标题
The hallmarks of aging in Ataxia-Telangiectasia
作者
关键词
-
出版物
AGEING RESEARCH REVIEWS
Volume 79, Issue -, Pages 101653
出版商
Elsevier BV
发表日期
2022-05-27
DOI
10.1016/j.arr.2022.101653
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Exploring aging interventions in human brain organoids
- (2022) Julio Aguado et al. Aging-US
- From DNA damage to mutations: all roads lead to aging
- (2021) Jan Vijg AGEING RESEARCH REVIEWS
- Senescent cells and the incidence of age‐related diseases
- (2021) Itay Katzir et al. AGING CELL
- Poly-ADP-ribosylation drives loss of protein homeostasis in ATM and Mre11 deficiency
- (2021) Ji-Hoon Lee et al. MOLECULAR CELL
- NAD + supplementation prevents STING‐induced senescence in ataxia telangiectasia by improving mitophagy
- (2021) Beimeng Yang et al. AGING CELL
- The central role of DNA damage in the ageing process
- (2021) Björn Schumacher et al. NATURE
- Inhibition of the cGAS‐STING pathway ameliorates the premature senescence hallmarks of Ataxia‐Telangiectasia brain organoids
- (2021) Julio Aguado et al. AGING CELL
- The role of retrotransposable elements in ageing and age-associated diseases
- (2021) Vera Gorbunova et al. NATURE
- A Novel Mechanism of Ataxia Telangiectasia Mutated Mediated Regulation of Chromatin Remodeling in Hypoxic Conditions
- (2021) Maria Likhatcheva et al. Frontiers in Cell and Developmental Biology
- Cytoplasmic DNA: sources, sensing, and role in aging and disease
- (2021) Karl N. Miller et al. CELL
- LARP7 ameliorates cellular senescence and aging by allosterically enhancing SIRT1 deacetylase activity
- (2021) Pengyi Yan et al. Cell Reports
- An anaplerotic approach to correct the mitochondrial dysfunction in ataxia-telangiectasia (A-T)
- (2021) A.J. Yeo et al. Molecular Metabolism
- Mitochondria-to-nucleus retrograde signaling drives formation of cytoplasmic chromatin and inflammation in senescence
- (2020) Maria Grazia Vizioli et al. GENES & DEVELOPMENT
- The ageing epigenome and its rejuvenation
- (2020) Weiqi Zhang et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- mTOR at the nexus of nutrition, growth, ageing and disease
- (2020) Grace Y. Liu et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Protecting the Aging Genome
- (2020) Michael A. Petr et al. TRENDS IN CELL BIOLOGY
- Cellular Senescence in Neurodegenerative Diseases
- (2020) Carmen Martínez-Cué et al. Frontiers in Cellular Neuroscience
- SIRT6 is a DNA double-strand break sensor
- (2020) Lior Onn et al. eLife
- Checkpoint Responses to DNA Double-Strand Breaks
- (2020) David P. Waterman et al. Annual Review of Biochemistry
- How do cells sense DNA lesions?
