Breaking the Glyco-Code of HIV Persistence and Immunopathogenesis

Eradication of Triple-Negative Breast Cancer Cells by Targeting Glycosylated PD-L1

(2018) Chia-Wei Li et al.   CANCER CELL

Interleukin-10 Directly Inhibits CD8 + T Cell Function by Enhancing N-Glycan Branching to Decrease Antigen Sensitivity

(2018) Logan K. Smith et al.   IMMUNITY

HIV-1 replicates and persists in vaginal epithelial dendritic cells

(2018) Victor Pena-Cruz et al.   JOURNAL OF CLINICAL INVESTIGATION

Frontline Science: Plasma and immunoglobulin G galactosylation associate with HIV persistence during antiretroviral therapy

(2018) Surya Kumari Vadrevu et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Anti-HIV-1 antibody-dependent cellular cytotoxicity

(2018) Wen Shi Lee et al.   Current Opinion in HIV and AIDS

Plasma glycomics predict cardiovascular disease in patients with ART-controlled HIV infections

(2018) Douglas M. Oswald et al.   FASEB JOURNAL

Galectin-9 suppresses B cell receptor signaling and is regulated by I-branching of N-glycans

(2018) N. Giovannone et al.   Nature Communications

Galectin-9 binds IgM-BCR to regulate B cell signaling

(2018) Anh Cao et al.   Nature Communications

Mechanical properties of P-selectin PSGL-1 bonds

(2018) Bahman Farzi et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Galectin-9 binds to O-glycans on protein disulfide isomerase

(2017) Katrin Schaefer et al.   GLYCOBIOLOGY

The HIV-1 envelope glycoprotein structure: nailing down a moving target

(2017) Andrew B Ward et al.   IMMUNOLOGICAL REVIEWS

HIV persistence: clonal expansion of cells in the latent reservoir

(2017) Kyungyoon J. Kwon et al.   JOURNAL OF CLINICAL INVESTIGATION

Expansion of CD11b + Ly-6C + myeloid-derived suppressor cells (MDSCs) driven by galectin-9 attenuates CVB3-induced myocarditis

(2017) Yingying Zhang et al.   MOLECULAR IMMUNOLOGY

Re-evaluating evolution in the HIV reservoir

(2017) Daniel I. S. Rosenbloom et al.   NATURE

The Immunoregulatory Roles of Antibody Glycosylation

(2017) Madeleine F. Jennewein et al.   TRENDS IN IMMUNOLOGY

Langerhans Cells: the ‘Yin and Yang’ of HIV Restriction and Transmission

(2017) Luzia Mayr et al.   TRENDS IN MICROBIOLOGY

Galectin-3 captures interferon-gamma in the tumor matrix reducing chemokine gradient production and T-cell tumor infiltration

(2017) Monica Gordon-Alonso et al.   Nature Communications

Development of Sialic Acid-coated Nanoparticles for Targeting Cancer and Efficient Evasion of the Immune System

(2017) Young-Hwa Kim et al.   Theranostics

Blockage of Core Fucosylation Reduces Cell-Surface Expression of PD-1 and Promotes Anti-tumor Immune Responses of T Cells

(2017) Masahiro Okada et al.   Cell Reports

Aging in HIV-Infected Subjects: A New Scenario and a New View

(2017) Eugenia Negredo et al.   Biomed Research International

Broadly Neutralizing Antibodies as Treatment: Effects on Virus and Immune System

(2017) Jinal N. Bhiman et al.   Current HIV/AIDS Reports

Antibody-Dependent Cellular Cytotoxicity Activity of Effector Cells from HIV-Infected Elite and Viral Controllers

(2016) Gamze Isitman et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Galectin-3 binds highly galactosylated IgG1 and is crucial for the IgG1 complex mediated inhibition of C5aReceptor induced immune responses

(2016) Kerstin A. Heyl et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Glycoblotting method allows for rapid and efficient glycome profiling of human Alzheimer's disease brain, serum and cerebrospinal fluid towards potential biomarker discovery

(2016) Solomon T. Gizaw et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

A Genetic Modifier of the Gut Microbiome Influences the Risk of Graft-versus-Host Disease and Bacteremia After Hematopoietic Stem Cell Transplantation

