New targeted therapies for breast cancer: A focus on tumor microenvironmental signals and chemoresistant breast cancers
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Title
New targeted therapies for breast cancer: A focus on tumor microenvironmental signals and chemoresistant breast cancers
Authors
Keywords
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Journal
World Journal of Clinical Cases
Volume 2, Issue 12, Pages 769
Publisher
Baishideng Publishing Group Inc.
Online
2014-12-19
DOI
10.12998/wjcc.v2.i12.769
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Note: Only part of the references are listed.- A Phase I Study of Capecitabine Combined with CPT-11 in Metastatic Breast Cancer Pretreated with Anthracyclines and Taxanes
- (2017) Masahiro Kashiwaba et al. ONCOLOGY
- Role of epigenetic mechanisms in epithelial-to-mesenchymal transition of breast cancer cells
- (2015) Annina Nickel et al. Translational Research
- CADe for Early Detection of Breast Cancer—Current Status and Why We Need to Continue to Explore New Approaches
- (2014) Robert M. Nishikawa et al. ACADEMIC RADIOLOGY
- The landscape of medical oncology in Europe by 2020
- (2014) E. de Azambuja et al. ANNALS OF ONCOLOGY
- Ado-trastuzumab Emtansine
- (2014) Patricia A. Corrigan et al. ANNALS OF PHARMACOTHERAPY
- Re-Excision Rates of Invasive Ductal Carcinoma with Lobular Features Compared with Invasive Ductal Carcinomas and Invasive Lobular Carcinomas of the Breast
- (2014) David P. Arps et al. ANNALS OF SURGICAL ONCOLOGY
- LRP4 induces extracellular matrix productions and facilitates chondrocyte differentiation
- (2014) Nobuyuki Asai et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
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- (2014) Vesna Brglez et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Why Are the Truncated Cyclin Es More Effective CDK2 Activators than the Full-Length Isoforms?
- (2014) Soumya Lipsa Rath et al. BIOCHEMISTRY
- KU004 induces G1 cell cycle arrest in human breast cancer SKBR-3 cells by modulating PI3K/Akt pathway
- (2014) Jing Fu et al. BIOMEDICINE & PHARMACOTHERAPY
- Rugulactone derivatives act as inhibitors of NF-κB activation and modulates the transcription of NF-κB dependent genes in MDA-MB-231cells
- (2014) Debendra K. Mohapatra et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Targeting cyclin-dependent kinase 1 (CDK1) but not CDK4/6 or CDK2 is selectively lethal to MYC-dependent human breast cancer cells
- (2014) Jian Kang et al. BMC CANCER
- mTORC1/C2 and pan-HDAC inhibitors synergistically impair breast cancer growth by convergent AKT and polysome inhibiting mechanisms
- (2014) Kathleen A. Wilson-Edell et al. BREAST CANCER RESEARCH AND TREATMENT
- Inhibition of histone demethylase, LSD2 (KDM1B), attenuates DNA methylation and increases sensitivity to DNMT inhibitor-induced apoptosis in breast cancer cells
- (2014) Tiffany A. Katz et al. BREAST CANCER RESEARCH AND TREATMENT
- Development and validation of a new algorithm for the reclassification of genetic variants identified in the BRCA1 and BRCA2 genes
- (2014) Dmitry Pruss et al. BREAST CANCER RESEARCH AND TREATMENT
- European Breast Cancer Service Screening Outcomes: A First Balance Sheet of the Benefits and Harms
- (2014) E. Paci et al. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
- 5-Aza-2-deoxycytidine and trichostatin A increase COUP-TFII expression in antiestrogen-resistant breast cancer cell lines
- (2014) Numan Al-Rayyan et al. CANCER LETTERS
