When one becomes many-Alternative splicing in β-cell function and failure
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Title
When one becomes many-Alternative splicing in β-cell function and failure
Authors
Keywords
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Journal
DIABETES OBESITY & METABOLISM
Volume 20, Issue -, Pages 77-87
Publisher
Wiley
Online
2018-09-19
DOI
10.1111/dom.13388
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Note: Only part of the references are listed.- The Expanding Landscape of Alternative Splicing Variation in Human Populations
- (2018) Eddie Park et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Alternative splicing in cancers: From aberrant regulation to new therapeutics
- (2018) Xiaowei Song et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Identification of protein features encoded by alternative exons using Exon Ontology
- (2017) Léon-Charles Tranchevent et al. GENOME RESEARCH
- SRSF6-regulated alternative splicing that promotes tumour progression offers a therapy target for colorectal cancer
- (2017) Ledong Wan et al. GUT
- Faulty RNA splicing: consequences and therapeutic opportunities in brain and muscle disorders
- (2017) Vittoria Pagliarini et al. HUMAN GENETICS
- Spinal muscular atrophy: antisense oligonucleotide therapy opens the door to an integrated therapeutic landscape
- (2017) Matthew J.A. Wood et al. HUMAN MOLECULAR GENETICS
- Neuron-enriched RNA-binding Proteins Regulate Pancreatic Beta Cell Function and Survival
- (2017) Jonàs Juan-Mateu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Single-Cell Alternative Splicing Analysis with Expedition Reveals Splicing Dynamics during Neuron Differentiation
- (2017) Yan Song et al. MOLECULAR CELL
- Mechanistic insights into precursor messenger RNA splicing by the spliceosome
- (2017) Yigong Shi NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Alternative splicing as a regulator of development and tissue identity
- (2017) Francisco E. Baralle et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- ASpedia: a comprehensive encyclopedia of human alternative splicing
- (2017) Daejin Hyung et al. NUCLEIC ACIDS RESEARCH
- Eteplirsen in the treatment of Duchenne muscular dystrophy
- (2017) Kenji Rowel Lim et al. Drug Design Development and Therapy
- Development of Exon Skipping Therapies for Duchenne Muscular Dystrophy: A Critical Review and a Perspective on the Outstanding Issues
- (2017) Annemieke Aartsma-Rus et al. Nucleic Acid Therapeutics
- The Functional Impact of Alternative Splicing in Cancer
- (2017) Héctor Climente-González et al. Cell Reports
- Type 1 Diabetes Candidate Genes Linked to Pancreatic Islet Cell Inflammation and Beta-Cell Apoptosis
- (2017) Joachim Størling et al. Genes
- REST, a master regulator of neurogenesis, evolved under strong positive selection in humans and in non human primates
- (2017) Alessandra Mozzi et al. Scientific Reports
- A nanobody-based tracer targeting DPP6 for non-invasive imaging of human pancreatic endocrine cells
- (2017) Alexander Balhuizen et al. Scientific Reports
- RNA-binding protein HuD reduces triglyceride production in pancreatic β cells by enhancing the expression of insulin-induced gene 1
- (2016) Chongtae Kim et al. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- ExonImpact: Prioritizing Pathogenic Alternative Splicing Events
- (2016) Meng Li et al. HUMAN MUTATION
- JNK Signaling: Regulation and Functions Based on Complex Protein-Protein Partnerships
- (2016) András Zeke et al. MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS
- Viral infections in type 1 diabetes mellitus — why the β cells?
- (2016) Anne Op de Beeck et al. Nature Reviews Endocrinology
- The roles of RNA processing in translating genotype to phenotype
- (2016) Kassie S. Manning et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Integrating transcriptome and proteome profiling: Strategies and applications
- (2016) Dhirendra Kumar et al. PROTEOMICS
- Developmental regulation of RNA processing by Rbfox proteins
- (2016) John G. Conboy Wiley Interdisciplinary Reviews-RNA
- NOVA2-mediated RNA regulation is required for axonal pathfinding during development
- (2016) Yuhki Saito et al. eLife
- Prediction and Quantification of Splice Events from RNA-Seq Data
- (2016) Leonard D. Goldstein et al. PLoS One
- Insulin receptor alternative splicing is regulated by insulin signaling and modulates beta cell survival
- (2016) Pushkar Malakar et al. Scientific Reports
- MECHANISMS IN ENDOCRINOLOGY: Alternative splicing: the new frontier in diabetes research
- (2015) Jonàs Juan-Mateu et al. EUROPEAN JOURNAL OF ENDOCRINOLOGY
- The RNA-binding protein Rbfox1 regulates splicing required for skeletal muscle structure and function
- (2015) Simona Pedrotti et al. HUMAN MOLECULAR GENETICS
- The Role of Alternative Splicing in the Control of Immune Homeostasis and Cellular Differentiation
- (2015) Mehmet Yabas et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Regulation of Splicing Factors by Alternative Splicing and NMD Is Conserved between Kingdoms Yet Evolutionarily Flexible
- (2015) Liana F. Lareau et al. MOLECULAR BIOLOGY AND EVOLUTION
- HISAT: a fast spliced aligner with low memory requirements
- (2015) Daehwan Kim et al. NATURE METHODS
- RNA mis-splicing in disease
- (2015) Marina M. Scotti et al. NATURE REVIEWS GENETICS
- Spinal muscular atrophy—recent therapeutic advances for an old challenge
- (2015) Irene Faravelli et al. Nature Reviews Neurology
- Alternative Splicing in the Mammalian Nervous System: Recent Insights into Mechanisms and Functional Roles
- (2015) Bushra Raj et al. NEURON
- SplicePie: a novel analytical approach for the detection of alternative, non-sequential and recursive splicing
- (2015) Irina Pulyakhina et al. NUCLEIC ACIDS RESEARCH
- Trimmomatic: a flexible trimmer for Illumina sequence data
- (2014) Anthony M. Bolger et al. BIOINFORMATICS
- A Highly Conserved Program of Neuronal Microexons Is Misregulated in Autistic Brains
- (2014) Manuel Irimia et al. CELL
- Splicing factor SRSF6 promotes hyperplasia of sensitized skin
- (2014) Mads A Jensen et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Nova1 is a master regulator of alternative splicing in pancreatic beta cells
- (2014) Olatz Villate et al. NUCLEIC ACIDS RESEARCH
- rMATS: Robust and flexible detection of differential alternative splicing from replicate RNA-Seq data
- (2014) Shihao Shen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Alternative Splice Forms of CTLA-4 Induced by Antisense Mediated Splice-Switching Influences Autoimmune Diabetes Susceptibility in NOD Mice
- (2014) Dan V. Mourich et al. Nucleic Acid Therapeutics
- RNAmotifs: prediction of multivalent RNA motifs that control alternative splicing
- (2014) Matteo Cereda et al. GENOME BIOLOGY
- ASPeak: an abundance sensitive peak detection algorithm for RIP-Seq
- (2013) A. Kucukural et al. BIOINFORMATICS
- The impact of splicing on protein domain architecture
- (2013) Sara Light et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- RNA Sequencing Identifies Dysregulation of the Human Pancreatic Islet Transcriptome by the Saturated Fatty Acid Palmitate
- (2013) Miriam Cnop et al. DIABETES
- Candidate genes for type 1 diabetes modulate pancreatic islet inflammation andβ-cell apoptosis
- (2013) I. Santin et al. DIABETES OBESITY & METABOLISM
- Characterization of PTPN2 and its use as a biomarker
- (2013) Stéphanie Bussières-Marmen et al. METHODS
- Genome-wide Analysis Reveals SR Protein Cooperation and Competition in Regulated Splicing
- (2013) Shatakshi Pandit et al. MOLECULAR CELL
- Alternative splicing: a pivotal step between eukaryotic transcription and translation
- (2013) Alberto R. Kornblihtt et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Rbfox proteins regulate alternative mRNA splicing through evolutionarily conserved RNA bridges
- (2013) Michael T Lovci et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- GLIS3, a Susceptibility Gene for Type 1 and Type 2 Diabetes, Modulates Pancreatic Beta Cell Apoptosis via Regulation of a Splice Variant of the BH3-Only Protein Bim
- (2013) Tatiane C. Nogueira et al. PLoS Genetics
- Targeting RNA splicing for disease therapy
- (2013) Mallory A. Havens et al. Wiley Interdisciplinary Reviews-RNA
- Site identification in high-throughput RNA–protein interaction data
- (2012) Philip J. Uren et al. BIOINFORMATICS
- STAR: ultrafast universal RNA-seq aligner
- (2012) Alexander Dobin et al. BIOINFORMATICS
- Challenges in estimating percent inclusion of alternatively spliced junctions from RNA-seq data
- (2012) Boyko Kakaradov et al. BMC BIOINFORMATICS
- Detecting differential usage of exons from RNA-seq data
- (2012) S. Anders et al. GENOME RESEARCH
- TAK1, more than just innate immunity
- (2012) Liang Dai et al. IUBMB LIFE
- Antisense-based therapy for the treatment of spinal muscular atrophy
- (2012) Frank Rigo et al. JOURNAL OF CELL BIOLOGY
- Streaming fragment assignment for real-time analysis of sequencing experiments
- (2012) Adam Roberts et al. NATURE METHODS
- Dantrolene Enhances Antisense-Mediated Exon Skipping in Human and Mouse Models of Duchenne Muscular Dystrophy
- (2012) G. C. Kendall et al. Science Translational Medicine
- Pre-mRNA splicing in disease and therapeutics
- (2012) Ravi K. Singh et al. TRENDS IN MOLECULAR MEDICINE
- The Human Pancreatic Islet Transcriptome: Expression of Candidate Genes for Type 1 Diabetes and the Impact of Pro-Inflammatory Cytokines
- (2012) Décio L. Eizirik et al. PLoS Genetics
- β-Cell evolution: How the pancreas borrowed from the brain
- (2011) Margot E. Arntfield et al. BIOESSAYS
- Comparative analysis of RNA-Seq alignment algorithms and the RNA-Seq unified mapper (RUM)
- (2011) Gregory R. Grant et al. BIOINFORMATICS
- RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome
- (2011) Bo Li et al. BMC BIOINFORMATICS
- PTPN2, a Candidate Gene for Type 1 Diabetes, Modulates Pancreatic -Cell Apoptosis via Regulation of the BH3-Only Protein Bim
- (2011) I. Santin et al. DIABETES
- Reduced fidelity of branch point recognition and alternative splicing induced by the anti-tumor drug spliceostatin A
- (2011) A. Corrionero et al. GENES & DEVELOPMENT
- Understanding splicing regulation through RNA splicing maps
- (2011) Joshua T. Witten et al. TRENDS IN GENETICS
- The interferon regulatory factor 5 gene confers susceptibility to rheumatoid arthritis and influences its erosive phenotype
- (2010) K. Dawidowicz et al. ANNALS OF THE RHEUMATIC DISEASES
- Fast and SNP-tolerant detection of complex variants and splicing in short reads
- (2010) T. D. Wu et al. BIOINFORMATICS
- RNAstructure: software for RNA secondary structure prediction and analysis
- (2010) Jessica S Reuter et al. BMC BIOINFORMATICS
- NGSQC: cross-platform quality analysis pipeline for deep sequencing data
- (2010) Manhong Dai et al. BMC GENOMICS
- A genomic-based approach identifies FXYD domain containing ion transport regulator 2 (FXYD2)γa as a pancreatic beta cell-specific biomarker
- (2010) D. Flamez et al. DIABETOLOGIA
- Alternative Splicing Factor/Splicing Factor 2 Regulates the Expression of the ζ Subunit of the Human T Cell Receptor-associated CD3 Complex
- (2010) Vaishali R. Moulton et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities
- (2010) Sven Heinz et al. MOLECULAR CELL
- Transcriptome genetics using second generation sequencing in a Caucasian population
- (2010) Stephen B. Montgomery et al. NATURE
- Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation
- (2010) Cole Trapnell et al. NATURE BIOTECHNOLOGY
- Analysis and design of RNA sequencing experiments for identifying isoform regulation
- (2010) Yarden Katz et al. NATURE METHODS
- MapSplice: Accurate mapping of RNA-seq reads for splice junction discovery
- (2010) Kai Wang et al. NUCLEIC ACIDS RESEARCH
- TopHat: discovering splice junctions with RNA-Seq
- (2009) Cole Trapnell et al. BIOINFORMATICS
- edgeR: a Bioconductor package for differential expression analysis of digital gene expression data
- (2009) M. D. Robinson et al. BIOINFORMATICS
- CLIP: Construction of cDNA libraries for high-throughput sequencing from RNAs cross-linked to proteins in vivo
- (2009) Zhen Wang et al. METHODS
- Baxβ: A Constitutively Active Human Bax Isoform that Is under Tight Regulatory Control by the Proteasomal Degradation Mechanism
- (2009) Nai Yang Fu et al. MOLECULAR CELL
- The role of inflammation in insulitis and β-cell loss in type 1 diabetes
- (2009) Décio L. Eizirik et al. Nature Reviews Endocrinology
- Mechanisms of alternative splicing regulation: insights from molecular and genomics approaches
- (2009) Mo Chen et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- A hierarchical Bayesian model for comparing transcriptomes at the individual transcript isoform level
- (2009) Sika Zheng et al. NUCLEIC ACIDS RESEARCH
- MEME SUITE: tools for motif discovery and searching
- (2009) T. L. Bailey et al. NUCLEIC ACIDS RESEARCH
- Pentamidine reverses the splicing defects associated with myotonic dystrophy
- (2009) M. B. Warf et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Alternative Splicing of CD45: The Tip of the Iceberg
- (2008) Julie Zikherman et al. IMMUNITY
- Alternative isoform regulation in human tissue transcriptomes
- (2008) Eric T. Wang et al. NATURE
- Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing
- (2008) Qun Pan et al. NATURE GENETICS
- Tissue-specific splicing factor gene expression signatures
- (2008) Ana Rita Grosso et al. NUCLEIC ACIDS RESEARCH
- JunB Inhibits ER Stress and Apoptosis in Pancreatic Beta Cells
- (2008) Esteban N. Gurzov et al. PLoS One
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