Inhibition of histone demethylase, LSD2 (KDM1B), attenuates DNA methylation and increases sensitivity to DNMT inhibitor-induced apoptosis in breast cancer cells

Crosstalk between lysine-specific demethylase 1 (LSD1) and histone deacetylases mediates antineoplastic efficacy of HDAC inhibitors in human breast cancer cells

(2013) Shauna N. Vasilatos et al.   CARCINOGENESIS

Lsd1 and Lsd2 Control Programmed Replication Fork Pauses and Imprinting in Fission Yeast

(2012) Allyson Holmes et al.   Cell Reports

Polyamine analogs modulate gene expression by inhibiting lysine-specific demethylase 1 (LSD1) and altering chromatin structure in human breast cancer cells

(2011) Qingsong Zhu et al.   AMINO ACIDS

Inhibitors of histone demethylation and histone deacetylation cooperate in regulating gene expression and inhibiting growth in human breast cancer cells

(2011) Yi Huang et al.   BREAST CANCER RESEARCH AND TREATMENT

A phase II study of the histone deacetylase inhibitor vorinostat combined with tamoxifen for the treatment of patients with hormone therapy-resistant breast cancer

(2011) P N Munster et al.   BRITISH JOURNAL OF CANCER

Progesterone Receptor Isoform-Specific Promoter Methylation: Association of PRA Promoter Methylation with Worse Outcome in Breast Cancer Patients

(2011) T. N. Pathiraja et al.   CLINICAL CANCER RESEARCH

AOF1 is a histone H3K4 demethylase possessing demethylase activity-independent repression function

(2010) Ze Yang et al.   CELL RESEARCH

Epigenetic Regulation in Estrogen Receptor Positive Breast Cancer—Role in Treatment Response

(2010) Thushangi N. Pathiraja et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

Human LSD2/KDM1b/AOF1 Regulates Gene Transcription by Modulating Intragenic H3K4me2 Methylation

(2010) Rui Fang et al.   MOLECULAR CELL

A Feed-Forward Circuit Controlling Inducible NF-κB Target Gene Activation by Promoter Histone Demethylation

(2010) Dominic van Essen et al.   MOLECULAR CELL

Lysine-specific demethylase 1 (LSD1) is highly expressed in ER-negative breast cancers and a biomarker predicting aggressive biology

(2009) Soyoung Lim et al.   CARCINOGENESIS

A Novel Mammalian Flavin-dependent Histone Demethylase

(2009) Aristotele Karytinos et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

KDM1B is a histone H3K4 demethylase required to establish maternal genomic imprints

(2009) David N. Ciccone et al.   NATURE

The prognostic importance of triple negative breast carcinoma

(2008) Hakan Mersin et al.   BREAST

Defining a Chromatin Pattern that Characterizes DNA-Hypermethylated Genes in Colon Cancer Cells

(2008) K. M. McGarvey et al.   CANCER RESEARCH

The lysine demethylase LSD1 (KDM1) is required for maintenance of global DNA methylation

(2008) Jing Wang et al.   NATURE GENETICS