- Cancer Stem-like Cells Derived from Chemoresistant Tumors Have a Unique Capacity to Prime Tumorigenic Myeloid Cells
- (2014) T. Yamashina et al. CANCER RESEARCH
- Myeloid WNT7b Mediates the Angiogenic Switch and Metastasis in Breast Cancer
- (2014) E.-J. Yeo et al. CANCER RESEARCH
- The Reprogramming of Tumor Stroma by HSF1 Is a Potent Enabler of Malignancy
- (2014) Ruth Scherz-Shouval et al. CELL
- Rottlerin induces Wnt co-receptor LRP6 degradation and suppresses both Wnt/β-catenin and mTORC1 signaling in prostate and breast cancer cells
- (2014) Wenyan Lu et al. CELLULAR SIGNALLING
- Re-expression and epigenetic modification of maspin induced apoptosis in MCF-7 cells mediated by myocardin
- (2014) Xing-Hua Liao et al. CELLULAR SIGNALLING
- Exposure–Response Relationship of T-DM1: Insight Into Dose Optimization for Patients With HER2-Positive Metastatic Breast Cancer
- (2014) J Wang et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Oestrogen receptor-alpha regulates non-canonical Hedgehog-signalling in the mammary gland
- (2014) Nadia Okolowsky et al. DEVELOPMENTAL BIOLOGY
- In situ proliferation contributes to accumulation of tumor-associated macrophages in spontaneous mammary tumors
- (2014) Piotr Tymoszuk et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Deoxyribonuclease inhibitors
- (2014) Ana Kolarevic et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Overview of cyclins D1 function in cancer and the CDK inhibitor landscape: past and present
- (2014) Mathew C Casimiro et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- CXCR3 deficiency enhances tumor progression by promoting macrophage M2 polarization in a murine breast cancer model
- (2014) Steve Oghumu et al. IMMUNOLOGY
- Neurotensin, a novel target of Wnt/β-catenin pathway, promotes growth of neuroendocrine tumor cells
- (2014) Ji Tae Kim et al. INTERNATIONAL JOURNAL OF CANCER
- Controversies in Breast Cancer Screening for Women Aged 40-49 Years
- (2014) A. Suzuki et al. JAPANESE JOURNAL OF CLINICAL ONCOLOGY
- Dimethyl Sulfoxide Suppresses Mouse 4T1 Breast Cancer Growth by Modulating Tumor-Associated Macrophage Differentiation
- (2014) Rui Deng et al. Journal of Breast Cancer
- Salinomycin Suppresses LRP6 Expression and Inhibits Both Wnt/β-catenin and mTORC1 Signaling in Breast and Prostate Cancer Cells
- (2014) Wenyan Lu et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Tumor-α9β1 integrin-mediated signaling induces breast cancer growth and lymphatic metastasis via the recruitment of cancer-associated fibroblasts
- (2014) Daichi Ota et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Mass Spectrometric Analysis of the Phosphorylation Levels of the SWI/SNF Chromatin Remodeling/Tumor Suppressor Proteins ARID1A and Brg1 in Ovarian Clear Cell Adenocarcinoma Cell Lines
- (2014) Ayuko Kimura et al. JOURNAL OF PROTEOME RESEARCH
- The γ-secretase inhibitor PF-03084014 combined with fludarabine antagonizes migration, invasion and angiogenesis in NOTCH1-mutated CLL cells
- (2014) M López-Guerra et al. LEUKEMIA
- Proteomic Analysis of the Human Cyclin-dependent Kinase Family Reveals a Novel CDK5 Complex Involved in Cell Growth and Migration
- (2014) Shuangbing Xu et al. MOLECULAR & CELLULAR PROTEOMICS
- VDR Status Arbitrates the Prometastatic Effects of Tumor-Associated Macrophages
- (2014) Yan Zhang et al. MOLECULAR CANCER RESEARCH
- Monensin Inhibits Canonical Wnt Signaling in Human Colorectal Cancer Cells and Suppresses Tumor Growth in Multiple Intestinal Neoplasia Mice
- (2014) L. Tumova et al. MOLECULAR CANCER THERAPEUTICS