(2016) Ahmad Rayes et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Ageing and inflammation in patients with HIV infection

(2016) M. Nasi et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

IgG Glycome in Colorectal Cancer

(2016) F. Vuckovic et al.   CLINICAL CANCER RESEARCH

Harnessing Fc receptor biology in the design of therapeutic antibodies

(2016) Peter Sondermann et al.   CURRENT OPINION IN IMMUNOLOGY

Engineered CAR T Cells Targeting the Cancer-Associated Tn-Glycoform of the Membrane Mucin MUC1 Control Adenocarcinoma

(2016) Avery D. Posey et al.   IMMUNITY

Do Biomarkers of Inflammation, Monocyte Activation, and Altered Coagulation Explain Excess Mortality Between HIV Infected and Uninfected People?

(2016) Kaku A. So-Armah et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Glycan Bound to the Selectin Low Affinity State Engages Glu-88 to Stabilize the High Affinity State under Force

(2016) Padmaja Mehta-D'souza et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Towards HIV-1 remission: potential roles for broadly neutralizing antibodies

(2016) Ariel Halper-Stromberg et al.   JOURNAL OF CLINICAL INVESTIGATION

The Latent Reservoir for HIV-1: How Immunologic Memory and Clonal Expansion Contribute to HIV-1 Persistence

(2016) Alexandra J. Murray et al.   JOURNAL OF IMMUNOLOGY

Profiling IgG N-glycans as potential biomarker of chronological and biological ages

(2016) Xinwei Yu et al.   MEDICINE

Fc-galactosylation modulates antibody-dependent cellular cytotoxicity of therapeutic antibodies

(2016) Marco Thomann et al.   MOLECULAR IMMUNOLOGY

Core 1– and 3–derived O-glycans collectively maintain the colonic mucus barrier and protect against spontaneous colitis in mice

(2016) K Bergstrom et al.   Mucosal Immunology

Persistent HIV-1 replication maintains the tissue reservoir during therapy

(2016) Ramon Lorenzo-Redondo et al.   NATURE

Epithelial glycosylation in gut homeostasis and inflammation

(2016) Yoshiyuki Goto et al.   NATURE IMMUNOLOGY

Precision glycocalyx editing as a strategy for cancer immunotherapy

(2016) Han Xiao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glycosylation and stabilization of programmed death ligand-1 suppresses T-cell activity

(2016) Chia-Wei Li et al.   Nature Communications

Identification of Siglec-1 null individuals infected with HIV-1

(2016) Javier Martinez-Picado et al.   Nature Communications

Elimination of HIV-1-infected cells by broadly neutralizing antibodies

(2016) Timothée Bruel et al.   Nature Communications

Trends in life expectancy of HIV-positive adults on antiretroviral therapy across the globe

(2016) Gilles Wandeler et al.   Current Opinion in HIV and AIDS

Human Galectin-9 Is a Potent Mediator of HIV Transcription and Reactivation

(2016) Mohamed Abdel-Mohsen et al.   PLoS Pathogens

D-Dimer Levels before HIV Seroconversion Remain Elevated Even after Viral Suppression and Are Associated with an Increased Risk of Non-AIDS Events

(2016) Matthew S. Freiberg et al.   PLoS One

Mapping the complete glycoproteome of virion-derived HIV-1 gp120 provides insights into broadly neutralizing antibody binding

(2016) Maria Panico et al.   Scientific Reports

Development of Globo-H Cancer Vaccine

(2015) Samuel J. Danishefsky et al.   ACCOUNTS OF CHEMICAL RESEARCH

Select host restriction factors are associated with HIV persistence during antiretroviral therapy

(2015) Mohamed Abdel-Mohsen et al.   AIDS

Inflammaging and Anti-Inflammaging: The Role of Cytokines in Extreme Longevity

(2015) Paola Lucia Minciullo et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

CD8 T-Cell Expansion and Inflammation Linked to CMV Coinfection in ART-treated HIV Infection

(2015) Michael L. Freeman et al.   CLINICAL INFECTIOUS DISEASES

Inflammatory Bowel Disease Associates with Proinflammatory Potential of the Immunoglobulin G Glycome

