PARPs and ADP-ribosylation: recent advances linking molecular functions to biological outcomes
出版年份 2017 全文链接
标题
PARPs and ADP-ribosylation: recent advances linking molecular functions to biological outcomes
作者
关键词
-
出版物
GENES & DEVELOPMENT
Volume 31, Issue 2, Pages 101-126
出版商
Cold Spring Harbor Laboratory
发表日期
2017-02-15
DOI
10.1101/gad.291518.116
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- PARP-1 Controls the Adipogenic Transcriptional Program by PARylating C/EBPβ and Modulating Its Transcriptional Activity
- (2017) Xin Luo et al. MOLECULAR CELL
- Catalytic-Independent Functions of PARP-1 Determine Sox2 Pioneer Activity at Intractable Genomic Loci
- (2017) Ziying Liu et al. MOLECULAR CELL
- Chemical proteomics reveals ADP-ribosylation of small GTPases during oxidative stress
- (2017) Nathan P Westcott et al. Nature Chemical Biology
- Synthesis and Macrodomain Binding of Mono-ADP-Ribosylated Peptides
- (2016) Hans A. V. Kistemaker et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Macrodomains: Structure, Function, Evolution, and Catalytic Activities
- (2016) Johannes Gregor Matthias Rack et al. Annual Review of Biochemistry
- Phase 2 multicentre trial investigating intermittent and continuous dosing schedules of the poly(ADP-ribose) polymerase inhibitor rucaparib in germline BRCA mutation carriers with advanced ovarian and breast cancer
- (2016) Yvette Drew et al. BRITISH JOURNAL OF CANCER
- PARP inhibitors: the race is on
- (2016) Jessica S Brown et al. BRITISH JOURNAL OF CANCER
- Leveraging an NQO1 Bioactivatable Drug for Tumor-Selective Use of Poly(ADP-ribose) Polymerase Inhibitors
- (2016) Xiumei Huang et al. CANCER CELL
- ENPP1 processes protein ADP-ribosylationin vitro
- (2016) Luca Palazzo et al. FEBS Journal
- Structural Basis for Potency and Promiscuity in Poly(ADP-ribose) Polymerase (PARP) and Tankyrase Inhibitors
- (2016) Ann-Gerd Thorsell et al. JOURNAL OF MEDICINAL CHEMISTRY
- Viral Macro Domains Reverse Protein ADP-Ribosylation
- (2016) Changqing Li et al. JOURNAL OF VIROLOGY
- PARP1 Links CHD2-Mediated Chromatin Expansion and H3.3 Deposition to DNA Repair by Non-homologous End-Joining
- (2016) Martijn S. Luijsterburg et al. MOLECULAR CELL
- The Toxin-Antitoxin System DarTG Catalyzes Reversible ADP-Ribosylation of DNA
- (2016) Gytis Jankevicius et al. MOLECULAR CELL
- Analysis of Chromatin ADP-Ribosylation at the Genome-wide Level and at Specific Loci by ADPr-ChAP
- (2016) Giody Bartolomei et al. MOLECULAR CELL
- HPF1/C4orf27 Is a PARP-1-Interacting Protein that Regulates PARP-1 ADP-Ribosylation Activity
- (2016) Ian Gibbs-Seymour et al. MOLECULAR CELL
- Ubiquitination independent of E1 and E2 enzymes by bacterial effectors
- (2016) Jiazhang Qiu et al. NATURE
- Serine is a new target residue for endogenous ADP-ribosylation on histones
- (2016) Orsolya Leidecker et al. Nature Chemical Biology
- Fluorescent sensors of PARP-1 structural dynamics and allosteric regulation in response to DNA damage
- (2016) Jamin D. Steffen et al. NUCLEIC ACIDS RESEARCH
- ADP-ribose–derived nuclear ATP synthesis by NUDIX5 is required for chromatin remodeling
- (2016) Roni H. G. Wright et al. SCIENCE
- Biosensor reveals multiple sources for mitochondrial NAD+
- (2016) X. A. Cambronne et al. SCIENCE
- A nuclease that mediates cell death induced by DNA damage and poly(ADP-ribose) polymerase-1
- (2016) Y. Wang et al. SCIENCE
- Chemical genetic discovery of PARP targets reveals a role for PARP-1 in transcription elongation
- (2016) B. A. Gibson et al. SCIENCE
- PARP9 and PARP14 cross-regulate macrophage activation via STAT1 ADP-ribosylation
- (2016) Hiroshi Iwata et al. Nature Communications
- PARP3 is a sensor of nicked nucleosomes and monoribosylates histone H2BGlu2