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- (2014) Gauri Deb et al. MOLECULAR CARCINOGENESIS
- Tumor-Associated Macrophages are Correlated with Tamoxifen Resistance in the Postmenopausal Breast Cancer Patients
- (2014) Qi-jia Xuan et al. PATHOLOGY & ONCOLOGY RESEARCH
- Initial testing (stage 1) of the notch inhibitor PF-03084014, by the pediatric preclinical testing program
- (2014) Hernan Carol et al. PEDIATRIC BLOOD & CANCER
- Regulation of the Number of Cell Division Rounds by Tissue-Specific Transcription Factors and Cdk Inhibitor during Ascidian Embryogenesis
- (2014) Mami Kuwajima et al. PLoS One
- Trichostatin A Targets the Mitochondrial Respiratory Chain, Increasing Mitochondrial Reactive Oxygen Species Production to Trigger Apoptosis in Human Breast Cancer Cells
- (2014) Shujuan Sun et al. PLoS One
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- (2014) James J. Cody et al. PLoS One
- Glycerol-3-Phosphate Acyltranferase-2 Behaves as a Cancer Testis Gene and Promotes Growth and Tumorigenicity of the Breast Cancer MDA-MB-231 Cell Line
- (2014) Magali Pellon-Maison et al. PLoS One
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- (2014) Mao Ouyang et al. PLoS One
- Modulated Expression of Genes Encoding Estrogen Metabolizing Enzymes by G1-Phase Cyclin-Dependent Kinases 6 and 4 in Human Breast Cancer Cells
- (2014) Yi Jia et al. PLoS One
- Both Canonical and Non-Canonical Wnt Signaling Independently Promote Stem Cell Growth in Mammospheres
- (2014) Alexander M. Many et al. PLoS One
- Hypoxia-inducible factor-dependent signaling between triple-negative breast cancer cells and mesenchymal stem cells promotes macrophage recruitment
- (2014) P. Chaturvedi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A rationale to target the SWI/SNF complex for cancer therapy
- (2014) Anja F. Hohmann et al. TRENDS IN GENETICS
- BRCA2 Coordinates the Activities of Cell-Cycle Kinases to Promote Genome Stability
- (2014) Keiko Yata et al. Cell Reports
- Induction of Wnt-Inducible Signaling Protein-1 Correlates with Invasive Breast Cancer Oncogenesis and Reduced Type 1 Cell-Mediated Cytotoxic Immunity: A Retrospective Study
- (2014) David J. Klinke II PLoS Computational Biology
- Comparison of dynamic contrast-enhanced MR, ultrasound and optical imaging modalities to evaluate the antiangiogenic effect of PF-03084014 and sunitinib
- (2014) Cathy C. Zhang et al. Cancer Medicine
- The essential role of TNIK gene amplification in gastric cancer growth
- (2014) D-H Yu et al. Oncogenesis
- Identification and cost of adverse events in metastatic breast cancer in taxane and capecitabine based regimens
- (2014) Ryan N Hansen et al. SpringerPlus
- Simultaneous Expression of Cancer Stem Cell-Like Properties and Cancer-Associated Fibroblast-Like Properties in a Primary Culture of Breast Cancer Cells
- (2014) Mami Ishikawa et al. Cancers
- Cyclin-Dependent Kinase Inhibitor Dinaciclib Interacts with the Acetyl-Lysine Recognition Site of Bromodomains
- (2013) Mathew P. Martin et al. ACS Chemical Biology
- The National Prevention Strategy and Breast Cancer Screening: Scientific Evidence for Public Health Action
- (2013) Marcus Plescia et al. AMERICAN JOURNAL OF PUBLIC HEALTH
- Association of somatic DNA methylation variability with progression-free survival and toxicity in ovarian cancer patients
- (2013) J. M. Flanagan et al. ANNALS OF ONCOLOGY
- Importance of epigenetic changes in cancer etiology, pathogenesis, clinical profiling, and treatment: What can be learned from hematologic malignancies?
- (2013) Lorella Vecchio et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- A link between premenopausal iron deficiency and breast cancer malignancy
- (2013) Jinlong Jian et al. BMC CANCER
- The Wnt signalling pathway is upregulated in an in vitro model of acquired tamoxifen resistant breast cancer
- (2013) Yan Ni Loh et al. BMC CANCER
- Randomized phase II study of sunitinib versus standard of care for patients with previously treated advanced triple-negative breast cancer
- (2013) Giuseppe Curigliano et al. BREAST
- Fulvestrant induces resistance by modulating GPER and CDK6 expression: implication of methyltransferases, deacetylases and the hSWI/SNF chromatin remodelling complex
- (2013) B Giessrigl et al. BRITISH JOURNAL OF CANCER
- Tumours with elevated levels of the Notch and Wnt pathways exhibit efficacy to PF-03084014, a γ-secretase inhibitor, in a preclinical colorectal explant model
- (2013) J J Arcaroli et al. BRITISH JOURNAL OF CANCER
- Notch signaling pathway targeted therapy suppresses tumor progression and metastatic spread in pancreatic cancer
- (2013) Shinichi Yabuuchi et al. CANCER LETTERS
- Hbo1 Is a Cyclin E/CDK2 Substrate That Enriches Breast Cancer Stem-like Cells
- (2013) M. T. Duong et al. CANCER RESEARCH
- Tumor-Stroma Interaction: Revealing Fibroblast-Secreted Exosomes as Potent Regulators of Wnt-Planar Cell Polarity Signaling in Cancer Metastasis
- (2013) V. Luga et al. CANCER RESEARCH
- Adipocyte-Derived Fibroblasts Promote Tumor Progression and Contribute to the Desmoplastic Reaction in Breast Cancer
- (2013) L. Bochet et al. CANCER RESEARCH
- Compartment-specific activation of PPARγ governs breast cancer tumor growth, via metabolic reprogramming and symbiosis
- (2013) Paola Avena et al. CELL CYCLE
- Randomized Phase II Trial of the Cyclin-Dependent Kinase Inhibitor Dinaciclib (MK-7965) Versus Capecitabine in Patients With Advanced Breast Cancer
- (2013) Monica M. Mita et al. Clinical Breast Cancer
- The Histone Deacetylase Inhibitor Abexinostat Induces Cancer Stem Cells Differentiation in Breast Cancer with Low Xist Expression
- (2013) M. A. Salvador et al. CLINICAL CANCER RESEARCH
- Targeting Tyrosine Kinase Receptors in Hepatocellular Carcinoma
- (2013) Jordi Muntane et al. CURRENT CANCER DRUG TARGETS
- Triple negative breast cancer initiating cell subsets differ in functional and molecular characteristics and in γ-secretase inhibitor drug responses
- (2013) Diana J. Azzam et al. EMBO Molecular Medicine
- A phase two randomised trial of neratinib monotherapy versus lapatinib plus capecitabine combination therapy in patients with HER2+ advanced breast cancer
- (2013) Miguel Martin et al. EUROPEAN JOURNAL OF CANCER
- Palbociclib (PD 0332991): targeting the cell cycle machinery in breast cancer
- (2013) Andrea Rocca et al. EXPERT OPINION ON PHARMACOTHERAPY
- GPER activates Notch signaling in breast cancer cells and cancer-associated fibroblasts (CAFs)
- (2013) Marco Pupo et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Regulation of estrogen receptor β1 expression in breast cancer by epigenetic modification of the 5′ regulatory region
- (2013) HAKEEMAH AL-NAKHLE et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- A phase Ib combination study of RO4929097, a gamma-secretase inhibitor, and temsirolimus in patients with advanced solid tumors
- (2013) Ivan Diaz-Padilla et al. INVESTIGATIONAL NEW DRUGS
