DNA damage response inhibition at dysfunctional telomeres by modulation of telomeric DNA damage response RNAs

DNA damage markers in dermal fibroblasts in vitro reflect chronological donor age

(2016) Mariëtte E.C. Waaijer et al.   Aging-US

Transient RNA-DNA Hybrids Are Required for Efficient Double-Strand Break Repair

(2016) Corina Ohle et al.   CELL

DICER, DROSHA and DNA damage response RNAs are necessary for the secondary recruitment of DNA damage response factors

(2016) Sofia Francia et al.   JOURNAL OF CELL SCIENCE

Histone H2AX and the small RNA pathway modulate both non-homologous end-joining and homologous recombination in plants

(2016) Yiping Qi et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Classical non-homologous end-joining pathway utilizes nascent RNA for error-free double-strand break repair of transcribed genes

(2016) Anirban Chakraborty et al.   Nature Communications

An overview of the clinical application of antisense oligonucleotides for RNA-targeting therapies

(2015) Graham McClorey et al.   CURRENT OPINION IN PHARMACOLOGY

Spatiotemporal regulation of posttranslational modifications in the DNA damage response

(2015) N. P. Dantuma et al.   EMBO JOURNAL

Gene-targeting pharmaceuticals for single-gene disorders

(2015) Arthur L. Beaudet et al.   HUMAN MOLECULAR GENETICS

Dgcr8 and Dicer are essential for sex chromosome integrity during meiosis in males

(2015) A. J. Modzelewski et al.   JOURNAL OF CELL SCIENCE

Knocking down disease: a progress report on siRNA therapeutics

(2015) Anders Wittrup et al.   NATURE REVIEWS GENETICS

Non-Coding RNA: Sequence-Specific Guide for Chromatin Modification and DNA Damage Signaling

(2015) Sofia Francia   Frontiers in Genetics

Ago2 facilitates Rad51 recruitment and DNA double-strand break repair by homologous recombination

(2014) Min Gao et al.   CELL RESEARCH

Evaluation of quantitative miRNA expression platforms in the microRNA quality control (miRQC) study

(2014) Pieter Mestdagh et al.   NATURE METHODS

Identification of TERRA locus unveils a telomere protection role through association to nearly all chromosomes

(2014) Isabel López de Silanes et al.   Nature Communications

Functional characterization of the TERRA transcriptome at damaged telomeres

(2014) Antonio Porro et al.   Nature Communications

Non-coding RNAs in DNA damage and repair

(2013) Vivek Sharma et al.   FEBS LETTERS

A two-step mechanism for TRF2-mediated chromosome-end protection

(2013) Keiji Okamoto et al.   NATURE

Double-strand break repair: 53BP1 comes into focus

(2013) Stephanie Panier et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A direct role for small non-coding RNAs in DNA damage response

(2013) Fabrizio d’Adda di Fagagna   TRENDS IN CELL BIOLOGY

A Role for Small RNAs in DNA Double-Strand Break Repair

(2012) Wei Wei et al.   CELL

Oncogene-induced telomere dysfunction enforces cellular senescence in human cancer precursor lesions

(2012) Anitha Suram et al.   EMBO JOURNAL

Intracellular single molecule microscopy reveals two kinetically distinct pathways for microRNA assembly

(2012) Sethuramasundaram Pitchiaya et al.   EMBO REPORTS

Site-specific DICER and DROSHA RNA products control the DNA-damage response

(2012) Sofia Francia et al.   NATURE

Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation

(2012) Marzia Fumagalli et al.   NATURE CELL BIOLOGY

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

The telomere syndromes

(2012) Mary Armanios et al.   NATURE REVIEWS GENETICS

Removal of Shelterin Reveals the Telomere End-Protection Problem

(2012) A. Sfeir et al.   SCIENCE

Telomeres are favoured targets of a persistent DNA damage response in ageing and stress-induced senescence

(2012) Graeme Hewitt et al.   Nature Communications

Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications

(2011) S. E. Polo et al.   GENES & DEVELOPMENT

Non-coding telomeric and subtelomeric transcripts are differentially regulated by telomeric and heterochromatin assembly factors in fission yeast

(2011) Jessica Greenwood et al.   NUCLEIC ACIDS RESEARCH

The telomeric transcriptome of Schizosaccharomyces pombe

(2011) Amadou Bah et al.   NUCLEIC ACIDS RESEARCH

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

How Shelterin Protects Mammalian Telomeres

(2008) Wilhelm Palm et al.   Annual Review of Genetics

ATM Signaling Facilitates Repair of DNA Double-Strand Breaks Associated with Heterochromatin

(2008) Aaron A. Goodarzi et al.   MOLECULAR CELL

Imaging individual mRNA molecules using multiple singly labeled probes

(2008) Arjun Raj et al.   NATURE METHODS