Inhibition of DNA damage response at telomeres improves the detrimental phenotypes of Hutchinson–Gilford Progeria Syndrome

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A practical qPCR approach to detect TERRA, the elusive telomeric repeat-containing RNA

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Damage-induced lncRNAs control the DNA damage response through interaction with DDRNAs at individual double-strand breaks

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Progerin reduces LAP2α-telomere association in Hutchinson-Gilford progeria

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Irreparable telomeric DNA damage and persistent DDR signalling as a shared causative mechanism of cellular senescence and ageing

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Embryonic expression of the common progeroid lamin A splice mutation arrests postnatal skin development

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A direct role for small non-coding RNAs in DNA damage response

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Site-specific DICER and DROSHA RNA products control the DNA-damage response

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Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation

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Stem cell depletion in Hutchinson-Gilford progeria syndrome

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Cardiovascular Pathology in Hutchinson-Gilford Progeria: Correlation With the Vascular Pathology of Aging

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Role of progerin-induced telomere dysfunction in HGPS premature cellular senescence

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Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice

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Increased expression of the Hutchinson–Gilford progeria syndrome truncated lamin A transcript during cell aging

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Telomere length in Hutchinson-Gilford Progeria Syndrome

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Targeted transgenic expression of the mutation causing Hutchinson-Gilford progeria syndrome leads to proliferative and degenerative epidermal disease

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Suppression of Proliferative Defects Associated with Processing-defective Lamin A Mutants by hTERT or Inactivation of p53

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Lamin A-dependent misregulation of adult stem cells associated with accelerated ageing

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Phenotype and Course of Hutchinson–Gilford Progeria Syndrome

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