- A phase I study of the oral gamma secretase inhibitor R04929097 in combination with gemcitabine in patients with advanced solid tumors (PHL-078/CTEP 8575)
- (2013) Suzanne Richter et al. INVESTIGATIONAL NEW DRUGS
- Nonclassical Activation of Hedgehog Signaling Enhances Multidrug Resistance and Makes Cancer Cells Refractory to Smoothened-targeting Hedgehog Inhibition
- (2013) Shamik Das et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Randomized phase 2 study of the cyclin-dependent kinase inhibitor dinaciclib (MK-7965) versus erlotinib in patients with non-small cell lung cancer
- (2013) Joe J. Stephenson et al. LUNG CANCER
- Breast cancer screening: review of benefits and harms, and recommendations for developing and low-income countries
- (2013) Meteb Al-Foheidi et al. MEDICAL ONCOLOGY
- Dinaciclib (SCH727965) Inhibits the Unfolded Protein Response through a CDK1- and 5-Dependent Mechanism
- (2013) T. K. Nguyen et al. MOLECULAR CANCER THERAPEUTICS
- Tumor-Initiating Cells and FZD8 Play a Major Role in Drug Resistance in Triple-Negative Breast Cancer
- (2013) S. Yin et al. MOLECULAR CANCER THERAPEUTICS
- Breast Cancer in Young Women in Latin America: An Unmet, Growing Burden
- (2013) C. Villarreal-Garza et al. ONCOLOGIST
- Reactivation of Estrogen Receptor α by Vorinostat Sensitizes Mesenchymal-Like Triple-Negative Breast Cancer to Aminoflavone, a Ligand of the Aryl Hydrocarbon Receptor
- (2013) Karri Stark et al. PLoS One
- Wnt Pathway Activity in Breast Cancer Sub-Types and Stem-Like Cells
- (2013) Rebecca Lamb et al. PLoS One
- Eukaryotic Initiation Factor 2α - a Downstream Effector of Mammalian Target of Rapamycin - Modulates DNA Repair and Cancer Response to Treatment
- (2013) Liron Tuval-Kochen et al. PLoS One
- RB1 Status in Triple Negative Breast Cancer Cells Dictates Response to Radiation Treatment and Selective Therapeutic Drugs
- (2013) Tyler J. W. Robinson et al. PLoS One
- Suberoylanilide Hydroxamic Acid, an Inhibitor of Histone Deacetylase, Enhances Radiosensitivity and Suppresses Lung Metastasis in Breast Cancer In Vitro and In Vivo
- (2013) Hui-Wen Chiu et al. PLoS One
- Inactivating mutations of RNF43 confer Wnt dependency in pancreatic ductal adenocarcinoma
- (2013) X. Jiang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Targeting Wnt-driven cancer through the inhibition of Porcupine by LGK974
- (2013) J. Liu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Expression and regulatory function of miRNA-182 in triple-negative breast cancer cells through its targeting of profilin 1
- (2013) Hailing Liu et al. TUMOR BIOLOGY
- Comparison of the clinicopathological features of invasive ductal, invasive lobular, and mixed (invasive ductal + invasive lobular) carcinoma of the breast
- (2013) Baha Zengel et al. Breast Cancer
- The Hedgehog inhibitor cyclopamine antagonizes chemoresistance of breast cancer cells
- (2013) Jun Shi et al. OncoTargets and Therapy
- Wnt Signaling in Normal and Malignant Hematopoiesis
- (2013) W. Lento et al. Cold Spring Harbor Perspectives in Biology
- Linking Proteomic and Transcriptional Data through the Interactome and Epigenome Reveals a Map of Oncogene-induced Signaling
- (2013) Shao-shan Carol Huang et al. PLoS Computational Biology
- Synergistic Effect of the γ-Secretase Inhibitor PF-03084014 and Docetaxel in Breast Cancer Models
- (2013) Cathy C. Zhang et al. Stem Cells Translational Medicine
