Sirt1 improves healthy ageing and protects from metabolic syndrome-associated cancer

SIRT1, Is It a Tumor Promoter or Tumor Suppressor?

(2012) Chu-Xia Deng   International Journal of Biological Sciences

SRT1720, SRT2183, SRT1460, and Resveratrol Are Not Direct Activators of SIRT1

(2010) Michelle Pacholec et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Deleted in breast cancer–1 regulates SIRT1 activity and contributes to high-fat diet–induced liver steatosis in mice

(2010) Carlos Escande et al.   JOURNAL OF CLINICAL INVESTIGATION

The impact of acute caloric restriction on the metabolic phenotype in male C57BL/6 and DBA/2 mice

(2010) Sarah Hempenstall et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Lifespan extension in genetically modified mice

(2009) Warren Ladiges et al.   AGING CELL

Resveratrol is Not a Direct Activator of SIRT1 Enzyme Activity

(2009) Dirk Beher et al.   Chemical Biology & Drug Design

A comprehensive definition for metabolic syndrome

(2009) P. L. Huang   Disease Models & Mechanisms

Sirtuin activators

(2009) Francisco J Alcaín et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

(2009) Carles Cantó et al.   NATURE

Inhibition of osteoblastic bone formation by nuclear factor-κB

(2009) Jia Chang et al.   NATURE MEDICINE

Impaired DNA Damage Response, Genome Instability, and Tumorigenesis in SIRT1 Mutant Mice

(2008) Rui-Hong Wang et al.   CANCER CELL

SIRT1 Redistribution on Chromatin Promotes Genomic Stability but Alters Gene Expression during Aging

(2008) Philipp Oberdoerffer et al.   CELL

Resveratrol Delays Age-Related Deterioration and Mimics Transcriptional Aspects of Dietary Restriction without Extending Life Span

(2008) Kevin J. Pearson et al.   Cell Metabolism

SirT1 Gain of Function Increases Energy Efficiency and Prevents Diabetes in Mice

(2008) Alexander S. Banks et al.   Cell Metabolism

Liver diseases and metabolic syndrome

(2008) Sumio Watanabe et al.   JOURNAL OF GASTROENTEROLOGY

A mid-life crisis for aging theory

(2008) Ken Garber   NATURE BIOTECHNOLOGY

SirT1 Regulates Energy Metabolism and Response to Caloric Restriction in Mice

(2008) Gino Boily et al.   PLoS One

The SIRT1 Deacetylase Suppresses Intestinal Tumorigenesis and Colon Cancer Growth

(2008) Ron Firestein et al.   PLoS One

Sirt1 protects against high-fat diet-induced metabolic damage

(2008) P. T. Pfluger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA