Targeting GLI1 expression in human inflammatory breast cancer cells enhances apoptosis and attenuates migration

Characterization of the roles of RHOC and RHOA GTPases in invasion, motility, and matrix adhesion in inflammatory and aggressive breast cancers

(2010) Mei Wu et al.   CANCER

Is there a role for mammary stem cells in inflammatory breast carcinoma?

(2010) Steven Van Laere et al.   CANCER

Combinatorial Chemoprevention Reveals a Novel Smoothened-Independent Role of GLI1 in Esophageal Carcinogenesis

(2010) S. Rizvi et al.   CANCER RESEARCH

Hedgehog signaling pathway mediates the progression of non-invasive breast cancer to invasive breast cancer

(2010) Masae Souzaki et al.   CANCER SCIENCE

Hedgehog proteins activate pro-angiogenic responses in endothelial cells through non-canonical signaling pathways

(2010) Pilar Chinchilla et al.   CELL CYCLE

Evaluation of a CXCR4 antagonist in a xenograft mouse model of inflammatory breast cancer

(2010) Balraj Singh et al.   CLINICAL & EXPERIMENTAL METASTASIS

Overexpression of COX-2 in Celecoxib-Resistant Breast Cancer Cell Lines

(2010) Balraj Singh et al.   JOURNAL OF SURGICAL RESEARCH

CSPG4 Protein as a New Target for the Antibody-Based Immunotherapy of Triple-Negative Breast Cancer

(2010) Xinhui Wang et al.   JNCI-Journal of the National Cancer Institute

X-Linked Inhibitor of Apoptosis Protein Inhibits Apoptosis in Inflammatory Breast Cancer Cells with Acquired Resistance to an ErbB1/2 Tyrosine Kinase Inhibitor

(2010) K. M. Aird et al.   MOLECULAR CANCER THERAPEUTICS

Sonic Hedgehog/GLI1 signaling pathway inhibition restricts cell migration and invasion in human gliomas

(2010) Ke Wang et al.   NEUROLOGICAL RESEARCH

GLI1 facilitates the migration and invasion of pancreatic cancer cells through MUC5AC-mediated attenuation of E-cadherin

(2010) S Inaguma et al.   ONCOGENE

Context-dependent Regulation of the GLI Code in Cancer by HEDGEHOG and Non-HEDGEHOG Signals

(2010) B. Stecca et al.   Journal of Molecular Cell Biology

Expression of the glioma-associated oncogene homolog (GLI) 1in human breast cancer is associated with unfavourable overall survival

(2009) Anette ten Haaf et al.   BMC CANCER

Expression of Gli1 correlates with the transition of breast cancer cells to estrogen-independent growth

(2009) Jieying Zhao et al.   BREAST CANCER RESEARCH AND TREATMENT

Gli1 promotes cell survival and is predictive of a poor outcome in ERα-negative breast cancer

(2009) Lusheng Xu et al.   BREAST CANCER RESEARCH AND TREATMENT

Paracrine Hedgehog Signaling in Cancer

(2009) J.-W. Theunissen et al.   CANCER RESEARCH

Development of Mammary Tumors by Conditional Expression of GLI1

(2009) M. Fiaschi et al.   CANCER RESEARCH

A Novel Splice Variant of GLI1 That Promotes Glioblastoma Cell Migration and Invasion

(2009) H.-W. Lo et al.   CANCER RESEARCH

Hedgehog signalling: Emerging evidence for non-canonical pathways

(2009) Dagan Jenkins   CELLULAR SIGNALLING

Hedgehog Target Genes: Mechanisms of Carcinogenesis Induced by Aberrant Hedgehog Signaling Activation

(2009) Y. Katoh et al.   CURRENT MOLECULAR MEDICINE

GLI1 is regulated through Smoothened-independent mechanisms in neoplastic pancreatic ducts and mediates PDAC cell survival and transformation

(2009) O. Nolan-Stevaux et al.   GENES & DEVELOPMENT

The Hedgehog Pathway Transcription Factor GLI1 Promotes Malignant Behavior of Cancer Cells by Up-regulating Osteopontin

(2009) Shamik Das et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular targets for treatment of inflammatory breast cancer

(2009) Hideko Yamauchi et al.   Nature Reviews Clinical Oncology

Activation of the hedgehog-signaling pathway in human cancer and the clinical implications

(2009) L Yang et al.   ONCOGENE

Molecular Profiling of Breast Cancer Cell Lines Defines Relevant Tumor Models and Provides a Resource for Cancer Gene Discovery

(2009) Jessica Kao et al.   PLoS One

Small-molecule inhibitors reveal multiple strategies for Hedgehog pathway blockade

(2009) J. M. Hyman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanisms of Hedgehog pathway activation in cancer and implications for therapy

(2009) Suzie J. Scales et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Cyclopamine inhibition of human breast cancer cell growth independent of Smoothened (Smo)

(2008) Xiaomei Zhang et al.   BREAST CANCER RESEARCH AND TREATMENT

Gli1 contributes to the invasiveness of pancreatic cancer through matrix metalloproteinase-9 activation

(2008) Shuntaro Nagai et al.   CANCER SCIENCE

Naturally Occurring Small-Molecule Inhibitors of Hedgehog/GLI-Mediated Transcription

(2008) Takahiro Hosoya et al.   CHEMBIOCHEM

Trastuzumab signaling in ErbB2-overexpressing inflammatory breast cancer correlates with X-linked inhibitor of apoptosis protein expression

(2008) K. M. Aird et al.   MOLECULAR CANCER THERAPEUTICS

A paracrine requirement for hedgehog signalling in cancer

(2008) Robert L. Yauch et al.   NATURE

Primers on Molecular Pathways GLI: More than Just Hedgehog?

(2008) Martín E. Fernández-Zapico   PANCREATOLOGY