- Role of Hydroxamate-Based Histone Deacetylase Inhibitors (Hb-HDACIs) in the Treatment of Solid Malignancies
- (2013) Antonino Grassadonia et al. Cancers
- Normal hematopoiesis and hematologic malignancies: Role of canonical Wnt signaling pathway and stromal microenvironment
- (2012) Paul Faustin Seke Etet et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Pre-clinical studies of Notch signaling inhibitor RO4929097 in inflammatory breast cancer cells
- (2012) Bisrat G. Debeb et al. BREAST CANCER RESEARCH AND TREATMENT
- Stromal cells in tumor microenvironment and breast cancer
- (2012) Yan Mao et al. CANCER AND METASTASIS REVIEWS
- Pharmacological Inhibition of the Wnt Acyltransferase PORCN Prevents Growth of WNT-Driven Mammary Cancer
- (2012) K. D. Proffitt et al. CANCER RESEARCH
- Hedgehog Signaling Is a Novel Therapeutic Target in Tamoxifen-Resistant Breast Cancer Aberrantly Activated by PI3K/AKT Pathway
- (2012) B. Ramaswamy et al. CANCER RESEARCH
- Folate deprivation enhances invasiveness of human colon cancer cells mediated by activation of sonic hedgehog signaling through promoter hypomethylation and cross action with transcription nuclear factor-kappa B pathway
- (2012) Tz-Ping Wang et al. CARCINOGENESIS
- Therapeutic response to CDK4/6 inhibition in breast cancer defined by ex vivo analyses of human tumors
- (2012) Jeffry L. Dean et al. CELL CYCLE
- CDK4/6 inhibition antagonizes the cytotoxic response to anthracycline therapy
- (2012) A. Kathleen McClendon et al. CELL CYCLE
- Autophagy and senescence in cancer-associated fibroblasts metabolically supports tumor growth and metastasis, via glycolysis and ketone production
- (2012) Claudia Capparelli et al. CELL CYCLE
- CDK inhibitors (p16/p19/p21) induce senescence and autophagy in cancer-associated fibroblasts, “fueling” tumor growth via paracrine interactions, without an increase in neo-angiogenesis
- (2012) Claudia Capparelli et al. CELL CYCLE
- Signaling pathways bridging microbial-triggered inflammation and cancer
- (2012) Maulilio John Kipanyula et al. CELLULAR SIGNALLING
- Differential Pathological Response to Preoperative Chemotherapy across Breast Cancer Intrinsic Subtypes
- (2012) Hiromitsu Jinno et al. CHEMOTHERAPY
- Dipyridamole prevents triple-negative breast-cancer progression
- (2012) Daniela Spano et al. CLINICAL & EXPERIMENTAL METASTASIS
- Improved Outcome of High-Risk Early HER2 Positive Breast Cancer With High CXCL13-CXCR5 Messenger RNA Expression
- (2012) Evangelia Razis et al. Clinical Breast Cancer
- Biomarker and Pharmacologic Evaluation of the -Secretase Inhibitor PF-03084014 in Breast Cancer Models
- (2012) C. C. Zhang et al. CLINICAL CANCER RESEARCH
- In Vivo Phosphoantigen Levels in Bisphosphonate-Treated Human Breast Tumors Trigger V 9V 2 T-cell Antitumor Cytotoxicity through ICAM-1 Engagement
- (2012) I. Benzaid et al. CLINICAL CANCER RESEARCH
- Insulin resistance and cancer: the role of insulin and IGFs
- (2012) Sefirin Djiogue et al. ENDOCRINE-RELATED CANCER
- Ki-67 Index Guided Selection of Preoperative Chemotherapy for HER2-positive Breast Cancer: A Randomized Phase II Trial
- (2012) T. Yamaguchi et al. JAPANESE JOURNAL OF CLINICAL ONCOLOGY
- CXCL12/CXCR4 Protein Signaling Axis Induces Sonic Hedgehog Expression in Pancreatic Cancer Cells via Extracellular Regulated Kinase- and Akt Kinase-mediated Activation of Nuclear Factor κB
- (2012) Ajay P. Singh et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Wnt5a Induces a Tolerogenic Phenotype of Macrophages in Sepsis and Breast Cancer Patients