(2015) Irena Trbojević Akmačić et al.   INFLAMMATORY BOWEL DISEASES

Early HIV-1 Infection Is Associated With Reduced Frequencies of Cervical Th17 Cells

(2015) Lyle R. McKinnon et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Impact of Exogenous Galectin-9 on Human T Cells

(2015) Claire Lhuillier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Intestinal Fucose as a Mediator of Host–Microbe Symbiosis

(2015) Joseph M. Pickard et al.   JOURNAL OF IMMUNOLOGY

Factors Associated With Plasma IL-6 Levels During HIV Infection

(2015) Álvaro H. Borges et al.   JOURNAL OF INFECTIOUS DISEASES

Genetic susceptibility factors for alcohol-induced chronic pancreatitis

(2015) Ali A. Aghdassi et al.   PANCREATOLOGY

Controlled tetra-Fc sialylation of IVIg results in a drug candidate with consistent enhanced anti-inflammatory activity

(2015) Nathaniel Washburn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting Siglecs with a sialic acid–decorated nanoparticle abrogates inflammation

(2015) Shaun Spence et al.   Science Translational Medicine

Pre-B cell receptor binding to galectin-1 modifies galectin-1/carbohydrate affinity to modulate specific galectin-1/glycan lattice interactions

(2015) Jeremy Bonzi et al.   Nature Communications

HIV Latency Is Established Directly and Early in Both Resting and Activated Primary CD4 T Cells

(2015) Leonard Chavez et al.   PLoS Pathogens

Association of Systemic Lupus Erythematosus With Decreased Immunosuppressive Potential of the IgG Glycome

(2015) Frano Vučković et al.   Arthritis & Rheumatology

Galectin-3 Shapes Antitumor Immune Responses by Suppressing CD8+ T Cells via LAG-3 and Inhibiting Expansion of Plasmacytoid Dendritic Cells

(2015) T. Kouo et al.   Cancer Immunology Research

HIV and the Gut Microbiota, Partners in Crime: Breaking the Vicious Cycle to Unearth New Therapeutic Targets

(2015) Kishanda Vyboh et al.   Journal of Immunology Research

Maternal fucosyltransferase 2 status affects the gut bifidobacterial communities of breastfed infants

(2015) Zachery T Lewis et al.   Microbiome

Role of Mannose-Binding Lectin Deficiency in HIV-1 and Schistosoma Infections in a Rural Adult Population in Zimbabwe

(2015) Rutendo B. L. Zinyama-Gutsire et al.   PLoS One

Identification of antibody glycosylation structures that predict monoclonal antibody Fc-effector function

(2014) Amy W. Chung et al.   AIDS

Galectin-9 Is Rapidly Released During Acute HIV-1 Infection and Remains Sustained at High Levels Despite Viral Suppression Even in Elite Controllers

(2014) Ravi Tandon et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

A cross-sectional, population-based study measuring comorbidity among people living with HIV in Ontario

(2014) Claire E Kendall et al.   BMC PUBLIC HEALTH

Epithelial IL-22RA1-Mediated Fucosylation Promotes Intestinal Colonization Resistance to an Opportunistic Pathogen

(2014) Tu Anh N. Pham et al.   Cell Host & Microbe

Galectin-9-CD44 Interaction Enhances Stability and Function of Adaptive Regulatory T Cells

(2014) Chuan Wu et al.   IMMUNITY

Tumor-released Galectin-3, a Soluble Inhibitory Ligand of Human NKp30, Plays an Important Role in Tumor Escape from NK Cell Attack

(2014) Wei Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Antibody-Dependent Effector Functions Against HIV Decline in Subjects Receiving Antiretroviral Therapy

(2014) V. Madhavi et al.   JOURNAL OF INFECTIOUS DISEASES

Structural Characterization of Anti-Inflammatory Immunoglobulin G Fc Proteins

(2014) Alysia A. Ahmed et al.   JOURNAL OF MOLECULAR BIOLOGY

Chronic Inflammation (Inflammaging) and Its Potential Contribution to Age-Associated Diseases

(2014) C. Franceschi et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Rapid fucosylation of intestinal epithelium sustains host–commensal symbiosis in sickness

