Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection

The Dendritic Cell Lineage: Ontogeny and Function of Dendritic Cells and Their Subsets in the Steady State and the Inflamed Setting

(2013) Miriam Merad et al.   Annual Review of Immunology

HIV-1 causes CD4 cell death through DNA-dependent protein kinase during viral integration

(2013) Arik Cooper et al.   NATURE

SAMHD1 restricts HIV-1 infection in resting CD4+ T cells

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SAMHD1 restricts HIV-1 reverse transcription in quiescent CD4+ T-cells

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Endogenous APOBEC3B Restricts LINE-1 Retrotransposition in Transformed Cells and Human Embryonic Stem Cells

(2011) Silke Wissing et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cumulative mechanisms of lymphoid tissue fibrosis and T cell depletion in HIV-1 and SIV infections

(2011) Ming Zeng et al.   JOURNAL OF CLINICAL INVESTIGATION

SAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction factor counteracted by Vpx

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Interleukin-1β Biosynthesis Inhibition Reduces Acute Seizures and Drug Resistant Chronic Epileptic Activity in Mice

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The Cytokine Release Inhibitory Drug CRID3 Targets ASC Oligomerisation in the NLRP3 and AIM2 Inflammasomes

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Innate Antiviral Response: Role in HIV-1 Infection

(2011) Paula M. Pitha   Viruses-Basel

CD4+ T Cell Depletion in Human Immunodeficiency Virus (HIV) Infection: Role of Apoptosis

(2011) Michèle Février et al.   Viruses-Basel

HIV Infection, Inflammation, Immunosenescence, and Aging

(2010) Steven G. Deeks   Annual Review of Medicine

The Inflammasomes

(2010) Kate Schroder et al.   CELL

Abortive HIV Infection Mediates CD4 T Cell Depletion and Inflammation in Human Lymphoid Tissue

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Manipulation of Host Cell Death Pathways during Microbial Infections

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A Highly Potent and Selective Caspase 1 Inhibitor that Utilizes a Key 3-Cyanopropanoic Acid Moiety

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Anti-inflammatory Compounds Parthenolide and Bay 11-7082 Are Direct Inhibitors of the Inflammasome

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Phosphorylation-Driven Assembly of the RIP1-RIP3 Complex Regulates Programmed Necrosis and Virus-Induced Inflammation

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Glyburide inhibits the Cryopyrin/Nalp3 inflammasome

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The CXCR4-Tropic Human Immunodeficiency Virus Envelope Promotes More-Efficient Gene Delivery to Resting CD4+ T Cells than the Vesicular Stomatitis Virus Glycoprotein G Envelope

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Roadblocks in HIV research: five questions

(2009) Clare Thomas   NATURE MEDICINE

Pyroptosis: host cell death and inflammation

(2009) Tessa Bergsbaken et al.   NATURE REVIEWS MICROBIOLOGY

The Inflammasomes

(2009) Mohamed Lamkanfi et al.   PLoS Pathogens

Differential requirement for the activation of the inflammasome for processing and release of IL-1  in monocytes and macrophages

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Preferential Cytolysis of Peripheral Memory CD4+ T Cells by In Vitro X4-Tropic Human Immunodeficiency Virus Type 1 Infection before the Completion of Reverse Transcription

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HIV-1 induced activation of CD4+ T cells creates new targets for HIV-1 infection in human lymphoid tissue ex vivo

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