- (2012) C. Bergenfelz et al. JOURNAL OF IMMUNOLOGY
- Multiple Roles of Cyclin-Dependent Kinase 4/6 Inhibitors in Cancer Therapy
- (2012) Patrick J. Roberts et al. JNCI-Journal of the National Cancer Institute
- IT Future of Medicine: from molecular analysis to clinical diagnosis and improved treatment
- (2012) Valeria Zazzu et al. New Biotechnology
- Functional genomics identifies therapeutic targets for MYC-driven cancer
- (2012) M. Toyoshima et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Role of stromal cell-mediated Notch signaling in CLL resistance to chemotherapy
- (2012) A H Nwabo Kamdje et al. Blood Cancer Journal
- Notch-3 and Notch-4 signaling rescue from apoptosis human B-ALL cells in contact with human bone marrow-derived mesenchymal stromal cells
- (2011) A. H. Nwabo Kamdje et al. BLOOD
- GPER mediates the Egr-1 expression induced by 17β-estradiol and 4-hydroxitamoxifen in breast and endometrial cancer cells
- (2011) Adele Vivacqua et al. BREAST CANCER RESEARCH AND TREATMENT
- Targeting GLI1 expression in human inflammatory breast cancer cells enhances apoptosis and attenuates migration
- (2011) Z I Thomas et al. BRITISH JOURNAL OF CANCER
- Targeting both Notch and ErbB-2 signalling pathways is required for prevention of ErbB-2-positive breast tumour recurrence
- (2011) K Pandya et al. BRITISH JOURNAL OF CANCER
- Tumor-Derived Jagged1 Promotes Osteolytic Bone Metastasis of Breast Cancer by Engaging Notch Signaling in Bone Cells
- (2011) Nilay Sethi et al. CANCER CELL
- Gli1 enhances migration and invasion via up-regulation of MMP-11 and promotes metastasis in ERα negative breast cancer cell lines
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- The ZEB1/miR-200 feedback loop controls Notch signalling in cancer cells
- (2011) Simone Brabletz et al. EMBO JOURNAL
- Killing the second messenger: targeting loss of cell cycle control in endocrine-resistant breast cancer
- (2011) C. A. Lange et al. ENDOCRINE-RELATED CANCER
- Notch-1 and Notch-4 Biomarker Expression in Triple-Negative Breast Cancer
- (2011) Jodi Speiser et al. INTERNATIONAL JOURNAL OF SURGICAL PATHOLOGY
- Down regulation of CSL activity inhibits cell proliferation in prostate and breast cancer cells
- (2011) Thomas Yong et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Capecitabine Versus Classical Cyclophosphamide, Methotrexate, and Fluorouracil As First-Line Chemotherapy for Advanced Breast Cancer
- (2011) Martin R. Stockler et al. JOURNAL OF CLINICAL ONCOLOGY
- A chemical-genetic screen reveals a mechanism of resistance to PI3K inhibitors in cancer
- (2011) Markus K Muellner et al. Nature Chemical Biology
- Gamma-secretase inhibitors target tumor-initiating cells in a mouse model of ERBB2 breast cancer
- (2011) M Kondratyev et al. ONCOGENE
- Hypoxia-induced Jagged2 promotes breast cancer metastasis and self-renewal of cancer stem-like cells
- (2011) F Xing et al. ONCOGENE
- Maintenance of hormone responsiveness in luminal breast cancers by suppression of Notch
- (2011) J. M. Haughian et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A SUMOylation-Dependent Transcriptional Subprogram Is Required for Myc-Driven Tumorigenesis
- (2011) J. D. Kessler et al. SCIENCE
- RETRACTED ARTICLE: Platelet-derived growth factor-D contributes to aggressiveness of breast cancer cells by up-regulating Notch and NF-κB signaling pathways