- (2016) Gabrielle J. Grundy et al. Nature Communications
- Proteome-wide identification of the endogenous ADP-ribosylome of mammalian cells and tissue
- (2016) Rita Martello et al. Nature Communications
- PARP6 is a Regulator of Hippocampal Dendritic Morphogenesis
- (2016) Jeffrey Y. Huang et al. Scientific Reports
- Identifying Family-Member-Specific Targets of Mono-ARTDs by Using a Chemical Genetics Approach
- (2016) Ian Carter-O’Connell et al. Cell Reports
- Virus–Host Interactions and the ARTD/PARP Family of Enzymes
- (2016) Chad V. Kuny et al. PLoS Pathogens
- Activation of the PI3K/mTOR Pathway following PARP Inhibition in Small Cell Lung Cancer
- (2016) Robert J. Cardnell et al. PLoS One
- Processing of protein ADP-ribosylation by Nudix hydrolases
- (2015) Luca Palazzo et al. BIOCHEMICAL JOURNAL
- No Driver behind the Wheel? Targeting Transcription in Cancer
- (2015) Hector L. Franco et al. CELL
- CDK7-Dependent Transcriptional Addiction in Triple-Negative Breast Cancer
- (2015) Yubao Wang et al. CELL
- New Facets in the Regulation of Gene Expression by ADP-Ribosylation and Poly(ADP-ribose) Polymerases
- (2015) Keun Woo Ryu et al. CHEMICAL REVIEWS
- Quantitative site-specific ADP-ribosylation profiling of DNA-dependent PARPs
- (2015) Jean-Philippe Gagné et al. DNA REPAIR
- Optimization of LTQ-Orbitrap Mass Spectrometer Parameters for the Identification of ADP-Ribosylation Sites
- (2015) Florian Rosenthal et al. JOURNAL OF PROTEOME RESEARCH
- SnapShot: ADP-Ribosylation Signaling
- (2015) Michael O. Hottiger MOLECULAR CELL
- PARP1- and CTCF-Mediated Interactions between Active and Repressed Chromatin at the Lamina Promote Oscillating Transcription
- (2015) Honglei Zhao et al. MOLECULAR CELL
- The Promise of Proteomics for the Study of ADP-Ribosylation
- (2015) Casey M. Daniels et al. MOLECULAR CELL
- Structural Basis of Detection and Signaling of DNA Single-Strand Breaks by Human PARP-1
- (2015) Sebastian Eustermann et al. MOLECULAR CELL
- PARP-1 Activation Requires Local Unfolding of an Autoinhibitory Domain
- (2015) Jennine M. Dawicki-McKenna et al. MOLECULAR CELL
- PARP9-DTX3L ubiquitin ligase targets host histone H2BJ and viral 3C protease to enhance interferon signaling and control viral infection
- (2015) Yong Zhang et al. NATURE IMMUNOLOGY
- DNA-Repair Defects and Olaparib in Metastatic Prostate Cancer
- (2015) Joaquin Mateo et al. NEW ENGLAND JOURNAL OF MEDICINE
- PARP-2 domain requirements for DNA damage-dependent activation and localization to sites of DNA damage
- (2015) Amanda A. Riccio et al. NUCLEIC ACIDS RESEARCH
- Readers of poly(ADP-ribose): designed to be fit for purpose
- (2015) Federico Teloni et al. NUCLEIC ACIDS RESEARCH
- Liquid demixing of intrinsically disordered proteins is seeded by poly(ADP-ribose)
- (2015) Matthias Altmeyer et al. Nature Communications
- The Zinc-Finger Antiviral Protein ZAP Inhibits LINE and Alu Retrotransposition
- (2015) John B. Moldovan et al. PLoS Genetics
- The Broad-Spectrum Antiviral Protein ZAP Restricts Human Retrotransposition
- (2015) John L. Goodier et al. PLoS Genetics
- Poly(ADP-ribose) polymerases in double-strand break repair: Focus on PARP1, PARP2 and PARP3
- (2014) Carole Beck et al. EXPERIMENTAL CELL RESEARCH
- PARP12, an Interferon-stimulated Gene Involved in the Control of Protein Translation and Inflammation
- (2014) Iain Welsby et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Phosphoproteomic Approach to Characterize Protein Mono- and Poly(ADP-ribosyl)ation Sites from Cells
- (2014) Casey M. Daniels et al. JOURNAL OF PROTEOME RESEARCH
- Engineering the Substrate Specificity of ADP-Ribosyltransferases for Identifying Direct Protein Targets
