Constitutive heterochromatin formation and transcription in mammals

Redundant Mechanisms to Form Silent Chromatin at Pericentromeric Regions Rely on BEND3 and DNA Methylation

(2014) Nehmé Saksouk et al.   MOLECULAR CELL

Hutchinson-Gilford progeria syndrome through the lens of transcription

(2013) Miron Prokocimer et al.   AGING CELL

LBR and Lamin A/C Sequentially Tether Peripheral Heterochromatin and Inversely Regulate Differentiation

(2013) Irina Solovei et al.   CELL

The chromatin remodelling complex NoRC safeguards genome stability by heterochromatin formation at telomeres and centromeres

(2013) Anna Postepska-Igielska et al.   EMBO REPORTS

Impaired replication elongation in Tetrahymena mutants deficient in histone H3 Lys 27 monomethylation

(2013) S. Gao et al.   GENES & DEVELOPMENT

Suv4-20h2 mediates chromatin compaction and is important for cohesin recruitment to heterochromatin

(2013) M. Hahn et al.   GENES & DEVELOPMENT

Regulation of Heterochromatin Transcription by Snail1/LOXL2 during Epithelial-to-Mesenchymal Transition

(2013) Alba Millanes-Romero et al.   MOLECULAR CELL

Prdm3 and Prdm16 are H3K9me1 Methyltransferases Required for Mammalian Heterochromatin Integrity

(2012) Inês Pinheiro et al.   CELL

Step-Wise Methylation of Histone H3K9 Positions Heterochromatin at the Nuclear Periphery

(2012) Benjamin D. Towbin et al.   CELL

Pericentric and centromeric transcription: a perfect balance required

(2012) Laura E. Hall et al.   CHROMOSOME RESEARCH

The BAH domain of ORC1 links H4K20me2 to DNA replication licensing and Meier–Gorlin syndrome

(2012) Alex J. Kuo et al.   NATURE

Histone methylation: a dynamic mark in health, disease and inheritance

(2012) Eric L. Greer et al.   NATURE REVIEWS GENETICS

A transcription factor–based mechanism for mouse heterochromatin formation

(2012) Aydan Bulut-Karslioglu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Association of UHRF1 with methylated H3K9 directs the maintenance of DNA methylation

(2012) Scott B Rothbart et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Heterochromatin Formation Promotes Longevity and Represses Ribosomal RNA Synthesis

(2012) Kimberly Larson et al.   PLoS Genetics

Dualistic function of Daxx at centromeric and pericentromeric heterochromatin in normal and stress conditions

(2012) Viacheslav M. Morozov et al.   Nucleus

SIRT1: roles in aging and cancer

(2011) Eun-Joo Kim et al.   BMB Reports

Mechanisms for the Inheritance of Chromatin States

(2011) Danesh Moazed   CELL

KDM2A represses transcription of centromeric satellite repeats and maintains the heterochromatic state

(2011) David Frescas et al.   CELL CYCLE

Regulation of chromatin by histone modifications

(2011) Andrew J Bannister et al.   CELL RESEARCH

Genomic size of CENP-A domain is proportional to total alpha satellite array size at human centromeres and expands in cancer cells

(2011) Lori L. Sullivan et al.   CHROMOSOME RESEARCH

Stabilization of Suv39H1 by SirT1 Is Part of Oxidative Stress Response and Ensures Genome Protection

(2011) Laia Bosch-Presegué et al.   MOLECULAR CELL

Maintenance of Silent Chromatin through Replication Requires SWI/SNF-like Chromatin Remodeler SMARCAD1

(2011) Samuel P. Rowbotham et al.   MOLECULAR CELL

BRCA1 tumour suppression occurs via heterochromatin-mediated silencing

(2011) Quan Zhu et al.   NATURE

The Polycomb complex PRC2 and its mark in life

(2011) Raphaël Margueron et al.   NATURE

WDHD1 modulates the post-transcriptional step of the centromeric silencing pathway

(2011) Chia-Ling Hsieh et al.   NUCLEIC ACIDS RESEARCH

Aberrant Overexpression of Satellite Repeats in Pancreatic and Other Epithelial Cancers