- (2010) Aamir Ahmad et al. BREAST CANCER RESEARCH AND TREATMENT
- Synthetic Lethality through Combined Notch-Epidermal Growth Factor Receptor Pathway Inhibition in Basal-Like Breast Cancer
- (2010) Y. Dong et al. CANCER RESEARCH
- Downregulation of Notch Pathway by a -Secretase Inhibitor Attenuates AKT/Mammalian Target of Rapamycin Signaling and Glucose Uptake in an ERBB2 Transgenic Breast Cancer Model
- (2010) C. L. Efferson et al. CANCER RESEARCH
- Expression and regulation mechanisms of Sonic Hedgehog in breast cancer
- (2010) Wei Cui et al. CANCER SCIENCE
- A new mutation of BRCA2 gene in an Italian healthy woman with familial breast cancer history
- (2010) Maurizio Pisanò et al. Familial Cancer
- Dinaciclib (SCH 727965), a Novel and Potent Cyclin-Dependent Kinase Inhibitor
- (2010) David Parry et al. MOLECULAR CANCER THERAPEUTICS
- Evaluation of Selective -Secretase Inhibitor PF-03084014 for Its Antitumor Efficacy and Gastrointestinal Safety to Guide Optimal Clinical Trial Design
- (2010) P. Wei et al. MOLECULAR CANCER THERAPEUTICS
- The lymphovascular embolus of inflammatory breast cancer exhibits a Notch 3 addiction
- (2010) Y Xiao et al. ONCOGENE
- A mobile threat to genome stability: The impact of non-LTR retrotransposons upon the human genome
- (2010) Miriam K. Konkel et al. SEMINARS IN CANCER BIOLOGY
- Repression of Mammary Stem/Progenitor Cells by p53 Is Mediated by Notch and Separable from Apoptotic Activity
- (2010) Luwei Tao et al. STEM CELLS
- Discovery of Dinaciclib (SCH 727965): A Potent and Selective Inhibitor of Cyclin-Dependent Kinases
- (2010) Kamil Paruch et al. ACS Medicinal Chemistry Letters
- Inhibition of γ-secretase induces G2/M arrest and triggers apoptosis in breast cancer cells
- (2009) S Rasul et al. BRITISH JOURNAL OF CANCER
- Cross-Talk Between Notch and EGFR Signaling in Human Breast Cancer Cells
- (2009) Jianjian Dai et al. CANCER INVESTIGATION
- Preclinical Profile of a Potent -Secretase Inhibitor Targeting Notch Signaling with In vivo Efficacy and Pharmacodynamic Properties
- (2009) L. Luistro et al. CANCER RESEARCH
- Tumor-Initiating Cells of HER2-Positive Carcinoma Cell Lines Express the Highest Oncoprotein Levels and Are Sensitive to Trastuzumab
- (2009) A. Magnifico et al. CLINICAL CANCER RESEARCH
- Cooperation of Notch and Ras/MAPK signaling pathways in human breast carcinogenesis
- (2009) Suruchi Mittal et al. Molecular Cancer
- Mammalian cell-cycle regulation: several Cdks, numerous cyclins and diverse compensatory mechanisms
- (2009) A Satyanarayana et al. ONCOGENE
- Molecular Dependence of Estrogen Receptor-Negative Breast Cancer on a Notch-Survivin Signaling Axis
- (2008) C. W. Lee et al. CANCER RESEARCH
- Cross-talk between Notch and the Estrogen Receptor in Breast Cancer Suggests Novel Therapeutic Approaches
- (2008) P. Rizzo et al. CANCER RESEARCH
- Advancing Bioluminescence Imaging Technology for the Evaluation of Anticancer Agents in the MDA-MB-435-HAL-Luc Mammary Fat Pad and Subrenal Capsule Tumor Models
- (2008) C. Zhang et al. CLINICAL CANCER RESEARCH
- Characterization of sonic hedgehog as a novel NF-κB target gene that promotes NF-κB-mediated apoptosis resistance and tumor growth in vivo
- (2008) Hubert Kasperczyk et al. FASEB JOURNAL
- ErbB-2 inhibition activates Notch-1 and sensitizes breast cancer cells to a γ-secretase inhibitor
- (2008) C Osipo et al. ONCOGENE
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