- (2014) Ian Carter-O’Connell et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- The Histone Variant MacroH2A1 Regulates Target Gene Expression in Part by Recruiting the Transcriptional Coregulator PELP1
- (2014) K. M. Hussey et al. MOLECULAR AND CELLULAR BIOLOGY
- PARP3 affects the relative contribution of homologous recombination and nonhomologous end-joining pathways
- (2014) Carole Beck et al. NUCLEIC ACIDS RESEARCH
- PARP-2 and PARP-3 are selectively activated by 5′ phosphorylated DNA breaks through an allosteric regulatory mechanism shared with PARP-1
- (2014) Marie-France Langelier et al. NUCLEIC ACIDS RESEARCH
- Automodification switches PARP-1 function from chromatin architectural protein to histone chaperone
- (2014) U. M. Muthurajan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Family-wide analysis of poly(ADP-ribose) polymerase activity
- (2014) Sejal Vyas et al. Nature Communications
- PARP13 regulates cellular mRNA post-transcriptionally and functions as a pro-apoptotic factor by destabilizing TRAILR4 transcript
- (2014) Tanya Todorova et al. Nature Communications
- Rapid Evolution of PARP Genes Suggests a Broad Role for ADP-Ribosylation in Host-Virus Conflicts
- (2014) Matthew D. Daugherty et al. PLoS Genetics
- Targeting PARP-1 Allosteric Regulation Offers Therapeutic Potential against Cancer
- (2013) J. D. Steffen et al. CANCER RESEARCH
- Poly(ADP-ribosyl)ation Regulates Insulator Function and Intrachromosomal Interactions in Drosophila
- (2013) Chin-Tong Ong et al. CELL
- What Pathogens Have Taught Us About Posttranslational Modifications
- (2013) Dor Salomon et al. Cell Host & Microbe
- Reciprocal Inhibition between Intracellular Antiviral Signaling and the RNAi Machinery in Mammalian Cells
- (2013) Gil Ju Seo et al. Cell Host & Microbe
- Proteomic Markers of DNA Repair and PI3K Pathway Activation Predict Response to the PARP Inhibitor BMN 673 in Small Cell Lung Cancer
- (2013) R. J. Cardnell et al. CLINICAL CANCER RESEARCH
- Deficiency of terminal ADP-ribose protein glycohydrolase TARG1/C6orf130 in neurodegenerative disease
- (2013) Reza Sharifi et al. EMBO JOURNAL
- The recognition and removal of cellular poly(ADP-ribose) signals
- (2013) Eva Barkauskaite et al. FEBS Journal
- The FHA and BRCT domains recognize ADP-ribosylation during DNA damage response
- (2013) M. Li et al. GENES & DEVELOPMENT
- B Cell-Intrinsic and -Extrinsic Regulation of Antibody Responses by PARP14, an Intracellular (ADP-Ribosyl)Transferase
- (2013) S. H. Cho et al. JOURNAL OF IMMUNOLOGY
- Mapping PARP-1 Auto-ADP-ribosylation Sites by Liquid Chromatography–Tandem Mass Spectrometry
- (2013) John D Chapman et al. JOURNAL OF PROTEOME RESEARCH
- Therapeutic applications of PARP inhibitors: Anticancer therapy and beyond
- (2013) Nicola J. Curtin et al. MOLECULAR ASPECTS OF MEDICINE
- Structural biology of the writers, readers, and erasers in mono- and poly(ADP-ribose) mediated signaling
- (2013) Tobias Karlberg et al. MOLECULAR ASPECTS OF MEDICINE
- Proteome-wide Identification of Poly(ADP-Ribosyl)ation Targets in Different Genotoxic Stress Responses
- (2013) Stephanie Jungmichel et al. MOLECULAR CELL
- Site-specific characterization of the Asp- and Glu-ADP-ribosylated proteome
- (2013) Yajie Zhang et al. NATURE METHODS
- Macrodomain-containing proteins: regulating new intracellular functions of mono(ADP-ribosyl)ation
- (2013) Karla L. H. Feijs et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Macrodomain-containing proteins are new mono-ADP-ribosylhydrolases
- (2013) Florian Rosenthal et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- A family of macrodomain proteins reverses cellular mono-ADP-ribosylation
- (2013) Gytis Jankevicius et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- The PARP3- and ATM-dependent phosphorylation of APLF facilitates DNA double-strand break repair
- (2013) Amanda L. Fenton et al. NUCLEIC ACIDS RESEARCH
- Stereoselective Ribosylation of Amino Acids
- (2013) Hans A. V. Kistemaker et al. ORGANIC LETTERS
- Monitoring Drug Target Engagement in Cells and Tissues Using the Cellular Thermal Shift Assay
- (2013) D. M. Molina et al. SCIENCE
- Evaluation and Structural Basis for the Inhibition of Tankyrases by PARP Inhibitors
- (2013) Teemu Haikarainen et al. ACS Medicinal Chemistry Letters
- Regulation of NF-κB signalling by the mono-ADP-ribosyltransferase ARTD10
- (2013) Patricia Verheugd et al. Nature Communications
- A systematic analysis of the PARP protein family identifies new functions critical for cell physiology
- (2013) Sejal Vyas et al. Nature Communications
- Rules of Engagement: Molecular Insights from Host-Virus Arms Races
- (2012) Matthew D. Daugherty et al. Annual Review of Genetics
- The diverse roles and clinical relevance of PARPs in DNA damage repair: Current state of the art
- (2012) Mike De Vos et al. BIOCHEMICAL PHARMACOLOGY
- Recognition of the iso-ADP-ribose moiety in poly(ADP-ribose) by WWE domains suggests a general mechanism for poly(ADP-ribosyl)ation-dependent ubiquitination
- (2012) Z. Wang et al. GENES & DEVELOPMENT
- On PAR with PARP: cellular stress signaling through poly(ADP-ribose) and PARP-1
- (2012) X. Luo et al. GENES & DEVELOPMENT
- Regulation of Poly(ADP-ribose) Polymerase-1-dependent Gene Expression through Promoter-directed Recruitment of a Nuclear NAD+Synthase
- (2012) Tong Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- CHFR Protein Regulates Mitotic Checkpoint by Targeting PARP-1 Protein for Ubiquitination and Degradation
- (2012) Lisa Kashima et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- ADP-ribosylhydrolase 3 (ARH3), Not Poly(ADP-ribose) Glycohydrolase (PARG) Isoforms, Is Responsible for Degradation of Mitochondrial Matrix-associated Poly(ADP-ribose)
- (2012) Marc Niere et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Herpes Simplex Virus 1 Infection Activates Poly(ADP-Ribose) Polymerase and Triggers the Degradation of Poly(ADP-Ribose) Glycohydrolase
- (2012) S. L. Grady et al. JOURNAL OF VIROLOGY
- Histone ADP-Ribosylation Facilitates Gene Transcription by Directly Remodeling Nucleosomes
- (2012) R. Martinez-Zamudio et al. MOLECULAR AND CELLULAR BIOLOGY
- Reprogramming cellular events by poly(ADP-ribose)-binding proteins
- (2012) Jana Krietsch et al. MOLECULAR ASPECTS OF MEDICINE
- Inheritance of Silent rDNA Chromatin Is Mediated by PARP1 via Noncoding RNA
- (2012) Claudio Guetg et al. MOLECULAR CELL
- Family-wide chemical profiling and structural analysis of PARP and tankyrase inhibitors
- (2012) Elisabet Wahlberg et al. NATURE BIOTECHNOLOGY
- PARP16 is a tail-anchored endoplasmic reticulum protein required for the PERK- and IRE1α-mediated unfolded protein response
- (2012) Miri Jwa et al. NATURE CELL BIOLOGY
- Promoter-proximal pausing of RNA polymerase II: emerging roles in metazoans
- (2012) Karen Adelman et al. NATURE REVIEWS GENETICS
- New insights into the molecular and cellular functions of poly(ADP-ribose) and PARPs
- (2012) Bryan A. Gibson et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Poly(ADP-ribose) polymerase family member 14 (PARP14) is a novel effector of the JNK2-dependent pro-survival signal in multiple myeloma
- (2012) A Barbarulo et al. ONCOGENE
- Beyond Oil and Water--Phase Transitions in Cells
- (2012) A. A. Hyman et al. SCIENCE
- Structural Basis for DNA Damage-Dependent Poly(ADP-ribosyl)ation by Human PARP-1
- (2012) M.-F. Langelier et al. SCIENCE
- New readers and interpretations of poly(ADP-ribosyl)ation
- (2012) Thomas Kalisch et al. TRENDS IN BIOCHEMICAL SCIENCES
- Proteomic Profiling Identifies Dysregulated Pathways in Small Cell Lung Cancer and Novel Therapeutic Targets Including PARP1
- (2012) Lauren Averett Byers et al. Cancer Discovery
- Dual Roles of PARP-1 Promote Cancer Growth and Progression
- (2012) M. J. Schiewer et al. Cancer Discovery
- Poly(ADP-Ribose) Polymerase 1 (PARP-1) Regulates Ribosomal Biogenesis in Drosophila Nucleoli
- (2012) Ernest K. Boamah et al. PLoS Genetics
- Imaging Cytosolic NADH-NAD+ Redox State with a Genetically Encoded Fluorescent Biosensor
- (2011) Yin Pun Hung et al. Cell Metabolism
- Crystal Structures of Poly(ADP-ribose) Polymerase-1 (PARP-1) Zinc Fingers Bound to DNA
- (2011) Marie-France Langelier et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- PARP-3 and APLF Function Together to Accelerate Nonhomologous End-Joining
- (2011) Stuart L. Rulten et al. MOLECULAR CELL
- Poly(ADP-Ribose) Regulates Stress Responses and MicroRNA Activity in the Cytoplasm
- (2011) Anthony K.L. Leung et al. MOLECULAR CELL
- The structure and catalytic mechanism of a poly(ADP-ribose) glycohydrolase
- (2011) Dea Slade et al. NATURE
- RNF146 is a poly(ADP-ribose)-directed E3 ligase that regulates axin degradation and Wnt signalling
- (2011) Yue Zhang et al. NATURE CELL BIOLOGY
- A Key Role for Poly(ADP-Ribose) Polymerase 3 in Ectodermal Specification and Neural Crest Development
- (2011) Michèle Rouleau et al. PLoS One
- Glycolytic rate and lymphomagenesis depend on PARP14, an ADP ribosyltransferase of the B aggressive lymphoma (BAL) family
- (2011) S. H. Cho et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Iduna is a poly(ADP-ribose) (PAR)-dependent E3 ubiquitin ligase that regulates DNA damage
- (2011) H. C. Kang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Poly(ADP-ribose) polymerase 3 (PARP3), a newcomer in cellular response to DNA damage and mitotic progression
- (2011) C. Boehler et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Stress-Induced PARP Activation Mediates Recruitment of Drosophila Mi-2 to Promote Heat Shock Gene Expression
- (2011) Magdalena Murawska et al. PLoS Genetics
- Mammalian Sirtuins: Biological Insights and Disease Relevance
- (2010) Marcia C. Haigis et al. Annual Review of Pathology-Mechanisms of Disease
- Function and metabolism of sirtuin metabolite O-acetyl-ADP-ribose
- (2010) Lei Tong et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- The Zn3 Domain of Human Poly(ADP-ribose) Polymerase-1 (PARP-1) Functions in Both DNA-dependent Poly(ADP-ribose) Synthesis Activity and Chromatin Compaction
- (2010) Marie-France Langelier et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Epigenetic modulation of host: new insights into immune evasion by viruses
- (2010) Dwaipayan Adhya et al. JOURNAL OF BIOSCIENCES
- Synthesis of Mono-ADP-Ribosylated Oligopeptides Using Ribosylated Amino Acid Building Blocks
- (2010) Gerbrand J. van der Heden van Noort et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Method for the Synthesis of Mono-ADP-ribose Conjugated Peptides
- (2010) Peter M. Moyle et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- The PARP Side of the Nucleus: Molecular Actions, Physiological Outcomes, and Clinical Targets
- (2010) Raga Krishnakumar et al. MOLECULAR CELL
- PARP-1 Regulates Chromatin Structure and Transcription through a KDM5B-Dependent Pathway
- (2010) Raga Krishnakumar et al. MOLECULAR CELL
- PARP1 ADP-ribosylates lysine residues of the core histone tails
- (2010) Simon Messner et al. NUCLEIC ACIDS RESEARCH
- A chromatin localization screen reveals poly (ADP ribose)-regulated recruitment of the repressive polycomb and NuRD complexes to sites of DNA damage
- (2010) D. M. Chou et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structure and identification of ADP-ribose recognition motifs of APLF and role in the DNA damage response