- (2020) Chiara Vittoria Colombo et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- The role of cellular senescence in ageing and endocrine disease
- (2020) Sundeep Khosla et al. Nature Reviews Endocrinology
- Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
- (2020) Helmut Sies et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- DNA methylation and gene expression signatures are associated with ataxia-telangiectasia phenotype
- (2020) Sharon A. McGrath-Morrow et al. Scientific Reports
- Mitochondria at the crossroads of ATM-mediated stress signaling and regulation of reactive oxygen species
- (2020) Ji-Hoon Lee et al. Redox Biology
- Regulation of senescence traits by MAPKs
- (2020) Carlos Anerillas et al. GeroScience
- Mitophagy: An Emerging Role in Aging and Age-Associated Diseases
- (2020) Guo Chen et al. Frontiers in Cell and Developmental Biology
- Classical and Nonclassical Intercellular Communication in Senescence and Ageing
- (2020) Juan Antonio Fafián-Labora et al. TRENDS IN CELL BIOLOGY
- Diabetes in Patients With Ataxia Telangiectasia: A National Cohort Study
- (2020) Helena Donath et al. Frontiers in Pediatrics
- ATM-associated signalling triggers the unfolded protein response and cell death in response to stress
- (2020) Yuka Hotokezaka et al. Communications Biology
- Telomere transcription in ageing
- (2020) Julio Aguado et al. AGEING RESEARCH REVIEWS
- ATM-deficient neural precursors develop senescence phenotype with disturbances in autophagy
- (2020) Piotr Sunderland et al. MECHANISMS OF AGEING AND DEVELOPMENT
- The critical roles of somatic mutations and environmental tumor-promoting agents in cancer risk
- (2020) Allan Balmain NATURE GENETICS
- Phosphoproteomics reveals novel modes of function and inter‐relationships among PIKKs in response to genotoxic stress
- (2020) Sapir Schlam‐Babayov et al. EMBO JOURNAL
- Cellular senescence in ageing: from mechanisms to therapeutic opportunities
- (2020) Raffaella Di Micco et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Cellular proteostasis decline in human senescence
- (2020) Niv Sabath et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Impaired endoplasmic reticulum-mitochondrial signaling in ataxia-telangiectasia
- (2020) Abrey J. Yeo et al. iScience
- ATM is activated by ATP depletion and modulates mitochondrial function through NRF1
- (2019) Hei-Man Chow et al. JOURNAL OF CELL BIOLOGY
- The proteostasis network and its decline in ageing
- (2019) Mark S. Hipp et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- L1 drives IFN in senescent cells and promotes age-associated inflammation
- (2019) Marco De Cecco et al. NATURE
- Epigenetic changes during aging and their reprogramming potential
- (2019) Alice E. Kane et al. CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Acetylation Blocks cGAS Activity and Inhibits Self-DNA-Induced Autoimmunity
- (2019) Jiang Dai et al. CELL
- Extranuclear DNA accumulates in aged cells and contributes to senescence and inflammation
- (2019) Yuk Yuen Lan et al. AGING CELL
- Cellular senescence causes ageing
- (2019) Jesús Gil NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Cellular Senescence: Aging, Cancer, and Injury
- (2019) Arianna Calcinotto et al. PHYSIOLOGICAL REVIEWS
- Accumulation of cytoplasmic DNA due to ATM deficiency activates the microglial viral response system with neurotoxic consequences
- (2019) Xuan Song et al. JOURNAL OF NEUROSCIENCE
- Aging of spermatogonial stem cells by Jnk-mediated glycolysis activation
- (2019) Mito Kanatsu-Shinohara et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Defining Adult Stem Cell Function at Its Simplest: The Ability to Replace Lost Cells through Mitosis
- (2019) Yorick Post et al. Cell Stem Cell
- Chromosome instability syndromes
- (2019) A. Malcolm R. Taylor et al. Nature Reviews Disease Primers
- Cellular Senescence: Defining a Path Forward
