACH Is Hot: A LYST of Emerging Roles for BEACH-Domain Containing Proteins in Human Disease

(2013) Andrew R. Cullinane et al.   TRAFFIC

The role of ALFY in selective autophagy

(2012) P Isakson et al.   CELL DEATH AND DIFFERENTIATION

Lysosome-Related Organelles in Intestinal Cells Are a Zinc Storage Site in C. elegans

(2012) Hyun Cheol Roh et al.   Cell Metabolism

Correlation between platelet phenotype and NBEAL2 genotype in patients with congenital thrombocytopenia and  -granule deficiency

(2012) R. Bottega et al.   HAEMATOLOGICA

Caenorhabditis elegans screen reveals role of PAR-5 in RAB-11-recycling endosome positioning and apicobasal cell polarity

(2012) Julia Franziska Winter et al.   NATURE CELL BIOLOGY

C. elegans BLOC-1 Functions in Trafficking to Lysosome-Related Gut Granules

(2012) Greg J. Hermann et al.   PLoS One

Nematode sperm maturation triggered by protease involves sperm-secreted serine protease inhibitor (Serpin)

(2012) Y. Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Drosophila mauveMutants Reveal a Role of LYST Homologs Late in the Maturation of Phagosomes and Autophagosomes

(2012) Mokhlasur Rahman et al.   TRAFFIC

Inhibition of P-glycoprotein enhances sensitivity of Caenorhabditis elegans to ivermectin

(2012) Bernadette F. Ardelli et al.   VETERINARY PARASITOLOGY

Mutations in NBEAL2, encoding a BEACH protein, cause gray platelet syndrome

(2011) Walter HA Kahr et al.   NATURE GENETICS

Exome sequencing identifies NBEAL2 as the causative gene for gray platelet syndrome

(2011) Cornelis A Albers et al.   NATURE GENETICS

NBEAL2 is mutated in gray platelet syndrome and is required for biogenesis of platelet α-granules

(2011) Meral Gunay-Aygun et al.   NATURE GENETICS

The Enlarged Lysosomes in beigej Cells Result From Decreased Lysosome Fission and Not Increased Lysosome Fusion

(2011) Nina Durchfort et al.   TRAFFIC

Roles of CUP-5, the Caenorhabditis elegans orthologue of human TRPML1, in lysosome and gut granule biogenesis

(2010) Erin M Campbell et al.   BMC CELL BIOLOGY

A Caenorhabditis elegans model of orotic aciduria reveals enlarged lysosome-related organelles in embryos lacking umps-1 function

(2010) Steven Levitte et al.   FEBS Journal

The Arf-like GTPase Arl8 Mediates Delivery of Endocytosed Macromolecules to Lysosomes in Caenorhabditis elegans

(2010) Isei Nakae et al.   MOLECULAR BIOLOGY OF THE CELL

A Monoclonal Antibody Toolkit for C. elegans

(2010) Gayla Hadwiger et al.   PLoS One

Chediak-Higashi syndrome

(2009) Jerry Kaplan et al.   CURRENT OPINION IN HEMATOLOGY

The Cation Diffusion Facilitator Gene cdf-2 Mediates Zinc Metabolism in Caenorhabditis elegans

(2009) Diana E. Davis et al.   GENETICS

The cell morphogenesis geneSPIRRIGin Arabidopsis encodes a WD/BEACH domain protein

(2009) Rainer Saedler et al.   PLANT JOURNAL

glo-3, a Novel Caenorhabditis elegans Gene, Is Required for Lysosome-Related Organelle Biogenesis

(2008) B. M. Rabbitts et al.   GENETICS

Phagocytic Receptor CED-1 Initiates a Signaling Pathway for Degrading Engulfed Apoptotic Cells

(2008) Xiaomeng Yu et al.   PLOS BIOLOGY