RB1 Status in Triple Negative Breast Cancer Cells Dictates Response to Radiation Treatment and Selective Therapeutic Drugs

Sequential chemoimmunotherapy of fludarabine, mitoxantrone, and cyclophosphamide induction followed by alemtuzumab consolidation is effective in T-cell prolymphocytic leukemia

(2013) Georg Hopfinger et al.   CANCER

High-throughput screen identifies disulfiram as a potential therapeutic for triple-negative breast cancer cells: Interaction with IQ motif-containing factors

(2013) Tyler Robinson et al.   CELL CYCLE

Computational modeling of apoptotic signaling pathways induced by cisplatin

(2012) Ji-Young Hong et al.   BMC Systems Biology

Cancer Stem Cells: Impact, Heterogeneity, and Uncertainty

(2012) Jeffrey A. Magee et al.   CANCER CELL

RB-Pathway Disruption Is Associated with Improved Response to Neoadjuvant Chemotherapy in Breast Cancer

(2012) A. K. Witkiewicz et al.   CLINICAL CANCER RESEARCH

Fludarabine and cytarabine in patients with relapsed acute myeloid leukemia refractory to initial salvage therapy

(2012) Brian McLaughlin et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

Sequence of Radiotherapy and Chemotherapy in Breast Cancer After Breast-Conserving Surgery

(2012) Jan J. Jobsen et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Comprehensive molecular portraits of human breast tumours

(2012) Daniel C. Koboldt et al.   NATURE

Assessment of Compound Hepatotoxicity Using Human Plateable Cryopreserved Hepatocytes in a 1536-Well-Plate Format

(2011) Timothy A. Moeller et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

RB1 and p53 at the crossroad of EMT and triple-negative breast cancer

(2011) Zhe Jiang et al.   CELL CYCLE

Phase I, Dose-Escalation Trial of the Oral Cyclin-Dependent Kinase 4/6 Inhibitor PD 0332991, Administered Using a 21-Day Schedule in Patients with Advanced Cancer

(2011) K. T. Flaherty et al.   CLINICAL CANCER RESEARCH

Molecular Stratification of Triple-Negative Breast Cancers

(2011) C. M. Perou   ONCOLOGIST

Preoperative radio-chemotherapy in early breast cancer patients: Long-term results of a phase II trial

(2011) Marc A. Bollet et al.   RADIOTHERAPY AND ONCOLOGY

RB-pathway disruption in breast cancer

(2010) Adam Ertel et al.   CELL CYCLE

Selective targeting of neuroblastoma tumour-initiating cells by compounds identified in stem cell-based small molecule screens

(2010) Kristen M. Smith et al.   EMBO Molecular Medicine

Rb deletion in mouse mammary progenitors induces luminal-B or basal-like/EMT tumor subtypes depending on p53 status

(2010) Zhe Jiang et al.   JOURNAL OF CLINICAL INVESTIGATION

A Repurposing Strategy Identifies Novel Synergistic Inhibitors ofPlasmodium falciparumHeat Shock Protein 90

(2010) Dea Shahinas et al.   JOURNAL OF MEDICINAL CHEMISTRY

Deconstructing the molecular portraits of breast cancer

(2010) Aleix Prat et al.   Molecular Oncology

Most Basal-like Breast Carcinomas Demonstrate the Same Rb−/p16+ Immunophenotype as the HPV-related Poorly Differentiated Squamous Cell Carcinomas Which They Resemble Morphologically

(2009) Andrea Proctor Subhawong et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

High prevalence of retinoblastoma protein loss in triple-negative breast cancers and its association with a good prognosis in patients treated with adjuvant chemotherapy

(2009) D. Trere et al.   ANNALS OF ONCOLOGY

HLA-matched allo-SCT after reduced intensity conditioning with fludarabine/CY in patients with metastatic breast cancer

(2009) A J H M Fleskens et al.   BONE MARROW TRANSPLANTATION

Distinct gene mutation profiles among luminal-type and basal-type breast cancer cell lines

(2009) Antoinette Hollestelle et al.   BREAST CANCER RESEARCH AND TREATMENT

PRIMA-1 Reactivates Mutant p53 by Covalent Binding to the Core Domain

(2009) Jeremy M.R. Lambert et al.   CANCER CELL

Characterization of a Naturally Occurring Breast Cancer Subset Enriched in Epithelial-to-Mesenchymal Transition and Stem Cell Characteristics

(2009) B. T. Hennessy et al.   CANCER RESEARCH

In vivo Antitumor Activity of MEK and Phosphatidylinositol 3-Kinase Inhibitors in Basal-Like Breast Cancer Models

(2009) K. P. Hoeflich et al.   CLINICAL CANCER RESEARCH

Pharmacotherapy of triple-negative breast cancer

(2009) Cagatay Arslan et al.   EXPERT OPINION ON PHARMACOTHERAPY

Pathologic Complete Response Rates in Young Women With BRCA1-Positive Breast Cancers After Neoadjuvant Chemotherapy

(2009) Tomasz Byrski et al.   JOURNAL OF CLINICAL ONCOLOGY

Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features

(2009) C. J. Creighton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pattern of metastatic spread in triple-negative breast cancer

(2008) Rebecca Dent et al.   BREAST CANCER RESEARCH AND TREATMENT

Loss of Retinoblastoma Tumor Suppressor Protein Makes Human Breast Cancer Cells More Sensitive to Antimetabolite Exposure

(2008) M. Derenzini et al.   CLINICAL CANCER RESEARCH

Intrinsic Resistance of Tumorigenic Breast Cancer Cells to Chemotherapy

(2008) X. Li et al.   JNCI-Journal of the National Cancer Institute