- (2019) Vassilis Gorgoulis et al. CELL
- ATM controls DNA repair and mitochondria transfer between neighboring cells
- (2019) Sha Jin et al. Cell Communication and Signaling
- Inhibition of DNA damage response at telomeres improves the detrimental phenotypes of Hutchinson–Gilford Progeria Syndrome
- (2019) Julio Aguado et al. Nature Communications
- Mechanistic understanding of cellular responses to genomic stress
- (2019) Philip Hanawalt et al. ENVIRONMENTAL AND MOLECULAR MUTAGENESIS
- Therapeutic Potential of NAD-Boosting Molecules: The In Vivo Evidence
- (2018) Luis Rajman et al. Cell Metabolism
- Whole-genome sequencing reveals principles of brain retrotransposition in neurodevelopmental disorders
- (2018) Jasmine Jacob-Hirsch et al. CELL RESEARCH
- From “Cellular” RNA to “Smart” RNA: Multiple Roles of RNA in Genome Stability and Beyond
- (2018) Flavia Michelini et al. CHEMICAL REVIEWS
- The response to DNA damage in heterochromatin domains
- (2018) Anna Fortuny et al. CHROMOSOMA
- Target-enrichment sequencing for detailed characterization of small RNAs
- (2018) Quan Nguyen et al. Nature Protocols
- DNA methylation-based biomarkers and the epigenetic clock theory of ageing
- (2018) Steve Horvath et al. NATURE REVIEWS GENETICS
- Cellular and epigenetic drivers of stem cell ageing
- (2018) Maria Ermolaeva et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Mitochondrial redox sensing by the kinase ATM maintains cellular antioxidant capacity
- (2018) Yichong Zhang et al. Science Signaling
- ATM directs DNA damage responses and proteostasis via genetically separable pathways
- (2018) Ji-Hoon Lee et al. Science Signaling
- Hallmarks of Cellular Senescence
- (2018) Alejandra Hernandez-Segura et al. TRENDS IN CELL BIOLOGY
- Aging and the rise of somatic cancer-associated mutations in normal tissues
- (2018) Rosa Ana Risques et al. PLoS Genetics
- Mitochondrial redox sensing by the kinase ATM maintains cellular antioxidant capacity
- (2018) Yichong Zhang et al. Science Signaling
- ATM directs DNA damage responses and proteostasis via genetically separable pathways
- (2018) Ji-Hoon Lee et al. Science Signaling
- Ataxia-Telangiectasia Mutated Kinase in the Control of Oxidative Stress, Mitochondria, and Autophagy in Cancer: A Maestro With a Large Orchestra
- (2018) Venturina Stagni et al. Frontiers in Oncology
- Targeting STING with covalent small-molecule inhibitors
- (2018) Simone M. Haag et al. NATURE
- Inflammaging: a new immune–metabolic viewpoint for age-related diseases
- (2018) Claudio Franceschi et al. Nature Reviews Endocrinology
- Carcinogens and DNA damage
- (2018) Jessica L. Barnes et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Inactive Atm abrogates DSB repair in mouse cerebellum more than does Atm loss, without causing a neurological phenotype
- (2018) Efrat Tal et al. DNA REPAIR
- Ibuprofen prevents progression of ataxia telangiectasia symptoms in ATM-deficient mice
- (2018) Chin Wai Hui et al. Journal of Neuroinflammation
- Inflammation and transcriptional responses of peripheral blood mononuclear cells in classic ataxia telangiectasia
- (2018) Sharon A. McGrath-Morrow et al. PLoS One
- Mechanisms of DNA damage, repair, and mutagenesis
- (2017) Nimrat Chatterjee et al. ENVIRONMENTAL AND MOLECULAR MUTAGENESIS
- The predictive role of heat shock protein 27–60 levels in pediatric patients with ataxia telangiectasia
- (2017) A.A. Ozcelik et al. EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY
- PARPs and ADP-ribosylation: recent advances linking molecular functions to biological outcomes
- (2017) Rebecca Gupte et al. GENES & DEVELOPMENT
- Pathways of cellular proteostasis in aging and disease
- (2017) Courtney L. Klaips et al. JOURNAL OF CELL BIOLOGY
- Cytoplasmic chromatin triggers inflammation in senescence and cancer
- (2017) Zhixun Dou et al. NATURE
- Innate immune sensing of cytosolic chromatin fragments through cGAS promotes senescence
- (2017) Selene Glück et al. NATURE CELL BIOLOGY
- Chemical screening identifies ATM as a target for alleviating senescence
- (2017) Hyun Tae Kang et al. Nature Chemical Biology
- Modulation of proteostasis counteracts oxidative stress and affects DNA base excision repair capacity in ATM-deficient cells
- (2017) Mattia Poletto et al. NUCLEIC ACIDS RESEARCH
- ATM-dependent pathways of chromatin remodelling and oxidative DNA damage responses
- (2017) N. Daniel Berger et al. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- cGAS is essential for cellular senescence
- (2017) Hui Yang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Human iPSC-Derived Cerebellar Neurons from a Patient with Ataxia-Telangiectasia Reveal Disrupted Gene Regulatory Networks
- (2017) Sam P. Nayler et al. Frontiers in Cellular Neuroscience
- DNA damage response inhibition at dysfunctional telomeres by modulation of telomeric DNA damage response RNAs
- (2017) Francesca Rossiello et al. Nature Communications
- A null mutation in SERPINE1 protects against biological aging in humans
- (2017) Sadiya S. Khan et al. Science Advances
- Mechanisms of non-canonical activation of ataxia telangiectasia mutated
- (2016) S. V. Khoronenkova BIOCHEMISTRY-MOSCOW
- Epigenetic Mechanisms of Longevity and Aging
- (2016) Payel Sen et al. CELL
- NAD + Replenishment Improves Lifespan and Healthspan in Ataxia Telangiectasia Models via Mitophagy and DNA Repair
- (2016) Evandro Fei Fang et al. Cell Metabolism
- Loss of the DNA Damage Repair Kinase ATM Impairs Inflammasome-Dependent Anti-Bacterial Innate Immunity
- (2016) Saskia F. Erttmann et al. IMMUNITY
- The DNA Structure-Specific Endonuclease MUS81 Mediates DNA Sensor STING-Dependent Host Rejection of Prostate Cancer Cells
- (2016) Samantha S.W. Ho et al. IMMUNITY
- The Mitochondrial Basis of Aging
- (2016) Nuo Sun et al. MOLECULAR CELL
- Naturally occurring p16Ink4a-positive cells shorten healthy lifespan
- (2016) Darren J. Baker et al. NATURE
- Ataxia telangiectasia: a review
- (2016) Cynthia Rothblum-Oviatt et al. Orphanet Journal of Rare Diseases
- Endocrine abnormalities in ataxia telangiectasia: findings from a national cohort
- (2016) Andreea Nissenkorn et al. PEDIATRIC RESEARCH
- Systemic DNA damage responses in aging and diseases
- (2016) Flavia Ribezzo et al. SEMINARS IN CANCER BIOLOGY
- NADPH: new oxygen for the ROS theory of aging
- (2016) Pablo J. Fernandez-Marcos et al. Oncotarget
- Age-Associated Decrease of the Histone Methyltransferase SUV39H1 in HSC Perturbs Heterochromatin and B Lymphoid Differentiation
- (2016) Dounia Djeghloul et al. Stem Cell Reports
- ATM mediates spermidine-induced mitophagy via PINK1 and Parkin regulation in human fibroblasts
- (2016) Yongmei Qi et al. Scientific Reports
- The Biology of Proteostasis in Aging and Disease
- (2015) Johnathan Labbadia et al. Annual Review of Biochemistry
- Mechanisms of ATM Activation
- (2015) Tanya T. Paull Annual Review of Biochemistry
- The DNA Damage Response: Implications for Tumor Responses to Radiation and Chemotherapy
- (2015) Michael Goldstein et al. Annual Review of Medicine
- Alteration in 5-hydroxymethylcytosine-mediated epigenetic regulation leads to Purkinje cell vulnerability in ATM deficiency
- (2015) Dewei Jiang et al. BRAIN
- Oxidized ATM promotes abnormal proliferation of breast CAFs through maintaining intracellular redox homeostasis and activating the PI3K-AKT, MEK-ERK, and Wnt-β-catenin signaling pathways
- (2015) Shifu Tang et al. CELL CYCLE
- Aging-Induced Stem Cell Mutations as Drivers for Disease and Cancer
- (2015) Peter D. Adams et al. Cell Stem Cell
- DNA Damage Primes the Type I Interferon System via the Cytosolic DNA Sensor STING to Promote Anti-Microbial Innate Immunity
- (2015) Anetta Härtlova et al. IMMUNITY
- Incidence, Presentation, and Prognosis of Malignancies in Ataxia-Telangiectasia: A Report From the French National Registry of Primary Immune Deficiencies
- (2015) Felipe Suarez et al. JOURNAL OF CLINICAL ONCOLOGY
- Reactive Oxygen Species (ROS)-Activated ATM-Dependent Phosphorylation of Cytoplasmic Substrates Identified by Large-Scale Phosphoproteomics Screen
- (2015) Sergei V. Kozlov et al. MOLECULAR & CELLULAR PROTEOMICS
- Autophagy mediates degradation of nuclear lamina
- (2015) Zhixun Dou et al. NATURE
- Constitutive heterochromatin formation and transcription in mammals
- (2015) Nehmé Saksouk et al. Epigenetics & Chromatin
- ATM and ATR Signaling Regulate the Recruitment of Human Telomerase to Telomeres
- (2015) Adrian S. Tong et al. Cell Reports
- ATM Kinase Is Required for Telomere Elongation in Mouse and Human Cells
- (2015) Stella Suyong Lee et al. Cell Reports
- Age and Cancer Risk
- (2014) Mary C. White et al. AMERICAN JOURNAL OF PREVENTIVE MEDICINE
- Brain glucose metabolism in adults with ataxia-telangiectasia and their asymptomatic relatives
- (2014) Nora D. Volkow et al. BRAIN
- ATM: Expanding roles as a chief guardian of genome stability
- (2014) Yosef Shiloh EXPERIMENTAL CELL RESEARCH
- Growth retardation and growth hormone deficiency in patients with Ataxia telangiectasia
- (2014) Sandra Voss et al. GROWTH FACTORS
- ATM Regulates Insulin-Like Growth Factor 1-Secretory Clusterin (IGF-1-sCLU) Expression that Protects Cells against Senescence
- (2014) Xiuquan Luo et al. PLoS One
- Functional and molecular defects of hiPSC-derived neurons from patients with ATM deficiency
- (2014) L Carlessi et al. Cell Death & Disease
- Inflammation-driven carcinogenesis is mediated through STING
- (2014) Jeonghyun Ahn et al. Nature Communications
- The Hallmarks of Aging
- (2013) Carlos López-Otín et al. CELL
- ATM-deficient human neural stem cells as an in vitro model system to study neurodegeneration
- (2013) Luigi Carlessi et al. DNA REPAIR
- Lysosome-mediated processing of chromatin in senescence
- (2013) Andre Ivanov et al. JOURNAL OF CELL BIOLOGY
- Studying the cerebellar DNA damage response in the tissue culture dish
- (2013) Aya Tzur-Gilat et al. MECHANISMS OF AGEING AND DEVELOPMENT
- The GH/IGF-1 axis in ageing and longevity
- (2013) Riia K. Junnila et al. Nature Reviews Endocrinology
- The ATM protein kinase: regulating the cellular response to genotoxic stress and more
- (2013) Yosef Shiloh et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Differential DNA methylation with age displays both common and dynamic features across human tissues that are influenced by CpG landscape
- (2013) Kenneth Day et al. GENOME BIOLOGY
- DNA methylation age of human tissues and cell types
- (2013) Steve Horvath GENOME BIOLOGY
- Aging, Cellular Senescence, and Cancer
- (2012) Judith Campisi Annual Review of Physiology
- ATM-deficient human fibroblast cells are resistant to low levels of DNA double-strand break induced apoptosis and subsequently undergo drug-induced premature senescence
- (2012) Jun Park et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Oxidative stress induces an ATM-independent senescence pathway through p38 MAPK-mediated lamin B1 accumulation
- (2012) Aurelia Barascu et al. EMBO JOURNAL
- Reducing Mitochondrial ROS Improves Disease-related Pathology in a Mouse Model of Ataxia-telangiectasia
- (2012) Anthony D D'Souza et al. MOLECULAR THERAPY
- Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation
- (2012) Marzia Fumagalli et al. NATURE CELL BIOLOGY
- Nuclear accumulation of HDAC4 in ATM deficiency promotes neurodegeneration in ataxia telangiectasia
- (2012) Jiali Li et al. NATURE MEDICINE
- The telomere syndromes
- (2012) Mary Armanios et al. NATURE REVIEWS GENETICS
- High-order chromatin structure and the epigenome in SAHFs
- (2012) Tamir Chandra et al. Nucleus
- Mitochondrial dysfunction in ataxia-telangiectasia
- (2011) Y. A. Valentin-Vega et al. BLOOD
- ATM activation in the presence of oxidative stress