(2011) D. T. Ting et al.   SCIENCE

Mammalian Su(var) Genes in Chromatin Control

(2010) Barna D. Fodor et al.   Annual Review of Cell and Developmental Biology

Histone methyltransferase G9a contributes to H3K27 methylation in vivo

(2010) Hui Wu et al.   CELL RESEARCH

A Strand-Specific Burst in Transcription of Pericentric Satellites Is Required for Chromocenter Formation and Early Mouse Development

(2010) Aline.V. Probst et al.   DEVELOPMENTAL CELL

The NoRC complex mediates the heterochromatin formation and stability of silent rRNA genes and centromeric repeats

(2010) Claudio Guetg et al.   EMBO JOURNAL

Cell cycle-dependent accumulation of histone H3.3 and euchromatic histone modifications in pericentromeric heterochromatin in response to a decrease in DNA methylation levels

(2010) Kazuto Sugimura et al.   EXPERIMENTAL CELL RESEARCH

The death-associated protein DAXX is a novel histone chaperone involved in the replication-independent deposition of H3.3

(2010) P. Drane et al.   GENES & DEVELOPMENT

Jarid2 and PRC2, partners in regulating gene expression

(2010) G. Li et al.   GENES & DEVELOPMENT

JARID2 regulates binding of the Polycomb repressive complex 2 to target genes in ES cells

(2010) Diego Pasini et al.   NATURE

Human POGZ modulates dissociation of HP1α from mitotic chromosome arms through Aurora B activation

(2010) Ryu-Suke Nozawa et al.   NATURE CELL BIOLOGY

Heterochromatin formation in the mouse embryo requires critical residues of the histone variant H3.3

(2010) Angèle Santenard et al.   NATURE CELL BIOLOGY

Chromatin structure and the inheritance of epigenetic information

(2010) Raphaël Margueron et al.   NATURE REVIEWS GENETICS

Daxx is an H3.3-specific histone chaperone and cooperates with ATRX in replication-independent chromatin assembly at telomeres

(2010) P. W. Lewis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epigenetics: heterochromatin meets RNAi

(2009) Ingela Djupedal et al.   CELL RESEARCH

The Mi-2/NuRD complex associates with pericentromeric heterochromatin during S phase in rapidly proliferating lymphoid cells

(2009) Lisa Helbling Chadwick et al.   CHROMOSOMA

The HP1α–CAF1–SetDB1-containing complex provides H3K9me1 for Suv39-mediated K9me3 in pericentric heterochromatin

(2009) Alejandra Loyola et al.   EMBO REPORTS

Sirtuin/Sir2 phylogeny, evolutionary considerations and structural conservation

(2009) Sebastian Greiss et al.   MOLECULES AND CELLS

Ageing-related chromatin defects through loss of the NURD complex

(2009) Gianluca Pegoraro et al.   NATURE CELL BIOLOGY

A transcriptomic analysis of human centromeric and pericentric sequences in normal and tumor cells

(2009) Angéline Eymery et al.   NUCLEIC ACIDS RESEARCH

ICF, an immunodeficiency syndrome: DNA methyltransferase 3B involvement, chromosome anomalies, and gene dysregulation

(2008) Melanie Ehrlich et al.   AUTOIMMUNITY

Epigenetic Control of rDNA Loci in Response to Intracellular Energy Status

(2008) Akiko Murayama et al.   CELL

Functional Characterization of the Drosophila Hmt4-20/Suv4-20 Histone Methyltransferase

(2008) A. Sakaguchi et al.   GENETICS

Di-methyl H4 Lysine 20 Targets the Checkpoint Protein Crb2 to Sites of DNA Damage

(2008) Nikole T. Greeson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HP1 Proteins Form Distinct Complexes and Mediate Heterochromatic Gene Silencing by Nonoverlapping Mechanisms

(2008) Mohammad R. Motamedi et al.   MOLECULAR CELL

Cell cycle control of centromeric repeat transcription and heterochromatin assembly

(2008) Ee Sin Chen et al.   NATURE

PRC1 and Suv39h specify parental asymmetry at constitutive heterochromatin in early mouse embryos

(2008) Mareike Puschendorf et al.   NATURE GENETICS

Structural insights into human KAP1 PHD finger–bromodomain and its role in gene silencing

(2008) Lei Zeng et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY