The Rab7 effector PLEKHM1 binds Arl8b to promote cargo traffic to lysosomes

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

(2016) Daniel J Klionsky et al.   Autophagy

RAB2A controls MT1‐MMP endocytic and E‐cadherin polarized Golgi trafficking to promote invasive breast cancer programs

(2016) Hiroaki Kajiho et al.   EMBO REPORTS

The position of lysosomes within the cell determines their luminal pH

(2016) Danielle E. Johnson et al.   JOURNAL OF CELL BIOLOGY

Mechanisms and functions of lysosome positioning

(2016) Jing Pu et al.   JOURNAL OF CELL SCIENCE

A molecular mechanism to regulate lysosome motility for lysosome positioning and tubulation

(2016) Xinran Li et al.   NATURE CELL BIOLOGY

Cholesterol and ORP1L-mediated ER contact sites control autophagosome transport and fusion with the endocytic pathway

(2016) Ruud H. Wijdeven et al.   Nature Communications

The Arf-like GTPase Arl8b is essential for three-dimensional invasive growth of prostate cancer in vitro and xenograft formation and growth in vivo

(2016) Samantha S. Dykes et al.   Oncotarget

PLEKHM1 Regulates Salmonella-Containing Vacuole Biogenesis and Infection

(2015) David G. McEwan et al.   Cell Host & Microbe

The small GTPase Arl8b regulates assembly of the mammalian HOPS complex on lysosomes

(2015) D. Khatter et al.   JOURNAL OF CELL SCIENCE

MHC Class II Presentation Is Controlled by the Lysosomal Small GTPase, Arl8b

(2015) Xavier Michelet et al.   JOURNAL OF IMMUNOLOGY

PLEKHM1 Regulates Autophagosome-Lysosome Fusion through HOPS Complex and LC3/GABARAP Proteins

(2015) David G. McEwan et al.   MOLECULAR CELL

TRAFD1 (FLN29) Interacts with Plekhm1 and Regulates Osteoclast Acidification and Resorption

(2015) Hanna Witwicka et al.   PLoS One

The late endosomal p14–MP1 (LAMTOR2/3) complex regulates focal adhesion dynamics during cell migration

(2014) Natalia Schiefermeier et al.   JOURNAL OF CELL BIOLOGY

The HOPS complex mediates autophagosome–lysosome fusion through interaction with syntaxin 17

(2014) Peidu Jiang et al.   MOLECULAR BIOLOGY OF THE CELL

Novel Functions for the Endocytic Regulatory Proteins MICAL-L1 and EHD1 in Mitosis

(2014) James B. Reinecke et al.   TRAFFIC

RILP interacts with HOPS complex via VPS41 subunit to regulate endocytic trafficking

(2014) Xiaosi Lin et al.   Scientific Reports

Late endosomal transport and tethering are coupled processes controlled by RILP and the cholesterol sensor ORP1L

(2013) R. van der Kant et al.   JOURNAL OF CELL SCIENCE

CORVET and HOPS tethering complexes - coordinators of endosome and lysosome fusion

(2013) H. J. k. Balderhaar et al.   JOURNAL OF CELL SCIENCE

Arf-like GTPase Arl8b regulates lytic granule polarization and natural killer cell–mediated cytotoxicity

(2013) Amit Tuli et al.   MOLECULAR BIOLOGY OF THE CELL

Rab7 and Arl8 GTPases are Necessary for Lysosome Tubulation in Macrophages

(2012) Amra Mrakovic et al.   TRAFFIC

Arl8 and SKIP Act Together to Link Lysosomes to Kinesin-1

(2011) Cláudia Rosa-Ferreira et al.   DEVELOPMENTAL CELL

Lysosomal Trafficking, Antigen Presentation, and Microbial Killing Are Controlled by the Arf-like GTPase Arl8b

(2011) Salil Garg et al.   IMMUNITY

Lysosomal positioning coordinates cellular nutrient responses

(2011) Viktor I. Korolchuk et al.   NATURE CELL BIOLOGY

Rab7: Role of its protein interaction cascades in endo-lysosomal traffic

(2010) Tuanlao Wang et al.   CELLULAR SIGNALLING

FYCO1 is a Rab7 effector that binds to LC3 and PI3P to mediate microtubule plus end–directed vesicle transport

(2010) Serhiy Pankiv et al.   JOURNAL OF CELL BIOLOGY

Rubicon and PLEKHM1 Negatively Regulate the Endocytic/Autophagic Pathway via a Novel Rab7-binding Domain

(2010) Keisuke Tabata et al.   MOLECULAR BIOLOGY OF THE CELL

Cholesterol sensor ORP1L contacts the ER protein VAP to control Rab7–RILP–p150Gluedand late endosome positioning

(2009) Nuno Rocha et al.   JOURNAL OF CELL BIOLOGY

Rab and Arl GTPase Family Members Cooperate in the Localization of the Golgin GCC185

(2008) Alondra Schweizer Burguete et al.   CELL