- (2011) Zhi Guo et al. CELL CYCLE
- Regulation of chromatin by histone modifications
- (2011) Andrew J Bannister et al. CELL RESEARCH
- Beyond ATM: The protein kinase landscape of the DNA damage response
- (2011) Ariel Bensimon et al. FEBS LETTERS
- Investigation of the Functional Link betweenATMandNBS1in the DNA Damage Response in the Mouse Cerebellum
- (2011) Inbal Dar et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Four faces of cellular senescence
- (2011) Francis Rodier et al. JOURNAL OF CELL BIOLOGY
- Role of AMPK-mTOR-Ulk1/2 in the Regulation of Autophagy: Cross Talk, Shortcuts, and Feedbacks
- (2011) S. Alers et al. MOLECULAR AND CELLULAR BIOLOGY
- A Novel Role for ATM in Regulating Proteasome-Mediated Protein Degradation through Suppression of the ISG15 Conjugation Pathway
- (2011) Laurence M. Wood et al. PLoS One
- Ataxia telangiectasia mutated (ATM) modulates long interspersed element-1 (L1) retrotransposition in human neural stem cells
- (2011) N. G. Coufal et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Retrotransposition is associated with genome instability during chronological aging
- (2011) P. H. Maxwell et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression
- (2010) Jean-Philippe Coppé et al. Annual Review of Pathology-Mechanisms of Disease
- ATM engages the TSC2/mTORC1 signaling node to regulate autophagy
- (2010) Angela Alexander et al. Autophagy
- Differential localization of ATM is correlated with activation of distinct downstream signaling pathways
- (2010) Angela Alexander et al. CELL CYCLE
- A Genome-Wide siRNA Screen Reveals Multiple mTORC1 Independent Signaling Pathways Regulating Autophagy under Normal Nutritional Conditions
- (2010) Marta M. Lipinski et al. DEVELOPMENTAL CELL
- ATM activates the pentose phosphate pathway promoting anti-oxidant defence and DNA repair
- (2010) Claudia Cosentino et al. EMBO JOURNAL
- The Secret Life of NAD+: An Old Metabolite Controlling New Metabolic Signaling Pathways
- (2010) Riekelt H. Houtkooper et al. ENDOCRINE REVIEWS
- Telomeres: protecting chromosomes against genome instability
- (2010) Roderick J. O'Sullivan et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Reduced histone biosynthesis and chromatin changes arising from a damage signal at telomeres
- (2010) Roderick J O'Sullivan et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS
- (2010) A. Alexander et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- ATM Activation by Oxidative Stress
- (2010) Z. Guo et al. SCIENCE
- ATM-Dependent and -Independent Dynamics of the Nuclear Phosphoproteome After DNA Damage
- (2010) A. Bensimon et al. Science Signaling
- Sirt1 improves healthy ageing and protects from metabolic syndrome-associated cancer
- (2010) Daniel Herranz et al. Nature Communications
- Oxidative Stress Is Linked to ERK1/2-p16 Signaling-mediated Growth Defect in ATM-deficient Astrocytes
- (2009) Jeesun Kim et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The DNA-damage response in human biology and disease
- (2009) Stephen P. Jackson et al. NATURE
- STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity
- (2009) Hiroki Ishikawa et al. NATURE
- Assessing the role of stress signalling via p38 MAP kinase in the premature senescence of Ataxia Telangiectasia and Werner syndrome fibroblasts
- (2008) Terence Davis et al. BIOGERONTOLOGY
- Stem Cell Defects in ATM-Deficient Undifferentiated Spermatogonia through DNA Damage-Induced Cell-Cycle Arrest
- (2008) Keiyo Takubo et al. Cell Stem Cell
- The neurological phenotype of ataxia-telangiectasia: Solving a persistent puzzle
- (2008) Sharon Biton et al. DNA REPAIR
- Aging by epigenetics—A consequence of chromatin damage?
- (2008) John M. Sedivy et al. EXPERIMENTAL CELL RESEARCH
- STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling
- (2008) Hiroki Ishikawa et al. NATURE
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