(2014) Joseph M. Pickard et al.   NATURE

Recent strategies targeting HIV glycans in vaccine design

(2014) Satoru Horiya et al.   Nature Chemical Biology

Obinutuzumab plus Chlorambucil in Patients with CLL and Coexisting Conditions

(2014) Valentin Goede et al.   NEW ENGLAND JOURNAL OF MEDICINE

Increased Risk of Serious Non-AIDS-Related Events in HIV-Infected Subjects on Antiretroviral Therapy Associated with a Low CD4/CD8 Ratio

(2014) Sergio Serrano-Villar et al.   PLoS One

Surfactant Protein D Inhibits HIV-1 Infection of Target Cells via Interference with gp120-CD4 Interaction and Modulates Pro-Inflammatory Cytokine Production

(2014) Hrishikesh Pandit et al.   PLoS One

Emerging Principles for the Therapeutic Exploitation of Glycosylation

(2014) Martin Dalziel et al.   SCIENCE

Innate lymphoid cells regulate intestinal epithelial cell glycosylation

(2014) Y. Goto et al.   SCIENCE

Initiation of ART during Early Acute HIV Infection Preserves Mucosal Th17 Function and Reverses HIV-Related Immune Activation

(2014) Alexandra Schuetz et al.   PLoS Pathogens

A Novel Protein Glycan Biomarker and Future Cardiovascular Disease Events

(2014) Akintunde O. Akinkuolie et al.   Journal of the American Heart Association

Antigen targeting to dendritic cells combined with transient regulatory T cell inhibition results in long-term tumor regression

(2014) Wendy WJ Unger et al.   OncoImmunology

Anti-citrullinated protein antibodies acquire a pro-inflammatory Fc glycosylation phenotype prior to the onset of rheumatoid arthritis

(2013) Yoann Rombouts et al.   ANNALS OF THE RHEUMATIC DISEASES

Glycosylation of Serum Proteins in Inflammatory Diseases

(2013) Olga Gornik et al.   DISEASE MARKERS

Decreasing mortality and changing patterns of causes of death in the Swiss HIV Cohort Study

(2013) R Weber et al.   HIV MEDICINE

Immune activation and HIV persistence: implications for curative approaches to HIV infection

(2013) Nichole R. Klatt et al.   IMMUNOLOGICAL REVIEWS

Natural variation in Fc glycosylation of HIV-specific antibodies impacts antiviral activity

(2013) Margaret E. Ackerman et al.   JOURNAL OF CLINICAL INVESTIGATION

Association of Functional Impairment with Inflammation and Immune Activation in HIV Type 1–Infected Adults Receiving Effective Antiretroviral Therapy

(2013) Kristine M. Erlandson, Amanda A. Allshouse, Catherine M. Jankowski, Eric J. Lee, Kevin M. Rufner, Brent E. Palmer et al.   JOURNAL OF INFECTIOUS DISEASES

Dissecting the Molecular Mechanism of IVIg Therapy: The Interaction between Serum IgG and DC-SIGN is Independent of Antibody Glycoform or Fc Domain

(2013) Xiaojie Yu et al.   JOURNAL OF MOLECULAR BIOLOGY

The Human Milk Metabolome Reveals Diverse Oligosaccharide Profiles

(2013) Jennifer T. Smilowitz et al.   JOURNAL OF NUTRITION

Galectin-9 Functionally Impairs Natural Killer Cells in Humans and Mice

(2013) L. Golden-Mason et al.   JOURNAL OF VIROLOGY

Glycans Are a Novel Biomarker of Chronological and Biological Ages

(2013) Jasminka Krištić et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Targeting Aberrant Sialylation in Cancer Cells Using a Fluorinated Sialic Acid Analog Impairs Adhesion, Migration, and In Vivo Tumor Growth

(2013) C. Bull et al.   MOLECULAR CANCER THERAPEUTICS

Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection

(2013) Gilad Doitsh et al.   NATURE

Glycocalyx engineering reveals a Siglec-based mechanism for NK cell immunoevasion

(2013) Jason E Hudak et al.   Nature Chemical Biology

Surfactant Protein D Modulates HIV Infection of Both T-Cells and Dendritic Cells

(2013) Jens Madsen et al.   PLoS One

Gag-Positive Reservoir Cells Are Susceptible to HIV-Specific Cytotoxic T Lymphocyte Mediated Clearance In Vitro and Can Be Detected In Vivo

(2013) Erin H. Graf et al.   PLoS One

Carbohydrate-based vaccines with a glycolipid adjuvant for breast cancer

(2013) Y.-L. Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

General mechanism for modulating immunoglobulin effector function

(2013) P. Sondermann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sialic acid-binding Ig-like lectin-7 interacts with HIV-1 gp120 and facilitates infection of CD4pos T cells and macrophages

(2013) Stefania Varchetta et al.   Retrovirology

Prevalence of HIV and chronic comorbidities among older adults

(2012) Joel Negin et al.   AIDS

MDSC

(2012) Bernard J.C. Macatangay et al.   AIDS

Chronic progressive HIV-1 infection is associated with elevated levels of myeloid-derived suppressor cells

(2012) Thomas Vollbrecht et al.   AIDS

Mortality in well controlled HIV in the continuous antiretroviral therapy arms of the SMART and ESPRIT trials compared with the general population

(2012) Alison J. Rodger et al.   AIDS

Dorsal Root Ganglia Damage in SIV-Infected Rhesus Macaques

(2012) Tricia H. Burdo et al.   AMERICAN JOURNAL OF PATHOLOGY

Multifarious roles of sialic acids in immunity

(2012) Ajit Varki et al.   Annals of the New York Academy of Sciences

Microbial Translocation Across the GI Tract

(2012) Jason M. Brenchley et al.   Annual Review of Immunology

Siglecs and Immune Regulation

(2012) Shiv Pillai et al.   Annual Review of Immunology

Galectin-9 binding to Tim-3 renders activated human CD4+ T cells less susceptible to HIV-1 infection

(2012) S. Elahi et al.   BLOOD

Stimulation of HIV-1-Specific Cytolytic T Lymphocytes Facilitates Elimination of Latent Viral Reservoir after Virus Reactivation

(2012) Liang Shan et al.   IMMUNITY

Structural Basis for Galectin-1-dependent Pre-B Cell Receptor (Pre-BCR) Activation

(2012) Latifa Elantak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inducible colitis-associated glycome capable of stimulating the proliferation of memory CD4+T cells

(2012) Atsushi Nishida et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Extended analysis of a genome-wide association study in primary sclerosing cholangitis detects multiple novel risk loci

(2012) Trine Folseraas et al.   JOURNAL OF HEPATOLOGY

Quantitative glycan profiling of normal human plasma derived immunoglobulin and its fragments Fab and Fc

(2012) Kalyan Rao Anumula   JOURNAL OF IMMUNOLOGICAL METHODS

Anti-inflammatory activity of IgG1 mediated by Fc galactosylation and association of FcγRIIB and dectin-1

(2012) Christian M Karsten et al.   NATURE MEDICINE

Vertebrate protein glycosylation: diversity, synthesis and function

(2012) Kelley W. Moremen et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A Plasma Biomarker Signature of Immune Activation in HIV Patients on Antiretroviral Therapy

(2012) Anupa Kamat et al.   PLoS One

HIV-1 incorporation of host-cell-derived glycosphingolipid GM3 allows for capture by mature dendritic cells

(2012) W. B. Puryear et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The role of sialic acid as a modulator of the anti-inflammatory activity of IgG

(2012) Sybille Böhm et al.   Seminars in Immunopathology

Siglec-1 Is a Novel Dendritic Cell Receptor That Mediates HIV-1 Trans-Infection Through Recognition of Viral Membrane Gangliosides

(2012) Nuria Izquierdo-Useros et al.   PLOS BIOLOGY

ADCC Develops Over Time during Persistent Infection with Live-Attenuated SIV and Is Associated with Complete Protection against SIVmac251 Challenge

(2012) Michael D. Alpert et al.   PLoS Pathogens

Markers of endothelial dysfunction, coagulation and tissue fibrosis independently predict venous thromboembolism in HIV

(2011) Laura W Musselwhite et al.   AIDS

Targeting Siglecs—A novel pharmacological strategy for immuno- and glycotherapy

(2011) Camilla Jandus et al.   BIOCHEMICAL PHARMACOLOGY

Urinary glycan markers for disease

(2011) Dominic S. Alonzi et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Bacteroides in the Infant Gut Consume Milk Oligosaccharides via Mucus-Utilization Pathways