- (2010) G.-Y. Li et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Toward a unified nomenclature for mammalian ADP-ribosyltransferases
- (2010) Michael O. Hottiger et al. TRENDS IN BIOCHEMICAL SCIENCES
- The Potential of PARP Inhibitors in Genetic Breast and Ovarian Cancers
- (2009) Yvette Drew et al. Annals of the New York Academy of Sciences
- Functional interplay between Parp-1 and SirT1 in genome integrity and chromatin-based processes
- (2009) Rosy El Ramy et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- PARP1 Poly(ADP-ribosyl)ates Sox2 to Control Sox2 Protein Levels andFGF4Expression during Embryonic Stem Cell Differentiation
- (2009) Furong Gao et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Enzymes in the NAD+Salvage Pathway Regulate SIRT1 Activity at Target Gene Promoters
- (2009) Tong Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Characterization ofStreptococcus pyogenesβ-NAD+Glycohydrolase
- (2009) Joydeep Ghosh et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structural Basis for Inhibitor Specificity in Human Poly(ADP-ribose) Polymerase-3†
- (2009) Lari Lehtiö et al. JOURNAL OF MEDICINAL CHEMISTRY
- The Crystal Structures of Chikungunya and Venezuelan Equine Encephalitis Virus nsP3 Macro Domains Define a Conserved Adenosine Binding Pocket
- (2009) H. Malet et al. JOURNAL OF VIROLOGY
- Mutational Analysis of the Poly(ADP-Ribosyl)ation Sites of the Transcription Factor CTCF Provides an Insight into the Mechanism of Its Regulation by Poly(ADP-Ribosyl)ation
- (2009) D. Farrar et al. MOLECULAR AND CELLULAR BIOLOGY
- SIRT1 Promotes Cell Survival under Stress by Deacetylation-Dependent Deactivation of Poly(ADP-Ribose) Polymerase 1
- (2009) S. B. Rajamohan et al. MOLECULAR AND CELLULAR BIOLOGY
- The emerging role of nuclear architecture in DNA repair and genome maintenance
- (2009) Tom Misteli et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- A macrodomain-containing histone rearranges chromatin upon sensing PARP1 activation
- (2009) Gyula Timinszky et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Inhibition of Poly(ADP-Ribose) Polymerase in Tumors fromBRCAMutation Carriers
- (2009) Peter C. Fong et al. NEW ENGLAND JOURNAL OF MEDICINE
- Poly(ADP-ribosyl)ation directs recruitment and activation of an ATP-dependent chromatin remodeler
- (2009) A. J. Gottschalk et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Poly(ADP-ribose)-Dependent Regulation of DNA Repair by the Chromatin Remodeling Enzyme ALC1
- (2009) D. Ahel et al. SCIENCE
- Rapid, Transcription-Independent Loss of Nucleosomes over a Large Chromatin Domain at Hsp70 Loci
- (2008) Steven J. Petesch et al. CELL
- Protein Arginine Methyltransferase 1 Coactivates NF-κB-Dependent Gene Expression Synergistically with CARM1 and PARP1
- (2008) Paul O. Hassa et al. JOURNAL OF MOLECULAR BIOLOGY
- Regulation of Transcription Factor NFAT by ADP-Ribosylation
- (2008) O. A. Olabisi et al. MOLECULAR AND CELLULAR BIOLOGY
- Poly(ADP-ribose)-binding zinc finger motifs in DNA repair/checkpoint proteins
- (2008) Ivan Ahel et al. NATURE
- Proteome-wide identification of poly(ADP-ribose) binding proteins and poly(ADP-ribose)-associated protein complexes
- (2008) Jean-Philippe Gagné et al. NUCLEIC ACIDS RESEARCH
- Reciprocal Binding of PARP-1 and Histone H1 at Promoters Specifies Transcriptional Outcomes
- (2008) R. Krishnakumar et al. SCIENCE
- The Nucleosome-Remodeling ATPase ISWI Is Regulated by Poly-ADP-Ribosylation
- (2008) Anna Sala et al. PLOS BIOLOGY
- NAD+/NADH and NADP+/NADPH in Cellular Functions and Cell Death: Regulation and Biological Consequences
- (2007) Weihai Ying ANTIOXIDANTS & REDOX SIGNALING
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