(2011) Angela Marcobal et al.   Cell Host & Microbe

Morbidity and Aging in HIV-Infected Persons: The Swiss HIV Cohort Study

(2011) B. Hasse et al.   CLINICAL INFECTIOUS DISEASES

Premature Age-Related Comorbidities Among HIV-Infected Persons Compared With the General Population

(2011) G. Guaraldi et al.   CLINICAL INFECTIOUS DISEASES

A novel strategy for evasion of NK cell immunity by tumours expressing core2 O-glycans

(2011) Shigeru Tsuboi et al.   EMBO JOURNAL

Activation of NK Cells by ADCC Antibodies and HIV Disease Progression

(2011) Amy W Chung et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Loss of intestinal core 1–derived O-glycans causes spontaneous colitis in mice

(2011) Jianxin Fu et al.   JOURNAL OF CLINICAL INVESTIGATION

Attenuation of HIV-associated human B cell exhaustion by siRNA downregulation of inhibitory receptors

(2011) Lela Kardava et al.   JOURNAL OF CLINICAL INVESTIGATION

CD4 and CD8 T Cell Immune Activation during Chronic HIV Infection: Roles of Homeostasis, HIV, Type I IFN, and IL-7

(2011) M. Catalfamo et al.   JOURNAL OF IMMUNOLOGY

Plasma Levels of Soluble CD14 Independently Predict Mortality in HIV Infection

(2011) Netanya G. Sandler et al.   JOURNAL OF INFECTIOUS DISEASES

Novel Glycan Biomarkers for the Detection of Lung Cancer

(2011) James N. Arnold et al.   JOURNAL OF PROTEOME RESEARCH

High Throughput Isolation and Glycosylation Analysis of IgG–Variability and Heritability of the IgG Glycome in Three Isolated Human Populations

(2011) Maja Pučić et al.   MOLECULAR & CELLULAR PROTEOMICS

Intravenous gammaglobulin suppresses inflammation through a novel TH2 pathway

(2011) Robert M. Anthony et al.   NATURE

Phase III Multicenter Clinical Trial of the Sialyl-TN (STn)-Keyhole Limpet Hemocyanin (KLH) Vaccine for Metastatic Breast Cancer

(2011) D. Miles et al.   ONCOLOGIST

Siglecs Facilitate HIV-1 Infection of Macrophages through Adhesion with Viral Sialic Acids

(2011) Zhongcheng Zou et al.   PLoS One

Characterization of mannose-binding lectin plasma levels and genetic polymorphisms in HIV-1-infected individuals

(2011) Antonio Carlos Rosário Vallinoto et al.   Revista da Sociedade Brasileira de Medicina Tropical

Evolutionary Forces Shaping the Golgi Glycosylation Machinery: Why Cell Surface Glycans Are Universal to Living Cells

(2011) A. Varki   Cold Spring Harbor Perspectives in Biology

HIV Infection, Inflammation, Immunosenescence, and Aging

(2010) Steven G. Deeks   Annual Review of Medicine

Aberrant IgG galactosylation precedes disease onset, correlates with disease activity, and is prevalent in autoantibodies in rheumatoid arthritis

(2010) Altan Ercan et al.   ARTHRITIS AND RHEUMATISM

Distinct fucosylation of M cells and epithelial cells by Fut1 and Fut2, respectively, in response to intestinal environmental stress

(2010) Kazutaka Terahara et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Helicobacter pylori adhesion to gastric epithelial cells is mediated by glycan receptors

(2010) A. Magalhães et al.   BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH

Inhibition of N-linked glycosylation by tunicamycin induces E-cadherin-mediated cell–cell adhesion and inhibits cell proliferation in undifferentiated human colon cancer cells

(2010) Julio Cesar Madureira de Freitas Junior et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Superior In vivo Efficacy of Afucosylated Trastuzumab in the Treatment of HER2-Amplified Breast Cancer

(2010) Teemu T. Junttila et al.   CANCER RESEARCH

Effects of aging, body mass index, plasma lipid profiles, and smoking on human plasma N-glycans

(2010) Ana Knežević et al.   GLYCOBIOLOGY

Emerging Role of α2,6-Sialic Acid as a Negative Regulator of Galectin Binding and Function

(2010) Ya Zhuo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Novel Role for the IgG Fc Glycan: The Anti-inflammatory Activity of Sialylated IgG Fcs

(2010) Robert M. Anthony et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Neurocognitive impairment and psychiatric comorbidity in well-controlled human immunodeficiency virus–infected Thais from the 2NN Cohort Study

(2010) Wadchara Pumpradit et al.   JOURNAL OF NEUROVIROLOGY

Identification of N-Glycosylation Changes in the CSF and Serum in Patients with Schizophrenia

(2010) Johannes L. Stanta et al.   JOURNAL OF PROTEOME RESEARCH

MUC16 provides immune protection by inhibiting synapse formation between NK and ovarian tumor cells

(2010) Jennifer AA Gubbels et al.   Molecular Cancer

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

(2010) Andre Franke et al.   NATURE GENETICS

Cytomegalovirus-Specific T Cells Persist at Very High Levels during Long-Term Antiretroviral Treatment of HIV Disease

(2010) David M. Naeger et al.   PLoS One

Biomarkers of immune dysfunction in HIV

(2010) Daniel E Nixon et al.   Current Opinion in HIV and AIDS

HIV-1 Induces DCIR Expression in CD4+ T Cells

(2010) Alexandra A. Lambert et al.   PLoS Pathogens

Revisiting Immune Exhaustion During HIV Infection

(2010) Alka Khaitan et al.   Current HIV/AIDS Reports

The decreased expression of Siglec-7 represents an early marker of dysfunctional natural killer-cell subsets associated with high levels of HIV-1 viremia

(2009) E. Brunetta et al.   BLOOD

Secondary Failure of Metformin Monotherapy in Clinical Practice

(2009) J. B. Brown et al.   DIABETES CARE

Fut2-null mice display an altered glycosylation profile and impaired BabA-mediated Helicobacter pylori adhesion to gastric mucosa

(2009) Ana Magalhães et al.   GLYCOBIOLOGY

Risk factors for incident diabetes mellitus among HIV-infected patients receiving combination antiretroviral therapy in Taiwan: a case-control study

(2009) Y-C Lo et al.   HIV MEDICINE

Activation and Coagulation Biomarkers Are Independent Predictors of the Development of Opportunistic Disease in Patients with HIV Infection

(2009) Alison J. Rodger et al.   JOURNAL OF INFECTIOUS DISEASES

Initiation of the alternative pathway of murine complement by immune complexes is dependent onN-glycans in IgG antibodies

(2008) Nirmal K. Banda et al.   ARTHRITIS AND RHEUMATISM

The C-type lectin surface receptor DCIR acts as a new attachment factor for HIV-1 in dendritic cells and contributes to trans- and cis-infection pathways

(2008) A. A. Lambert et al.   BLOOD

Evidence for HIV-associated B cell exhaustion in a dysfunctional memory B cell compartment in HIV-infected viremic individuals

(2008) Susan Moir et al.   JOURNAL OF EXPERIMENTAL MEDICINE

NK cells in HIV-1 infection: evidence for their role in the control of HIV-1 infection

(2008) G. Alter et al.   JOURNAL OF INTERNAL MEDICINE

Infection byHelicobacter pyloriexpressing the BabA adhesin is influenced by the secretor phenotype

(2008) M Azevedo et al.   JOURNAL OF PATHOLOGY

Effective CD4+ T-cell restoration in gut-associated lymphoid tissue of HIV-infected patients is associated with enhanced Th17 cells and polyfunctional HIV-specific T-cell responses

(2008) M Macal et al.   Mucosal Immunology

A unified vision of the building blocks of life

(2008) Jamey D. Marth   NATURE CELL BIOLOGY

Identification of a receptor required for the anti-inflammatory activity of IVIG

(2008) R. M. Anthony et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recapitulation of IVIG Anti-Inflammatory Activity with a Recombinant IgG Fc

(2008) R. M. Anthony et al.   SCIENCE

Inflammatory and Coagulation Biomarkers and Mortality in Patients with HIV Infection

(2008) Lewis H Kuller et al.   PLOS MEDICINE